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1. 发明公开

US20230181369A1 OPHTHALMIC SURGERY APPARATUS 审中-公开
公开(公告)号：US20230181369A1
公开(公告)日：2023-06-15
申请号：US17995560
申请日：2021-04-06
申请人： UNIVERSITE DE BORDEAUX , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS , CENTRE HOSPITALIER UNIVERSITAIRE DE BORDEAUX , CENTRE TECHNOLOGIQUE ALPHANOV
发明人： John LOPEZ , Donetsi IRIBARREN , Bruno CHASSAGNE , David TOUBOUL
IPC分类号： A61F9/008 , A61B90/00
CPC分类号： A61F9/0084 , A61F9/00827 , A61F9/00831 , A61B90/361 , A61F2009/0087 , A61F2009/00872 , A61F2009/00897 , A61B2017/0019
摘要： The disclosure relates to an ophthalmic surgery apparatus for making an incision in ocular biological tissue such as a cornea or a crystalline lens. The apparatus includes: a laser source suitable for delivering a beam of laser pulses; an optical focusing system for focusing the beam of laser pulses on a focal point in the ocular biological tissue; an optical system for moving the beam of laser pulses, configured to move the focal point along a predetermined three-dimensional trajectory; a control unit configured to control the laser source, and the optical system for moving the beam of laser pulses, in such a way that the parameters of the beam of laser pulses and the parameters of the optical system for moving the beam of laser pulses are adjusted according to the position of the focal point in the trajectory during the incision.

2. 发明授权

US10076445B2 Posterio capsulotomy using laser techniques 有权
公开(公告)号：US10076445B2
公开(公告)日：2018-09-18
申请号：US14412168
申请日：2013-03-14
申请人： BAUSCH & LOMB INCORPORATED , TECHNOLAS PERFECT VISION GMBH
发明人： David Haydn Mordaunt , Frieder Loesel , Gwillem Mosedale
IPC分类号： A61F9/008 , A61F2/16
CPC分类号： A61F9/00834 , A61F2/1662 , A61F9/0081 , A61F9/00831 , A61F9/0084 , A61F2009/00851 , A61F2009/0087 , A61F2009/00889
摘要： A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.

3. 发明授权

US09844463B2 Ophthalmic laser apparatus, system, and method with high resolution imaging 有权
公开(公告)号：US09844463B2
公开(公告)日：2017-12-19
申请号：US12416355
申请日：2009-04-01
申请人： Keith Watanabe , Jesse Buck , Guy V. Holland , Michael Brownell , Valentina Doushkina
发明人： Keith Watanabe , Jesse Buck , Guy V. Holland , Michael Brownell , Valentina Doushkina
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00827 , A61F9/00829 , A61F9/00831 , A61F9/00834 , A61F9/00836 , A61F2009/00844 , A61F2009/00846 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882
摘要： System and method of photoaltering a region of an eye using a high resolution digital image of the eye. The system includes a laser assembly for outputting a pulsed laser beam, an imaging system for capturing a real-time high resolution digital image of the eye and displaying the digital image of the eye, a user interface receiving at least one laser parameter input, and a controller coupled to the laser assembly, imaging system, and user interface. The controller directs the laser assembly to output the pulsed laser beam to the region of the eye based on the laser parameter input.

4. 发明申请

US20170246033A1 OPHTHALMIC RANGE FINDING 审中-公开
公开(公告)号：US20170246033A1
公开(公告)日：2017-08-31
申请号：US15461388
申请日：2017-03-16
申请人： AMO DEVELOPMENT, LLC
发明人： Zsolt Bor , John Tamkin
IPC分类号： A61F9/008
CPC分类号： A61F9/0084 , A61B3/10 , A61B3/1225 , A61B3/14 , A61F9/008 , A61F9/00831 , A61F2009/00844 , A61F2009/0087 , A61F2009/00872 , A61F2009/00878 , A61F2009/00889
摘要： Embodiments of the invention provide methods and systems for analyzing the ophthalmic anatomy of a patient posterior to the cornea. The method may include scanning a focus of a femtosecond laser beam along a path within the patient's eye. A portion of the path may be disposed posterior to the patient's cornea. The method may also include acquiring a first reflectance image and a second reflectance image associated with the focus disposed respectively at a first location of the path and a second location of the path. The method may further include determining the presence or absence of an ophthalmic anatomical feature of the eye based on a comparison between the first reflectance image and the second reflectance image.

5. 发明授权

US09693903B2 Apparatus for patterned plasma-mediated laser ophthalmic surgery 有权
公开(公告)号：US09693903B2
公开(公告)日：2017-07-04
申请号：US15236284
申请日：2016-08-12
申请人： OPTIMEDICA CORPORATION
发明人： Daniel V. Palanker , Mark S. Blumenkranz , David H. Mordaunt , Dan E. Andersen
IPC分类号： A61B18/18 , A61F9/008 , A61F9/007 , A61F9/009 , A61B18/20 , A61F2/16 , A61B90/00 , A61B18/00
CPC分类号： A61F9/008 , A61B18/20 , A61B90/361 , A61B2018/00577 , A61F2/1602 , A61F9/00736 , A61F9/00754 , A61F9/00812 , A61F9/00814 , A61F9/00825 , A61F9/00831 , A61F9/00834 , A61F9/00836 , A61F9/00838 , A61F9/0084 , A61F9/009 , A61F2009/00844 , A61F2009/00851 , A61F2009/00865 , A61F2009/0087 , A61F2009/00878 , A61F2009/00882 , A61F2009/00887 , A61F2009/00889 , A61F2009/00895 , A61F2009/00897
摘要： A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

6. 发明授权

US09411938B2 System for defining cuts in eye tissue 有权
标题翻译：用于定义眼组织切割的系统
公开(公告)号：US09411938B2
公开(公告)日：2016-08-09
申请号：US12731573
申请日：2010-03-25
申请人： Christian Rathjen
发明人： Christian Rathjen
IPC分类号： A61F9/008 , G06F19/00
CPC分类号： G06F19/3437 , A61F9/00827 , A61F9/00831 , A61F9/00836 , A61F2009/00853 , A61F2009/00863 , A61F2009/00865 , A61F2009/0087 , A61F2009/00872 , A61F2009/00897 , G06F19/00 , G06F19/3481 , G16H50/50
摘要： A computer-aided system include a data storage (18) with eye data (181), which defines a three-dimensional model of the eye, and a reference generator (113) for defining and storing a geometric reference in relation to the three-dimensional model of the eye. The system additionally includes a cut surface editor for defining and positioning cut surfaces in the three-dimensional model of the eye based on user instructions. Finally, the system includes a cut pattern generator (117) for, based on the positioned cut surfaces, generating and storing three-dimensional cut patterns for defining tissue cuts to be executed in a human eye by means of femtosecond laser pulses. The generation of a three-dimensional cut pattern permits the user to define tissue cuts made possible by femtosecond laser pulses in a targeted and efficient fashion in the three-dimensional model of the eye without having to undertake manipulations directly on the eye for this purpose.
摘要翻译：计算机辅助系统包括具有定义眼睛的三维模型的眼睛数据（181）的数据存储器（18），以及用于定义和存储关于三维图形的几何参考的参考生成器（113）眼睛的三维模型。该系统还包括切割表面编辑器，用于基于用户指令在眼睛的三维模型中定义和定位切割表面。最后，系统包括用于基于定位的切割表面的切割图案生成器（117），其通过飞秒激光脉冲生成和存储用于定义要在人眼中执行的组织切割的三维切割图案。三维切割图案的产生允许用户在眼睛的三维模型中以目标和有效的方式定义可能由飞秒激光脉冲产生的组织切割，而不必为此目的直接对眼睛进行操作。

7. 发明申请

US20160030243A1 TECHNIQUE FOR LASER-CUTTING AN ENDOTHELIAL CORNEAL GRAFT 审中-公开
标题翻译：激光切割内皮角膜的技术
公开(公告)号：US20160030243A1
公开(公告)日：2016-02-04
申请号：US14440591
申请日：2013-10-28
申请人： WAVELIGHT GMBH
发明人： Christof DONITZKY , Theo SEILER
IPC分类号： A61F9/008
CPC分类号： A61F9/00831 , A61F2009/00853
摘要： A method for preparing an endothelial corneal graft is provided. The method comprises: providing a donor cornea; irradiating the donor cornea from an endothelial side thereof with laser radiation to cause a photodisruption in tissue of the donor cornea at a focal point of the radiation; and moving the focal point of the radiation to form an endothelial graft in the donor cornea. By irradiating the donor cornea from the endothelial side thereof, instead of the epithelial side, to cut the endothelial graft, optical inhomogeneities which may develop after death in stromal tissue of the donor cornea leave the laser cutting process substantially unaffected.
摘要翻译：提供了一种制备内皮角膜移植物的方法。该方法包括：提供供体角膜; 用激光辐射从其内皮侧照射供体角膜，以在辐射的焦点处引起供体角膜的组织中的光中断; 并移动辐射的焦点以在供体角膜中形成内皮移植物。通过从其内皮侧的供体角膜而不是上皮侧照射供体角膜来切割内皮移植物，在供体角膜的基质组织中死亡后可能发展的光学不均匀性使激光切割过程基本上不受影响。

8. 发明申请

US20150265397A1 METHOD FOR TRANSPLANTING A PART OF THE CORNEA AND A SURGICAL MICROSCOPE THEREFOR 审中-公开
标题翻译：用于转运角膜的一部分及其手术显微镜的方法
公开(公告)号：US20150265397A1
公开(公告)日：2015-09-24
申请号：US14666129
申请日：2015-03-23
申请人： Carl Zeiss Meditec AG
发明人： Christoph Hauger , Joachim Steffen
IPC分类号： A61F2/14 , A61F9/008
CPC分类号： A61F2/145 , A61F9/00831 , A61F2009/00872
摘要： A method for transplanting an endothelial-layer/descemet-layer from a donor organ to a receiver organ include: staining the endothelial-layer/descemet-layer blue in both the donor organ and the receiver organ; making respective incisions of the same diameter into the endothelial-layer/descemet-layer in both the donor organ and the receiver organ using a yellow laser light; preparing the endothelial-layer/descemet-layer from the donor organ and removing the endothelial-layer/descemet-layer within the in particular circular cut in the receiver organ; and, inserting the donor preparation, more particularly circular donor preparation, into the corresponding cutout in the receiver organ. A correspondingly configured surgical microscope is provided.
摘要翻译：从供体器官移植到受体器官的内皮层/破裂层的方法包括：在供体器官和受体器官中染色内皮层/去皮层蓝色; 使用黄色激光将相同直径的相应切口制成供体器官和受体器官内的内皮层/脱皮层; 从供体器官制备内皮层/去皮层，并去除受体器官中特别是圆形切口内的内皮层/破裂层; 并且将供体制剂，更特别是圆形的供体制剂插入受体器官的相应切口中。提供相应配置的手术显微镜。

9. 发明申请

US20150141968A1 Method and Apparatus for Patterned Plasma-Mediated Laser Trephination of the Lens Capsule and Three Dimensional Phaco-Segmentation 有权
标题翻译：用于图案化等离子体介导的镜片胶囊激光治疗和三维Phaco分割的方法和装置
公开(公告)号：US20150141968A1
公开(公告)日：2015-05-21
申请号：US14516830
申请日：2014-10-17
申请人： OptiMedica Corporation
发明人： Mark S. Blumenkranz , Daniel V. Palanker , David H. Mordaunt , Dan E. Andersen
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61B18/20 , A61B90/361 , A61B2018/00577 , A61F2/1602 , A61F9/00736 , A61F9/00754 , A61F9/00812 , A61F9/00814 , A61F9/00825 , A61F9/00831 , A61F9/00834 , A61F9/00836 , A61F9/00838 , A61F9/0084 , A61F9/009 , A61F2009/00844 , A61F2009/00851 , A61F2009/00865 , A61F2009/0087 , A61F2009/00878 , A61F2009/00882 , A61F2009/00887 , A61F2009/00889 , A61F2009/00895 , A61F2009/00897
摘要： System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.
摘要翻译：用于在不同深度进行眼组织切口的系统和方法。该系统和方法聚焦在眼睛组织内各种深度的各种焦点上，可能是模式。分段镜头可用于同时创建多个焦点。可以通过顺序或同时聚焦不同深度的光来实现最佳切口，产生扩张的等离子体柱，并且产生具有细长腰部的光束。

10. 发明申请

US20140228827A1 METHOD AND APPARATUS FOR PATTERNED PLASMA-MEDIATED LASER TREPHINATION OF THE LENS CAPSULE AND THREE DIMENSIONAL PHACO-SEGMENTATION 有权
标题翻译：用于图案等离子体介质激光照射镜片胶囊和三维PHACO分段的方法和装置
公开(公告)号：US20140228827A1
公开(公告)日：2014-08-14
申请号：US14184082
申请日：2014-02-19
申请人： OptiMedica Corporation
发明人： Mark S. Blumenkranz , Daniel V. Palanker , David H. Mordaunt , Dan E. Andersen
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61B18/20 , A61B90/361 , A61B2018/00577 , A61F2/1602 , A61F9/00736 , A61F9/00754 , A61F9/00812 , A61F9/00814 , A61F9/00825 , A61F9/00831 , A61F9/00834 , A61F9/00836 , A61F9/00838 , A61F9/0084 , A61F9/009 , A61F2009/00844 , A61F2009/00851 , A61F2009/00865 , A61F2009/0087 , A61F2009/00878 , A61F2009/00882 , A61F2009/00887 , A61F2009/00889 , A61F2009/00895 , A61F2009/00897
摘要： System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.
摘要翻译：用于在不同深度进行眼组织切口的系统和方法。该系统和方法聚焦在眼睛组织内各种深度的各种焦点上，可能是模式。分段镜头可用于同时创建多个焦点。可以通过顺序或同时聚焦不同深度的光来实现最佳切口，产生扩张的等离子体柱，并且产生具有细长腰部的光束。

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