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    • 41. 发明申请
    • Ocular Implants and Methods for Delivering Ocular Implants Into the Eye
    • 眼部植入物和将眼部植入物植入眼睛的方法
    • US20110009958A1
    • 2011-01-13
    • US12833863
    • 2010-07-09
    • John WardleAndrew T. SchieberKenneth M. Galt
    • John WardleAndrew T. SchieberKenneth M. Galt
    • A61F2/14
    • A61F9/0017A61F9/0026A61F9/00781
    • An ocular implant is provided. In some embodiments, the ocular implant includes a body that is curved about a longitudinal central axis and a distal body portion that defines a longitudinal channel including a channel opening. The implant is sized and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal. Methods for delivering ocular implants into Schlemm's canal are also provided. Some methods include covering openings in the ocular implant, advancing the implant into Schlemm's canal while at least some of the openings are covered, and uncovering the openings while the distal portion of the implant is disposed in Schlemm's canal.
    • 提供眼部植入物。 在一些实施例中,眼部植入物包括围绕纵向中心轴线弯曲的主体和限定包括通道开口的纵向通道的远侧主体部分。 植入物的尺寸和构造使得眼睛植入物呈现出当眼部植入物置于施莱姆氏管中时通道开口邻近施莱姆管道的主侧的取向。 还提供了将眼部植入物输送到施莱姆氏管中的方法。 一些方法包括覆盖眼部植入物中的开口,将植入物推进到施莱姆氏管中,同时至少一些开口被覆盖,并且在植入物的远端部分设置在施莱姆管中时露出开口。
    • 43. 发明申请
    • OCULAR IMPLANTS FOR DELIVERY INTO THE EYE
    • 用于输送到眼睛的OCULAR植入物
    • US20150366710A1
    • 2015-12-24
    • US14843563
    • 2015-09-02
    • Andrew T. SCHIEBERKenneth M. GALT
    • Andrew T. SCHIEBERKenneth M. GALT
    • A61F9/007A61F9/00
    • A61F9/00781A61F9/0017A61K9/0051
    • An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye. The implant includes a spine extending along a longitudinal axis of the implant, a plurality of curved supports extending from the spine, each support comprising a first end extending from a first location on a first side of the spine and a second end extending from a second location on a second side of the spine, the second location being proximal to the first location, so that each support forms a portion of a helix, the spine and supports defining a volume having a maximum width perpendicular to the longitudinal axis between 0.005 inches and 0.04 inches, the ocular implant being configured to bend preferentially in a preferential bending plane.
    • 适于至少部分地居住在眼睛的施莱姆氏管的一部分中的眼部植入物。 植入物包括沿着植入物的纵向轴线延伸的脊柱,从脊柱延伸的多个弯曲支撑件,每个支撑件包括从脊柱第一侧上的第一位置延伸的第一端部和从第二侧面延伸的第二端部 所述第二位置靠近所述第一位置,使得每个支撑件形成螺旋的一部分,所述脊柱和支撑件限定出垂直于所述纵向轴线的最大宽度在0.005英寸和 0.04英寸,眼部植入物构造成优先弯曲在优先弯曲平面中。
    • 47. 发明申请
    • Delivering Ocular Implants Into the Eye
    • 将眼部植入眼睛
    • US20130158462A1
    • 2013-06-20
    • US13330592
    • 2011-12-19
    • John WardleAndrew T. Schieber
    • John WardleAndrew T. Schieber
    • A61F9/007
    • A61F9/0026A61B17/3421A61B17/3468A61B2017/3454A61F9/0017A61F9/00781A61F2220/0033
    • A method of deploying an ocular implant into Schlemm's canal of an eye. The method includes the steps of inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula having a distal opening extending from the distal end and through a side wall; placing the distal opening of the cannula into fluid communication with Schlemm's canal; advancing the ocular implant distally through the cannula with a delivery tool engaged with the ocular implant, a proximal portion of the ocular implant engaging the delivery tool proximal to a distal portion of the delivery tool; and disengaging the ocular implant and the delivery tool when the proximal portion of the ocular implant reaches the cannula distal opening. The invention also includes a system for practicing the method.
    • 将眼部植入物部署到施莱姆的眼睛的运河中的方法。 该方法包括以下步骤:将套管的远端插入眼睛的角膜并插入眼睛的前房,该套管具有从远端延伸并穿过侧壁的远端开口; 放置套管的远端开口与施莱姆氏管流体连通; 通过具有与眼部植入物接合的输送工具将眼部植入物向远端推进通过套管,眼睛植入物的近端部分接近输送工具的远端部分; 并且当眼部植入物的近端部分到达套管远端开口时,使眼部植入物和递送工具脱离接合。 本发明还包括实施该方法的系统。
    • 50. 发明授权
    • Glaucoma treatment method
    • 青光眼治疗方法
    • US08282592B2
    • 2012-10-09
    • US12775266
    • 2010-05-06
    • Andrew T. SchieberCharles L. Euteneuer
    • Andrew T. SchieberCharles L. Euteneuer
    • A61M5/00A61F2/00A61F2/14
    • A61F9/00781A61F9/0017A61F2009/00891A61M27/002A61M2210/0612
    • An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye. In some embodiments the implant has a body extending in a curved volume whose longitudinal axis forms an arc of a circle, and a plurality of open areas and strut areas formed in the body, the open areas extending over more than 50% of a surface defining the curved volume, the strut areas surrounding the open areas, the body having a diameter of between 0.005 inches and 0.04 inches. The invention also provides a method of treating glaucoma including the steps of supporting tissue forming Schlemm's canal in an eye with an implant extending at least partially in the canal along an axial length within the canal; and contacting with the implant less than 50% of the tissue forming the canal along the axial length.
    • 适于至少部分地居住在眼睛的施莱姆氏管的一部分中的眼部植入物。 在一些实施例中,植入物具有在弯曲体积中延伸的主体,其纵向轴线形成圆弧,以及形成在主体中的多个开放区域和支柱区域,所述开放区域延伸超过表面的50%以上 弯曲的体积,围绕开放区域的支柱区域,主体具有在0.005英寸和0.04英寸之间的直径。 本发明还提供一种治疗青光眼的方法,包括以下步骤:在眼睛中支撑组织形成施莱姆氏管,其中植入物至少部分地沿着管内的轴向长度延伸至管内; 并且沿着轴向长度与植入物接触形成管的少于50%的组织。