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21. 发明授权

US11298386B2 Drug composition for angiogenesis therapy 有权
公开(公告)号：US11298386B2
公开(公告)日：2022-04-12
申请号：US16373388
申请日：2019-04-02
申请人： Tadashi Tanabe , Keiichi Hukuda , Takashi Kawakami
发明人： Tadashi Tanabe , Keiichi Hukuda , Takashi Kawakami
IPC分类号： A61K35/76 , A61K31/5585 , A61K38/18 , A61K38/52 , A61K45/06 , A61K48/00 , C12N7/00 , A61K35/13
摘要： Drug compositions of angiogenesis therapy contain gene coding for human prostacyclin synthase (hPGIS) synthesizing prostaglandin I2 with activities of vasodialation and/or anti-platelet aggregation; drug compositions contain adeno-associated virus (AAV) inserted with gene for angiogenesis factors. The administration of the drug compositions into the aimed treatment region results in transfer of AAV type 1-hPGIS to skeletal muscles and induces a notable expression of human PGIS gene in skeletal muscles. The PGI2 is produced by mediation of the gene expression in the muscle cells, secreted, induces vessel-protective, neovascularization and anti-platelet aggregation actions, which lead to an improvement in vascular ischemia.

22. 发明授权

US08597212B2 Wrist assisting apparatus 失效
标题翻译：手腕辅助装置
公开(公告)号：US08597212B2
公开(公告)日：2013-12-03
申请号：US12755651
申请日：2010-04-07
申请人： Takashi Kawakami , Toshihiko Ishiko , Keisuke Ueda
发明人： Takashi Kawakami , Toshihiko Ishiko , Keisuke Ueda
IPC分类号： A61F5/00
CPC分类号： A61F5/013 , A61F4/00
摘要： A wrist assisting apparatus can smoothly bend and stretch a joint even if a turning shaft of a joint and a rotation shaft of a wearing tool are deviated from each other. Also, an excessive load is not applied to a user. The wrist assisting apparatus of the present invention includes a palm support member for supporting a hand, angle changing members connected to sides of the palm support member, a front arm wearing tool disposed along the front arm, and joint members for forming a rotation shaft of the angle changing member with respect to the front arm wearing tool, wherein the angle changing members are provided on both sides of the palm support member, the joint members are provided on the angle changing members, respectively, and the joint members are located on both sides of a wrist.
摘要翻译：即使关节的转动轴和磨损工具的旋转轴彼此偏离，手腕辅助装置也能平滑地弯曲和拉伸关节。而且，不会对用户施加过大的负荷。本发明的手腕辅助装置包括用于支撑手的手掌支撑构件，连接到手掌支撑构件的侧面的角度改变构件，沿着前臂设置的前臂佩戴工具，以及用于形成旋转轴的旋转轴的接合构件所述角度改变构件相对于所述前臂佩戴工具，其中所述角度改变构件设置在所述手掌支撑构件的两侧，所述接合构件分别设置在所述角度改变构件上，并且所述接合构件位于两者上手腕的两侧。

23. 发明授权

US08256014B2 Content processing device, server device, communication method, and storage medium containing computer program 失效
标题翻译：内容处理装置，服务器装置，通信方式以及包含计算机程序的存储介质
公开(公告)号：US08256014B2
公开(公告)日：2012-08-28
申请号：US12067293
申请日：2006-09-29
申请人： Takayuki Kori , Takashi Kawakami , Susumu Takatsuka , Hideo Tsukazaki , Kotaro Asaka
发明人： Takayuki Kori , Takashi Kawakami , Susumu Takatsuka , Hideo Tsukazaki , Kotaro Asaka
IPC分类号： G06F7/04 , G06F21/00 , H04J3/16 , G06F21/24 , G11B20/10
CPC分类号： G06F21/10
摘要： When a PC 10 connects to a PD 20, the PC 10 decides whether or not the PD 20 holds a group ID and if the PC 10 decides PD 20 holds the group ID, PC 10 decides whether or not the group ID held in the PC 10 and the group ID held in the PD 20 coincide with each other. If the both IDs are not decided that they don't coincide with each other, the PC 10 acquires a device ID corresponding to PD 20 from PD 20 and transfers the device ID and a terminal ID of the PC 10 to a server apparatus 32. Then the PC 10 receives, from the server apparatus 32, a user link completion information representative that an association between first user ID corresponding to the terminal ID and second user ID corresponding to the device ID is completed.
摘要翻译：当PC 10连接到PD 20时，PC 10判定PD20是否保持组ID，PC10决定PD20保持组ID，PC10判断PC中保持的组ID 并且保持在PD20中的组ID彼此一致。如果这两个ID未被确定为不一致，则PC 10从PD 20获取与PD20相对应的设备ID，并将PC10的设备ID和终端ID传送到服务器设备32。然后，PC 10从服务器装置32接收表示与终端ID对应的第一用户ID与对应于设备ID的第二用户ID之间的关联完成的用户链接完成信息。

24. 发明授权

US08180731B2 Apparatus and method for computing evaluation values of content data stored for reproduction 有权
标题翻译：用于计算存储用于再现的内容数据的评估值的装置和方法
公开(公告)号：US08180731B2
公开(公告)日：2012-05-15
申请号：US11492116
申请日：2006-07-25
申请人： Tatsuya Konno , Susumu Takatsuka , Hideo Tsukazaki , Takashi Kinouchi , Kotaro Asaka , Takashi Kawakami , Yasuharu Seki
发明人： Tatsuya Konno , Susumu Takatsuka , Hideo Tsukazaki , Takashi Kinouchi , Kotaro Asaka , Takashi Kawakami , Yasuharu Seki
IPC分类号： G06F7/00 , G06F17/00 , G06F13/14
CPC分类号： G06F17/30038
摘要： An information-processing apparatus, reproduction apparatus, communication method and computer program are disclosed wherein an evaluation value can be added automatically to contents stored in a storage apparatus or medium. The information-processing apparatus comprising an acquisition section which acquires, from a portable reproduction apparatus which is capable of reproducing contents data, reproduction history information of the contents data in the portable reproduction apparatus. An evaluation value arithmetic operation section arithmetically operates a computed evaluation value corresponding to the content data based on the reproduction history information acquired by the acquisition section. A transfer section transfers the computed evaluation value arithmetically operated by the evaluation value arithmetic operation section to the portable reproduction apparatus.
摘要翻译：公开了一种信息处理装置，再现装置，通信方法和计算机程序，其中评估值可以自动地添加到存储在存储装置或介质中的内容。所述信息处理装置包括：获取部，其从能够再现内容数据的便携式再现装置获取所述便携式再现装置中的内容数据的再现历史信息。评估值算术运算部根据由获取部获取的再现历史信息，算出与内容数据对应的计算出的评价值。传送部将由评估值算术运算部算术运算的计算评价值传送到便携式再现装置。

25. 发明授权

US08012330B2 Plating method and plating apparatus 有权
标题翻译：电镀方法和电镀装置
公开(公告)号：US08012330B2
公开(公告)日：2011-09-06
申请号：US12071679
申请日：2008-02-25
申请人： Takashi Kawakami , Tsutomu Nakada
发明人： Takashi Kawakami , Tsutomu Nakada
IPC分类号： C25D5/00 , C25D5/02 , C25D7/12 , C25D5/20 , B23H11/00
CPC分类号： C25D17/008 , C25D5/02 , C25D17/004 , C25D21/02 , Y10S134/902
摘要： A plating method, employing a face-down manner of plating and using a resistor body between a substrate and an anode, can securely bring an entire surface to be plated of the substrate into contact with a plating solution without permitting intrusion of air bubbles to the surface to be plated. A resistor body is disposed above the anode and immersed in the plating solution, allowing the plating solution to flow along an upper surface of the resistor body from the periphery toward the center of the resistor body. Thus, a raised portion of the plating solution is created in the center of the upper surface of the resistor body. The substrate is then lowered with the surface facing downwardly so as to fill the space between the surface to be plated of the substrate and the upper surface of the resistor body with the plating solution.
摘要翻译：在基板和阳极之间采用正面朝下的电镀方式和使用电阻体的电镀方法可以牢固地使整个基板的镀覆表面与镀液接触而不允许气泡侵入到待镀面电阻体设置在阳极的上方，浸在电解液中，使得电镀液从电阻体的周边朝向电阻体的中心流动。因此，在电阻体的上表面的中央形成电镀液的隆起部。然后将表面朝下放置基板，以便用电镀液填充基板的被镀表面和电阻体的上表面之间的空间。

26. 发明授权

US07863438B2 Stable salt of 3′-phosphoadenosine 5′-phosphosulfate 有权
标题翻译： 3'-磷酸腺苷5'-磷酸硫酸盐的稳定盐
公开(公告)号：US07863438B2
公开(公告)日：2011-01-04
申请号：US12093743
申请日：2006-11-16
申请人： Kazuya Ishige , Takashi Kawakami , Toshitada Noguchi
发明人： Kazuya Ishige , Takashi Kawakami , Toshitada Noguchi
IPC分类号： C07H19/22
CPC分类号： C07H19/20
摘要： The present invention provides a stable salt of 3′-phosphoadenosine 5′-phosphosulfate (PAPS) and a production method therefor.The present invention is directed to a stable salt of PAPS (amine salt), which is formed between PAPS and an amine compound, and to a method for producing a stable salt of PAPS, which includes adding an amine compound to an aqueous PAPS solution in an amount by mole equal to or greater than that of PAPS, and lyophilizing the resultant solution.The present invention has first realized production of a solid-form PAPS salt having considerably improved stability through a very simple technique. Since the thus-produced amine salt of PAPS is very stable, the salt can be stored or employed without taking much care about decomposition thereof at ambient temperature.
摘要翻译：本发明提供稳定的3'-磷酸腺苷5'-磷酸硫酸盐（PAPS）及其制备方法。本发明涉及在PAPS和胺化合物之间形成的PAPS（胺盐）的稳定盐，以及PAPS稳定盐的制备方法，其包括向PAPS水溶液中加入胺化合物摩尔量等于或大于PAPS的量，并冻干所得溶液。本发明首先通过非常简单的技术实现了具有显着提高的稳定性的固体PAPS盐的生产。由于如此制得的PAPS胺盐非常稳定，所以可以在不在室温下分解的情况下储存或使用该盐。

27. 发明申请

US20100280424A1 MUSCLE FORCE ASSISTING DEVICE 审中-公开
标题翻译：肌肉力量辅助装置
公开(公告)号：US20100280424A1
公开(公告)日：2010-11-04
申请号：US12810611
申请日：2009-03-10
申请人： Takashi Kawakami , Toshihiko Ishiko , Keisuke Ueda
发明人： Takashi Kawakami , Toshihiko Ishiko , Keisuke Ueda
IPC分类号： A61H1/02
CPC分类号： B25J9/1075 , A61F5/0102 , A61F2002/5066 , A61H1/0237 , A61H1/0274 , A61H2201/165 , B25J9/0006
摘要： A muscle force assisting device includes a first attachment arranged along one bone of a joint, a second attachment arranged along the other bone of the joint, and a stretching-artificial muscle having one end provided on the first attachment and having the other end provided on the second attachment, in which an actuator that is extensible by supplying or discharging a substance such as gas, liquid and solid, or a mixture thereof is used as the stretching-artificial muscle, the muscle force assisting device assists motion of a user's joint such as an elbow, a knee and a wrist, a protecting member is provided on the first attachment as a path-restricting section that restricts a path of the stretching-artificial muscle, the protecting member restricts approach of the stretching-artificial muscle toward the joint, the stretching-artificial muscle is prevented from pressing a human body even if the path of the artificial muscle is changed by bending or stretching motion, and the a driving force of the artificial muscle can efficiently be converted into a stretching torque.
摘要翻译：肌肉力辅助装置包括沿着关节的一个骨头布置的第一附件，沿着关节的另一个骨头布置的第二附件和拉伸人造肌肉，其一端设置在第一附件上，并且另一端设置在使用第二附件，其中通过供应或排出诸如气体，液体和固体的物质或其混合物可延伸的致动器用作拉伸人造肌肉，肌力辅助装置辅助使用者的关节的运动，例如作为肘部，膝盖和手腕，在第一附件上设置有作为限制拉伸人造肌肉的路径的路径限制部的保护部件，保护部件限制拉伸人造肌肉朝向关节的接近即使通过弯曲或拉伸运动改变人造肌肉的路径，也可以防止拉伸人造肌肉压迫人体，人造肌肉的力可有效地转化为拉伸力矩。

28. 发明申请

US20100249948A1 WRIST ASSISTING APPARATUS 失效
标题翻译：手持辅助装置
公开(公告)号：US20100249948A1
公开(公告)日：2010-09-30
申请号：US12755651
申请日：2010-04-07
申请人： Takashi Kawakami , Toshihiko Ishiko , Keisuke Ueda
发明人： Takashi Kawakami , Toshihiko Ishiko , Keisuke Ueda
IPC分类号： A61F2/72 , A61F2/58
CPC分类号： A61F5/013 , A61F4/00
摘要： A wrist assisting apparatus can smoothly bend and stretch a joint even if a turning shaft of a joint and a rotation shaft of a wearing tool are deviated from each other. Also, an excessive load is not applied to a user. The wrist assisting apparatus of the present invention includes a palm support member for supporting a hand, angle changing members connected to sides of the palm support member, a front arm wearing tool disposed along the front arm, and joint members for forming a rotation shaft of the angle changing member with respect to the front arm wearing tool, wherein the angle changing members are provided on both sides of the palm support member, the joint members are provided on the angle changing members, respectively, and the joint members are located on both sides of a wrist.
摘要翻译：即使关节的转动轴和磨损工具的旋转轴彼此偏离，手腕辅助装置也能平滑地弯曲和拉伸关节。而且，不会对用户施加过大的负荷。本发明的手腕辅助装置包括用于支撑手的手掌支撑构件，连接到手掌支撑构件的侧面的角度改变构件，沿着前臂设置的前臂佩戴工具，以及用于形成旋转轴的旋转轴的接合构件所述角度改变构件相对于所述前臂佩戴工具，其中所述角度改变构件设置在所述手掌支撑构件的两侧，所述接合构件分别设置在所述角度改变构件上，并且所述接合构件位于两者上手腕的两侧。

29. 发明授权

US07590038B2 Storage medium initialization and cancellation method 失效
标题翻译：存储介质初始化和取消方法
公开(公告)号：US07590038B2
公开(公告)日：2009-09-15
申请号：US10403097
申请日：2003-04-01
申请人： Masato Hattori , Seiji Ohbi , Takashi Kawakami , Manabu Kii
发明人： Masato Hattori , Seiji Ohbi , Takashi Kawakami , Manabu Kii
IPC分类号： G11B7/00
CPC分类号： G11B20/1883 , G11B11/10523 , G11B11/10584 , G11B11/10595 , G11B20/00086 , G11B20/10 , G11B20/12 , G11B20/18 , G11B23/36 , G11B27/034 , G11B27/105 , G11B27/19 , G11B27/24 , G11B27/3027 , G11B27/32 , G11B27/329 , G11B27/34 , G11B27/36 , G11B2220/20 , G11B2220/2529
摘要： A storage medium initializing method includes steps of recording on a storage medium a management table configured to manage a replacement area for a defect area in a data area in the storage medium; recording a unique identification on the storage medium; and recording management data in the data area. The step of recording a unique identification includes recording the unique identification on the storage medium, but outside an area managed by the management data. The method optional includes initialization and cancellation steps.
摘要翻译：存储介质初始化方法包括以下步骤：在存储介质上记录被配置为管理存储介质中的数据区域中的缺陷区域的替换区域的管理表; 在存储介质上记录唯一的标识; 并在数据区中记录管理数据。记录唯一标识的步骤包括将唯一标识记录在存储介质上，但在由管理数据管理的区域之外。该方法可选包括初始化和取消步骤。

30. 发明申请

US20090118491A1 STABLE SALT OF 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE 有权
标题翻译：稳定的3'-磷酸腺苷5'-磷酸肌酸盐
公开(公告)号：US20090118491A1
公开(公告)日：2009-05-07
申请号：US12093743
申请日：2006-11-16
申请人： Kazuya Ishige , Takashi Kawakami , Toshitada Noguchi
发明人： Kazuya Ishige , Takashi Kawakami , Toshitada Noguchi
IPC分类号： C07H19/20
CPC分类号： C07H19/20
摘要： The present invention provides a stable salt of 3′-phosphoadenosine 5′-phosphosulfate (PAPS) and a production method therefor.The present invention is directed to a stable salt of PAPS (amine salt), which is formed between PAPS and an amine compound, and to a method for producing a stable salt of PAPS, which includes adding an amine compound to an aqueous PAPS solution in an amount by mole equal to or greater than that of PAPS, and lyophilizing the resultant solution.The present invention has first realized production of a solid-form PAPS salt having considerably improved stability through a very simple technique. Since the thus-produced amine salt of PAPS is very stable, the salt can be stored or employed without taking much care about decomposition thereof at ambient temperature.
摘要翻译：本发明提供稳定的3'-磷酸腺苷5'-磷酸硫酸盐（PAPS）及其制备方法。本发明涉及在PAPS和胺化合物之间形成的PAPS（胺盐）的稳定盐，以及PAPS稳定盐的制备方法，其包括向PAPS水溶液中加入胺化合物摩尔量等于或大于PAPS的量，并冻干所得溶液。本发明首先通过非常简单的技术实现了具有显着提高的稳定性的固体PAPS盐的生产。由于如此制得的PAPS胺盐非常稳定，所以盐可以在环境温度下储存或使用而不用担心其分解。

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