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31. 发明授权

US06709891B2 Open-cavity semiconductor die package 失效
标题翻译：开放式半导体模具封装
公开(公告)号：US06709891B2
公开(公告)日：2004-03-23
申请号：US10231347
申请日：2002-08-30
申请人： Sanford W. Crane, Jr. , Lakshminarasimha Krishnapura , Yun Li
发明人： Sanford W. Crane, Jr. , Lakshminarasimha Krishnapura , Yun Li
IPC分类号： H01L2144
CPC分类号： H01L23/057 , H01L24/48 , H01L2224/05599 , H01L2224/48091 , H01L2224/48247 , H01L2224/85444 , H01L2924/00014 , H01L2924/01079 , H01L2924/16195 , H01L2924/181 , H01L2924/3025 , H01L2224/45015 , H01L2924/207 , H01L2224/45099 , H01L2924/00
摘要： A semiconductor die carrier includes a housing that defines a cavity for holding one or more semiconductor dies, electrically conductive leads, and a cover plate having an aperture formed therethrough. The housing includes insulative side walls and a end plate joined to the side walls. The side walls and the end plate may be molded together as a one-piece unit. One or more of the side walls includes openings for receiving the leads so that an internal lead section extends within the cavity and an external lead section extends from the side walls external of the housing. The side walls may include a recess for receiving the cover plate. The aperture in the cover plate allows a semiconductor die held in the housing to be exposed to the environment.
摘要翻译：半导体管芯载体包括限定用于保持一个或多个半导体管芯，导电引线和具有穿过其形成的孔的盖板的壳体。壳体包括绝缘侧壁和连接到侧壁的端板。侧壁和端板可以一体地模制在一起。一个或多个侧壁包括用于接收引线的开口，使得内部引线部分在空腔内延伸，并且外部引线部分从壳体外部的侧壁延伸。侧壁可以包括用于接收盖板的凹部。盖板中的孔允许保持在壳体中的半导体管芯暴露于环境中。

32. 发明授权

US08789364B2 Vacuum assist pump system 有权
标题翻译：真空辅助泵系统
公开(公告)号：US08789364B2
公开(公告)日：2014-07-29
申请号：US12296995
申请日：2006-04-14
申请人： Waikei Huen , Yun Li
发明人： Waikei Huen , Yun Li
IPC分类号： B60T13/46 , B60T17/02 , B60T13/52
CPC分类号： B60T13/52 , B60T17/02 , Y10T137/85986
摘要： A vacuum assist pump system includes a vacuum assist pump for assisting to a brake system by vacuum, wherein it includes a suction compensation pump connected with the vacuum assist pump. Advantageously, a vacuum compensation reservoir is arranged between the vacuum assist pump and the suction compensation pump. The vacuum compensation reservoir comprises a vacuity sensor for its internal vacuity and two interfaces. One of the two interfaces communicates to the suction compensation pump, the other communicates to the vacuum assist pump.
摘要翻译：真空辅助泵系统包括用于通过真空辅助制动系统的真空辅助泵，其中包括与真空辅助泵连接的吸力补偿泵。有利地，在真空辅助泵和吸力补偿泵之间设置真空补偿容器。真空补偿池包括一个真空传感器，用于其内部真空和两个界面。两个接口中的一个与吸力补偿泵通信，另一个与真空辅助泵通信。

33. 发明授权

US08696156B2 LED light bulb with light scattering optics structure 有权
标题翻译： LED灯泡与光散射光学结构
公开(公告)号：US08696156B2
公开(公告)日：2014-04-15
申请号：US13996806
申请日：2011-12-19
申请人： Chuan Yuan , Yun Li , Mo Shen , Zhigang Pei , Ye Liu
发明人： Chuan Yuan , Yun Li , Mo Shen , Zhigang Pei , Ye Liu
IPC分类号： F21V5/00 , F21V5/08
CPC分类号： F21V5/00 , F21K9/232 , F21K9/60 , F21V3/00 , F21V5/048 , F21V17/105 , F21Y2115/10
摘要： A LED light bulb (10, 110, 210) having at least one LED (30a-d, 230). Light output from the LED is directed toward an offset scattering optics structure (50, 150, 250) that intersects and scatters the light output. The LED may optionally be paired with a narrow beam optical piece (32a-d, 132a-d, 232) to focus and direct the light output of the LED toward the scattering optics structure. A mounting structure (40, 140, 240a, 240b) may support the scattering optics structure and offset the scattering optics structure from the LED.
摘要翻译：具有至少一个LED（30a-d，230）的LED灯泡（10,110,210）。来自LED的光输出指向与光输出相交和散射的偏移散射光学结构（50,150,250）。 LED可以可选地与窄光束光学片（32a-d，132a-d，232）配对，以将LED的光输出聚焦并引导到散射光学结构。安装结构（40,140,240a，240b）可以支撑散射光学结构并使散射光学结构偏离LED。

34. 发明申请

US20130285531A1 LED LIGHT BULB WITH LIGHT SCATTERING OPTICS STRUCTURE 有权
标题翻译： LED灯泡与光散射光学结构
公开(公告)号：US20130285531A1
公开(公告)日：2013-10-31
申请号：US13996806
申请日：2011-12-19
申请人： Chuan Yuan , Yun Li , Mo Shen , Zhigang Pei , Ye Liu
发明人： Chuan Yuan , Yun Li , Mo Shen , Zhigang Pei , Ye Liu
IPC分类号： F21V5/00
CPC分类号： F21V5/00 , F21K9/232 , F21K9/60 , F21V3/00 , F21V5/048 , F21V17/105 , F21Y2115/10
摘要： A LED light bulb (10, 110, 210) having at least one LED (30a-d, 230). Light output from the LED is directed toward an offset scattering optics structure (50, 150, 250) that intersects and scatters the light output. The LED may optionally be paired with a narrow beam optical piece (32a-d, 132a-d, 232) to focus and direct the light output of the LED toward the scattering optics structure. A mounting structure (40, 140, 240a, 240b) may support the scattering optics structure and offset the scattering optics structure from the LED.
摘要翻译：具有至少一个LED（30a-d，230）的LED灯泡（10,110,210）。来自LED的光输出指向与光输出相交和散射的偏移散射光学结构（50,150,250）。 LED可以可选地与窄光束光学片（32a-d，132a-d，232）配对，以将LED的光输出聚焦并引导到散射光学结构。安装结构（40,140,240a，240b）可以支撑散射光学结构并使散射光学结构偏离LED。

35. 发明授权

US08525954B2 Three-dimensional display article 有权
标题翻译：三维显示文章
公开(公告)号：US08525954B2
公开(公告)日：2013-09-03
申请号：US11768937
申请日：2007-06-27
申请人： Yun Li , Jie Liu , Gautam Parthasarathy , Anping Zhang , Gelu Comanescu
发明人： Yun Li , Jie Liu , Gautam Parthasarathy , Anping Zhang , Gelu Comanescu
IPC分类号： G02F1/1347
CPC分类号： H01L27/3209 , H01L27/3232 , H01L2251/5323 , H04N13/324 , H04N13/395
摘要： An article is provided in one embodiment of the invention. The article includes a display structure having a height, a width, and a thickness that define a volume. The display structure further includes components that emit light to generate a three-dimensional image within the volume. The display structure includes a stack. The stack includes at least one layer. The layer includes a substrate, the components that emit light and a controller. The components that emit light may each be secured to the substrate. The controller may be secured to the substrate. The controller may control the components that emit light to generate a three-dimensional image within the volume. The controller may be connected to two or more of the organic electronic devices. The components that emit light may include organic electronic devices. The components that emit light may include a light-emitting nano-wire device. The layer may include at least one sub-layer capable of emitting red light, at least one sub-layer capable of emitting blue light, and at least one sub-layer capable of emitting green light, and at least one layer that is capable of reversibly opacifying.
摘要翻译：在本发明的一个实施例中提供了一种物品。该物品包括具有限定体积的高度，宽度和厚度的显示结构。显示结构还包括发射光以在该体积内产生三维图像的组件。显示结构包括堆叠。堆叠包括至少一层。该层包括基底，发光的部件和控制器。发光的部件可以各自固定到基板上。控制器可以固定到基板。控制器可以控制发光的部件以在该体积内产生三维图像。控制器可以连接到两个或更多个有机电子设备。发光的部件可以包括有机电子器件。发光的部件可以包括发光纳米线器件。该层可以包括能够发射红光的至少一个子层，能够发射蓝光的至少一个子层和能够发出绿光的至少一个子层，以及至少一个能够发射绿光的子层可逆的不透明

36. 发明申请

US20130072554A1 Novel Method For Delivery and Use of Isothiocyanates For Prophylaxis and/or Therapy of Bladder Cancer 有权
标题翻译：用于递送和使用异硫氰酸酯进行膀胱癌预防和/或治疗的新方法
公开(公告)号：US20130072554A1
公开(公告)日：2013-03-21
申请号：US13609531
申请日：2012-09-11
申请人： Yuesheng Zhang , Arup Bhattacharya , Li Tang , Yun Li , Joseph D. Paonessa , Feng Geng , Yi Ding
发明人： Yuesheng Zhang , Arup Bhattacharya , Li Tang , Yun Li , Joseph D. Paonessa , Feng Geng , Yi Ding
IPC分类号： A61K31/26 , A61K36/31
CPC分类号： A61K31/26 , A61K36/31 , A61K2236/10
摘要： Provided is a composition that contains a mixture of broccoli seed and mustard seed. Before mixing the broccoli seed with the mustard seed, the broccoli seed is subjected to baking and a pressurized heat treatment. The broccoli seed is baked at a temperature of at least 200 degrees Fahrenheit for at least 60 minutes, and is subjected to a pressurized heat treatment of at least 200 degrees Fahrenheit at a pressure of at least 10 pounds/square inch for at least 5 minutes. Also provided is a method for therapy and/or prophylaxis of bladder cancer in an individual. The method entails administering orally to the individual a composition that contains an isothiocyanate (ITC) or a derivative thereof such that the administration inhibits the growth and/or recurrence of bladder cancer. Nutraceutical compositions are also provided.
摘要翻译：本发明提供一种含有西兰花籽和芥菜籽混合物的组合物。在将西兰花种子与芥菜种子混合之前，将花椰菜种子进行烘烤和加压热处理。将青花菜种子在至少200华氏度的温度下烘烤至少60分钟，并在至少10磅/平方英寸的压力下进行至少200华氏度的加压热处理至少5分钟。还提供了治疗和/或预防个体中膀胱癌的方法。该方法需要向个体口服含有异硫氰酸酯（ITC）或其衍生物的组合物，使得该给药抑制膀胱癌的生长和/或复发。还提供营养组合物。

37. 发明申请

US20110273900A1 OPTICAL ELEMENT AND LIGHT SOURCE COMPRISING THE SAME 有权
标题翻译：光学元件和包含该光学元件的光源
公开(公告)号：US20110273900A1
公开(公告)日：2011-11-10
申请号：US13143608
申请日：2010-01-05
申请人： Yun Li , Ye Liu
发明人： Yun Li , Ye Liu
IPC分类号： H01L33/02
CPC分类号： G02B19/0061 , F21K9/232 , F21K9/61 , F21V3/04 , F21Y2115/10 , G02B19/0019 , G02B19/0071
摘要： The present invention relates to an optical element including a light guide, into which light from one or more light-emitting diodes in a light unit arranged at one end of the light guide is injected, and a reflector arranged at the other end of the light guide capable of reflecting light incident on the reflector. The light guide further includes a prismatic surface comprising a plurality of prisms, each prism being arranged at an angle to an axial direction of the light guide, for guiding the light emitted from the light unit towards the output end of the light guide. The present invention also relates to a light source including an optical element according to the present invention, the light source being arranged for retrofitting into a luminaire employing an incandescent light source.
摘要翻译：光学元件技术领域本发明涉及一种光学元件，该光学元件包括导光体，其中布置在光导的一端处的光单元中的一个或多个发光二极管的光注入到该光学元件中，并且布置在该光的另一端的反射器引导件能够反射入射在反射器上的光。光导还包括棱镜表面，其包括多个棱镜，每个棱镜以与光导的轴向成一定角度的方式布置，用于将从光单元射出的光导向光导的输出端。本发明还涉及一种包括根据本发明的光学元件的光源，该光源被布置成用于改装为采用白炽光源的照明器。

38. 发明申请

US20090246785A1 NOVEL STEROID 5-ALPHA-REDUCTASE 有权
标题翻译：新型甾体5-ALPHA-REDUCTASE
公开(公告)号：US20090246785A1
公开(公告)日：2009-10-01
申请号：US12404590
申请日：2009-03-16
申请人： James L. Mohler , Mark Titus , Olga Kozyreva , O. Harris Ford, III , Elsbieta Kawinski , Yun Li
发明人： James L. Mohler , Mark Titus , Olga Kozyreva , O. Harris Ford, III , Elsbieta Kawinski , Yun Li
IPC分类号： C12Q1/68 , C12Q1/26
CPC分类号： C12Q1/26 , C07K2319/21 , C07K2319/40 , C12N9/001 , C12N2799/022 , G01N33/57434
摘要： The invention provides an isolated, novel steroid 5α-reductase enzyme termed SRD5AIII. The protein has an estimated molecular weight of 37 kDa and is capable of converting testosterone to dihydrotestosterone at a pH of about 7.0. Also provided is a method for identifying inhibitors of SRD5AIII by contacting SRD5AIII with a test compound and measuring the activity of the enzyme. A reduced activity relative to a control indicates that the test compound is an inhibitor of SRD5AIII. A method is also provided for detecting androgen stimulated prostate cancer or recurrent prostate cancer in an individual. The method comprises obtaining a prostate biopsy from an individual and determining the level of expression of SRD5AIII gene or protein relative to a normal control. An increased expression of SRD5AIII relative to the control is indicative of androgen stimulated prostate cancer or recurrent prostate cancer.
摘要翻译：本发明提供了一种分离的新型类固醇5α-还原酶，称为SRD5AIII。蛋白质具有37kDa的估计分子量，并且能够在约7.0的pH下将睾酮转化为二氢睾酮。还提供了通过使SRD5AIII与测试化合物接触并测量酶的活性来鉴定SRD5AIII的抑制剂的方法。相对于对照的降低的活性表明测试化合物是SRD5AIII的抑制剂。还提供了用于检测个体中激素刺激的前列腺癌或复发性前列腺癌的方法。该方法包括从个体获得前列腺活检，并确定相对于正常对照的SRD5AIII基因或蛋白质的表达水平。 SRD5AIII相对于对照的增加的表达指示雄激素刺激的前列腺癌或复发性前列腺癌。

39. 发明申请

US20090175889A1 HIV VACCINE 审中-公开
标题翻译：艾滋病疫苗
公开(公告)号：US20090175889A1
公开(公告)日：2009-07-09
申请号：US12201014
申请日：2008-08-29
申请人： Shiu-Lok Hu , Yun Li , Bradley Cleveland
发明人： Shiu-Lok Hu , Yun Li , Bradley Cleveland
IPC分类号： A61K39/21 , C12N15/11 , C12N7/00 , C07K14/00 , C12N5/06 , A61K31/7088
CPC分类号： A61K39/21 , A61K39/12 , A61K2039/5154 , A61K2039/53 , A61K2039/545 , A61K2039/55505 , C07K14/005 , C12N15/86 , C12N2710/24143 , C12N2740/15034 , C12N2740/16134 , C12N2740/16222
摘要： The invention provides a polynucleotide encoding an envelope protein comprising gp120 of human immunodeficiency virus-1 (HIV-1) having a mutation at amino acid residues 197-199 whereby a single N-linked glycan is removed. In a typical embodiment, the mutation replaces the asparagine (N) at residue 197 with another amino acid, such as glutamine (Q), creating an N197Q mutation. Because the N197 glycan is highly conserved among HIV-1 subtypes, this approach is applicable across HIV-1 isolates. The invention provides polypeptides, polynucleotides encoding the polypeptides, vectors, and recombinant viruses containing the polynucleotides, antigen-presenting cells (APCs) presenting the polypeptides, immune cells directed against HIV, and pharmaceutical compositions. The invention additionally provides methods, including methods for preventing and treating infection, for killing infected cells, for inhibiting viral replication, for enhancing secretion of antiviral and/or immunomodulatory lymphokines, and for enhancing production of neutralizing antibody.
摘要翻译：本发明提供了编码包含蛋白质的多核苷酸，其包含在氨基酸残基197-199上具有突变的人免疫缺陷病毒-1（HIV-1）的gp120，由此除去单个N-连接的聚糖。在典型的实施方案中，突变将残基197处的天冬酰胺（N）替换为另外的氨基酸，例如谷氨酰胺（Q），产生N197Q突变。因为N197聚糖在HIV-1亚型中是高度保守的，所以这种方法适用于HIV-1分离株。本发明提供了多肽，编码多肽的多核苷酸，载体和含有多核苷酸的重组病毒，呈递多肽的抗原呈递细胞（APC），针对HIV的免疫细胞和药物组合物。本发明还提供方法，包括用于预防和治疗感染的方法，用于杀死感染的细胞，用于抑制病毒复制，增强抗病毒和/或免疫调节淋巴因子的分泌，以及增强中和抗体的产生。

40. 发明授权

US07499151B2 Distributed Brillouin sensor system based on DFB lasers using offset locking 有权
标题翻译：基于使用偏移锁定的DFB激光器的分布式布里渊传感器系统
公开(公告)号：US07499151B2
公开(公告)日：2009-03-03
申请号：US11806986
申请日：2007-06-05
申请人： Xiaoyi Bao , Evgueni Ponomarev , Yun Li , Fabien Ravet , Lufan Zou , Omur M. Sezerman
发明人： Xiaoyi Bao , Evgueni Ponomarev , Yun Li , Fabien Ravet , Lufan Zou , Omur M. Sezerman
IPC分类号： G01L1/24
CPC分类号： G01K11/32 , G01K2011/322 , G01L1/242
摘要： A distributed Brillouin sensor system is provided. The system has two distributed feedback (DFB) lasers, which are locked at the Brillouin frequency of the optical fiber through offset locking method by coupler splitting into two parts. The split parts are sent to two photodiodes, the outputs of which are sent to a mixer. A PID controller means follows the mixer and a current controller follows the PID controller. The lasers have a wavelength of 1550 nm. The PID controller locks the frequency difference. An optical delay line is used to produce the frequency tuning of the two DFB lasers around the Brillouin frequency of the optical fibers. The lock-in amplifier is used to keep the DC level of the optical modulator at minimum.
摘要翻译：提供分布式布里渊传感器系统。该系统具有两个分布反馈（DFB）激光器，它们通过耦合器分为两部分的偏移锁定方式锁定在光纤的布里渊频率处。分离部分被发送到两个光电二极管，其输出被发送到混合器。 PID控制器装置跟随混频器，电流控制器跟随PID控制器。激光器的波长为1550nm。 PID控制器锁定频率差。使用光学延迟线来产生围绕光纤的布里渊频率的两个DFB激光器的频率调谐。锁定放大器用于将光调制器的直流电平保持在最小。

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