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21. 发明申请

US20130324984A1 DEVICE AND PROCESS FOR MACHINING THE CORNEA OF A HUMAN EYE WITH FOCUSED PULSED LASER RADIATION 有权
标题翻译：用聚焦脉冲激光辐射加工人眼的脊椎的装置和方法
公开(公告)号：US20130324984A1
公开(公告)日：2013-12-05
申请号：US13984392
申请日：2011-02-15
申请人： Theo Seiler , Mathias Woelfel , Christof Donitzky
发明人： Theo Seiler , Mathias Woelfel , Christof Donitzky
IPC分类号： A61F9/008
CPC分类号： A61F9/00836 , A61F2/147 , A61F9/00831 , A61F2009/00872
摘要： A device for machining the cornea of a human eye with focused pulsed laser radiation includes controllable components, a control computer for controlling these components and a control program for the control computer. The control program contains instructions that are designed to generate an incision figure in the cornea permitting the insertion of an intrastromal corneal ring implant. The incision figure includes a ring incision situated totally deep within the corneal tissue and an opening incision extending at right angles to the ring plane of the ring incision from the anterior surface of the cornea or from the posterior surface of the cornea as far as at least the ring incision. The ring incision exhibits, assigned to the opening incision (44), a radial—relative to the ring axis—widening zone in which the opening incision impinges on the ring incision.
摘要翻译：用聚焦脉冲激光辐射加工人眼角膜的装置包括可控组件，用于控制这些组件的控制计算机和用于控制计算机的控制程序。控制程序包含设计用于在角膜中产生切口图的指令，允许插入椎间孔内角膜环植入物。切口图包括位于角膜组织内完全深的环形切口和从角膜前表面或角膜后表面直角延伸到环形切口的环形平面的开口切口，至少至少环切口。所述环形切口在所述开口切口（44）中表现出相对于所述开口切口撞击所述环切口的所述环形轴线加宽区域的径向。

22. 发明申请

US20130197634A1 APPARATUS FOR PATTERNED PLASMA-MEDIATED LASER TREPHINATION OF THE LENS CAPSULE AND THREE DIMENSIONAL PHACO-SEGMENTATION 有权
标题翻译：用于图案等离子体介质激光照射镜片胶囊和三维PHACO分段的装置
公开(公告)号：US20130197634A1
公开(公告)日：2013-08-01
申请号：US13801482
申请日：2013-03-13
申请人： OPTIMEDICA CORPORATION
发明人： Daniel V. Palanker , Mark S. Blumenkranz , Dan E. Andersen , David H. Mordaunt
IPC分类号： A61B18/20 , A61F2/16
CPC分类号： A61F9/008 , A61B18/20 , A61B90/361 , A61B2018/00577 , A61F2/1602 , A61F9/00736 , A61F9/00754 , A61F9/00812 , A61F9/00814 , A61F9/00825 , A61F9/00831 , A61F9/00834 , A61F9/00836 , A61F9/00838 , A61F9/0084 , A61F9/009 , A61F2009/00844 , A61F2009/00851 , A61F2009/00865 , A61F2009/0087 , A61F2009/00878 , A61F2009/00882 , A61F2009/00887 , A61F2009/00889 , A61F2009/00895 , A61F2009/00897
摘要： System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.
摘要翻译：用于在不同深度进行眼组织切口的系统和方法。该系统和方法聚焦在眼睛组织内各种深度的各种焦点上，可能是模式。分段镜头可用于同时创建多个焦点。可以通过顺序或同时聚焦不同深度的光来实现最佳切口，产生扩张的等离子体柱，并且产生具有细长腰部的光束。

23. 发明申请

US20120150161A1 SYSTEM AND METHOD FOR INCISING MATERIAL 有权
标题翻译：用于材料的系统和方法
公开(公告)号：US20120150161A1
公开(公告)日：2012-06-14
申请号：US13400345
申请日：2012-02-20
申请人： Ferenc Raksi , Michael Brownell
发明人： Ferenc Raksi , Michael Brownell
IPC分类号： A61F9/01
CPC分类号： A61F9/008 , A61F9/00829 , A61F9/00831 , A61F9/00836 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882 , A61F2009/00897
摘要： Systems and methods of incising a portion of a material include creating a sub-surface separation in a region of the material, and incising a periphery of the region with a pulsed laser beam to produce an edge of the portion. The edge includes a periodically varying shape to secure the portion to the material when the portion is reintegrated. The system includes a laser producing the pulsed laser beam, a scanner operable in response to a control signal, and a controller coupled to the scanner. The controller produces the control signal. In response to the control signal, the scanner creates a sub-surface separation in the region with the pulsed laser beam and incises the periphery of the region with the pulsed laser beam to produce the edge with the periodically varying shape.
摘要翻译：切割材料的一部分的系统和方法包括在材料的区域中产生亚表面分离，以及用脉冲激光束切割该区域的周边以产生该部分的边缘。该边缘包括周期性变化的形状，以便当该部分重新整合时将该部分固定到该材料上。该系统包括产生脉冲激光束的激光器，可响应于控制信号操作的扫描器和耦合到扫描器的控制器。控制器产生控制信号。响应于控制信号，扫描器利用脉冲激光束在该区域中产生子表面间隔，并用脉冲激光束切割该区域的周边以产生具有周期性变化形状的边缘。

24. 发明申请

US20120150160A1 Apparatus for laser surgical ophthalmology 审中-公开
标题翻译：激光手术眼科仪器
公开(公告)号：US20120150160A1
公开(公告)日：2012-06-14
申请号：US13365449
申请日：2012-02-03
申请人： Klaus Vogler , Christof Donitzky
发明人： Klaus Vogler , Christof Donitzky
IPC分类号： A61F9/011 , A61F9/01
CPC分类号： A61F9/008 , A61B2017/00508 , A61B2017/00517 , A61F9/0081 , A61F9/00831 , A61F9/00836 , A61F2009/00872 , A61F2009/00897
摘要： The invention relates to an apparatus for laser surgical ophthalmology, comprising a source of pulsed femtosecond laser radiation, components for guiding and focusing the laser radiation onto or into a tissue of an eye to be treated, a control unit controlling the source, which has been set up to switch the source between at least two operating modes with respectively differing radiation properties of the laser radiation, wherein in a first operating mode the radiation properties of the laser radiation are matched to the placement of an incision in the tissue, and in a second operating mode the radiation properties of the laser radiation are matched to a welding or cross-linking of the tissue.
摘要翻译：本发明涉及一种用于激光手术眼科的装置，包括脉冲飞秒激光辐射源，用于将激光辐射引导和聚焦到待治疗的眼睛的组织上或组合的组件，控制源的控制单元设置为在至少两个操作模式之间切换源，分别具有不同的激光辐射的辐射特性，其中在第一操作模式中，激光辐射的辐射特性与切片在组织中的放置相匹配，并且在第二操作模式，激光辐射的辐射特性与组织的焊接或交联匹配。

25. 发明授权

US08142423B2 System and method for incising material 有权
标题翻译：切割材料的系统和方法
公开(公告)号：US08142423B2
公开(公告)日：2012-03-27
申请号：US11936635
申请日：2007-11-07
申请人： Ferenc Raksi , Michael Brownell
发明人： Ferenc Raksi , Michael Brownell
IPC分类号： A61F9/01
CPC分类号： A61F9/008 , A61F9/00829 , A61F9/00831 , A61F9/00836 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882 , A61F2009/00897
摘要： Systems and methods of incising a portion of a material include creating a sub-surface separation in a region of the material, and incising a periphery of the region with a pulsed laser beam to produce an edge of the portion. The edge includes a periodically varying shape to secure the portion to the material when the portion is reintegrated. The system includes a laser producing the pulsed laser beam, a scanner operable in response to a control signal, and a controller coupled to the scanner. The controller produces the control signal. In response to the control signal, the scanner creates a sub-surface separation in the region with the pulsed laser beam and incises the periphery of the region with the pulsed laser beam to produce the edge with the periodically varying shape.
摘要翻译：切割材料的一部分的系统和方法包括在材料的区域中产生亚表面分离，以及用脉冲激光束切割该区域的周边以产生该部分的边缘。该边缘包括周期性变化的形状，以便当该部分重新整合时将该部分固定到该材料上。该系统包括产生脉冲激光束的激光器，可响应于控制信号操作的扫描器和耦合到扫描器的控制器。控制器产生控制信号。响应于控制信号，扫描器利用脉冲激光束在该区域中产生子表面间隔，并用脉冲激光束切割该区域的周边以产生具有周期性变化形状的边缘。

26. 发明申请

US20080082088A1 SYSTEM AND METHOD FOR RESECTING CORNEAL TISSUE 审中-公开
标题翻译：用于检查角膜组织的系统和方法
公开(公告)号：US20080082088A1
公开(公告)日：2008-04-03
申请号：US11469941
申请日：2006-09-05
申请人： Ronald M. Kurtz , Gagik Jotyan , Tibor Juhasz , Melvin A. Sarayba
发明人： Ronald M. Kurtz , Gagik Jotyan , Tibor Juhasz , Melvin A. Sarayba
IPC分类号： A61B18/18
CPC分类号： A61F2/142 , A61F9/00831 , A61F9/009 , A61F9/013 , A61F2009/00857 , A61F2009/00872
摘要： A system and method for resecting and transplanting corneal tissue is disclosed. In a recipient cornea, a resection depth from the anterior surface of the recipient cornea is determined based upon a biomechanical model of the recipient cornea. A resection incision for resecting a posterior portion of the recipient cornea is made at the resection depth. Preferably, the incision is made using a surgical laser. Optionally, a contact lens may be placed against the anterior surface of the recipient cornea, wherein the shape of the anterior surface is conformed to the shape of the contact lens.
摘要翻译：公开了一种切割和移植角膜组织的系统和方法。在受体角膜中，根据接受者角膜的生物力学模型确定来自接受者角膜前表面的切除深度。在切除深度处进行切除接受者角膜后部的切除切口。优选地，使用手术激光器进行切口。可选地，隐形眼镜可以抵靠接受者角膜的前表面放置，其中前表面的形状符合隐形眼镜的形状。

27. 发明申请

US20060195076A1 Method and apparatus for patterned plasma-mediated laser trephination of the lens capsule and three dimensional phaco-segmentation 有权
公开(公告)号：US20060195076A1
公开(公告)日：2006-08-31
申请号：US11328970
申请日：2006-01-09
申请人： Mark Blumenkranz , Daniel Palanker , David Mordaunt , Dan Andersen
发明人： Mark Blumenkranz , Daniel Palanker , David Mordaunt , Dan Andersen
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61B18/20 , A61B90/361 , A61B2018/00577 , A61F2/1602 , A61F9/00736 , A61F9/00754 , A61F9/00812 , A61F9/00814 , A61F9/00825 , A61F9/00831 , A61F9/00834 , A61F9/00836 , A61F9/00838 , A61F9/0084 , A61F9/009 , A61F2009/00844 , A61F2009/00851 , A61F2009/00865 , A61F2009/0087 , A61F2009/00878 , A61F2009/00882 , A61F2009/00887 , A61F2009/00889 , A61F2009/00895 , A61F2009/00897
摘要： System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.

28. 发明申请

US20050241653A1 Integrated surgical microscope and wavefront sensor 审中-公开
标题翻译：综合手术显微镜和波前传感器
公开(公告)号：US20050241653A1
公开(公告)日：2005-11-03
申请号：US11110968
申请日：2005-04-20
申请人： Anthony Van Heugten , Daniel Durrie
发明人： Anthony Van Heugten , Daniel Durrie
IPC分类号： A61B3/10 , A61B3/103 , A61B3/13 , A61B18/04 , A61B18/18 , A61B19/00 , A61F2/16 , A61F9/007 , A61F9/01 , A61F9/013
CPC分类号： A61B3/103 , A61B3/1015 , A61B3/13 , A61B90/20 , A61B90/36 , A61F9/007 , A61F9/00736 , A61F9/008 , A61F9/0081 , A61F9/00827 , A61F9/00831 , A61F9/00834 , A61F9/013 , A61F2009/00842 , A61F2009/00848 , A61F2009/00853 , A61F2009/00868 , A61F2009/00872 , A61F2009/00887
摘要： A wavefront sensor is integrated with a surgical microscope for allowing a doctor to make repeated wavefront measurements of a patient's eye while the patient remains on an operating table in the surgical position. The device includes a wavefront sensor optically aligned with a surgical microscope such that their fields of view at least partially overlap. The inclusion of lightweight, compact diffractive optical components in the wavefront sensor allows the integrated device to be supported on a balancing mechanism above a patient's head during a surgical procedure. As a result, the need to reposition the device and/or the patient between measuring optical properties of the eye and performing surgical procedures on the eye is eliminated. Many surgical procedures may be improved or enhanced using the integrated device, including but not limited to cataract surgery, Conductive Keratoplasty, Lasik surgery, and corneal corrective surgery.
摘要翻译：波前传感器与外科手术显微镜集成在一起，允许医生在患者保持在外科手术台的手术台上时对患者的眼睛进行重复的波前测量。该装置包括与手术显微镜光学对准的波前传感器，使得它们的视野至少部分重叠。在波前传感器中包括轻质，致密的衍射光学部件允许在外科手术过程中将集成装置支撑在病人头部上方的平衡机构上。结果，消除了在测量眼睛的光学特性和对眼睛执行外科手术之间重新定位装置和/或患者的需要。使用整合的装置可以改善或增强许多外科手术，包括但不限于白内障手术，导电角膜移植术，Lasik手术和角膜矫正手术。

29. 发明申请

US20050107773A1 Femtosescond laser system for the exact manipulation of material and tissues 有权
标题翻译：用于精确操纵材料和组织的Femtosescond激光系统
公开(公告)号：US20050107773A1
公开(公告)日：2005-05-19
申请号：US10501679
申请日：2003-01-17
申请人： Michael Bergt , Manfred Dick
发明人： Michael Bergt , Manfred Dick
IPC分类号： A61B18/20 , A61F9/007 , B23K26/0622 , B23K26/08 , B23K26/082 , H01S3/00 , A61B18/18
CPC分类号： A61F9/008 , A61F9/00827 , A61F9/00831 , A61F9/00836 , A61F9/0084 , A61F9/009 , A61F2009/00844 , A61F2009/00865 , A61F2009/00868 , A61F2009/0087 , A61F2009/00872 , A61F2009/00874 , A61F2009/00895 , B23K26/0006 , B23K26/04 , B23K26/06 , B23K26/0624 , B23K26/08 , B23K26/082 , B23K2103/32 , H01S3/10046 , H01S3/1103
摘要： A a device for the exact manipulation of material, especially of organic material, includes a pulsed laser system with a radiation source, said radiation source being a cavity-dumped fs oscillator.
摘要翻译：用于精确操作材料，特别是有机材料的装置包括具有辐射源的脉冲激光系统，所述辐射源是空腔倾倒的fs振荡器。

30. 发明授权

US06325792B1 Ophthalmic surgical laser and method 失效
标题翻译：眼科手术激光和方法
公开(公告)号：US06325792B1
公开(公告)日：2001-12-04
申请号：US08287000
申请日：1994-08-08
申请人： Casimir A. Swinger , Shui T. Lai
发明人： Casimir A. Swinger , Shui T. Lai
IPC分类号： A61B1736
CPC分类号： A61F9/00804 , A61B18/26 , A61B2017/00172 , A61B2017/00694 , A61F9/00827 , A61F9/00831 , A61F9/00834 , A61F9/009 , A61F2009/00846 , A61F2009/00863 , A61F2009/0087 , A61F2009/00872 , A61F2009/00874 , A61F2009/00897
摘要： Low energy, ultra-short (femptosecond) pulsed laser radiation is applied to the patient's eye in one of a number of patterns such that the exposed ocular tissue is ablated or excised through the process of optical breakdown or photodisruption in a very controlled fashion. The process can be gentle enough that the invention makes possible the performance of a number of surgical procedures that in the past could not have been performed at all, such as capsulorhexis, or were performed in a fashion that provided less than an ideal result or excessive trauma to the ocular tissue. Such latter applications include the making of incisions for corneal transplantation, radial and arcuate keratotomy, and intrastromal cavitation. Using the laser inside the eye allows the surgeon to perform glaucoma operations such as trabeculoplasty and iridotomy, cataract techniques such as capsulectomy, capsulorhexis and phacoablation, and vitreoretinal surgery, such as membrane resection. The various procedures are accomplished by controlling energy flux or irradiance, geometric deposition of beam exposure and exposure time.
摘要翻译：将低能量，超短（飞秒）脉冲激光辐射以许多图案中的一种施加到患者的眼睛，使得暴露的眼组织以非常受控的方式通过光学破坏或光破坏的过程被消融或切除。该过程可以足够温和，使得本发明使得能够执行过去无法完全执行的诸如撕囊术的多种外科手术，或者以提供小于理想结果或过度的方式进行对眼组织的创伤。这样的后续应用包括形成角膜移植切口，径向和弓形角膜切开术以及胸腔内气蚀。使用眼睛内的激光允许外科医生进行青光眼手术，例如小梁成形术和虹膜切开术，白内障技术，例如囊切除术，撕囊术和超声乳化术，以及玻璃体视网膜手术，例如膜切除术。各种过程通过控制能量通量或辐照度，束曝光和曝光时间的几何沉积来实现。

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