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31. 发明授权

US08109984B2 Method and device for treatment of mitral insufficiency 有权
标题翻译：二尖瓣功能不全的治疗方法和装置
公开(公告)号：US08109984B2
公开(公告)日：2012-02-07
申请号：US11326546
申请日：2006-01-04
申请人： Jan Otto Solem , Per-Ola Kimblad , Randolf von Oepen , Bodo Quint , Gerd Seibold , Kenneth J. Michlitsch , Suk-Woo Ha , Karl-Ludwig Eckert , Ib Joergensen , Stevan Nielsen
发明人： Jan Otto Solem , Per-Ola Kimblad , Randolf von Oepen , Bodo Quint , Gerd Seibold , Kenneth J. Michlitsch , Suk-Woo Ha , Karl-Ludwig Eckert , Ib Joergensen , Stevan Nielsen
IPC分类号： A61F2/06
CPC分类号： A61F2/2451 , A61F2/07 , A61F2/88 , A61F2/90 , A61F2/91 , A61F2002/826 , A61F2002/828 , A61F2002/8483 , A61F2210/0004
摘要： A device for treatment of mitral annulus dilation is disclosed, wherein the device comprises two states. In a first of these states the device is insertable into the coronary sinus and has a shape of the coronary sinus. When positioned in the coronary sinus, the device is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.
摘要翻译：公开了一种用于治疗二尖瓣环扩张的装置，其中该装置包括两种状态。在这些状态中的第一个状态下，该装置可插入冠状窦并具有冠状窦的形状。当定位在冠状窦中时，假设曲率半径减小，装置可转移到第二状态，由此降低冠状窦的曲率半径和曲率半径以及二尖瓣环的圆周。

32. 发明申请

US20110015722A1 DEVICE AND METHOD FOR RESHAPING MITRAL VALVE ANNULUS 审中-公开
标题翻译：用于修复麻醉阀的装置和方法
公开(公告)号：US20110015722A1
公开(公告)日：2011-01-20
申请号：US12891522
申请日：2010-09-27
申请人： David L. Hauser , Donald E. Bobo, JR. , Jan Otto Solem
发明人： David L. Hauser , Donald E. Bobo, JR. , Jan Otto Solem
IPC分类号： A61F2/82 , A61F2/24
CPC分类号： A61F2/2454 , A61F2/2442 , A61F2/2445 , A61F2/246 , A61F2/2478 , A61F2/2487 , A61F2/82 , A61F2002/8483 , A61F2210/0004 , A61F2210/0014 , A61F2220/0016 , A61F2230/0004
摘要： Devices and methods for reshaping a mitral valve annulus are provided. One preferred device is configured for deployment in the right atrium and is shaped to apply a force along the atrial septum. The device causes the atrial septum to deform and push the anterior leaflet of the mitral valve in a posterior direction for reducing mitral valve regurgitation. Another preferred device is deployed in the left ventricular outflow tract at a location adjacent the aortic valve. The device is expandable for urging the anterior leaflet toward the posterior leaflet. Another preferred device comprises a tether configured to be attached to opposing regions of the mitral valve annulus.
摘要翻译：提供了用于重塑二尖瓣环的装置和方法。一个优选的装置被配置为在右心房中部署并且被成形为沿着房间隔施加力。该装置使得房间隔膜变形并沿着后方向推动二尖瓣的前叶，以减少二尖瓣反流。另一个优选的装置在邻近主动脉瓣的位置处部署在左心室流出道中。该装置是可扩张的，用于将前小叶推向后叶。另一个优选的装置包括构造成附接到二尖瓣环的相对区域的系绳。

33. 发明申请

US20100016877A1 Controllable Device, A Kit And A Method For Treatment Of Disorders In The Heart Rhythm Regulation System 审中-公开
标题翻译：可控装置，一套工具和一种治疗心律失常调节系统的方法
公开(公告)号：US20100016877A1
公开(公告)日：2010-01-21
申请号：US12298452
申请日：2006-05-17
申请人： Jan Otto Solem , Stevan Nielsen , Ib Joergensen , Gerd Seibold , Bodo Quint
发明人： Jan Otto Solem , Stevan Nielsen , Ib Joergensen , Gerd Seibold , Bodo Quint
IPC分类号： A61B17/32
CPC分类号： A61B17/320725 , A61B2017/00247 , A61B2017/00256 , A61B2017/2945 , A61B2017/32096 , A61B2018/00392 , A61B2090/037 , A61F2/2493 , A61F2/82
摘要： A tissue cutting device is disclosed, which is structured and arranged to be inserted through the vascular system into a body vessel adjacent to the heart and/or into the heart, and to be subsequently subjected to a change of shape in order to penetrate into the heart tissue. The device comprises at least one connection element that is arranged such that a connection formed from said connection element between a first and second part of said tissue cutting device is configured to break when said connection element is subjected to a specific external influence. The tissue cutting device may thus be used for controllably treating disorders to the heart rhythm regulation system. A kit of devices provides a plurality of devices for creating a lesion pattern for treating such disorders.
摘要翻译：公开了一种组织切割装置，其被构造和布置成通过血管系统插入邻近心脏和/或进入心脏的身体容器中，并且随后经受形状变化以便渗透到心脏组织该装置包括至少一个连接元件，其被布置成使得在所述组织切割装置的第一和第二部分之间从所述连接元件形成的连接被配置为当所述连接元件经受特定的外部影响时断开。因此，组织切割装置可用于可控地治疗心律调节系统的障碍。一套装置提供多个用于创建用于治疗这种疾病的损伤模式的装置。

34. 发明申请

US20090228100A1 Methods and Devices for Heart Valve Repair 审中-公开
标题翻译：心脏瓣膜修复的方法和设备
公开(公告)号：US20090228100A1
公开(公告)日：2009-09-10
申请号：US12471203
申请日：2009-05-22
申请人： Jan Otto Solem , Per Ola Kimblad , Stevan Nielsen , Ib Joergenson , Bodo Quint , Gerd Seibold , Randolf Von Oepen , Suk-Woo Ha , Karl-Ludwig Eckert , Stefan Schreck , Sepehr Fariabi , Tommy Conzelmann
发明人： Jan Otto Solem , Per Ola Kimblad , Stevan Nielsen , Ib Joergenson , Bodo Quint , Gerd Seibold , Randolf Von Oepen , Suk-Woo Ha , Karl-Ludwig Eckert , Stefan Schreck , Sepehr Fariabi , Tommy Conzelmann
IPC分类号： A61F2/24
CPC分类号： A61F2/2451
摘要： An elongate body including a proximal and distal anchor, and a bridge between the proximal and distal anchors. The bridge has an elongated state, having first axial length, and a shortened state, having a second axial length, wherein the second axial length is shorter than the first axial length. A resorbable thread may be woven into the bridge to hold the bridge in the elongated state and to delay the transfer of the bridge to the shortened state. In an additional embodiment, there may be one or more central anchors between the proximal and distal anchors with a bridge connecting adjacent anchors.
摘要翻译：包括近端和远端锚固件的细长主体以及近端和远端锚固件之间的桥梁。桥具有第一轴向长度的细长状态和具有第二轴向长度的缩短状态，其中第二轴向长度短于第一轴向长度。可再吸收的线可以编织到桥中以将桥梁保持在细长状态，并且将桥的传递延迟到缩短状态。在另外的实施例中，在近端和远端锚固件之间可以有一个或多个中心锚固件，其具有连接相邻锚固件的桥。

35. 发明授权

US06656213B2 Stent delivery system 有权
标题翻译：支架输送系统
公开(公告)号：US06656213B2
公开(公告)日：2003-12-02
申请号：US09884155
申请日：2001-06-20
申请人： Jan Otto Solem
发明人： Jan Otto Solem
IPC分类号： A61F206
CPC分类号： A61F2/95 , A61F2/958 , A61F2/97
摘要： A stent delivery system comprises a catheter having a distal end and a proximal end, and a self expanding stent device having a compressed state and an expanded state and being positioned along the catheter and close to the distal end thereof. The stent delivery system further comprises a capsule enclosing the self-expanding stent device in its compressed state along substantially the whole length thereof. The capsule has an open distal end and a proximal end fixed to the catheter. Further, the capsule has at least one perforation extending longitudinally of said capsule from the distal end substantially to the proximal end thereof. The stent delivery system also comprises a balloon positioned within the capsule so as to break the capsule along said at least one perforation when inflated, whereby the stent device may expand to its expanded state, Thereafter the catheter with the broken capsule may be withdrawn from a duct in which the catheter has been introduced to a desired position.
摘要翻译：支架输送系统包括具有远端和近端的导管，以及具有压缩状态和扩张状态的自扩张支架装置，并且沿着导管定位并且靠近其远端。支架输送系统还包括在其压缩状态下沿其大致整个长度包围自扩张支架装置的胶囊。胶囊具有敞开的远端和固定在导管上的近端。此外，胶囊具有至少一个从所述胶囊的远端延伸到大致至其近端的穿孔。支架输送系统还包括定位在胶囊内的气囊，以便当充气时沿着所述至少一个穿孔破裂胶囊，由此支架装置可以膨胀到其膨胀状态。此后，具有破裂的胶囊的导管可以从其中导管已经被引入到期望位置的导管。

36. 外观设计

USD438618S1 Graft connector 失效
标题翻译：移植连接器
公开(公告)号：USD438618S1
公开(公告)日：2001-03-06
申请号：US29119154
申请日：2000-02-25
申请人： Jan Otto Solem
设计人： Jan Otto Solem

37. 发明授权

US08764814B2 Tissue penetration device and method 有权
标题翻译：组织穿刺装置及方法
公开(公告)号：US08764814B2
公开(公告)日：2014-07-01
申请号：US13535131
申请日：2012-06-27
申请人： Jan Otto Solem
发明人： Jan Otto Solem
IPC分类号： A61F2/06 , A61F2/82
CPC分类号： A61F2/915 , A61F2/848 , A61F2/91 , A61F2002/075 , A61F2002/8483 , A61M25/0084
摘要： A medical device for canalization of a tissue comprises a radially expandable and crimpable or collapsible substantially tubular member that has a rear end, a front end, and a pattern of struts or a mesh of wires arranged in-between the rear end and the front end, arranged around an interior of the device. The tubular member has extensions, which are arranged towards the interior of the device in a first state of the device, and towards an exterior of the medical device in a second state of the device, wherein the second state of the medical device is the tubular member turned inside out. During storage, the device is restrained in a delivery catheter in the second state. During delivery the device turns outside in and digs into the tissue to create a channel therein, thus preventing or fixating debris or other matter to spread from the channel.
摘要翻译：用于导管组织的医疗装置包括径向可膨胀和可压缩或可收缩的基本上管状的构件，其具有后端，前端和支柱图案或布置在后端和前端之间的电线网，围绕设备的内部布置。管状构件具有延伸部，其在装置的第一状态下朝向装置的内部布置，并且在装置的第二状态下朝向医疗装置的外部布置，其中医疗装置的第二状态是管状会员转过身在储存期间，该装置被限制在处于第二状态的输送导管中。在输送期间，装置外部进入组织内并在组织中产生通道，从而防止或固定碎屑或其它物质从通道扩散。

38. 发明授权

US08709074B2 Method and device for treatment of mitral insufficiency 有权
标题翻译：二尖瓣功能不全的治疗方法和装置
公开(公告)号：US08709074B2
公开(公告)日：2014-04-29
申请号：US13366540
申请日：2012-02-06
申请人： Jan Otto Solem , Per-Ola Kimblad , Randolf von Oepen , Bodo Quint , Gerd Seibold , Kenneth J. Michlitsch , Suk-Woo Ha , Karl-Ludwig Eckert , Ib Joergensen , Stevan Nielsen
发明人： Jan Otto Solem , Per-Ola Kimblad , Randolf von Oepen , Bodo Quint , Gerd Seibold , Kenneth J. Michlitsch , Suk-Woo Ha , Karl-Ludwig Eckert , Ib Joergensen , Stevan Nielsen
IPC分类号： A61F2/06
CPC分类号： A61F2/2451 , A61F2/07 , A61F2/88 , A61F2/90 , A61F2/91 , A61F2002/826 , A61F2002/828 , A61F2002/8483 , A61F2210/0004
摘要： A device for treatment of mitral annulus dilation is disclosed, wherein the device comprises two states. In a first of these states the device is insertable into the coronary sinus and has a shape of the coronary sinus. When positioned in the coronary sinus, the device is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.
摘要翻译：公开了一种用于治疗二尖瓣环扩张的装置，其中该装置包括两种状态。在这些状态中的第一个状态下，该装置可插入冠状窦并具有冠状窦的形状。当定位在冠状窦中时，假设曲率半径减小，装置可转移到第二状态，由此降低冠状窦的曲率半径和曲率半径以及二尖瓣环的圆周。

39. 发明授权

US08216261B2 Tissue penetration device and method 有权
标题翻译：组织穿刺装置及方法
公开(公告)号：US08216261B2
公开(公告)日：2012-07-10
申请号：US12595568
申请日：2008-04-14
申请人： Jan Otto Solem
发明人： Jan Otto Solem
IPC分类号： A61B17/22 , A61B17/32 , A61F2/06
CPC分类号： A61F2/915 , A61F2/848 , A61F2/91 , A61F2002/075 , A61F2002/8483 , A61M25/0084
摘要： A medical device for canalization of a tissue of a body portion by penetration thereof, a kit, a manufacturing method and a method of canalization are disclosed. The device is adapted for trans-catheter delivery to the body portion, and comprises a radially expandable and crimpable or collapsible substantially tubular member that has a rear end, a front end, and a pattern of struts or a mesh of wires arranged in-between the rear end and the front end, arranged around an interior of the device. The tubular member has extensions, which are arranged towards the interior of the device in a first state of the device, and towards an exterior of the medical device in a second state of the device, wherein the second state of the medical device is the tubular member turned inside out. During storage, the device is restrained in a delivery catheter in the second state. During delivery the device turns outside in and digs into the tissue to create a channel therein, thus preventing or fixating debris or other matter to spread from the channel.
摘要翻译：公开了一种用于通过穿透身体部分的组织导尿的医疗装置，套件，制造方法和管道的方法。该装置适于将导管传送到主体部分，并且包括径向可膨胀和可压缩或可收缩的基本上管状的构件，其具有后端，前端和支撑图案或布置在其间的线网后端和前端，围绕装置的内部布置。管状构件具有延伸部，其在装置的第一状态下朝向装置的内部布置，并且在装置的第二状态下朝向医疗装置的外部布置，其中医疗装置的第二状态是管状会员转过身在储存期间，该装置被限制在处于第二状态的输送导管中。在输送期间，装置外部进入组织内并在组织中产生通道，从而防止或固定碎屑或其它物质从通道扩散。

40. 发明申请

US20120123522A1 METHOD OF TREATING A DILATED VENTRICLE 有权
标题翻译：处理稀释气道的方法
公开(公告)号：US20120123522A1
公开(公告)日：2012-05-17
申请号：US13357446
申请日：2012-01-24
申请人： David L. Hauser , Jan Otto Solem
发明人： David L. Hauser , Jan Otto Solem
IPC分类号： A61F2/82
CPC分类号： A61F2/2451 , A61F2/2481 , A61F2250/0007 , A61F2250/0031
摘要： A method of reducing ventricular dilation comprises placing one or more cardiac bridges into vessels extending along a length of the ventricle. Each cardiac bridge preferably includes a pair of anchors and a bridge member secured therebetween. The tension in the bridge member compresses the ventricle and thereby reduces the dilation along the ventricle wall. In another embodiment, the bridge member is tensioned to reshape the left ventricle for reducing tension on the chordae tendinae in the heart for improving valve function.
摘要翻译：减少心室扩张的方法包括将一个或多个心脏桥放置在沿着心室长度延伸的血管中。每个心桥优选地包括一对固定器和固定在它们之间的桥构件。桥梁构件中的张力压缩心室，从而减小沿心室壁的扩张。在另一个实施例中，桥接构件被张紧以重塑左心室，以减小心脏中腱索的张力，以改善瓣膜功能。

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