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    • 5. 发明授权
    • Electroporation ablation apparatus, system, and method
    • 电穿孔消融装置,系统及方法
    • US08449538B2
    • 2013-05-28
    • US12694452
    • 2010-01-27
    • Gary L. Long
    • Gary L. Long
    • A61B18/14
    • A61B18/1492A61B1/018A61B1/04A61B1/06A61B18/1482A61B2018/00482A61B2018/00577A61B2018/00613A61N1/306A61N1/327
    • A surgical instrument, such as an endoscopic or laparoscopic instrument, includes an ablation device. The ablation device includes an elongate relatively flexible member having a proximal end and a distal end, the flexible member includes at least a first working channel. A first and second electrode extends from a working channel at the distal end of the flexible member. The first and second electrodes are adapted to be endoscopically located in a tissue treatment region. The first and second electrodes are adapted to couple to an electrical waveform generator to receive an irreversible electroporation electrical waveform sufficient to ablate tissue located between the first and second electrodes. The waveform parameters of the irreversible electroporation electrical waveform are determined based on image information received from the tissue treatment region.
    • 诸如内窥镜或腹腔镜仪器的手术器械包括消融装置。 消融装置包括具有近端和远端的细长相对柔性的构件,所述柔性构件至少包括第一工作通道。 第一和第二电极从柔性构件的远端处的工作通道延伸。 第一和第二电极适于内窥镜地位于组织治疗区域中。 第一和第二电极适于耦合到电波形发生器以接收足以消融位于第一和第二电极之间的组织的不可逆电穿孔电波形。 基于从组织处理区域接收的图像信息确定不可逆电穿孔电波形的波形参数。
    • 6. 发明授权
    • Electroporation ablation apparatus, system, and method
    • 电穿孔消融装置,系统及方法
    • US08425505B2
    • 2013-04-23
    • US13218221
    • 2011-08-25
    • Gary L. Long
    • Gary L. Long
    • A61B18/04A61B1/00
    • A61B18/1492A61B1/018A61B1/04A61B1/06A61B18/1482A61B2018/00482A61B2018/00577A61B2018/00613A61N1/306A61N1/327
    • A surgical instrument, such as an endoscopic or laparoscopic instrument, includes an ablation device. The ablation device includes an elongate member having first and second channels. First and second probes are disposed within the respective first and second channels. The first and second probes each define a central axis. The first and second probes each have substantially straight distal ends protruding from the distal ends of the respective first and second channels. The substantially straight distal ends define an outer surface. First and second electrodes are attached to a portion of the outer surface of the substantially straight distal ends of the respective first and second probes. The first and second electrodes are positioned in juxtaposed relationship with the central axis of the first and second probes. A distance between the first and second electrodes is adjustable by rotating at least one of the first and second probes about the respective central axis of the at least one of the first and second probes.
    • 诸如内窥镜或腹腔镜仪器的手术器械包括消融装置。 消融装置包括具有第一和第二通道的细长构件。 第一和第二探针设置在相应的第一和第二通道内。 第一和第二探针均限定中心轴。 第一和第二探头各自具有从相应的第一和第二通道的远端突出的基本上直的远端。 基本上直的远端限定外表面。 第一和第二电极附接到相应的第一和第二探针的基本上直的远端的外表面的一部分。 第一和第二电极与第一和第二探针的中心轴线并置放置。 第一和第二电极之间的距离可通过使第一和第二探针中的至少一个围绕第一和第二探针中的至少一个探针的相应中心轴旋转来调节。