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31. 发明申请

US20070041498A1 SYSTEM AND METHOD OF REMOTELY DIRECTING RADIATION THERAPY TREATMENT 审中-公开
标题翻译：远程指导辐射治疗的系统和方法
公开(公告)号：US20070041498A1
公开(公告)日：2007-02-22
申请号：US11459113
申请日：2006-07-21
申请人： Gustavo Olivera , Thomas Mackie , Kenneth Ruchala , John Hughes , Paul Reckwerdt , Robert Cravens , Jeffrey Kapatoes , Eric Schnarr , Eric Schloesser , Weiguo Lu , David Murray
发明人： Gustavo Olivera , Thomas Mackie , Kenneth Ruchala , John Hughes , Paul Reckwerdt , Robert Cravens , Jeffrey Kapatoes , Eric Schnarr , Eric Schloesser , Weiguo Lu , David Murray
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61N5/103 , A61N2005/1074
摘要： Systems and methods for utilizing remote access to a radiation therapy treatment system. Remote access to the radiation therapy treatment system can assist in providing quality assurance processes, service and maintenance procedures, patient monitoring, and statistical analysis.
摘要翻译：利用远程访问放射治疗系统的系统和方法。远程访问放射治疗系统可以帮助提供质量保证过程，服务和维护程序，患者监测和统计分析。

32. 发明申请

US20070041495A1 METHOD OF AND SYSTEM FOR PREDICTING DOSE DELIVERY 有权
标题翻译：用于预测剂量递送的方法和系统
公开(公告)号：US20070041495A1
公开(公告)日：2007-02-22
申请号：US11459066
申请日：2006-07-21
申请人： Gustavo Olivera , Kenneth Ruchala , Eric Schnarr , Jeffrey Kapatoes , Weiguo Lu , Jason Haimerl , John Hughes , Thomas Mackie
发明人： Gustavo Olivera , Kenneth Ruchala , Eric Schnarr , Jeffrey Kapatoes , Weiguo Lu , Jason Haimerl , John Hughes , Thomas Mackie
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1038 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1069
摘要： A system and method of predicting a radiation dose to be delivered to a patient. The method includes the acts of generating a first image of at least a portion of the patient, defining a treatment plan for the patient, generating a second image of at least a portion of the patient while the patient is substantially in a treatment position, updating the patient profile with the second image, and predicting the radiation dose to be delivered to the patient based upon the patient profile and the treatment plan.
摘要翻译：一种预测要传送给患者的辐射剂量的系统和方法。该方法包括产生患者的至少一部分的第一图像的动作，为患者定义治疗计划，在患者基本处于治疗位置时产生患者的至少一部分的第二图像，更新患者轮廓与第二图像，并且基于患者概况和治疗计划预测要递送给患者的辐射剂量。

33. 发明申请

US20070088573A1 METHOD AND INTERFACE FOR ADAPTIVE RADIATION THERAPY 审中-公开
标题翻译：自适应放射治疗的方法和界面
公开(公告)号：US20070088573A1
公开(公告)日：2007-04-19
申请号：US11459052
申请日：2006-07-21
申请人： Kenneth Ruchala , Gustavo Olivera , Eric Schnarr , Jason Haimerl , Weiguo Lu , Quan Chen
发明人： Kenneth Ruchala , Gustavo Olivera , Eric Schnarr , Jason Haimerl , Weiguo Lu , Quan Chen
IPC分类号： G06Q10/00 , G06Q50/00
CPC分类号： A61N5/103 , A61N5/1038 , A61N5/1042 , A61N5/1065 , A61N2005/1074 , G06F19/3481 , G06Q50/22 , G16H40/63
摘要： A system and method for developing and analyzing radiation therapy treatment plans and a computer-generated user interface for presenting data relating to a radiation therapy treatment plan. The user interface includes a list of fractions identified in the treatment plan, data identifying delivery status of the fraction, and data identifying a processing status of the fraction. The system includes a computer processor, a data store connected to the computer processor and storing information relating to at least one fraction of a radiation therapy treatment plan, which fraction has been delivered to a patient as part of the implementation of the radiation therapy treatment plan, and software, stored in a computer readable medium accessible by the computer processor, the software being operable to automatically process the information relating to the at least one fraction.
摘要翻译：用于开发和分析放射治疗治疗计划的系统和方法以及用于呈现与放射治疗治疗计划有关的数据的计算机生成的用户界面。用户界面包括在治疗计划中识别的分数列表，识别分数的递送状态的数据以及识别分数的处理状态的数据。该系统包括计算机处理器，连接到计算机处理器的数据存储器，并且存储与辐射治疗计划的至少一部分有关的信息，该部分已经被递送给患者，作为放射治疗治疗计划的实施的一部分和软件，存储在计算机可读介质可由计算机处理器访问，所述软件可操作以自动处理与所述至少一个分数相关的信息。

34. 发明申请

US20070041499A1 METHOD AND SYSTEM FOR EVALUATING QUALITY ASSURANCE CRITERIA IN DELIVERY OF A TREATMENT PLAN 有权
标题翻译：评估治疗计划中提供质量保证标准的方法和系统
公开(公告)号：US20070041499A1
公开(公告)日：2007-02-22
申请号：US11459152
申请日：2006-07-21
申请人： Weiguo Lu , Gustavo Olivera , Jeffrey Kapatoes , Kenneth Ruchala , Eric Schnarr , John Hughes , Thomas Mackie , Paul Reckwerdt
发明人： Weiguo Lu , Gustavo Olivera , Jeffrey Kapatoes , Kenneth Ruchala , Eric Schnarr , John Hughes , Thomas Mackie , Paul Reckwerdt
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1075
摘要： System and method of evaluating quality assurance criteria related to the delivery of a radiation therapy treatment plan. The method includes the acts of acquiring image data of a patient, generating a treatment plan for the patient based at least in part on the image data, the treatment plan including a calculated radiation dose to be delivered to the patient, acquiring an on-line image of the patient in substantially a treatment position, delivering at least a portion of the calculated radiation dose to the patient, monitoring quality assurance criteria related to the delivery of the treatment plan, calculating the radiation dose received by the patient, and determining whether delivery of the treatment plan occurred as intended based on the quality assurance criteria and the radiation dose received by the patient.
摘要翻译：评估与放射治疗计划相关的质量保证标准的系统和方法。该方法包括获取患者的图像数据的动作，至少部分地基于图像数据生成针对患者的治疗计划，治疗计划包括计算出的要递送给患者的辐射剂量，获取在线将患者的图像基本上处于治疗位置，将计算的辐射剂量的至少一部分递送给患者，监测与治疗计划的递送相关的质量保证标准，计算患者接收的辐射剂量，以及确定是否递送的治疗计划根据质量保证标准和患者接受的放射剂量进行预期的发生。

35. 发明申请

US20070041494A1 METHOD AND SYSTEM FOR EVALUATING DELIVERED DOSE 有权
标题翻译：用于评估递送剂量的方法和系统
公开(公告)号：US20070041494A1
公开(公告)日：2007-02-22
申请号：US11459055
申请日：2006-07-21
申请人： Kenneth Ruchala , Gustavo Olivera , Weiguo Lu , Eric Schnarr , Jason Haimerl , Thomas Mackie , Jeffrey Kapatoes
发明人： Kenneth Ruchala , Gustavo Olivera , Weiguo Lu , Eric Schnarr , Jason Haimerl , Thomas Mackie , Jeffrey Kapatoes
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61N5/103 , A61N5/1042 , A61N5/1049 , A61N5/1065 , A61N5/1067 , A61N5/1069 , A61N5/107
摘要： A system and method of evaluating a radiation dose delivered to a patient receiving radiation therapy. The method includes the acts of generating a time-based series of patient images, collecting a time-based series of data indicating patient motion, and evaluating a radiation dose delivered to the patient based upon the time-based series of patient images and the time-based series of data.
摘要翻译：评估递送给接受放射治疗的患者的放射剂量的系统和方法。该方法包括产生基于时间的一系列患者图像的动作，收集指示患者运动的基于时间的一系列数据，以及基于基于时间的一系列患者图像和时间来评估递送给患者的辐射剂量的一系列数据。

36. 发明申请

US20070201613A1 SYSTEM AND METHOD OF DETECTING A BREATHING PHASE OF A PATIENT RECEIVING RADIATION THERAPY 有权
标题翻译：检测接受放射治疗的患者呼吸阶段的系统和方法
公开(公告)号：US20070201613A1
公开(公告)日：2007-08-30
申请号：US11459078
申请日：2006-07-21
申请人： Weiguo Lu , Kenneth Ruchala , Mingli Chen , Quan Chen , Gustavo Olivera
发明人： Weiguo Lu , Kenneth Ruchala , Mingli Chen , Quan Chen , Gustavo Olivera
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61N5/1042 , A61N5/1067 , A61N2005/1061
摘要： A system and method of detecting a breathing phase of a patient receiving radiation therapy is disclosed. The method, in one implementation, includes the acts of obtaining a plurality of patient images representing phases of a breathing cycle, delivering radiation to the patient, collecting transmission data of the patient during the delivering radiation, and comparing the transmission data to the plurality of patient images.
摘要翻译：公开了一种检测接受放射治疗的患者的呼吸阶段的系统和方法。该方法在一个实施方式中包括获取表示呼吸周期的相位的多个患者图像的动作，向患者传送辐射，在传送辐射期间收集患者的传输数据，以及将传输数据与多个病人图像。

37. 发明申请

US20050201516A1 Method for modification of radiotherapy treatment delivery 有权
标题翻译：放射治疗传递的修改方法
公开(公告)号：US20050201516A1
公开(公告)日：2005-09-15
申请号：US10506866
申请日：2003-03-06
申请人： Kenneth Ruchala , Gustavo Olivera , Jeffrey Kapatoes , Paul Reckwerdt , Weiguo Lu , John Hughes
发明人： Kenneth Ruchala , Gustavo Olivera , Jeffrey Kapatoes , Paul Reckwerdt , Weiguo Lu , John Hughes
IPC分类号： A61N20060101 , A61N1/00 , A61N5/10 , G06T1/00
CPC分类号： A61N5/103 , A61N5/1038 , A61N5/1065 , A61N5/1067 , A61N5/1069 , A61N2005/1061 , G06F19/00
摘要： The present invention provides a novel method of contoured-anatomy dose repositioning (CADR) as a means to automatically reposition a patient to better recover the planned dose distribution without reoptimize the treatment plan. Specifically, CADR utilizes planning CT images, the planned dose distribution, and on-line images for repositioning dose distribution on a given day. Contours are also placed upon the images using manual, automatic, template-based, or other techniques. CADR then optimizes the rigid-body repositioning of the patient so that the daily dose distribution closely matches the planned dose distribution. The present invention also provides a method of multiple-margin optimization with daily selection (MMODS) to improve radiation delivery without reoptimization. During the initial optimization procedure, plans are optimized for several margins of various contours (e.g., tight, medium, loose, etc.), or with different objectives (e.g., aggressive treatment, sensitive structure sparing, etc.). Similarly, if multiple patient image sets are available, plans can be optimized for the different anatomical layouts, either using current information, or accumulated information regarding the superposition of organ locations in the combination of images. A user can then choose in real time from a variety of optimized plans, generally with different margins, during the treatment process, and thereby compensate for a recognized change in size or position of the tumor or neighboring tissue.
摘要翻译：本发明提供了一种轮廓解剖学剂量重新定位（CADR）的新方法，作为自动重新定位患者的手段，以更好地恢复计划的剂量分布，而不重新优化治疗计划。具体来说，CADR利用计划的CT图像，计划的剂量分布和在线图像在给定的一天重新定位剂量分布。使用手动，自动，基于模板或其他技术的轮廓也被放置在图像上。然后，CADR优化患者的刚体重新定位，使得日剂量分布与计划的剂量分布密切相关。本发明还提供了一种利用日常选择（MMODS）进行多边距优化的方法，以改善辐射递送而不重新优化。在初始优化过程中，针对各种轮廓（例如紧密，中等，松散等）或不同目标（例如，积极的治疗，敏感的结构节省等）的几个边缘优化了计划。类似地，如果多个患者图像组可用，则针对不同的解剖结构布局可以优化计划，使用当前信息或关于图像组合中器官位置的叠加的累积信息。然后，用户可以在处理过程中从各种优化的计划（通常具有不同的边缘）实时地选择，从而补偿肿瘤或相邻组织的大小或位置的公认变化。

38. 发明授权

US06373970B1 Image registration using fourier phase matching 失效
标题翻译：图像配准使用傅立叶相位匹配
公开(公告)号：US06373970B1
公开(公告)日：2002-04-16
申请号：US09221729
申请日：1998-12-29
申请人： Fang Dong , Weiguo Lu
发明人： Fang Dong , Weiguo Lu
IPC分类号： G06K900
CPC分类号： G06K9/6203 , G06K9/32 , G06T7/37 , G06T2207/30004 , Y10S128/922 , Y10S128/923
摘要： A method and an apparatus for registering frames of imaging data using Fourier phase matching. Successive image frames of pixel data are processed using an image registration algorithm. Either image frames or the frames after edge detection are transformed into polar-logarithmic coordinates in the frequency domain and the phases of the Fourier transform of the resulting image representations, after inverse Fast Fourier transformation, are matched. The coordinates at the maximum phase difference are used to determine the scaling and rotation parameters needed for image frame registration. The frequency domain representation of one of the image frames is then scaled and rotated using an anti-aliasing algorithm in accordance with those parameters. The phase of the result is matched with the phase of the frequency domain representation of the other image frame to determine the translation parameters needed for image frame registration.
摘要翻译：一种使用傅立叶相位匹配来记录成像数据帧的方法和装置。使用图像配准算法处理像素数据的连续图像帧。将图像帧或边缘检测后的帧转换为频域中的极对数坐标，并且在快速傅里叶逆变换之后的所得图像表示的傅立叶变换的相位匹配。最大相位差处的坐标用于确定图像帧配准所需的缩放和旋转参数。然后使用根据这些参数的抗混叠算法对图像帧之一的频域表示进行缩放和旋转。结果的相位与其他图像帧的频域表示的相位匹配，以确定图像帧注册所需的平移参数。

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