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41. 发明申请

US20090326641A1 HELICAL OSTIUM SUPPORT FOR TREATING VASCULAR BIFURCATIONS 有权
标题翻译：用于治疗血管痉挛的螺旋OSTIUM支持
公开(公告)号：US20090326641A1
公开(公告)日：2009-12-31
申请号：US12553933
申请日：2009-09-03
申请人： H. Richard Davis , Aaron V. Kaplan
发明人： H. Richard Davis , Aaron V. Kaplan
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2/958 , A61F2002/821 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2002/9583 , A61F2220/0016 , A61F2250/0039 , A61M25/1002
摘要： A prosthesis is disclosed for placement across an ostium opening from a main body lumen to a branch body lumen. The prosthesis comprises a radially expansible support at one end, a circumferentially extending link at the other end and at least one spiral frond extending axially therebetween.
摘要翻译：公开了一种假体，用于穿过从主体内腔到分支体腔的口开口。假体包括在一端处的径向可膨胀的支撑件，在另一端处具有周向延伸的连接件以及在其间轴向延伸的至少一个螺旋形叶片。

42. 发明授权

US07481834B2 Stent for placement at luminal os 有权
标题翻译：支架置于腔内
公开(公告)号：US07481834B2
公开(公告)日：2009-01-27
申请号：US10807643
申请日：2004-03-23
申请人： Aaron V. Kaplan , Jaime Vargas
发明人： Aaron V. Kaplan , Jaime Vargas
IPC分类号： A61M29/00
CPC分类号： A61F2/91 , A61F2/852 , A61F2/856 , A61F2/915 , A61F2/954 , A61F2/958 , A61F2002/821 , A61F2002/8486 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2250/006
摘要： A prosthesis includes a radially expansible scaffold in at least two circumferential anchors extending from the scaffold. The prosthesis is placed across an os between a main body lumen and a branch lumen. The scaffold is expanded within the branch lumen and the circumferential anchors deformed outwardly to conform to the wall of the main body lumen. Optionally, a second prosthesis may be placed within the main body lumen after the first prosthesis has been deployed.
摘要翻译：假体包括在从支架延伸的至少两个周向锚固件中的可径向扩张的支架。假体被放置在主体腔和分支腔之间的口腔上。支架在分支腔内扩张，并且周向锚向外变形以符合主体腔的壁。任选地，在第一假体已经展开之后，第二假体可以放置在主体腔内。

43. 发明授权

US5855563A Method and apparatus for sequentially performing multiple intraluminal procedures 失效
标题翻译：顺序执行多个腔内手术的方法和装置
公开(公告)号：US5855563A
公开(公告)日：1999-01-05
申请号：US666778
申请日：1996-06-19
申请人： Aaron V. Kaplan , James R. Kermode , Enrique J. Klein
发明人： Aaron V. Kaplan , James R. Kermode , Enrique J. Klein
IPC分类号： A61M25/00 , A61B8/12 , A61F2/00 , A61F2/06 , A61F2/84 , A61M29/02 , A61M37/00 , A61M31/00
CPC分类号： A61M25/104 , A61B8/12 , A61B8/4488 , A61F2/958 , A61M29/02 , A61F2250/0067 , A61M2025/0057 , A61M2025/0063 , A61M2025/09183 , A61M2025/105 , A61M2025/1075 , A61M2025/1079 , A61M2025/1081 , A61M2025/1084 , A61M25/0054 , A61M25/1002 , A61M37/0092
摘要： Sleeve catheters having an interactive device near their distal ends are provided for introduction while disposed over conventional interventional and imaging catheters. Exemplary interactive devices on the sleeve catheters include ultrasonic imaging arrays, drug delivery lumens, and the like. The sleeve catheters are most commonly used with angioplasty catheters, stent placement catheters, atherectomy catheters, and the like.
摘要翻译：在其远端附近具有交互式装置的套管设置用于引入，同时设置在常规介入和成像导管之上。套管导管上的示例性交互设备包括超声波成像阵列，药物输送腔等。套管导管最常用于血管成形术导管，支架置入导管，粥样斑块切除术导管等。

44. 发明授权

US5776141A Method and apparatus for intraluminal prosthesis delivery 失效
标题翻译：腔内假体递送的方法和装置
公开(公告)号：US5776141A
公开(公告)日：1998-07-07
申请号：US704801
申请日：1996-08-26
申请人： Enrique J. Klein , Aaron V. Kaplan , Mark Clifford , Martin Overbeek-Bloem
发明人： Enrique J. Klein , Aaron V. Kaplan , Mark Clifford , Martin Overbeek-Bloem
IPC分类号： A61M25/00 , A61F2/00 , A61F2/82 , A61F2/958 , A61F11/00
CPC分类号： A61F2/958 , A61F2002/826 , A61F2002/9583 , A61F2250/0098
摘要： A catheter for use in combination with a balloon angioplasty catheter for delivering stents and other intraluminal prostheses comprises a tubular catheter body having a radially expansible portion. The stent is disposed over the radially expansible portion, and structure is provided for retaining the stent on the tubular body prior to deployment. The retaining structure may be active, i.e., requiring the user to retract retaining elements, such as axial members, sheaths, or the like. Alternatively, the retaining structure may be passive, wherein balloon expansion results in release of the prosthesis from the retaining structure. Particular methods for fluoroscopically positioning stents using such delivery catheters, for delivering two or more stents using such delivery catheters, and for overexpanding the ends of the stents for anchoring them in place, are also described.
摘要翻译：用于与用于输送支架和其他管腔内假体的气囊血管成形术导管组合使用的导管包括具有径向可膨胀部分的管状导管体。支架设置在径向可膨胀的部分上，并且提供结构用于在展开之前将支架保持在管状体上。保持结构可以是有效的，即要求用户缩回保持元件，例如轴向元件，护套等。或者，保持结构可以是被动的，其中球囊膨胀导致假体从保持结构的释放。还描述了使用这种输送导管的透视定位支架，用于使用这种输送导管输送两个或更多个支架以及用于过度扩张支架的端部以将其固定在适当位置的特定方法。

45. 发明授权

US5342348A Method and device for treating and enlarging body lumens 失效
标题翻译：用于治疗和扩大体腔的方法和装置
公开(公告)号：US5342348A
公开(公告)日：1994-08-30
申请号：US985382
申请日：1992-12-04
申请人： Aaron V. Kaplan
发明人： Aaron V. Kaplan
IPC分类号： A61F2/00 , A61F2/02 , A61F2/90 , A61K9/22 , A61L31/04 , A61L31/06 , A61L31/14 , A61L31/16
CPC分类号： A61F2/91 , A61L31/048 , A61L31/06 , A61L31/146 , A61L31/148 , A61L31/16 , A61F2/88 , A61F2/90 , A61F2210/0004 , A61F2230/0054 , A61F2250/0067 , A61F2250/0098 , A61L2300/602
摘要： The present invention relates generally to stents having delivery matrices which provide for the controlled release of bioactive substances. The delivery matrices comprise porous and erodible filaments, and multiple filaments may be employed in order to release different bioactive substances and/or the same bioactive substance at different delivery rates. The stents are particularly useful for preventing restenosis of dilated body lumens, such as blood vessels. Methods for preventing stenosis of dilated body lumens or locally delivering bioactive compounds to tissue are also provided.
摘要翻译：本发明一般涉及具有提供用于控制释放生物活性物质的递送基质的支架。递送基质包括多孔和可侵蚀长丝，并且可以使用多根细丝以便以不同的递送速率释放不同的生物活性物质和/或相同的生物活性物质。支架对于预防扩张体腔如血管的再狭窄特别有用。还提供了防止扩张体腔狭窄或局部递送生物活性化合物到组织的方法。

46. 发明授权

US5279565A Intravascular treatment apparatus and method 失效
标题翻译：血管内治疗装置及方法
公开(公告)号：US5279565A
公开(公告)日：1994-01-18
申请号：US12704
申请日：1993-02-03
申请人： Enrique J. Klein , Aaron V. Kaplan
发明人： Enrique J. Klein , Aaron V. Kaplan
IPC分类号： A61M29/00 , A61M31/00
CPC分类号： A61M25/007 , A61M29/02 , A61B2017/22084 , A61M2025/0057 , A61M2025/0096 , A61M2025/1095
摘要： An intravascular treatment apparatus provides means for infusing a treatment site with an agent and means for positioning the delivery interface against the treatment site which operate independently of one another. In a preferred embodiment, the apparatus includes a flexible body having a deflectable support frame at its distal end. A plurality of platforms, each comprising a plenum and a delivery interface, is coupled to the support frame. The platforms may be deployed radially from the body by deflecting the support frame using an actuator shaft extending through a passage in the body. The platforms are connected to a supply passage through the body. In this way, the apparatus may be positioned within a body lumen, usually an artery, with the platforms near a treatment site. By actuating the actuator shaft, the platforms are deployed against the treatment site. Independently of the platform deployment, a therapeutic agent may be supplied to the platforms and expelled through the delivery interface and into the treatment site to impregnate the treatment site.
摘要翻译：血管内治疗装置提供用于向治疗部位注入药剂的装置和用于将输送界面定位在相互独立操作的治疗部位上的装置。在优选实施例中，该装置包括柔性主体，其在其远端具有可偏转的支撑框架。多个平台，每个平台包括一个增压室和一个输送界面，它连接到支撑框架上。平台可以通过使用延伸穿过身体中的通道的致动器轴使支撑框架偏转而从身体径向展开。平台连接到穿过身体的供应通道。以这种方式，该装置可以位于体腔内，通常是动脉，其中平台靠近治疗部位。通过致动致动器轴，平台相对于处理部位展开。独立于平台部署，治疗剂可以供应到平台并通过输送界面排出并进入治疗部位以浸渍治疗部位。

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