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1. 发明申请

US20190223936A1 INDICATING SYSTEM AND METHOD FOR ELECTROSURGICAL INSTRUMENT 审中-公开
公开(公告)号：US20190223936A1
公开(公告)日：2019-07-25
申请号：US16336799
申请日：2017-09-26
申请人： Matthew Otten , Gary L. Long , Jeffrey A. Benz , Richard L. Grant
发明人： Matthew Otten , Gary L. Long , Jeffrey A. Benz , Richard L. Grant
IPC分类号： A61B18/12 , A61B18/14
摘要： Systems and associated methods for sensing and indicating when a wide range of tissue is adequately cauterized and/or sealed by an electrosurgical instrument. The system indirectly monitors the current flowing through the tissue and determines the adequacy of tissue cauterization or sealing of vessel(s) by monitoring when the current is stable or nearly stable (i.e. when the current is constant). The system may also indicate a predetermined time that current is applied through the tissue and control the flow of energy through the tissue.

2. 发明授权

US10314649B2 Flexible expandable electrode and method of intraluminal delivery of pulsed power 有权
公开(公告)号：US10314649B2
公开(公告)日：2019-06-11
申请号：US13565307
申请日：2012-08-02
申请人： Gregory J. Bakos , David N. Plescia , Gary L. Long , Peter K. Shires
发明人： Gregory J. Bakos , David N. Plescia , Gary L. Long , Peter K. Shires
IPC分类号： A61B18/18 , A61B18/14 , A61B17/00 , A61B18/00
摘要： A surgical instrument, such as an electrical ablation device, includes an elongate member having therealong disposed a first electrode extending along an axis. A first expandable portion extends along the axis and defines a first perimeter of the first electrode and has an associated first diameter with respect to the axis. The first expandable portion includes a first framework selectively expandable to transition the first expandable portion from a contracted state to an expanded state. The first framework is selectively contractible to transition the first expandable portion from the expanded state to the contracted state. When the first framework is expanded, the first diameter is expanded and the first expandable portion is transitioned from the contracted state to the expanded state. When the first framework is contracted, the first diameter is contracted and the first expandable portion is transitioned from the expanded state to the contracted state.

3. 发明授权

US09078662B2 Endoscopic cap electrode and method for using the same 有权
标题翻译：内镜帽电极及其使用方法
公开(公告)号：US09078662B2
公开(公告)日：2015-07-14
申请号：US13540850
申请日：2012-07-03
申请人： Gregory J. Bakos , Peter K. Shires , Gary L. Long
发明人： Gregory J. Bakos , Peter K. Shires , Gary L. Long
IPC分类号： A61B18/14 , H02J17/00 , A61B18/00 , A61B18/16
CPC分类号： A61B18/1477 , A61B2018/00196 , A61B2018/00577 , A61B2018/00613 , A61B2018/00982 , A61B2018/1425 , A61B2018/162 , A61B2217/005 , A61B2218/007 , H02J17/00 , H02J50/10
摘要： An apparatus for treating tissue in a tissue treatment region. The apparatus can comprise an electrode ring having an interior perimeter and an electrode probe having a proximal end and a distal end. The distal end of the electrode probe can be structured to axially translate relative to the interior perimeter of the electrode ring. The electrode ring and the electrode probe can be operably structured to conduct current therebetween when at least one of the electrode ring and the electrode probe is energized by an energy source. Further, the energy source can be a Radio Frequency (RF) energy source, a pulsed energy source, an irreversible electroporation energy source, or a pulsed irreversible electroporation energy source. A current from the energy source can be selected to non-thermally ablate tissue in the tissue treatment region.
摘要翻译：一种用于处理组织处理区域中的组织的装置。该装置可以包括具有内周边的电极环和具有近端和远端的电极探针。电极探针的远端可被构造为相对于电极环的内部周边轴向平移。当电极环和电极探针中的至少一个被能量源激励时，电极环和电极探针可以可操作地构造成在其间传导电流。此外，能源可以是射频（RF）能量源，脉冲能量源，不可逆电穿孔能源或脉冲不可逆电穿孔能源。可以选择来自能量源的电流以在组织处理区域中非热消融组织。

4. 发明申请

US20140052216A1 METHODS FOR PROMOTING WOUND HEALING 审中-公开
标题翻译：促进伤口愈合的方法
公开(公告)号：US20140052216A1
公开(公告)日：2014-02-20
申请号：US13586439
申请日：2012-08-15
申请人： Gary L. Long , Gregory J. Bakos , David N. Plescia , Peter K. Shires
发明人： Gary L. Long , Gregory J. Bakos , David N. Plescia , Peter K. Shires
IPC分类号： A61N1/00
CPC分类号： A61N1/0468 , A61B5/01 , A61B17/064 , A61B18/1477 , A61B2017/00084 , A61B2017/00154 , A61B2018/00613 , A61B2018/00642 , A61B2018/00791 , A61N1/326 , A61N1/327
摘要： A method for promoting wound healing at a wound site includes subjecting the wound site to electrical pulses to promote wound healing during at least one of the stages of wound healing. The method may further include closing the wound site by sutures or staples prior to and or after applying the electrical pulses that promote wound healing.
摘要翻译：用于促进伤口部位的伤口愈合的方法包括在伤口愈合的至少一个阶段中对创伤部位进行电脉冲以促进伤口愈合。该方法可以进一步包括在施加促进伤口愈合的电脉冲之前和之后通过缝合线或缝钉来闭合伤口部位。

5. 发明授权

US08449538B2 Electroporation ablation apparatus, system, and method 有权
标题翻译：电穿孔消融装置，系统及方法
公开(公告)号：US08449538B2
公开(公告)日：2013-05-28
申请号：US12694452
申请日：2010-01-27
申请人： Gary L. Long
发明人： Gary L. Long
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B1/018 , A61B1/04 , A61B1/06 , A61B18/1482 , A61B2018/00482 , A61B2018/00577 , A61B2018/00613 , A61N1/306 , A61N1/327
摘要： A surgical instrument, such as an endoscopic or laparoscopic instrument, includes an ablation device. The ablation device includes an elongate relatively flexible member having a proximal end and a distal end, the flexible member includes at least a first working channel. A first and second electrode extends from a working channel at the distal end of the flexible member. The first and second electrodes are adapted to be endoscopically located in a tissue treatment region. The first and second electrodes are adapted to couple to an electrical waveform generator to receive an irreversible electroporation electrical waveform sufficient to ablate tissue located between the first and second electrodes. The waveform parameters of the irreversible electroporation electrical waveform are determined based on image information received from the tissue treatment region.
摘要翻译：诸如内窥镜或腹腔镜仪器的手术器械包括消融装置。消融装置包括具有近端和远端的细长相对柔性的构件，所述柔性构件至少包括第一工作通道。第一和第二电极从柔性构件的远端处的工作通道延伸。第一和第二电极适于内窥镜地位于组织治疗区域中。第一和第二电极适于耦合到电波形发生器以接收足以消融位于第一和第二电极之间的组织的不可逆电穿孔电波形。基于从组织处理区域接收的图像信息确定不可逆电穿孔电波形的波形参数。

6. 发明授权

US08425505B2 Electroporation ablation apparatus, system, and method 有权
标题翻译：电穿孔消融装置，系统及方法
公开(公告)号：US08425505B2
公开(公告)日：2013-04-23
申请号：US13218221
申请日：2011-08-25
申请人： Gary L. Long
发明人： Gary L. Long
IPC分类号： A61B18/04 , A61B1/00
CPC分类号： A61B18/1492 , A61B1/018 , A61B1/04 , A61B1/06 , A61B18/1482 , A61B2018/00482 , A61B2018/00577 , A61B2018/00613 , A61N1/306 , A61N1/327
摘要： A surgical instrument, such as an endoscopic or laparoscopic instrument, includes an ablation device. The ablation device includes an elongate member having first and second channels. First and second probes are disposed within the respective first and second channels. The first and second probes each define a central axis. The first and second probes each have substantially straight distal ends protruding from the distal ends of the respective first and second channels. The substantially straight distal ends define an outer surface. First and second electrodes are attached to a portion of the outer surface of the substantially straight distal ends of the respective first and second probes. The first and second electrodes are positioned in juxtaposed relationship with the central axis of the first and second probes. A distance between the first and second electrodes is adjustable by rotating at least one of the first and second probes about the respective central axis of the at least one of the first and second probes.
摘要翻译：诸如内窥镜或腹腔镜仪器的手术器械包括消融装置。消融装置包括具有第一和第二通道的细长构件。第一和第二探针设置在相应的第一和第二通道内。第一和第二探针均限定中心轴。第一和第二探头各自具有从相应的第一和第二通道的远端突出的基本上直的远端。基本上直的远端限定外表面。第一和第二电极附接到相应的第一和第二探针的基本上直的远端的外表面的一部分。第一和第二电极与第一和第二探针的中心轴线并置放置。第一和第二电极之间的距离可通过使第一和第二探针中的至少一个围绕第一和第二探针中的至少一个探针的相应中心轴旋转来调节。

7. 发明授权

US08160678B2 Methods and devices for repairing damaged or diseased tissue using a scanning beam assembly 有权
标题翻译：使用扫描光束组件修复受损或患病组织的方法和装置
公开(公告)号：US08160678B2
公开(公告)日：2012-04-17
申请号：US11764261
申请日：2007-06-18
申请人： Michael S. Cropper , Thomas W. Huitema , Michael P. Weir , Robert J. Dunki-Jacobs , Jere J. Brophy , Robert M. Trusty , Randal T. Byrum , David C. Youmans , Sean P. Conlon , Gary L. Long , Paul G. Ritchie , Jane A. Sheetz
发明人： Michael S. Cropper , Thomas W. Huitema , Michael P. Weir , Robert J. Dunki-Jacobs , Jere J. Brophy , Robert M. Trusty , Randal T. Byrum , David C. Youmans , Sean P. Conlon , Gary L. Long , Paul G. Ritchie , Jane A. Sheetz
IPC分类号： A61B5/05
CPC分类号： A61M25/1011 , A61B1/00082 , A61B1/00096 , A61B1/00101 , A61B1/00172 , A61B1/042 , A61B1/0623 , A61B1/07 , A61B5/0062 , A61B5/0084 , A61B17/22 , A61B18/24 , A61B90/361 , A61B2017/005 , A61B2017/22082 , A61B2017/22085 , A61B2017/22087 , A61B2018/2025 , A61B2018/20351 , A61M29/02 , A61N5/0601 , A61N5/062 , Y10S623/902
摘要： A method for repairing or modifying an area of a patient's anatomy that comprises directing at least a portion of a scanning beam assembly to an area of a patient's anatomy, applying a radiation-responsive agent to portion of the anatomy, and exposing the radiation-responsive agent to radiation directed onto the agent by the reflector to cause the agent to therapeutically interact with the site. The scanning beam assembly including a radiation source capable of emitting radiation, a reflector that receives the radiation from the radiation source to direct the radiation onto the anatomy, wherein the reflector oscillates in at least two directions to create a scan of the anatomy, a detector to detect radiation returned from the anatomy, and a controller to convert the detected radiation into a displayable anatomy image.
摘要翻译：一种用于修复或修改患者解剖结构的区域的方法，其包括将扫描束组件的至少一部分引导至患者解剖结构的区域，将辐射响应剂施加到解剖结构的一部分，以及暴露辐射响应试剂通过反射器引导到药剂上以使药剂与该部位进行治疗相互作用。扫描光束组件包括能够发射辐射的辐射源，接收来自辐射源的辐射以将辐射引导到解剖结构上的反射器，其中反射器在至少两个方向上振荡以产生解剖结构的扫描，检测器以检测从解剖结构返回的辐射，以及控制器，用于将检测到的辐射转换成可显示的解剖图像。

8. 发明申请

US20110190764A1 SURGICAL INSTRUMENT COMPRISING AN ELECTRODE 审中-公开
标题翻译：包含电极的手术仪器
公开(公告)号：US20110190764A1
公开(公告)日：2011-08-04
申请号：US12696598
申请日：2010-01-29
申请人： Gary L. Long , William D. Dannaher , Ragae M. Ghabrial
发明人： Gary L. Long , William D. Dannaher , Ragae M. Ghabrial
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/126 , A61B2018/1425 , A61B2018/1435
摘要： A surgical instrument configured to deliver electrical energy to the tissue of a patient, comprising a first electrode comprising a distal portion configured to contact the tissue and a second electrode comprising a distal portion configured to be inserted into the tissue, wherein the distal portion of the second electrode at least partially encompasses the distal portion of the first electrode.
摘要翻译：一种外科器械，被配置为将电能传递到患者的组织，所述外科器械包括第一电极，所述第一电极包括构造成接触所述组织的远侧部分和包括构造成插入所述组织的远侧部分的第二电极，其中，第二电极至少部分地包围第一电极的远端部分。

9. 发明申请

US20110152859A1 SURGICAL INSTRUMENT COMPRISING AN ELECTRODE 有权
标题翻译：包含电极的手术仪器
公开(公告)号：US20110152859A1
公开(公告)日：2011-06-23
申请号：US12641837
申请日：2009-12-18
申请人： Gary L. Long , David N. Plescia
发明人： Gary L. Long , David N. Plescia
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2017/00221 , A61B2018/00083 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2090/065 , A61N1/327
摘要： A surgical instrument can comprise a first electrode, a second electrode, and a retractable sheath. At least one of the electrodes can comprise an insulative jacket extending along the length thereof which can comprise a tissue stop for limiting the progression of the electrode into tissue. In various embodiments, a surgical instrument can comprise a first electrode, a second electrode, and a displaceable arc guard positioned between the electrodes. In certain embodiments, a surgical instrument can comprise an electrode including a flexible mesh configured to conform to the tissue against which it is positioned.
摘要翻译：手术器械可以包括第一电极，第二电极和可缩回护套。电极中的至少一个可以包括沿着其长度延伸的绝缘护套，其可以包括用于限制电极进入组织的进展的组织止动器。在各种实施例中，外科器械可以包括位于电极之间的第一电极，第二电极和可移位的电弧护罩。在某些实施例中，手术器械可以包括电极，其包括被配置为与其所定位的组织一致的柔性网状物。

10. 发明申请

US20100179530A1 ELECTRICAL ABLATION DEVICES 有权
标题翻译：电气设备
公开(公告)号：US20100179530A1
公开(公告)日：2010-07-15
申请号：US12352375
申请日：2009-01-12
申请人： Gary L. Long , Ragae M. Ghabrial , David N. Plescia , Omar J. Vakharia
发明人： Gary L. Long , Ragae M. Ghabrial , David N. Plescia , Omar J. Vakharia
IPC分类号： A61B18/18 , A61B18/14
CPC分类号： A61B18/1492 , A61B18/1206 , A61B18/1477 , A61B2018/00214 , A61B2018/00482 , A61B2018/00547 , A61B2018/00577 , A61B2018/00613 , A61B2018/00898 , A61B2018/124 , A61B2018/1425
摘要： An electrical ablation apparatus comprises first and second electrodes. Each electrode comprises a first end configured to couple an energy source and a second end configured to couple to a tissue treatment region. An energy source is coupled to the first and second electrodes. The energy source is configured to deliver a first series of electrical pulses sufficient to induce cell necrosis by irreversible electroporation and a second series of electrical pulses sufficient to induce cell necrosis by thermal heating, through at least one of the first and second electrodes. The first series of electrical pulses is characterized by a first amplitude, a first pulse length, and a first frequency. The second series of electrical pulses is characterized by a second amplitude, a second pulse length, and a second frequency.
摘要翻译：电切除装置包括第一和第二电极。每个电极包括构造成耦合能量源的第一端和被配置为耦合到组织治疗区域的第二端。能量源耦合到第一和第二电极。能量源被配置为递送足以通过不可逆电穿孔诱导细胞坏死的第一系列电脉冲和通过热加热通过第一和第二电极中的至少一个足以诱导细胞坏死的第二系列电脉冲。第一系列电脉冲的特征在于第一幅度，第一脉冲长度和第一频率。第二系列电脉冲的特征在于第二幅度，第二脉冲长度和第二频率。

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