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    • 34. 发明申请
    • SURFACE ENHANCED RAMAN SPECTROSCOPY CALIBRATION CURVE GENERATING SYSTEMS
    • 表面增强拉曼光谱校准曲线生成系统
    • US20130278928A1
    • 2013-10-24
    • US13449612
    • 2012-04-18
    • Devin Alexander MoureyJames William StasiakZhiyong Li
    • Devin Alexander MoureyJames William StasiakZhiyong Li
    • G01J3/44
    • G01N21/274G01N21/278G01N21/658
    • A surface enhanced Raman spectroscopy calibration curve generating system includes a SERS sensor, which includes a substrate and a plurality of sensing members formed on the substrate. Each of the sensing members includes a plurality of SERS signal amplifying structures. An inkjet dispensing device is to dispense different concentrations of a solution including a known analyte of interest onto the respective sensing members to form a concentration dependent array. A Raman spectrometer is to interrogate the concentration dependent array. A processor is operatively connected to each of the inkjet dispensing device and the Raman spectrometer. Computer-readable instructions are embedded on a non-transitory, tangible computer-readable medium and are executable by the processor. The computer-readable instructions are to automatically generate an intensity profile as a function of concentration for the concentration dependent array.
    • 表面增强拉曼光谱校准曲线生成系统包括SERS传感器,其包括衬底和形成在衬底上的多个感测构件。 每个感测构件包括多个SERS信号放大结构。 喷墨分配装置是将不同浓度的包括已知分析物的溶液分配到相应的感测构件上以形成浓度依赖阵列。 拉曼光谱仪是询问浓度依赖阵列。 处理器可操作地连接到每个喷墨分配装置和拉曼光谱仪。 计算机可读指令嵌入在非暂时有形的计算机可读介质中,并且可由处理器执行。 计算机可读指令是自动生成作为浓度依赖阵列的浓度的函数的强度分布。
    • 39. 发明授权
    • Sensing device and method producing a Raman signal
    • 产生拉曼信号的感测装置和方法
    • US08416406B2
    • 2013-04-09
    • US12914655
    • 2010-10-28
    • Michael Josef StukeShih-Yuan WangZhiyong Li
    • Michael Josef StukeShih-Yuan WangZhiyong Li
    • G01J3/44
    • B82Y15/00G01N21/65G01N21/658
    • A sensing device that produces a Raman signal includes micro-rods or nano-rods arranged on a substrate in a two-dimensional (2D) array, each of the rods having a length in a single row being substantially the same, with the rod length of each row being different from the rod length of each other row. Each row of rods has a respective resonant vibration frequency that varies from row to row. A source of vibration energy, operatively connected to the substrate, excites vibration in each of the rods such that a responding row resonates when an exciting frequency approaches the resonant vibration frequency of the responding row. A method includes exposing the 2D array to a light source and analyzing Raman scattering at each rod of the 2D array to render a Raman map.
    • 产生拉曼信号的感测装置包括以二维(2D)阵列布置在基底上的微棒或纳米棒,每根棒具有基本上相同的长度,其中棒长度 每行的距离与每隔一行的杆长度不同。 每排棒具有相应的谐振振动频率,其逐行变化。 可操作地连接到基板的振动能量源激发每个杆中的振动,使得当激励频率接近响应行的谐振振动频率时,响应行谐振。 一种方法包括将2D阵列暴露于光源并分析2D阵列的每个杆处的拉曼散射以呈现拉曼图。