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1. 发明授权

US09301764B2 Occluding device and method of occluding fluid flow through a body vessel 有权
标题翻译：阻塞液体流过身体容器的封闭装置和方法
公开(公告)号：US09301764B2
公开(公告)日：2016-04-05
申请号：US10884728
申请日：2004-07-02
申请人： Robert I. White, Jr. , Thomas A. Osborne , Kurt J. Tekulve
发明人： Robert I. White, Jr. , Thomas A. Osborne , Kurt J. Tekulve
IPC分类号： A61B17/12
CPC分类号： A61B17/1215 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12145 , A61B2017/1205
摘要： An occluding device for occluding fluid flow through a lumen of a body vessel. The device comprises a coil and fibers attached to the coil. The coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed. The fibers extend from the coil at a length.
摘要翻译：用于阻塞流体流过身体血管的内腔的闭塞装置。该装置包括线圈和附接到线圈的纤维。线圈具有约5至60克的初始张力，以方便线圈在展开时折叠。纤维从线圈延伸一段长度。

2. 发明授权

US07595082B2 Wire guide 有权
标题翻译：导线导轨
公开(公告)号：US07595082B2
公开(公告)日：2009-09-29
申请号：US10813423
申请日：2004-03-30
申请人： John J. Connors, III , Kurt J. Tekulve , Thomas A. Osborne
发明人： John J. Connors, III , Kurt J. Tekulve , Thomas A. Osborne
IPC分类号： B05D3/12 , A61M25/09 , A61M31/00
CPC分类号： A61M25/09 , A61M25/01 , A61M2025/09133 , A61M2025/09175
摘要： A wire guide includes a mandrel that has a proximal portion and a distal portion. A first coating with a low coefficient of friction is disposed on the proximal portion of the mandrel. A second coating is disposed on the distal portion of the mandrel, where the second coating provides a sub-structure. A third coating is disposed on the second coating, where the third coating comprises a surface that allows for easy maneuverability of the wire guide. The first coating on the proximal portion provides enough lubricity to keep the wire guide from becoming bound or stuck in a catheter or medical device while still allowing a user to have a good grip of the wire guide. The second coating on the distal portion provides lubricity for the wire guide, which allows the user to easily maneuver the wire guide through a vascular anatomy.
摘要翻译：线引导件包括具有近端部分和远端部分的心轴。具有低摩擦系数的第一涂层设置在心轴的近端部分上。第二涂层设置在心轴的远端部分上，其中第二涂层提供子结构。第三涂层设置在第二涂层上，其中第三涂层包括允许导线器易于操作的表面。近端部分上的第一涂层提供足够的润滑性以保持线引导件不会被粘合或卡在导管或医疗装置中，同时仍然允许使用者具有良好的电线导向器的抓地力。远端部分上的第二涂层为线引导件提供润滑性，其允许使用者容易地通过血管解剖结构操纵线引导件。

3. 发明授权

US06544269B2 Localizer needle 有权
公开(公告)号：US06544269B2
公开(公告)日：2003-04-08
申请号：US09897246
申请日：2001-07-02
申请人： Thomas A. Osborne , Kurt J. Tekulve
发明人： Thomas A. Osborne , Kurt J. Tekulve
IPC分类号： A61B1734
CPC分类号： A61B90/39 , A61B2017/00349 , A61B2090/3908
摘要： A medical device (10) includes at least a stylet (12) for establishing the location of tissue of interest, such as a nonpalpable lesion in breast tissue. The device may also include a needle assembly (14) and an aspiration syringe (16). The medical device (10) can most readily be understood as an improvement in Kopans-type or hookwire-type localizer stylet having a wire shaft (18) with a distal end (28), and a hook (36) depending in a proximal direction from the wire shaft (18). The improvements entail spacing the hook (36) proximally of the distal end (28) of the wire shaft (18), and providing the wire shaft with a twist between the hook (36) and the distal end (28) of the wire shaft (18). Wire shaft (18) has first and second wire segments (20 and 30), each including a respective distal twisted portion (24 or 34) adjacent its respective distal end (22 or 32). The first wire segment (20) further includes a generally straight portion (26) extending proximally of its distal twisted portion (24), while the second wire segment (30) further includes a hook (36) extending proximally of its distal twisted portion (34).

4. 发明授权

US07001345B2 Wire guide 有权
公开(公告)号：US07001345B2
公开(公告)日：2006-02-21
申请号：US10227048
申请日：2002-08-23
申请人： John J. Connors, III , Kurt J. Tekulve , Thomas A. Osborne
发明人： John J. Connors, III , Kurt J. Tekulve , Thomas A. Osborne
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61M25/09 , A61M25/01 , A61M2025/09133 , A61M2025/09175
摘要： A wire guide includes a mandrel that has a proximal portion and a distal portion. A first coating with a low coefficient of friction is disposed on the proximal portion of the mandrel. A second coating is disposed on the distal portion of the mandrel, where the second coating provides a sub-structure. A third coating is disposed on the second coating, where the third coating comprises a surface that allows for easy maneuverability of the wire guide. The first coating on the proximal portion provides enough lubricity to keep the wire guide from becoming bound or stuck in a catheter or medical device while still allowing a user to have a good grip of the wire guide. The second coating on the distal portion provides lubricity for the wire guide, which allows the user to easily maneuver the wire guide through a vascular anatomy.

5. 发明申请

US20100087780A1 Wire Guide having Variable Flexibility and Method of Use Thereof 审中-公开
标题翻译：具有可变灵活性的导线及其使用方法
公开(公告)号：US20100087780A1
公开(公告)日：2010-04-08
申请号：US12245161
申请日：2008-10-03
申请人： Kurt J. Tekulve , Thomas A. Osborne
发明人： Kurt J. Tekulve , Thomas A. Osborne
IPC分类号： A61M25/092 , A61M25/09
CPC分类号： A61M25/09025 , A61M2025/09083 , A61M2025/0915
摘要： The present invention generally relates to a medical surgical device and specifically a wire guide for percutaneous placement within a body lumen. The flexibility of the wire guide may be varied while it is in place within the body lumen. One embodiment of the wire guide includes and a distal tip positioned at the distal end of the coil. A plurality of core members are positioned side by side within the lumen. Methods of using the wire guide are also provided.
摘要翻译：本发明总体上涉及一种医疗手术装置，具体地说涉及一种用于在体腔内经皮放置的导丝器。线引导件的柔性可以在其在体腔内就位时变化。线引导件的一个实施例包括位于线圈远端的远端。多个芯构件并排设置在内腔内。还提供了使用导线器的方法。

6. 发明授权

US09498271B2 Coaxial needle cannula with distal spiral mixer and side ports for fluid injection 有权
标题翻译：同轴针套管与远端螺旋混合器和侧面端口用于注射液体
公开(公告)号：US09498271B2
公开(公告)日：2016-11-22
申请号：US12914167
申请日：2010-10-28
申请人： Thomas A. Osborne , Jeffry S. Melsheimer , Christopher D. Bosel
发明人： Thomas A. Osborne , Jeffry S. Melsheimer , Christopher D. Bosel
IPC分类号： A61B17/88 , A61M5/315 , B01F5/06 , A61M5/19
CPC分类号： A61J1/20 , A61B17/8816 , A61B17/8822 , A61B18/06 , A61B2017/8838 , A61M5/19 , A61M5/31581 , B01F5/0473 , B01F5/0614 , B01F5/0615 , B01F2215/0029
摘要： Disclosed is a multi-lumen mixing device that includes a first and second lumen constructed and arranged to separately pass a first and second reagent to a mixing chamber in the device, where the mixing chamber includes a mixing feature that mixes the first and second reagents. The disclosed multi-lumen mixing device may also include a port in fluid communication with the reaction mixing to permit the product of the combined reagents to be injected into a patent.
摘要翻译：公开了一种多腔混合装置，其包括构造和布置成将第一和第二试剂分开地通过装置中的混合室的第一和第二腔，其中混合室包括混合第一和第二试剂的混合特征。所公开的多腔混合装置还可以包括与反应混合流体连通的端口，以允许将组合试剂的产物注入专利。

7. 发明授权

US08246672B2 Endovascular graft with separately positionable and removable frame units 有权
标题翻译：血管内移植物具有单独定位和可拆卸的框架单元
公开(公告)号：US08246672B2
公开(公告)日：2012-08-21
申请号：US12339596
申请日：2008-12-19
申请人： Thomas A. Osborne
发明人： Thomas A. Osborne
IPC分类号： A61F2/06
CPC分类号： A61F2/013 , A61F2/07 , A61F2/89 , A61F2002/016 , A61F2002/065 , A61F2002/9534 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/008 , A61F2230/0093
摘要： A device for repairing a vessel body including a plurality distinct and independently positionable, expandable frame units disposed within a tubular graft. The independent frame units are capable of being positioned, repositioned, or removed to conform the tubular graft to the anatomy of the vessel body.
摘要翻译：一种用于修理容器主体的装置，包括设置在管状移植物内的多个不同且可独立定位的可扩展框架单元。独立的框架单元能够定位，重新定位或移除以使管状移植物符合血管体的解剖结构。

8. 发明授权

US08197534B2 Valve device with inflatable chamber 有权
标题翻译：带充气室的阀门装置
公开(公告)号：US08197534B2
公开(公告)日：2012-06-12
申请号：US11394303
申请日：2006-03-30
申请人： Thomas A. Osborne , Jacob A. Flagle , John A. Brumleve
发明人： Thomas A. Osborne , Jacob A. Flagle , John A. Brumleve
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2475 , A61F2220/0008 , A61F2220/0016 , A61F2230/0026 , A61F2230/0095 , A61F2250/0003 , Y10T29/494
摘要： Prosthetic valve devices for implantation in body vessels are provided. The prosthetic valve device includes at least one flexible member that permits fluid flow in a first direction and substantially prevents fluid flow in a second. The valve device also includes an inflatable chamber at least partially attached to the flexible member. The inflatable chamber is adapted to receive inflating media and is adapted to contact the body vessel. A delivery system is also provided that includes a valve device and a delivery apparatus. The delivery apparatus includes a member adapted for filling the chamber of the valve device with inflating media. A related method of making the valve device is also provided.
摘要翻译：提供用于植入体内血管的假体瓣膜装置。所述人工瓣膜装置包括至少一个柔性构件，其允许流体沿第一方向流动并且基本上防止流体在第二方向流动。阀装置还包括至少部分地附接到柔性构件的可充气室。充气室适于接收充气介质并且适于接触身体容器。还提供了包括阀装置和输送装置的输送系统。输送装置包括适于用充气介质填充阀装置的室的构件。还提供了制造阀装置的相关方法。

9. 发明授权

US08043302B2 Implant retrieval assembly and method for retrieving an implant 有权
标题翻译：植入物检索组件和用于检索植入物的方法
公开(公告)号：US08043302B2
公开(公告)日：2011-10-25
申请号：US11708235
申请日：2007-02-20
申请人： Jeffry S. Melsheimer , Thomas A. Osborne
发明人： Jeffry S. Melsheimer , Thomas A. Osborne
IPC分类号： A61B17/26
CPC分类号： A61B17/221 , A61B17/32056 , A61B17/3468 , A61B2017/0046 , A61B2017/00477 , A61B2017/2919
摘要： An implant retrieval frame for advancement of a retrieval device to snare an implant is disclosed. The frame comprises a first arm and a second arm. The first arm has a first handle end and a first pivot end. The second arm has a second handle end and a second pivot end. The second pivot end is connected to the first pivot end to define a pivot axis about which the first and second arm pivotally move. The frame further comprises a connector to which the retrieval device is attached. The connector is configured to cooperate with the first and second arms to translate pivotal movement of one of the first and second arms to linear movement of the retrieval device relative to the pivot point.
摘要翻译：公开了一种用于推进提取装置以圈套植入物的植入物检索框架。框架包括第一臂和第二臂。第一臂具有第一手柄端和第一枢转端。第二臂具有第二手柄端和第二枢转端。第二枢转端连接到第一枢转端以限定枢转轴线，第一和第二臂枢转运动。该框架还包括一个连接器，拾取装置附接到该连接器。连接器构造成与第一和第二臂配合以将第一和第二臂之一的枢转运动转换成相对于枢转点的线性运动。

10. 发明申请

US20100063577A1 METHOD OF IMPLANTING A PROSTHETIC VALVE 审中-公开
标题翻译：植入预制阀的方法
公开(公告)号：US20100063577A1
公开(公告)日：2010-03-11
申请号：US12621214
申请日：2009-11-18
申请人： Brian C. Case , Thomas A. Osborne , Jacob A. Flagle , Fred T. Parker
发明人： Brian C. Case , Thomas A. Osborne , Jacob A. Flagle , Fred T. Parker
IPC分类号： A61F2/06 , A61F2/82
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0008 , A61F2220/0016 , A61F2230/0067 , A61F2230/0078 , A61F2230/008 , A61F2250/0063
摘要： Methods of implanting a prosthetic valve in a body vessel are provided. A first expandable frame member is delivered to and deployed at a point of treatment in a body vessel. A second expandable frame member is delivered to the point of treatment. The second expandable frame member has an attached graft member that forms a valve adapted to permit fluid flow through the body vessel in a first direction and to substantially prevent fluid flow through the body vessel in a second, opposite direction. After deployment of the first expandable frame member, the second expandable frame member is deployed at the point of treatment such that the second frame member is positioned radially inward of the first frame member within said body vessel to form a prosthetic valve.
摘要翻译：提供了将人造瓣植入人体容器中的方法。第一可膨胀框架构件被输送到身体容器中并在其处处被部署。第二可膨胀框架构件被输送到处理点。第二可膨胀框架构件具有附接的移植构件，其形成适于允许流体沿第一方向流过身体容器的阀，并且基本上防止流体沿第二相反方向流过身体容器。在展开第一可膨胀框架构件之后，第二可膨胀框架构件在处理点处展开，使得第二框架构件位于所述主体容器内的第一框架构件的径向内侧以形成人造瓣膜。

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