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31. 发明申请

US20120059381A1 BONE TREATMENT SYSTEMS AND METHODS 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20120059381A1
公开(公告)日：2012-03-08
申请号：US13282653
申请日：2011-10-27
申请人： John H. Shadduck , Csaba Truckai
发明人： John H. Shadduck , Csaba Truckai
IPC分类号： A61B17/58
CPC分类号： A61B17/7098
摘要： Methods and instruments for treating an osteoporotic vertebral body or for treating a vertebral compression fracture. An exemplary method includes introducing an open knit structure together with a bone cement into a bone wherein the knit structure extends substantially throughout the interior of the cement volume. In one aspect of the invention, the bone cement volumes cures with the filament structure reinforcing the cement. In another aspect of the invention, the open knit structure is configured to direct flows of bone cement to apply forces for reducing a vertebral compression fracture. In another aspect of the invention, the system provides bone cement flows that extend through the knit structure thus allowing the cement to fully interdigitate with the cancellous bone.
摘要翻译：用于治疗骨质疏松性椎体或用于治疗椎体压缩性骨折的方法和手段。一种示例性的方法包括将开放的针织结构与骨水泥一起引入到骨中，其中针织结构基本上在水泥体积的整个内部延伸。在本发明的一个方面，骨水泥体积固化，细丝结构增强了水泥。在本发明的另一方面，开放针织结构被配置为引导骨粘固剂的流动以施加用于减少椎骨压缩性骨折的力。在本发明的另一方面，该系统提供延伸穿过针织结构的骨水泥流，从而允许水泥与松质骨完全交叉指向。

32. 发明授权

US08070753B2 Bone treatment systems and methods 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US08070753B2
公开(公告)日：2011-12-06
申请号：US11196045
申请日：2005-08-02
申请人： Csaba Truckai , John H. Shadduck
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B17/58
CPC分类号： A61B17/7095 , A61B17/7098 , A61B17/864 , A61B17/8811 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61F2/44
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. An exemplary system utilizes Rf energy in combination a conductive bone fill material for polymerizing the surface of the inflow plume to control the geometry of the fill material and the application of force caused by inflows of fill material. In another embodiment, method of treating bone includes injecting a volume of fill material into a bone and selectively modifying a viscosity of a selected portion of the bone filler to control the direction of flow of the fill material within the bone. A system for treating bone using this method includes an introducer for delivering fill material into the bone and an energy source selectively coupleable to the fill material to alter the viscosity of the fill material as it flows out of the introducer.
摘要翻译：本发明在某些实施例中涉及用于治疗诸如椎体压缩性骨折的骨整形术程序的医疗装置。更具体地，本发明的实施例涉及通过控制引入松质骨的填充材料的几何形状来可控地恢复椎体高度的仪器和方法。示例性系统利用Rf能量组合导电骨填充材料，用于聚合流入羽流的表面以控制填充材料的几何形状以及由填充材料的流入引起的力的施加。在另一个实施方案中，治疗骨的方法包括将一定体积的填充材料注入骨中，并选择性地改变骨填充物的选定部分的粘度以控制填充材料在骨内的流动方向。使用这种方法治疗骨骼的系统包括用于将填充材料输送到骨骼中的导引器，以及选择性地与填充材料耦合的能量源，以改变填充材料流出导引器时的粘度。

33. 发明申请

US20110276045A1 ELECTROSURGICAL INSTRUMENT AND METHOD OF USE 审中-公开
标题翻译：静电仪器及其使用方法
公开(公告)号：US20110276045A1
公开(公告)日：2011-11-10
申请号：US13101182
申请日：2011-05-05
申请人： Csaba Truckai , John H. Shadduck
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B18/08 , A61B17/28 , A61B18/18
CPC分类号： A61B18/1442
摘要： A particular embodiment of the invention provides an electrosurgical working end for performing high strength welding of tissue comprising a body having a tissue contacting energy delivery surface. The body includes pixel portions and non-pixel portions distributed within the tissue contacting surface. The pixel portions comprise a positive temperature coefficient of resistance (PTCR) material with at least one pixel portion configured to switch Rf current on and off in the at least one pixel portion responsive to tissue temperature adjacent the at least one pixel portion. The pixel portions can be configured to be coupled to an Rf current source such as an Rf generator. The pixelated energy delivery surfaces are capable of highly localized modulation of Rf energy application to the engaged tissue to create high strength tissue welds.
摘要翻译：本发明的一个具体实施方案提供了一种电外科工作端，用于对组织进行高强度焊接，包括具有组织接触能量输送表面的主体。主体包括分布在组织接触表面内的像素部分和非像素部分。像素部分包括正温度系数电阻（PTCR）材料，其中至少一个像素部分被配置成响应于与至少一个像素部分相邻的组织温度在至少一个像素部分中开启和关闭Rf电流。像素部分可以被配置为耦合到诸如Rf发生器的Rf电流源。像素化的能量传递表面能够对接合的组织进行Rf能量的高度局部调节，以产生高强度组织焊接。

34. 发明申请

US20100174286A1 BONE TREATMENT SYSTEMS AND METHODS FOR INTRODUCING AN ABRADING STRUCTURE TO ABRADE BONE 有权
标题翻译：用于引导骨质疏松结构的骨治疗系统和方法
公开(公告)号：US20100174286A1
公开(公告)日：2010-07-08
申请号：US12729004
申请日：2010-03-22
申请人： Csaba Truckai , John H. Shadduck
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B17/00
CPC分类号： A61B17/32002 , A61B17/1615 , A61B17/1617 , A61B17/1631 , A61B17/1642 , A61B17/1668 , A61B17/1671 , A61B17/320725 , A61B2017/00261 , A61B2017/00557 , A61B2017/320004 , A61B2217/005 , A61B2217/007 , A61M1/0082
摘要： The invention provides instruments and methods for prophylactic treatment of an osteoporotic vertebral body or for treating a vertebral compression fracture (VCF). In one exemplary method, a probe system uses a high speed rotational elastomeric cutter having an optional expandable abrasive surface for abrading or cutting at least one path or region within vertebral cancellous bone. Irrigation and aspiration sources are included in the probe system for removing abraded bone debris. In one embodiment, the high speed rotational abrader uses a tissue-selective abrading surface that abrades or cuts bone but does not cut soft tissue. In another embodiment, an expandable abrading surface allows the treatment of bone with low pressures to create paths or spaces without explosive expansion forces known in prior art balloon procedures that are designed to crush and compact cancellous bone in a vertebra. After the creation of a path or space, an in-situ hardenable bone cement volume is introduced into each path or space to support the vertebra.
摘要翻译：本发明提供了用于预防性治疗骨质疏松性椎体或用于治疗椎体压缩性骨折（VCF）的仪器和方法。在一个示例性方法中，探针系统使用具有可选的可扩展研磨表面的高速旋转弹性体切割器，用于研磨或切割椎骨松质骨内的至少一个路径或区域。用于清除磨损的骨碎片的探针系统中包含灌溉和吸入源。在一个实施例中，高速旋转磨擦机使用磨损或切割骨骼而不切割软组织的组织选择性研磨表面。在另一个实施方案中，可膨胀研磨表面允许用低压处理骨骼以产生路径或空间，而不会在现有技术的球囊过程中已知的爆炸膨胀力被设计成压缩和压紧椎骨中的松质骨。在创建路径或空间之后，将原位可硬化的骨水泥体积引入到每个路径或空间中以支撑椎骨。

35. 发明申请

US20100030220A1 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：US20100030220A1
公开(公告)日：2010-02-04
申请号：US12512505
申请日：2009-07-30
申请人： Csaba Truckai , John H. Shadduck
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B17/58 , A61N1/39
CPC分类号： A61B17/8816 , A61B17/8822 , A61B17/8836
摘要： Systems and methods for treating vertebral compression fractures are provided. In one embodiment, a bone cement injector system can include a first handle component that is detachably coupled to a second sleeve component having a distal end configured for positioning in bone, and a flow channel extending through the first and second components. The system can include a thermal energy emitter. The flow channel can have a flow channel surface with a material that that limits cement flow turbulence. At least a portion of the flow channel can have a non-round cross section.
摘要翻译：提供了治疗椎体压缩性骨折的系统和方法。在一个实施例中，骨粘固剂注射器系统可以包括第一手柄部件，其可拆卸地联接到具有被配置为定位在骨头中的远端的第二套筒部件和延伸穿过第一和第二部件的流动通道。该系统可以包括热能发射器。流动通道可以具有流动通道表面，其具有限制水泥流动湍流的材料。流动通道的至少一部分可以具有非圆形横截面。

36. 发明授权

US07517349B2 Electrosurgical instrument and method 有权
标题翻译：电外科仪器和方法
公开(公告)号：US07517349B2
公开(公告)日：2009-04-14
申请号：US11199555
申请日：2005-08-08
申请人： Csaba Truckai , John H. Shadduck
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B18/14 , A61B18/12
CPC分类号： A61B18/1492 , A61B18/1442 , A61B2018/00077 , A61B2018/00083 , A61B2018/00148 , A61B2018/00404 , A61B2018/0063 , A61B2018/00702 , A61B2018/00809 , A61B2090/064
摘要： An electrosurgical instrument and method for treating varicose veins. In one embodiment, an elongate catheter has a distal working end that carries an electrosurgical energy delivery surface comprising at least one electrode with a positive temperature coefficient of resistance (PTCR) surface and/or an electrode with a pressure sensitive variable resistance to provide a smart surface for controlling Rf current flow at the interface of electrosurgical surface and the tissue. The electrode surface then can limit or modulate Rf energy delivery through the surface in response to the temperature of the surface or the engagement pressure of the surface against the engaged tissue. In operation, the smart electrosurgical surface prevents arcing at the electrode-tissue interface, and thus controls ohmic heating to prevent tissue desiccation, charring and emboli formation.
摘要翻译：一种用于治疗静脉曲张的电外科器械和方法。在一个实施例中，细长导管具有远端工作端，其承载电外科能量输送表面，其包括具有正温度系数电阻（PTCR）表面的至少一个电极和/或具有压敏可变电阻的电极，以提供智能用于控制电外科表面和组织界面处的Rf电流的表面。电极表面然后可以响应于表面的温度或表面对接合的组织的接合压力而限制或调节通过表面的Rf能量传递。在操作中，智能电外科表面防止电极 - 组织界面处的电弧，从而控制欧姆加热以防止组织干燥，炭化和栓塞形成。

37. 发明申请

US20080269761A1 BONE TREATMENT SYSTEMS AND METHODS 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20080269761A1
公开(公告)日：2008-10-30
申请号：US12112477
申请日：2008-04-30
申请人： Csaba Truckai , John H. Shadduck , Robert Luzzi
发明人： Csaba Truckai , John H. Shadduck , Robert Luzzi
IPC分类号： A61B17/58 , A61N1/00 , A61B19/00
CPC分类号： A61B17/8822 , A61B17/88 , A61B17/8805 , A61B17/8811 , A61B17/8816 , A61B17/8836
摘要： The present invention relates in certain embodiments to systems and methods for treating bone, such as vertebral compression fractures. In one embodiment, a method includes controllably applying energy from an energy source to a bone cement volume outside of a patient's body to selectively accelerate the polymerization rate of the bone fill material volume prior to introduction of the bone fill material into a bone. The method further includes sequentially introducing a plurality of cement carrying structures with said accelerated polymerization rate bone cement volume into the bone. A system for use in said method includes at least one elongated cement-carrying structure sized to carry a bone cement volume therein and an energy source operatively coupleable to the cement-carrying structure. The energy source applies energy to the bone cement volume to selectively accelerate a polymerization rate thereof. An elongated injector is insertable into the bone and has a passageway that removably receives the elongated cement-carrying structure to allow delivery of the accelerated polymerization rate bone cement into the bone.
摘要翻译：本发明在某些实施方案中涉及用于治疗骨骼的系统和方法，例如椎体压缩性骨折。在一个实施例中，一种方法包括将能量源可控地施加到患者身体外部的骨水泥体积，以在将骨填充材料引入骨骼之前选择性地加速骨填充材料体积的聚合速率。该方法还包括将具有所述加速聚合速率骨水泥体积的多个水泥承载结构顺序地引入骨中。用于所述方法的系统包括尺寸适于承载骨水泥体积的至少一个细长的水泥承载结构，以及可操作地连接到承载结构的能量源。能量源将能量施加到骨水泥体积以选择性地加速其聚合速率。细长的注射器可插入到骨中并且具有可移除地容纳细长的水泥承载结构以允许将加速的聚合速率骨水泥递送到骨中的通道。

38. 发明授权

US07311709B2 Electrosurgical instrument and method of use 有权
标题翻译：电外科仪器及使用方法
公开(公告)号：US07311709B2
公开(公告)日：2007-12-25
申请号：US10448478
申请日：2003-05-30
申请人： Csaba Truckai , James A. Baker , John H. Shadduck
发明人： Csaba Truckai , James A. Baker , John H. Shadduck
IPC分类号： A61B18/12
CPC分类号： A61B18/1442 , A61B2018/00077 , A61B2018/00083 , A61B2018/00148 , A61B2018/0063 , A61B2018/00654 , A61B2018/00791 , A61B2018/00797 , A61B2018/00809 , A61B2018/1467
摘要： An electrosurgical medical device and method for creating thermal welds in engaged tissue. In one embodiment, at least one jaw of the instrument defines a tissue engagement plane carrying a variable resistive body of a positive temperature coefficient material that has a selected decreased electrical conductance at each selected increased temperature thereof over a targeted treatment range. The variable resistive body can be engineered to bracket a targeted thermal treatment range, for example about 60° C. to 80° C., at which tissue welding can be accomplished. In one mode of operation, the engagement plane will automatically modulate and spatially localize ohmic heating within the engaged tissue from Rf energy application across micron-scale portions of the engagement surface. In another mode of operation, a variable resistive body will focus conductive heating in a selected portion of the engagement surface.
摘要翻译：一种用于在接合组织中产生热焊缝的电外科医疗装置和方法。在一个实施例中，仪器的至少一个钳口限定了携带正温度系数材料的可变电阻体的组织接合平面，其在目标治疗范围内的每个选定的升高温度下具有选定的降低的电导率。可变电阻体可以被设计成支撑目标热处理范围，例如约60℃至80℃，在该热处理范围内可以实现组织焊接。在一种操作模式中，接合平面将自动地调节并且在接合表面的微米级部分的Rf能量施加之间空间地定位所接合组织内的欧姆加热。在另一种操作模式中，可变电阻体将导电加热聚焦在接合表面的选定部分中。

39. 发明授权

US07306598B2 Polymer matrix devices for treatment of vascular malformations 有权
标题翻译：用于治疗血管畸形的聚合物基质装置
公开(公告)号：US07306598B2
公开(公告)日：2007-12-11
申请号：US10456113
申请日：2003-06-05
申请人： Csaba Truckai , John H. Shadduck
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B18/18 , A61B5/04
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12118 , A61B17/12145 , A61B17/12168 , A61B17/12172 , A61B17/12181 , A61B2017/12068 , A61F2/07 , A61F2/848 , A61F2/90 , A61F2220/0016
摘要： A system for treating a wide-neck aneurysm comprising a mesh-like sleeve fabricated from a class of polymer filaments that carry conductive particles therein to provide the filaments with a specified resistivity. The releasable mesh-like sleeve is introduced to the site of a targeted vascular malformation by the working end of a catheter that carries an electrode arrangement at its distal terminus. The system further provides an electrical source and controller (i) that modulates power delivery to the polymer matrix which can then fuse the sleeve to the wall of a blood vessel to span across the vascular malformation.
摘要翻译：一种用于治疗宽颈动脉瘤的系统，包括由一类聚合物长丝制成的网状套筒，所述聚合物细丝在其中携带导电颗粒以提供具有指定电阻率的细丝。可释放的网状套筒通过导管的工作端引导到目标血管畸形部位，该导管在其远端具有电极装置。该系统还提供一种电源和控制器（i），其调节向聚合物基质的功率传递，然后可将该套管熔合到血管的壁以横跨血管畸形。

40. 发明授权

US07186253B2 Electrosurgical jaw structure for controlled energy delivery 有权
标题翻译：用于受控能量输送的电外科钳口结构
公开(公告)号：US07186253B2
公开(公告)日：2007-03-06
申请号：US11118881
申请日：2005-04-29
申请人： Csaba Truckai , James Baker , Bruno Strul , John H. Shadduck
发明人： Csaba Truckai , James Baker , Bruno Strul , John H. Shadduck
IPC分类号： A61B18/14 , A61B18/12
CPC分类号： A61B18/1442 , A61B2018/00077 , A61B2018/00083 , A61B2018/00148 , A61B2018/0063 , A61B2018/00809
摘要： A working end of a surgical instrument that carries first and second jaws for delivering energy to tissue. In a preferred embodiment, at least one jaw of the working end defines a tissue-engagement plane that contacts the targeted tissue. The cross-section of the engagement plane reveals that it defines a surface conductive portion that overlies a variably resistive matrix of a temperature-sensitive resistive material or a pressure-sensitive resistive material. An interior of the jaw carries a conductive material or electrode that is coupled to an Rf source and controller. In an exemplary embodiment, the variably resistive matrix can comprise a positive temperature coefficient (PTC) material, such as a ceramic, that is engineered to exhibit a dramatically increasing resistance (i.e., several orders of magnitude) above a specific temperature of the material.
摘要翻译：手术器械的工作端，其携带用于将能量递送至组织的第一和第二钳口。在优选实施例中，工作端的至少一个钳口限定了接触目标组织的组织接合平面。接合平面的横截面显示它限定了覆盖在温度敏感电阻材料或压敏电阻材料的可变电阻矩阵上的表面导电部分。钳口的内部承载耦合到Rf源和控制器的导电材料或电极。在示例性实施例中，可变电阻矩阵可以包括正温度系数（PTC）材料，例如陶瓷，其被工程化以显示高于材料的特定温度的显着增加的电阻（即几个数量级）。

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