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31. 发明授权

US08388653B2 T-type suture anchoring devices and methods of using same 有权
标题翻译： T型缝合线锚固装置及其使用方法
公开(公告)号：US08388653B2
公开(公告)日：2013-03-05
申请号：US11127513
申请日：2005-05-12
申请人： Rudolph H. Nobis , Frank Jankoski , Omar J. Vakharia , John A. Faux , Gregory J. Bakos , Duane A. Linenkugel , Christopher Paul Swain
发明人： Rudolph H. Nobis , Frank Jankoski , Omar J. Vakharia , John A. Faux , Gregory J. Bakos , Duane A. Linenkugel , Christopher Paul Swain
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0487 , A61B17/06166 , A61B2017/0409 , A61B2017/0417 , A61B2017/0445 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052
摘要： Suture anchoring devices are disclosed, including a T-tag anchoring device that is suitably small enough to fit into the hollow tip of a needle and, furthermore, provide protection to the suture against being cut or otherwise damaged by the sharp edge of the needle tip. One disclosed device includes a slot for providing a pivot point between the suture and the body when deployed, which can be employed to form a T-tag.
摘要翻译：公开了缝合线锚定装置，其包括T形锚定装置，其适当地足够小以适合于针的中空尖端，并且此外，为缝合线提供保护以免被针尖的尖锐边缘切割或以其它方式损伤。一个公开的装置包括用于在展开时在缝合线和主体之间提供枢轴点的槽，其可用于形成T形标签。

32. 发明授权

US08211114B2 Medical instrument having a medical snare 有权
标题翻译：具有医疗圈套的医疗器械
公开(公告)号：US08211114B2
公开(公告)日：2012-07-03
申请号：US11409732
申请日：2006-04-24
申请人： Rudolph H. Nobis , Ifung Lu
发明人： Rudolph H. Nobis , Ifung Lu
IPC分类号： A61B17/24 , A61B17/26
CPC分类号： A61B17/32056 , A61B2017/00867 , A61B2018/1407
摘要： A medical instrument including a resiliently flexible first elongate member and a resiliently flexible second elongate member. The first elongate member has a first proximal end portion and a first distal portion. The second elongate member has a second proximal end portion and a second distal portion, wherein the second distal portion is attached to the first distal portion, and wherein the attached first and second distal portions define a distal-loop medical snare which is insertable within a patient. In a first example, the first proximal end portion is lengthwise translatable with respect to the second proximal end portion to articulate the medical snare. In the same or a second example, the first proximal end portion is rotatable about its centerline to articulate the medical snare.
摘要翻译：一种医疗器械，包括弹性柔性的第一细长构件和弹性柔性的第二细长构件。第一细长构件具有第一近端部分和第一远端部分。所述第二细长构件具有第二近端部分和第二远端部分，其中所述第二远端部分附接到所述第一远端部分，并且其中所述附接的第一远端部分和所述第二远端部分限定远端环形医疗圈套，患者。在第一示例中，第一近端部分可相对于第二近端部分纵向平移，以便铰接医疗圈套。在相同或第二示例中，第一近端部分可围绕其中心线旋转以铰接医疗圈套。

33. 发明申请

US20110295151A1 Enteroendocrine Manipulation for Metabolic Effect 审中-公开
标题翻译：肠内分泌操作代谢作用
公开(公告)号：US20110295151A1
公开(公告)日：2011-12-01
申请号：US13104282
申请日：2011-05-10
申请人： Gregory J. Bakos , Edward G. Chekan , Denzel Z. Herrera-Davis , Jason L. Harris , Gary L. Long , Rudolph H. Nobis , Mark S. Ortiz , Mark D. Overmyer , David N. Plescia , Randy J. Seeley , William B. Weisenburgh, II , Tamara S. Vetro Widenhouse , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Gregory J. Bakos , Edward G. Chekan , Denzel Z. Herrera-Davis , Jason L. Harris , Gary L. Long , Rudolph H. Nobis , Mark S. Ortiz , Mark D. Overmyer , David N. Plescia , Randy J. Seeley , William B. Weisenburgh, II , Tamara S. Vetro Widenhouse , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61M37/00 , A61P3/00 , A61K9/00 , A61F2/04 , A61K49/00 , A61P3/04 , A61B10/02 , A61M5/00 , A61K35/55 , A61K9/20
CPC分类号： C12N5/0679 , A61K35/12 , A61K35/38 , A61L27/14 , A61L27/3882 , A61L27/58 , A61L31/04 , A61L31/148 , A61L31/16 , A61L2300/64
摘要： L-cells may be introduced in the gastrointestinal tract. L-cells are used in the digestive process to produce a more efficient and lasting means of regulating feelings of satiation in a patient. Desired metabolic effects may be achieved by manipulating L-cells via delivery sites, frequency of delivery, or type of biological substance delivered.
摘要翻译： L细胞可能被引入胃肠道。 L细胞用于消化过程，以产生更有效和持久的调节患者饱腹感的手段。所需的代谢作用可以通过经由递送部位操纵L细胞，递送频率或递送的生物物质的类型来实现。

34. 发明授权

US07833223B2 Tri-bending sphinctertome 有权
标题翻译：三弯括约肌切开术
公开(公告)号：US07833223B2
公开(公告)日：2010-11-16
申请号：US11381006
申请日：2006-05-01
申请人： Omar Vakharia , Ifung Lu , Rudolph H. Nobis , Christopher Paul Swain
发明人： Omar Vakharia , Ifung Lu , Rudolph H. Nobis , Christopher Paul Swain
IPC分类号： A61B18/14 , A61B17/32
CPC分类号： A61B18/1492 , A61B17/320016 , A61B2017/003 , A61B2018/00553 , A61B2018/00601 , A61B2018/144 , A61B2018/1467
摘要： Disclosed herein are devices and methods for forming multidirectional cuts in tissue. The tissue cutting devices disclosed herein generally include a flexible elongate member with at least first, second, and third wires that are at least partially constrained within or along a portion of the member. A distal portion of the wires is anchored on or within a portion of the elongate member. When tension is applied to at least one of the wires, such as by an actuator at a proximal end of the device, the elongate member bows while an unconstrained portion of the wire becomes exposed relative to the adjacent portion of the elongate member, assuming a tissue-cutting configuration.
摘要翻译：本文公开了用于在组织中形成多向切割的装置和方法。本文公开的组织切割装置通常包括柔性细长构件，其具有至少部分地限制在构件的一部分内或沿着构件的一部分的至少第一，第二和第三导线。电线的远端部分锚定在细长构件的一部分上或内部。当张紧被施加到至少一根电线时，例如通过设备近端处的致动器，细长构件弯曲，同时线的非约束部分相对于细长构件的相邻部分露出，假定组织切割配置。

35. 发明授权

US4892244A Surgical stapler cartridge lockout device 失效
标题翻译：手术吻合器卡锁装置
公开(公告)号：US4892244A
公开(公告)日：1990-01-09
申请号：US267907
申请日：1988-11-07
申请人： William D. Fox , Rudolph H. Nobis , Richard P. Nuchols , Mark S. Zeiner
发明人： William D. Fox , Rudolph H. Nobis , Richard P. Nuchols , Mark S. Zeiner
IPC分类号： A61B17/068 , A61B17/072 , A61B19/00 , B25C5/16
CPC分类号： B25C5/1686 , A61B17/068 , A61B17/07207 , A61B2017/07214 , A61B2017/2945 , A61B2090/0814
摘要： A lockout mechanism actuable upon the firing of staples in a surgical staple cartridge such that the lockout mechanism prevents the refiring of the spent staple cartridge when that cartridge remains loaded within the surgical stapler. In addition, the lockout mechanism will prevent reloading of a spent staple cartridge within a surgical stapler after the spent staple cartridge has been removed from the surgical stapler.

36. 发明授权

US08062306B2 Manually articulating devices 有权
标题翻译：手动铰接装置
公开(公告)号：US08062306B2
公开(公告)日：2011-11-22
申请号：US11610803
申请日：2006-12-14
申请人： Rudolph H. Nobis , Anil K. Nalagatla , Sean P. Conlon
发明人： Rudolph H. Nobis , Anil K. Nalagatla , Sean P. Conlon
IPC分类号： A61B17/32
CPC分类号： A61B17/29 , A61B10/06 , A61B17/2909 , A61B2017/2927 , A61B2017/2929 , A61B2017/2939
摘要： Methods and devices are provided for controlling movement of a working end of a surgical device, and in particular for performing various surgical procedures using an instrument having an end effector that can be articulated relative to an elongate shaft of the device. In certain embodiments, the end effector can also optionally rotate relative to the elongate shaft of the device, and/or the shaft can rotate relative to a handle of the device.
摘要翻译：提供了用于控制手术装置的工作端的移动的方法和装置，特别是用于使用具有可相对于装置的细长轴铰接的端部执行器的器具执行各种外科手术程序。在某些实施例中，末端执行器还可以相对于装置的细长轴可选地旋转，和/或轴可相对于装置的手柄旋转。

37. 发明授权

US08021363B2 Dual-bend sphinctertome 有权
标题翻译：双弯括约肌切开术
公开(公告)号：US08021363B2
公开(公告)日：2011-09-20
申请号：US11741198
申请日：2007-04-27
申请人： Omar J. Vakharia , Rudolph H. Nobis , Christopher Paul Swain , Charles Alexander Mosse , Keiichi Ikeda
发明人： Omar J. Vakharia , Rudolph H. Nobis , Christopher Paul Swain , Charles Alexander Mosse , Keiichi Ikeda
IPC分类号： A61B18/14 , A61B17/32
CPC分类号： A61B18/1492 , A61B17/320016 , A61B17/32056 , A61B2017/00278 , A61B2017/003 , A61B2018/1407 , A61B2018/144 , A61B2018/1467 , A61B2018/1475
摘要： Disclosed herein are devices and methods for forming multidirectional cuts in tissue. The tissue cutting devices disclosed herein generally include a flexible elongate member with at least first and second wires that are at least partially constrained within or along a portion of the member. A distal portion of the wires is anchored on or within a portion of the elongate member. When tension is applied to one of the wires, such as by an actuator at a proximal end of the device, the elongate member bows while an unconstrained portion of the wire becomes exposed relative to the adjacent portion of the elongate member, assuming a tissue-cutting configuration.
摘要翻译：本文公开了用于在组织中形成多向切割的装置和方法。本文公开的组织切割装置通常包括柔性细长构件，其具有至少部分地限制在构件的一部分内或沿构件的一部分的至少第一和第二导线。电线的远端部分锚定在细长构件的一部分上或内部。当例如通过设备近端的致动器将张力施加到一个电线上时，细长构件弯曲，同时线的非约束部分相对于细长构件的相邻部分露出，假设组织 - 切割配置。

38. 发明授权

US07867228B2 Apparatus and method for performing an endoscopic mucosal resection 有权
标题翻译：用于进行内窥镜粘膜切除术的装置和方法
公开(公告)号：US07867228B2
公开(公告)日：2011-01-11
申请号：US11414619
申请日：2006-04-28
申请人： Rudolph H. Nobis , Ifung Lu
发明人： Rudolph H. Nobis , Ifung Lu
IPC分类号： A61B18/18
CPC分类号： A61B17/320016 , A61B18/1445 , A61B2017/00269 , A61B2017/00353 , A61B2017/2927 , A61B2017/2939 , A61B2017/2945 , A61B2017/32004 , A61B2017/320044 , A61B2018/00482 , A61B2018/1432 , A61B2018/144
摘要： A surgical device including an elongated shaft having a distal end and a proximal end, an arm pivotally connected to the distal end and moveable through a dissection plane, and a cutting element disposed on the arm and adapted to move from an un-deployed configuration to a deployed configuration, wherein the cutting element is generally aligned with the dissection plane when in the un-deployed configuration and at least partially transverse with respect to the dissection plane when in the deployed configuration.
摘要翻译：一种手术装置，包括具有远端和近端的细长轴，枢转地连接到远端并可移动穿过解剖平面的臂，以及设置在臂上的切割元件，并且适于从未展开的构型移动到部署构型，其中当处于展开构型时，切割元件大致与解剖平面对准，当处于未展开构型时，并且当处于展开构型时相对于解剖平面至少部分横向。

39. 发明申请

US20100280327A1 METHODS AND DEVICES FOR PROVIDING ACCESS THROUGH TISSUE TO A SURGICAL SITE 审中-公开
标题翻译：用于向外科手术组织提供通路的方法和装置
公开(公告)号：US20100280327A1
公开(公告)日：2010-11-04
申请号：US12435075
申请日：2009-05-04
申请人： Rudolph H. Nobis , Andrew M. Zwolinski
发明人： Rudolph H. Nobis , Andrew M. Zwolinski
IPC分类号： A61B1/32
CPC分类号： A61B17/3423 , A61B1/32 , A61B17/0293 , A61B2017/3443 , A61B2017/3466
摘要： Methods and devices are provided for providing access through tissue to a surgical site. In one embodiment, a surgical access device can be configured to move between a first, expanded configuration, and a second, compressed configuration. As the device moves from the first configuration to the second configuration, a longitudinal length of the device can decrease, thereby allowing the device to be securely positioned in tissue and reducing a distance that the device extends into a body cavity.
摘要翻译：提供了用于提供通过组织进入外科手术部位的方法和装置。在一个实施例中，手术进入装置可被配置成在第一扩张配置和第二压缩配置之间移动。当设备从第一配置移动到第二配置时，设备的纵向长度可以减小，从而允许设备被牢固地定位在组织中并且减小设备延伸到体腔中的距离。

40. 发明申请

US20090299143A1 ACTUATING AND ARTICULATING SURGICAL DEVICE 有权
标题翻译：执行和治疗手术设备
公开(公告)号：US20090299143A1
公开(公告)日：2009-12-03
申请号：US12129880
申请日：2008-05-30
申请人： Sean P. Conlon , Rudolph H. Nobis , Frederick Q. Johnson , Steven P. Woodard , Ruth E. Costa
发明人： Sean P. Conlon , Rudolph H. Nobis , Frederick Q. Johnson , Steven P. Woodard , Ruth E. Costa
IPC分类号： A61B1/00
CPC分类号： A61B17/29 , A61B10/04 , A61B10/06 , A61B18/14 , A61B18/1482 , A61B2017/003 , A61B2017/00424 , A61B2017/00433 , A61B2017/00477 , A61B2017/2905 , A61B2017/2911 , A61B2017/2927 , A61B2017/2929 , A61B2017/2946 , A61B2018/1407 , A61B2018/141 , A61B2034/305
摘要： Methods and devices are provided for controlling movement of a working end of a surgical device, and in particular for performing various surgical procedures using an instrument having an end effector that can be articulated relative to an elongate shaft of the device. A decoupling member can isolate the actuation of the end effector from the articulation of the end effector. In certain embodiments, the end effector can also optionally rotate relative to the elongate shaft of the device, and/or the shaft can rotate relative to a handle of the device.
摘要翻译：提供了用于控制手术装置的工作端的移动的方法和装置，特别是用于使用具有可相对于装置的细长轴铰接的端部执行器的器具执行各种外科手术程序。解耦构件可以将端部执行器的致动与末端执行器的铰接隔离。在某些实施例中，末端执行器还可以相对于装置的细长轴可选地旋转，和/或轴可相对于装置的手柄旋转。

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