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21. 发明申请

US20060200068A1 Novel enhanced microburst ultrasonic power delivery system and method 有权
标题翻译：新型增强型微爆超声功率输送系统及方法
公开(公告)号：US20060200068A1
公开(公告)日：2006-09-07
申请号：US11415730
申请日：2006-05-01
申请人： Kenneth Kadziauskas , Paul Rockley
发明人： Kenneth Kadziauskas , Paul Rockley
IPC分类号： A61B17/20 , A61B18/18
CPC分类号： A61F9/00745 , A61B2017/00176 , A61B2017/00194 , A61B2018/00666 , B06B1/023 , B06B1/0253 , B06B2201/76
摘要： A method and apparatus for delivering energy during a surgical procedure such as phacoemulsification is provided. The method and apparatus include applying energy during at least one pulsed energy on period, comprising applying energy during a series of short burst periods, the short burst periods interspersed by short rest periods. The method and apparatus further comprise delivering minimal energy during a long off period, the long off period comprising a relatively long period when minimal energy is applied, wherein one long off period follows each pulsed energy on period. The short burst periods and the short rest periods are relatively brief in duration as compared with the long off period.
摘要翻译：提供了一种在诸如晶状体乳化之类的外科手术过程中递送能量的方法和装置。所述方法和装置包括在至少一个脉冲能量打开周期期间施加能量，包括在一连串的短脉冲串周期期间施加能量，所述短脉冲串周期在短暂的休息时间间隔散布。所述方法和装置还包括在长时间关闭期间递送最小能量，所述长时间关闭周期包括在施加最小能量时相对较长的周期，其中一个长时间段在每个脉冲能量周期之后。短时间短暂休息时间与长时间相比持续时间相对较短。

22. 发明申请

US20030009157A1 FLEXIBLE FLOW APPARATUS AND METHOD FOR THE DISRUPTION OF OCCLUSIONS 失效
标题翻译：柔性流动装置及其破坏方法
公开(公告)号：US20030009157A1
公开(公告)日：2003-01-09
申请号：US09328514
申请日：1999-06-09
发明人： MARC-ALAN LEVINE , EDUARDO U. SUCGANG , STEPHEN J. HEBERT , ESTELA D. GATCHALIAN , QUANG Q. TRAN , VICTOR C. ESCH
IPC分类号： A61B018/24 , A61B018/26
CPC分类号： A61B18/26 , A61B18/245 , A61B2017/00176 , A61B2018/2211
摘要： The invention encompasses methods and flexible apparatus for creating fluid flow from one location to another through the repetitive expansion and collapse of bubbles generated as a result of the absorption of repetitive pulses of radiation in a fluid. This pumping phenomenon can be used to aid removal of a total or partial occlusion in a body passage by disrupting the surface of the occlusion with acoustic shock and pressure waves and/or by causing mechanical disruption of the occlusive material. Flexibility is improved with choice of materials and particular constructions.
摘要翻译：本发明包括用于通过由于在流体中吸收重复的辐射脉冲而产生的气泡的重复膨胀和塌缩来产生从一个位置到另一个位置的流体流动的方法和柔性装置。这种抽吸现象可以用于通过用声波冲击和压力波破坏闭塞表面和/或通过引起封闭材料的机械破坏来去除身体通道中的全部或部分闭塞。通过选择材料和特定结构可以提高灵活性。

23. 发明授权

US06214034B1 Method of selective photothermolysis 失效
标题翻译：选择性光热解方法
公开(公告)号：US06214034B1
公开(公告)日：2001-04-10
申请号：US09076098
申请日：1998-05-12
申请人： Zion Azar
发明人： Zion Azar
IPC分类号： A61N3300
CPC分类号： A61B18/203 , A61B18/18 , A61B18/20 , A61B2017/00057 , A61B2017/00084 , A61B2017/00154 , A61B2017/00176 , A61B2017/00756 , A61B2017/308 , A61B2018/00005 , A61B2018/00452 , A61B2018/00458 , A61B2018/1807 , A61B2218/006 , A61B2218/008
摘要： A method and apparatus for selective photothermolysis of a target tissue within surrounding tissue. The target and the surrounding tissue are heated to a predetermined temperature of about 60° C. by a pulsed heat source such as a flash lamp which creates a temperature gradient in the air included in a cavity formed between the housing of the apparatus and the surrounding tissue. The surface temperature of the tissue is monitored by a sensor unit. When the tissue surface reaches the predetermined temperature the target tissue is heated to the point of coagulation, preferably by narrow band electromagnetic radiation. The temperature difference between the coagulating target and the surrounding tissue is sufficiently mild that heat diffusing out of the target does not damage the surrounding tissue, even in the case of a relatively large target such as varicose veins. The heating action may be terminated by automatically pumping air or another suitable coolant into the cavity when the surface of the tissue reaches a preset value or by lifting the apparatus off the tissue. The apparatus may include a programmable controller which may be programmed locally or remotely with the treatment parameters.
摘要翻译：用于对周围组织内的靶组织进行选择性光热解的方法和装置。通过脉冲热源（例如闪光灯）将目标和周围组织加热至约60℃的预定温度，该闪光灯在包含在设备的壳体和周围的空腔中的空气中产生温度梯度组织。组织的表面温度由传感器单元监测。当组织表面达到预定温度时，目标组织被加热到凝固点，优选地通过窄带电磁辐射。凝固对象和周围组织之间的温差足够温和，即使在诸如静脉曲张之类的较大目标的情况下，扩散到靶外的热也不会损伤周围的组织。当组织的表面达到预设值或通过将设备从组织提起时，自动地将空气或另一合适的冷却剂泵送到腔中来终止加热动作。该装置可以包括可编程控制器，其可以使用治疗参数在本地或远程编程。

24. 发明授权

US06210400B1 Flexible flow apparatus and method for the disruption of occlusions 失效
标题翻译：柔性流动装置和堵塞方法
公开(公告)号：US06210400B1
公开(公告)日：2001-04-03
申请号：US09165435
申请日：1998-10-02
申请人： Stephen J. Hebert , Marc-Alan Levine , Eduardo U. Sucgang , Quang Q. Tran , Victor C. Esch
发明人： Stephen J. Hebert , Marc-Alan Levine , Eduardo U. Sucgang , Quang Q. Tran , Victor C. Esch
IPC分类号： A61B1818
CPC分类号： A61B18/26 , A61B18/245 , A61B2017/00176 , A61B2018/2211
摘要： Apparatus for pumping fluid from one location to another via generation of bubbles in fluid, and expansion and callapse thereof, are described. These apparatus deliver repetitive pulses of radiation to a fluid to form bubbles therein. The expansion and collapse of the bubbles cause fluid motion or pumping. This pumping can be used to facilitate removal of a total or partial occlusion in a body passage by a variety of mechanisms. The apparatus are flexible to facilitate use within a body passage.
摘要翻译：描述了用于通过在流体中产生气泡将流体从一个位置泵送到另一个位置的装置，以及其膨胀和回收。这些装置将重复的辐射脉冲输送到流体以在其中形成气泡。气泡的膨胀和破裂会导致流体运动或泵送。这种泵送可以用于通过各种机制促进身体通道中的全部或部分闭塞的去除。该装置是灵活的，以便于在身体通道内使用。

25. 发明授权

US5993441A Control of photorefractive keratectomy 失效
$Control of photorefractive keratectomy$
标题翻译：控制光折射角膜切除术
公开(公告)号：US5993441A
公开(公告)日：1999-11-30
申请号：US695673
申请日：1996-08-08
申请人： David F. Muller , Alex C. Sacharoff , Peter J. Klopotek
发明人： David F. Muller , Alex C. Sacharoff , Peter J. Klopotek
IPC分类号： A61B17/00 , A61B19/00 , A61F9/01 , A61N5/06
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00808 , A61B2017/00017 , A61B2017/00176 , A61B2017/00181 , A61B2017/00194 , A61B90/30 , A61F2009/00844 , A61F2009/00848 , A61F2009/00872 , A61F2009/00895
摘要： A method and system are described for performing photorefractive keratectomy procedure employing pulses of photoablative radiation to selectively ablate corneal tissue of a patient's eye in an ablation zone on the anterior corneal surface to produce a desired refractive correction in the corneal tissue. The method and system employ control of the effect of ocular fluid at the corneal surface so as to reduce the disturbance of such fluid on the desired ablation process while maintaining hydration of the corneal tissue. Controlling the average repetition rate of the radiation pulses applied to the corneal surface so as to reduce intrapulse fluid accumulation at the corneal surface without dehydrating the corneal tissue, selecting an increased fluence level of the pulse applied to the corneal surface to reduce the effect of fluid accumulation at the corneal surface, and applying evaporative energy to the site of incidence of a pulse of an ablative beam prior to incidence of said pulse at said site are shown as ways to effect this control. Application of the new method and system to wide area ablation techniques and to scanning techniques are described Reduction of irregularities when ablating large areas, e.g., grater than 5.5 cm is made possible in either case.
摘要翻译：描述了一种用于进行光折射角膜切除术的方法和系统，其使用光消融辐射的脉冲来选择性地在前角膜表面上的消融区域中烧蚀患者眼睛的角膜组织，以在角膜组织中产生期望的屈光矫正。该方法和系统采用对角膜表面上的眼液的影响的控制，以便在保持角膜组织的水合作用的同时减少所需消融过程中的这种流体的干扰。控制施加到角膜表面的辐射脉冲的平均重复率，以减少角膜表面的脉冲内液体积聚，而不会使角膜组织脱水，选择施加到角膜表面的脉冲的增加的注量水平以减少流体的影响在所述位置处的所述脉冲入射之前，在角膜表面积聚并将蒸发能量施加到烧蚀光束的脉冲的入射部位被示出为实现该控制的方式。描述了将新方法和系统应用于广域消融技术和扫描技术的描述。在任何一种情况下，当切割大面积（例如，大于5.5cm）时，减少不规则性成为可能。

26. 发明授权

US5246436A Midinfrared laser tissue ablater 失效
标题翻译：紫外激光组织放大镜
公开(公告)号：US5246436A
公开(公告)日：1993-09-21
申请号：US810742
申请日：1991-12-18
申请人： T. Scott Rowe
发明人： T. Scott Rowe
IPC分类号： A61B17/00 , A61B17/22 , A61B17/34 , A61B18/22 , A61F9/011 , A61M1/00
CPC分类号： A61F9/00802 , A61B17/3421 , A61B2017/00168 , A61B2017/00176 , A61B2017/22007 , A61B2017/22008 , A61B2018/2272 , A61F2009/00863
摘要： A midinfrared laser tissue ablater having an Er:YAG radiation source optically connected to a first end of a fiber optic cable, a probe with a handle and a bifurcated cannula having a first half and a second half and a generally closed, hollow tip having an opening opposite the handle, a fiber optic integrally and coaxially mounted in the probe, optically and mechanically connected to a second end of the fiber optic cable and terminating at a free end in an interior of the hollow tip, the free end having a coating with a hole so that a pulse of radiation emitted by the radiation source is directed through the fiber optic cable and the fiber optic to the free end where the pulse of radiation is reflected by the coating out the hole in the coating and into the opening in the tip, an irrigation source connected to the first half of the cannula and an aspiration source connected to the second half of the cannula.
摘要翻译：具有与光纤电缆的第一端光学连接的Er：YAG辐射源的紫外激光组织放大器，具有手柄的探针和具有第一半和第二半部以及大致封闭的中空尖端的分叉插管，所述中空尖端具有与手柄相对地开口，光纤整体地并且同轴地安装在探针中，光学和机械地连接到光纤电缆的第二端并终止在中空尖端的内部的自由端，自由端具有涂层一个孔，使得由辐射源发射的辐射的脉冲被引导通过光纤电缆和光纤到自由端，其中辐射脉冲被涂层反射出来，并穿过涂层中的孔尖端，连接到套管的前半部的灌溉源和连接到插管的第二半部的抽吸源。

27. 发明公开

US20240339993A1 SYNERGISTIC PULSE GENERATION APPARATUS, DEVICE AND METHOD 审中-公开
公开(公告)号：US20240339993A1
公开(公告)日：2024-10-10
申请号：US18681822
申请日：2022-08-11
申请人： HANGZHOU WKNIFE MEDICAL TECHNOLOGY CO., LTD
发明人： Xinghua ZHONG , Long WANG , Ke YANG
IPC分类号： H03K3/53 , A61B17/00 , A61B18/00 , A61B18/12 , H03K3/42
CPC分类号： H03K3/53 , A61B18/1206 , H03K3/42 , A61B2017/00176 , A61B2018/00577
摘要： Embodiments of the present application provide a cooperative pulse generation apparatus, device and generation method. The synergistic pulse generation apparatus comprises a drive circuit and a pulse generation circuit. The drive circuit receives a first control signal and a second control signal sent by a host computer, converts the first control signal into a first drive signal, and converts the second control signal into a second drive signal. The pulse generation circuit comprises a first power supply, a second power supply, a first pulse generation module, and a second pulse generation module. The first pulse generation module stores electric energy supplied by the first power supply and discharges the electricity under the control of the first drive signal to form a first pulse signal, and the second pulse generation module stores electric energy provided by the second power supply and discharges the electricity under the control of the second drive signal to form a second pulse signal. The present embodiment can selectively form a first pulse signal and/or a second pulse signal having different widths, thereby achieving the purpose of applying a composite pulse to a load.

28. 发明授权

US11896300B2 Tailored laser pulses for surgical applications 有权
公开(公告)号：US11896300B2
公开(公告)日：2024-02-13
申请号：US17121815
申请日：2020-12-15
申请人： Boston Scientific Scimed, Inc.
发明人： Werner Falkenstein , Michael Schubert , Stephan Dittmar , Anna Butsch , Thomas Kremser
IPC分类号： A61B18/20 , A61B18/26 , H01S3/10 , H01S3/102 , A61B18/22 , A61B18/00 , A61B18/24 , A61B17/00 , H01S3/042 , H01S3/16 , H01S3/131 , H01S3/04 , H01S3/093
CPC分类号： A61B18/20 , A61B18/26 , H01S3/1024 , H01S3/10038 , A61B18/245 , A61B2017/00176 , A61B2018/0066 , A61B2018/00642 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/205545 , A61B2018/2261 , A61B2018/2277 , H01S3/042 , H01S3/0407 , H01S3/093 , H01S3/1312 , H01S3/1616 , H01S3/1643
摘要： A laser system may include a controller configured to direct a plurality of temporally spaced-apart electrical pulses to a device that optically pumps a lasing medium, and a lasing medium configured to output a quasi-continuous laser pulse in response to the optical pumping. The plurality of temporally spaced-apart electrical pulses may include (a) a first electrical pulse configured to excite the lasing medium to an energy level below a lasing threshold of the lasing medium, and (b) multiple second electrical pulses following the first electrical pulse. The quasi-continuous laser pulse is output in response to the multiple second electrical pulses.

30. 发明申请

US20180078310A1 Method and apparatus for dual-wavelength laser treatment 审中-公开
公开(公告)号：US20180078310A1
公开(公告)日：2018-03-22
申请号：US15705693
申请日：2017-09-15
申请人： Boston Scientific Scimed, Inc.
发明人： Rongwei Jason XUAN , Edouard A. KOULLICK , Thomas HASENBERG , Jieun HWANG , Hyejin KIM , Hanjae PYO , Hyun Wook KANG , Jason GONG , Xirong YANG , Honggang YU
IPC分类号： A61B18/20
CPC分类号： A61B18/20 , A61B18/203 , A61B2017/00176 , A61B2018/00547 , A61B2018/00589 , A61B2018/00601 , A61B2018/00625 , A61B2018/00702 , A61B2018/207
摘要： A laser system may include a first laser source configured to output a first laser energy at a first wavelength, a second laser source configured to output a second laser energy at a second wavelength, and a combiner configured to receive the first and second laser energies and output a dual-wavelength laser energy. The first and second wavelengths are different, and first and second laser energies are output simultaneously. Related systems and methods are also disclosed.

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