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41. 发明授权

US06358228B1 Vasoocclusive device including asymmetrical pluralities of fibers 有权
标题翻译：血管收缩装置包括不对称的多个纤维
公开(公告)号：US06358228B1
公开(公告)日：2002-03-19
申请号：US09286774
申请日：1999-04-06
申请人： David E. Tubman , Thomas A. Osborne
发明人： David E. Tubman , Thomas A. Osborne
IPC分类号： A61M2900
CPC分类号： A61B17/12022 , A61B17/00491 , A61B17/0057 , A61B17/12131 , A61B17/1215 , A61B17/12181 , A61B90/39 , A61B2017/00575 , A61B2017/1205
摘要： A vasoocclusive device 10 is adapted for introduction into a vessel of a human or veterinary patient and occluding flow through the vessel. The device 10 includes a radiopaque member 12 (such as a metallic coil 14) having a proximal end 16 and a distal end 18, the distal end 18 being introduced first into the vessel. The member 12 is about 1.5 mm to about 3.0 mm long and no more than about 2.7 mm wide, preferably about 0.25 to 0.4 mm wide. The device 10 also includes a distal plurality 20 of fibers having an average distal fiber length, associated with and extending away from the distal end 18 of the member 12, as well as a proximal plurality 24 of fibers having an average proximal fiber length, associated with and extending away from the proximal end 16 of the member 12. The average proximal fiber length is about two to about five times the average distal fiber length. The average distal fiber length is preferably about 4 to 8 mm, while the average proximal fiber length is preferably about 9 to 15 mm. The distal and proximal pluralities 20 and 24 of fibers each preferably include 8 to 10 individual fibers composed of polyester, nylon or silk of about 40 denier. The vasoocclusive device 10 is particularly advantageous in that it can be used in vessels which are significantly narrower than those in which prior devices could be used, yet its asymmetric arrangement of the distal and proximal pluralities 20 and 24 of fibers allows it to enjoy significantly improved lodging in such narrow vessels.
摘要翻译：血管收缩装置10适于引入人或兽医患者的血管并阻塞通过血管的流动。装置10包括具有近端16和远端18的不透射线构件12（例如金属线圈14），远端18首先被引入容器。构件12的长度为约1.5mm至约3.0mm，宽度不大于约2.7mm，优选为约0.25至0.4mm宽。装置10还包括具有与构件12的远端18相关联并远离构件12的远端纤维长度的平均远端纤维长度的远端多个纤维20以及具有平均近端纤维长度的近端多个纤维24，其具有相关联的远离构件12的近端16并且远离构件12的近端16.平均近端纤维长度为平均远端纤维长度的约2至约5倍。平均末端纤维长度优选为约4至8mm，而平均近纤维长度优选为约9至15mm。纤维的远端和近端多个20和24各自优选包括由约40旦尼尔的聚酯，尼龙或丝组成的8至10个单独纤维。血管闭塞装置10是特别有利的，因为它可以用于明显比可以使用现有装置的容器窄的容器，但是其纤维的远端和近端多个20和24的不对称布置允许其显着改善住在这样狭窄的船只。

42. 发明授权

US5690642A Rapid exchange stent delivery balloon catheter 失效
标题翻译：快速交换支架输送球囊导管
公开(公告)号：US5690642A
公开(公告)日：1997-11-25
申请号：US582338
申请日：1996-01-18
申请人： Thomas A. Osborne , Scott E. Eells
发明人： Thomas A. Osborne , Scott E. Eells
IPC分类号： A61M25/00 , A61B19/00 , A61F2/958 , A61M29/02 , A61F11/00
CPC分类号： A61F2/958 , A61B90/39 , A61M2025/0183 , A61M2025/1056 , A61M25/104
摘要： A rapid exchange stent delivery balloon catheter which allows exchange from a balloon angioplasty catheter to a stent delivery catheter without the need to replace the angioplasty catheter wire guide with an exchange-length wire guide before exchanging the stent delivery catheter for the balloon angioplasty catheter. The stent delivery catheter of the present invention includes a relatively short wire guide shaft which is bonded to the catheter shaft only at a location distal to the inflation lumen.
摘要翻译：快速交换支架输送球囊导管，其允许从球囊血管成形术导管到支架输送导管的交换，而不需要在更换用于球囊血管成形术导管的支架输送导管之前用交换长度导线引导器替换血管成形术导管导线器。本发明的支架输送导管包括相对较短的线引导轴，其仅在远离膨胀腔的位置处结合到导管轴。

43. 发明授权

US5324257A Balloon catheter having an integrally formed guide wire channel 失效
标题翻译：气球导管具有整体形成的导丝通道
公开(公告)号：US5324257A
公开(公告)日：1994-06-28
申请号：US878036
申请日：1992-05-04
申请人： Thomas A. Osborne , Arne Molgaard-Nielsen
发明人： Thomas A. Osborne , Arne Molgaard-Nielsen
IPC分类号： A61M29/02 , A61M31/00
CPC分类号： A61M25/104 , A61M2025/0183 , A61M2025/1079
摘要： A balloon catheter for performing angioplasty procedures includes a catheter shaft, a balloon attached to the catheter shaft near the distal end and a channel either attached to or integrally formed on the distal end of the catheter shaft distally of the balloons. The relatively short channel is threaded over a wire guide for advancing the balloon catheter into the vascular system of the patient over the wire guide. The relatively short channel allows the balloon catheter to be advanced along the wire guide with less friction interaction between the balloon catheter and wire guide than in conventional balloon catheters in which the wire guide lumen extends the full length of the catheter.
摘要翻译：用于执行血管成形术程序的气囊导管包括导管轴，附接到远端末端的导管轴的球囊，以及附接到导管轴远端的整体形成的通道。相对较短的通道穿过线引导件，用于使气囊导管通过导线器前进到患者的血管系统中。相对较短的通道允许气囊导管沿导线引导件前进，而球囊导管和导线引导件之间的摩擦相互作用小于常规气囊导管，其中导线腔延伸导管的整个长度。

44. 外观设计

USD286677S Digital subtraction angiography needle 失效
公开(公告)号：USD286677S
公开(公告)日：1986-11-11
申请号：US576218
申请日：1984-02-02
申请人： Thomas A. Osborne
设计人： Thomas A. Osborne

45. 发明授权

US4586926A Percutaneous entry needle 失效
标题翻译：经皮进针
公开(公告)号：US4586926A
公开(公告)日：1986-05-06
申请号：US585950
申请日：1984-03-05
申请人： Thomas A. Osborne
发明人： Thomas A. Osborne
IPC分类号： A61M5/158 , A61M27/00
CPC分类号： A61M5/158 , A61M5/3286
摘要： A percutaneous entry needle for use in digital subtraction angiography procedures. The needle includes tubing having one end sharpened for percutaneous entry by a bevel that is at an acute angle to the axis of the tubing. The tubing has a sharp tip defined by the bevel which tip is located on one side of the tubing. A hub is rigidly secured to the other end of the tubing and includes oppositely projecting luer lock ears which project radially from the axis in directions which are at 90.degree. to the position of the sharp tip relative to the axis. There is also provided a rigid flange rigidly secured to the hub and extending radially thereof. The flange is located on the side of the tubing away from the sharp tip and is appropriately sized for gripping by the user.
摘要翻译：用于数字减影血管造影手术的经皮进针。针头包括具有尖端的管道，其一端通过与管道的轴线成锐角的斜面进行经皮进入。管道具有由斜面限定的尖端，尖端位于管道的一侧。轮毂刚性地固定在管道的另一端，并且包括相对突出的鲁尔锁耳，其从轴线径向突出，该方向与尖端相对于轴线的位置成90°。还提供刚性地固定到轮毂并且径向延伸的刚性凸缘。该凸缘位于远离锋利尖端的管的侧面上，并且适当地定尺寸以便使用者握紧。

46. 发明授权

US4548206A Catheter wire guide with movable mandril 失效
标题翻译：导管导丝带可移动的心轴
公开(公告)号：US4548206A
公开(公告)日：1985-10-22
申请号：US515636
申请日：1983-07-21
申请人： Thomas A. Osborne
发明人： Thomas A. Osborne
IPC分类号： A61M25/01 , A61B5/02 , A61M23/00 , A61M25/00 , A61M25/09
CPC分类号： A61M25/09033 , A61M25/09025 , A61M2025/09175
摘要： A catheter wire guide having an axially movable mandril with a tapered tip for permitting the flexibility of the distal tip of the wire guide to be varied. The mandril is coated with a lubricating material, such as Teflon, for facilitating the smooth movement of the mandril within the wire guide.
摘要翻译：一种具有轴向移动的心轴的导管导线器，其具有锥形尖端，以允许导线引导件的远端尖端的柔性变化。曼陀罗涂覆有润滑材料，如特氟隆，以促进曼尼尔在导丝器内的平稳运动。

47. 发明授权

US09301764B2 Occluding device and method of occluding fluid flow through a body vessel 有权
标题翻译：阻塞液体流过身体容器的封闭装置和方法
公开(公告)号：US09301764B2
公开(公告)日：2016-04-05
申请号：US10884728
申请日：2004-07-02
申请人： Robert I. White, Jr. , Thomas A. Osborne , Kurt J. Tekulve
发明人： Robert I. White, Jr. , Thomas A. Osborne , Kurt J. Tekulve
IPC分类号： A61B17/12
CPC分类号： A61B17/1215 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12145 , A61B2017/1205
摘要： An occluding device for occluding fluid flow through a lumen of a body vessel. The device comprises a coil and fibers attached to the coil. The coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed. The fibers extend from the coil at a length.
摘要翻译：用于阻塞流体流过身体血管的内腔的闭塞装置。该装置包括线圈和附接到线圈的纤维。线圈具有约5至60克的初始张力，以方便线圈在展开时折叠。纤维从线圈延伸一段长度。

48. 发明授权

US08808351B2 Stretchable prosthesis fenestration 有权
标题翻译：伸展假体开窗
公开(公告)号：US08808351B2
公开(公告)日：2014-08-19
申请号：US10962632
申请日：2004-10-12
申请人： Thomas A. Osborne
发明人： Thomas A. Osborne
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/061 , A61F2002/075 , A61F2002/821
摘要： A prosthesis (10) having a variable size or stretchable fenestration (14) in the graft material (37) of a biocompatible tubular graft (11). An expandable frame (16) is disposed about the fenestration, and a portion (17) of the graft material about the fenestration is folded back over the frame to cover the frame. Additional grafts or prosthesis of varying size can be inserted through the frame and fenestration with the stretched frame and folded portion compressing on the inserted graft forming a seal therewith.
摘要翻译：在生物相容的管状移植物（11）的移植材料（37）中具有可变尺寸或可拉伸的开窗（14）的假体（10）。围绕开窗设置可膨胀框架（16），围绕开窗的移植材料的一部分（17）被折回到框架上以覆盖框架。可以通过框架插入不同尺寸的附加移植物或假体，并用拉伸的框架进行开窗，并且在插入的移植物上的折叠部分压缩形成与其的密封。

49. 发明授权

US08709060B2 Prosthesis deployment system 有权
标题翻译：假体部署系统
公开(公告)号：US08709060B2
公开(公告)日：2014-04-29
申请号：US12158400
申请日：2006-12-22
申请人： Thomas A. Osborne
发明人： Thomas A. Osborne
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2002/9511 , A61F2002/9517 , A61F2002/9665
摘要： A trigger wire release mechanism is disclosed that includes a control member for selectively releasing a trigger wire (22, 44) from a prosthesis retaining device. The control member includes an elongate body member (36) and a guide member (24, 25, 93, 94) slidably disposed on the elongate body member. The trigger wire 1 (22, 44) includes a distal end coupled to the prosthesis retaining device and a proximal end coupled to the guide member. The guide member (24, 25, 93, 94) can be moved from a distal end of the elongate body (36) to a proximal end of the elongate body, thereby disengaging the trigger wire (22, 44) from the retaining device. The control member may include a locking mechanism (120) for limiting the axial position of the guide member (24, 25, 93, 94) along the elongate body member (36). A prosthesis control member (81) is also disclosed. The prosthesis control member (81) is adapted to control the position of the prosthesis during deployment.
摘要翻译：公开了一种触发线释放机构，其包括用于从假体保持装置选择性地释放触发线（22,44）的控制构件。控制构件包括细长主体构件（36）和可滑动地设置在细长主体构件上的引导构件（24,25,93,94）。触发线1（22,44）包括联接到假体保持装置的远端和联接到引导构件的近端。引导构件（24,25,93,94）可以从细长体（36）的远端移动到细长体的近端，从而使触发线（22,44）与保持装置分离。控制构件可以包括用于限制引导构件（24,25,93,94）沿着细长主体构件（36）的轴向位置的锁定机构（120）。还公开了假体控制构件（81）。假体控制构件（81）适于在展开期间控制假体的位置。

50. 发明申请

US20120253446A1 Valve Device with Inflatable Chamber 审中-公开
标题翻译：带充气舱的阀门装置
公开(公告)号：US20120253446A1
公开(公告)日：2012-10-04
申请号：US13493563
申请日：2012-06-11
申请人： Thomas A. Osborne , Jacob A. Flagle , John A. Brumleve
发明人： Thomas A. Osborne , Jacob A. Flagle , John A. Brumleve
IPC分类号： A61F2/84 , B21D53/00
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2475 , A61F2220/0008 , A61F2220/0016 , A61F2230/0026 , A61F2230/0095 , A61F2250/0003 , Y10T29/494
摘要： Prosthetic valve devices for implantation in body vessels are provided. The prosthetic valve device includes at least one flexible member that permits fluid flow in a first direction and substantially prevents fluid flow in a second. The valve device also includes an inflatable chamber at least partially attached to the flexible member. The inflatable chamber is adapted to receive inflating media and is adapted to contact the body vessel. A delivery system is also provided that includes a valve device and a delivery apparatus. The delivery apparatus includes a member adapted for filling the chamber of the valve device with inflating media. A related method of making the valve device is also provided.
摘要翻译：提供用于植入体内血管的假体瓣膜装置。所述人工瓣膜装置包括至少一个柔性构件，其允许流体沿第一方向流动并且基本上防止流体在第二方向流动。阀装置还包括至少部分地附接到柔性构件的可充气室。充气室适于接收充气介质并且适于接触身体容器。还提供了包括阀装置和输送装置的输送系统。输送装置包括适于用充气介质填充阀装置的室的构件。还提供了制造阀装置的相关方法。

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