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1. 发明授权

US08021363B2 Dual-bend sphinctertome 有权
标题翻译：双弯括约肌切开术
公开(公告)号：US08021363B2
公开(公告)日：2011-09-20
申请号：US11741198
申请日：2007-04-27
申请人： Omar J. Vakharia , Rudolph H. Nobis , Christopher Paul Swain , Charles Alexander Mosse , Keiichi Ikeda
发明人： Omar J. Vakharia , Rudolph H. Nobis , Christopher Paul Swain , Charles Alexander Mosse , Keiichi Ikeda
IPC分类号： A61B18/14 , A61B17/32
CPC分类号： A61B18/1492 , A61B17/320016 , A61B17/32056 , A61B2017/00278 , A61B2017/003 , A61B2018/1407 , A61B2018/144 , A61B2018/1467 , A61B2018/1475
摘要： Disclosed herein are devices and methods for forming multidirectional cuts in tissue. The tissue cutting devices disclosed herein generally include a flexible elongate member with at least first and second wires that are at least partially constrained within or along a portion of the member. A distal portion of the wires is anchored on or within a portion of the elongate member. When tension is applied to one of the wires, such as by an actuator at a proximal end of the device, the elongate member bows while an unconstrained portion of the wire becomes exposed relative to the adjacent portion of the elongate member, assuming a tissue-cutting configuration.
摘要翻译：本文公开了用于在组织中形成多向切割的装置和方法。本文公开的组织切割装置通常包括柔性细长构件，其具有至少部分地限制在构件的一部分内或沿构件的一部分的至少第一和第二导线。电线的远端部分锚定在细长构件的一部分上或内部。当例如通过设备近端的致动器将张力施加到一个电线上时，细长构件弯曲，同时线的非约束部分相对于细长构件的相邻部分露出，假设组织 - 切割配置。

2. 发明申请

US20070255299A1 Dual-Bend Sphinctertome 有权
标题翻译：双弯曲括约肌切开术
公开(公告)号：US20070255299A1
公开(公告)日：2007-11-01
申请号：US11741198
申请日：2007-04-27
申请人： Omar J. Vakharia , Rudolph H. Nobis , Christopher Paul Swain , Charles Alexander Mosse , Keiichi Ikeda
发明人： Omar J. Vakharia , Rudolph H. Nobis , Christopher Paul Swain , Charles Alexander Mosse , Keiichi Ikeda
IPC分类号： A61B17/32
CPC分类号： A61B18/1492 , A61B17/320016 , A61B17/32056 , A61B2017/00278 , A61B2017/003 , A61B2018/1407 , A61B2018/144 , A61B2018/1467 , A61B2018/1475
摘要： Disclosed herein are devices and methods for forming multidirectional cuts in tissue. The tissue cutting devices disclosed herein generally include a flexible elongate member with at least first and second wires that are at least partially constrained within or along a portion of the member. A distal portion of the wires is anchored on or within a portion of the elongate member. When tension is applied to one of the wires, such as by an actuator at a proximal end of the device, the elongate member bows while an unconstrained portion of the wire becomes exposed relative to the adjacent portion of the elongate member, assuming a tissue-cutting configuration.
摘要翻译：本文公开了用于在组织中形成多向切割的装置和方法。本文公开的组织切割装置通常包括柔性细长构件，其具有至少部分地限制在构件的一部分内或沿构件的一部分的至少第一和第二导线。电线的远端部分锚定在细长构件的一部分上或内部。当例如通过设备近端的致动器将张力施加到一个电线上时，细长构件弯曲，同时线的非约束部分相对于细长构件的相邻部分露出，假设组织 - 切割配置。

3. 发明授权

US07785348B2 Devices and methods of locking and cutting a suture in a medical procedure 有权
标题翻译：在医疗过程中锁定和切割缝线的装置和方法
公开(公告)号：US07785348B2
公开(公告)日：2010-08-31
申请号：US11127515
申请日：2005-05-12
申请人： Jesse J. Kuhns , Christopher Paul Swain , Charles Alexander Mosse , Omar J. Vakharia , Rudolph H. Nobis
发明人： Jesse J. Kuhns , Christopher Paul Swain , Charles Alexander Mosse , Omar J. Vakharia , Rudolph H. Nobis
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0487 , A61B17/06166 , A61B2017/0409 , A61B2017/0417 , A61B2017/0445 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052
摘要： Devices and methods are provided which may be used for suturing, including performing a totally transoral surgical procedure, such as a posterior gastropexy procedure. A suture lock and cut assembly is provided to lock and cut one or more sutures in one motion, which motion can be a non-curved, non rotational linear motion. The suture lock and cut assembly with one or more sutures threaded therethrough may be pushed through, for example, a patient's esophagus and into the stomach by the tip of an endoscope, or alternatively, sized to be fed through the working channel of the endoscope.
摘要翻译：提供了可以用于缝合的装置和方法，包括完成全面的手术操作，例如胃后路手术。提供缝合线锁和切割组件以在一个运动中锁定和切割一个或多个缝合线，该运动可以是非弯曲的非旋转线性运动。具有穿过其中的一个或多个缝合线的缝合线锁定和切割组件可以被推送通过例如患者的食道并且通过内窥镜的尖端被推入胃部，或者可选地尺寸设置成被馈送通过内窥镜的工作通道。

4. 发明授权

US08388653B2 T-type suture anchoring devices and methods of using same 有权
标题翻译： T型缝合线锚固装置及其使用方法
公开(公告)号：US08388653B2
公开(公告)日：2013-03-05
申请号：US11127513
申请日：2005-05-12
申请人： Rudolph H. Nobis , Frank Jankoski , Omar J. Vakharia , John A. Faux , Gregory J. Bakos , Duane A. Linenkugel , Christopher Paul Swain
发明人： Rudolph H. Nobis , Frank Jankoski , Omar J. Vakharia , John A. Faux , Gregory J. Bakos , Duane A. Linenkugel , Christopher Paul Swain
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0487 , A61B17/06166 , A61B2017/0409 , A61B2017/0417 , A61B2017/0445 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052
摘要： Suture anchoring devices are disclosed, including a T-tag anchoring device that is suitably small enough to fit into the hollow tip of a needle and, furthermore, provide protection to the suture against being cut or otherwise damaged by the sharp edge of the needle tip. One disclosed device includes a slot for providing a pivot point between the suture and the body when deployed, which can be employed to form a T-tag.
摘要翻译：公开了缝合线锚定装置，其包括T形锚定装置，其适当地足够小以适合于针的中空尖端，并且此外，为缝合线提供保护以免被针尖的尖锐边缘切割或以其它方式损伤。一个公开的装置包括用于在展开时在缝合线和主体之间提供枢轴点的槽，其可用于形成T形标签。

5. 发明申请

US20130085341A1 METHODS AND DEVICES FOR MANIPULATING TISSUE IN VIVO 审中-公开
标题翻译：用于在体液中操作组织的方法和装置
公开(公告)号：US20130085341A1
公开(公告)日：2013-04-04
申请号：US13249896
申请日：2011-09-30
申请人： Rudolph H. Nobis , Robert M. Trusty , James T. Spivey , Christopher J. Hess , Per O. Park , Omar J. Vakharia
发明人： Rudolph H. Nobis , Robert M. Trusty , James T. Spivey , Christopher J. Hess , Per O. Park , Omar J. Vakharia
IPC分类号： A61B1/32 , A61B17/34
CPC分类号： A61B17/29 , A61B17/07207 , A61B2017/00473 , A61B2017/00477
摘要： Methods and devices are provided for manipulating tissue in a body cavity, i.e., in vivo. In general, the methods and devices allow an end effector to engage tissue, be detached from a shaft used to control the end effector to engage the tissue, and then be moved to another location in the body cavity by a separate component, such as an external control unit. In some embodiments the end effector can include one or more deployable hooks that allow the end effector to remain at a surgical site independent of any shafts or external control units. Still further, in other embodiments the end effector can include a transverse bore to allow a second shaft to connect to the end effector to manipulate the tissue. Additional exemplary devices, kits, and methods related to manipulating tissue in vivo are also provided.
摘要翻译：提供了用于操作体腔中的组织，即体内的方法和装置。通常，方法和装置允许端部执行器接合组织，从用于控制末端执行器的轴分离以接合组织，然后通过单独的部件移动到体腔中的另一位置，例如外部控制单元。在一些实施例中，末端执行器可以包括一个或多个可展开的钩，其允许端部执行器独立于任何轴或外部控制单元而保持在手术位置。此外，在其他实施例中，端部执行器可以包括横向孔，以允许第二轴连接到末端执行器以操纵组织。还提供了与在体内操作组织相关的附加的示例性装置，试剂盒和方法。

6. 发明申请

US20100152539A1 POSITIONABLE IMAGING MEDICAL DEVICES 审中-公开
标题翻译：可定位成像医疗器械
公开(公告)号：US20100152539A1
公开(公告)日：2010-06-17
申请号：US12337340
申请日：2008-12-17
申请人： Ragae M. Ghabrial , Michael J. Stokes , Rudolph H. Nobis , Andrew M. Zwolinski , Michael P. Weir , David N. Plescia , Christle M. Cunningham , Omar J. Vakharia , William D. Fox , James T. Spivey
发明人： Ragae M. Ghabrial , Michael J. Stokes , Rudolph H. Nobis , Andrew M. Zwolinski , Michael P. Weir , David N. Plescia , Christle M. Cunningham , Omar J. Vakharia , William D. Fox , James T. Spivey
IPC分类号： A61B1/00
CPC分类号： A61B1/041 , A61B1/00029 , A61B1/00147 , A61B5/073 , A61B5/6882 , A61B34/73 , A61B2017/00283
摘要： A positionable imaging device includes a body defining a first end and a second end. The body is configured to be received within an internal body cavity. An imaging device is located at the first end of the body. A releasable fastener is coupled to the body to removably attach the imaging device to tissue within the internal body cavity. A release mechanism is coupled to the releasable fastener to detach the imaging device from the tissue.
摘要翻译：可定位成像装置包括限定第一端和第二端的主体。身体构造成被容纳在内部体腔内。成像装置位于身体的第一端。可拆卸紧固件联接到主体以将成像装置可移除地附接到内部体腔内的组织。释放机构联接到可释放紧固件以将成像装置与组织分离。

7. 发明授权

US07833223B2 Tri-bending sphinctertome 有权
标题翻译：三弯括约肌切开术
公开(公告)号：US07833223B2
公开(公告)日：2010-11-16
申请号：US11381006
申请日：2006-05-01
申请人： Omar Vakharia , Ifung Lu , Rudolph H. Nobis , Christopher Paul Swain
发明人： Omar Vakharia , Ifung Lu , Rudolph H. Nobis , Christopher Paul Swain
IPC分类号： A61B18/14 , A61B17/32
CPC分类号： A61B18/1492 , A61B17/320016 , A61B2017/003 , A61B2018/00553 , A61B2018/00601 , A61B2018/144 , A61B2018/1467
摘要： Disclosed herein are devices and methods for forming multidirectional cuts in tissue. The tissue cutting devices disclosed herein generally include a flexible elongate member with at least first, second, and third wires that are at least partially constrained within or along a portion of the member. A distal portion of the wires is anchored on or within a portion of the elongate member. When tension is applied to at least one of the wires, such as by an actuator at a proximal end of the device, the elongate member bows while an unconstrained portion of the wire becomes exposed relative to the adjacent portion of the elongate member, assuming a tissue-cutting configuration.
摘要翻译：本文公开了用于在组织中形成多向切割的装置和方法。本文公开的组织切割装置通常包括柔性细长构件，其具有至少部分地限制在构件的一部分内或沿着构件的一部分的至少第一，第二和第三导线。电线的远端部分锚定在细长构件的一部分上或内部。当张紧被施加到至少一根电线时，例如通过设备近端处的致动器，细长构件弯曲，同时线的非约束部分相对于细长构件的相邻部分露出，假定组织切割配置。

8. 发明申请

US20080188879A1 Tri-Bending Sphinctertome 有权
标题翻译：三弯矫形手术
公开(公告)号：US20080188879A1
公开(公告)日：2008-08-07
申请号：US11381006
申请日：2006-05-01
申请人： Omar Vakharia , Ifung Lu , Rudolph H. Nobis , Christopher Paul Swain
发明人： Omar Vakharia , Ifung Lu , Rudolph H. Nobis , Christopher Paul Swain
IPC分类号： A61B17/32
CPC分类号： A61B18/1492 , A61B17/320016 , A61B2017/003 , A61B2018/00553 , A61B2018/00601 , A61B2018/144 , A61B2018/1467
摘要： Disclosed herein are devices and methods for forming multidirectional cuts in tissue. The tissue cutting devices disclosed herein generally include a flexible elongate member with at least first, second, and third wires that are at least partially constrained within or along a portion of the member. A distal portion of the wires is anchored on or within a portion of the elongate member. When tension is applied to at least one of the wires, such as by an actuator at a proximal end of the device, the elongate member bows while an unconstrained portion of the wire becomes exposed relative to the adjacent portion of the elongate member, assuming a tissue-cutting configuration.
摘要翻译：本文公开了用于在组织中形成多向切割的装置和方法。本文公开的组织切割装置通常包括柔性细长构件，其具有至少部分地限制在构件的一部分内或沿着构件的一部分的至少第一，第二和第三导线。电线的远端部分锚定在细长构件的一部分上或内部。当张紧被施加到至少一根电线时，例如通过设备近端处的致动器，细长构件弯曲，同时线的非约束部分相对于细长构件的相邻部分露出，假定组织切割配置。

9. 发明授权

US07850686B2 Protective needle knife 有权
标题翻译：保护针刀
公开(公告)号：US07850686B2
公开(公告)日：2010-12-14
申请号：US11277998
申请日：2006-03-30
申请人： Rudolph H. Nobis , Kurt Bally , Christopher Paul Swain
发明人： Rudolph H. Nobis , Kurt Bally , Christopher Paul Swain
IPC分类号： A61B18/18
CPC分类号： A61B17/3415 , A61B17/3478 , A61B17/3494 , A61B17/3496 , A61B18/1477
摘要： Various methods and devices are provided for penetrating tissue. In one embodiment, a tissue-penetrating device is provided and includes a flexible elongate shaft and a flexible elongate wire extending through the elongate shaft and having a needle tip at a distal end thereof for penetrating tissue. The needle tip can be conductive and the elongate wire can be adapted to couple to an energy source for delivering energy to the needle tip to facilitate penetration of the needle tip through tissue. The device can also include a protective sheath disposed over at least a portion of the elongate shaft and movable relative to the elongate shaft between a distal position and a proximal position. The protective sheath is configured to either protect the needle tip or electrically isolate the needle tip after the needle tip is penetrated through tissue, thereby preventing unintentional penetration of adjacent tissue.
摘要翻译：提供用于穿透组织的各种方法和装置。在一个实施例中，提供组织穿透装置，并且包括柔性细长轴和延伸穿过细长轴并且在其远端处具有用于穿透组织的针尖的柔性细长线。针尖可以是导电的，并且细长线可以适于耦合到能量源，以将能量传递到针尖以促进针尖穿过组织。该装置还可以包括设置在细长轴的至少一部分上并且可在远侧位置和近端位置之间相对于细长轴移动的护套。保护套被构造成在针尖穿过组织之后保护针尖或电隔离针尖，从而防止相邻组织的无意穿透。

10. 发明授权

US08211114B2 Medical instrument having a medical snare 有权
标题翻译：具有医疗圈套的医疗器械
公开(公告)号：US08211114B2
公开(公告)日：2012-07-03
申请号：US11409732
申请日：2006-04-24
申请人： Rudolph H. Nobis , Ifung Lu
发明人： Rudolph H. Nobis , Ifung Lu
IPC分类号： A61B17/24 , A61B17/26
CPC分类号： A61B17/32056 , A61B2017/00867 , A61B2018/1407
摘要： A medical instrument including a resiliently flexible first elongate member and a resiliently flexible second elongate member. The first elongate member has a first proximal end portion and a first distal portion. The second elongate member has a second proximal end portion and a second distal portion, wherein the second distal portion is attached to the first distal portion, and wherein the attached first and second distal portions define a distal-loop medical snare which is insertable within a patient. In a first example, the first proximal end portion is lengthwise translatable with respect to the second proximal end portion to articulate the medical snare. In the same or a second example, the first proximal end portion is rotatable about its centerline to articulate the medical snare.
摘要翻译：一种医疗器械，包括弹性柔性的第一细长构件和弹性柔性的第二细长构件。第一细长构件具有第一近端部分和第一远端部分。所述第二细长构件具有第二近端部分和第二远端部分，其中所述第二远端部分附接到所述第一远端部分，并且其中所述附接的第一远端部分和所述第二远端部分限定远端环形医疗圈套，患者。在第一示例中，第一近端部分可相对于第二近端部分纵向平移，以便铰接医疗圈套。在相同或第二示例中，第一近端部分可围绕其中心线旋转以铰接医疗圈套。

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