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21. 发明申请

US20090093526A1 INHIBITION OF P38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS 审中-公开
标题翻译：使用对称和非对称二苯醚类尿素抑制P38激酶
公开(公告)号：US20090093526A1
公开(公告)日：2009-04-09
申请号：US11932397
申请日：2007-10-31
申请人： Scott Miller , Martin Osterhout , Jacques Dumas , Uday Khire , Timothy B. Lowinger , William J. Scott , Roger A. Smith , Jill E. Wood , David E. Gunn , Holia Hatoum-Mokdad , Marell Rodriguez , Robert Sibley , Ming Wang , Tiffany Turner , Catherine Brennan
发明人： Scott Miller , Martin Osterhout , Jacques Dumas , Uday Khire , Timothy B. Lowinger , William J. Scott , Roger A. Smith , Jill E. Wood , David E. Gunn , Holia Hatoum-Mokdad , Marell Rodriguez , Robert Sibley , Ming Wang , Tiffany Turner , Catherine Brennan
IPC分类号： A61K31/40 , A61K31/44 , C07D207/36 , C07D213/04 , A61P19/02
CPC分类号： A61K31/17 , A61K31/341 , A61K31/381 , A61K31/4035 , A61K31/44 , A61K31/5375 , Y02A50/411
摘要： This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases and proteolytic enzyme mediated diseases, and pharmaceutical compositions for use in such therapy.
摘要翻译：本发明涉及一组芳基脲在治疗细胞因子介导的疾病和蛋白水解酶介导的疾病中的用途，以及用于这种治疗的药物组合物。

22. 发明授权

US07433323B2 Remote testing of high speed data and voice communication networks 有权
标题翻译：远程测试高速数据和语音通信网络
公开(公告)号：US07433323B2
公开(公告)日：2008-10-07
申请号：US10479431
申请日：2002-05-31
申请人： Roger A. Smith
发明人： Roger A. Smith
IPC分类号： H04L1/00 , H04L12/26
CPC分类号： H04M3/323 , H04L41/0659 , H04L41/0806 , H04L41/0856 , H04L43/50 , H04M3/2209 , H04M3/306
摘要： Faults or degradation of performance of a voice/data communication network (2) are identified without the need to dispatch service personnel by selectively testing isolated sections of the communication network. For some of these tests, the communication network address of a customer's modem under test (106, 114, 60, 66) is retrieved from a database (88) for use in directing these tests to the customer's modem (106, 114, 60, 66) and for emulating the customer's modem (106, 114, 60, 66) during one or more of the tests.
摘要翻译：识别语音/数据通信网络（2）的故障或性能下降，而不需要通过选择性地测试通信网络的隔离部分来派遣服务人员。对于这些测试中的一些，从数据库（88）检索被测客户调制解调器（106,114,60,66）的通信网络地址，以用于将这些测试引导到客户的调制解调器（106,114,60,66） 66）和用于在一个或多个测试期间模拟客户的调制解调器（106,114,60,66）。

23. 发明授权

US06699860B2 Di-substituted aminomethyl-chroman derivative beta-3 adrenoreceptor agonists 失效
标题翻译：二取代氨基甲基 - 苯并二氢吡喃衍生物β-3肾上腺素受体激动剂
公开(公告)号：US06699860B2
公开(公告)日：2004-03-02
申请号：US10008928
申请日：2001-12-07
申请人： Gaetan H. Ladouceur , William H. Bullock , Steven R. Magnuson , Stephen J. O'Connor , Roger A. Smith , Quanrong Shen , Qingjie Liu , Ning Su , Emil J. Velthuisen , Ann-Marie Campbell , Paul P. Ehrlich
发明人： Gaetan H. Ladouceur , William H. Bullock , Steven R. Magnuson , Stephen J. O'Connor , Roger A. Smith , Quanrong Shen , Qingjie Liu , Ning Su , Emil J. Velthuisen , Ann-Marie Campbell , Paul P. Ehrlich
IPC分类号： C07D40112
CPC分类号： C07D405/12 , C07D311/58 , C07D407/04 , C07D409/04 , C07D417/04
摘要： This invention is related to novel di-substituted aminomethyl chroman derivatives which are useful in the treatment of beta-3 receptor-mediated conditions.
摘要翻译：本发明涉及可用于治疗β-3受体介导的病症的新型二取代氨基甲基苯并二氢吡喃衍生物。

24. 发明授权

US6062930A Multipurpose recreational mat 失效
标题翻译：多用途娱乐垫
公开(公告)号：US6062930A
公开(公告)日：2000-05-16
申请号：US176307
申请日：1998-10-22
申请人： Roger A. Smith
发明人： Roger A. Smith
IPC分类号： A47C15/00 , B63B7/02 , B63B35/74 , B63C9/08
CPC分类号： A47C15/006 , B63B35/74 , B63B7/02
摘要： A multipurpose recreational mat for primary use in water and a secondary use on an inflexible surface. The mat comprises three flotation bodies preferably made of a closed cell polyurethane foam. A waterproof unitary cover surrounds the flotation bodies formed by a specific process. A strap is provided for use in carrying or storage and while an individual is sitting on the mat while floating in the water. At least one grommet in each flotation body cover permits drainage of any water entering through the stitched seams.
摘要翻译：用于水中主要使用的多用途休闲垫，在不灵活表面上的二次使用。该垫包括优选由闭孔聚氨酯泡沫制成的三个浮选体。防水整体罩围绕由特定工艺形成的浮选体。提供用于携带或存放的带子，而个人在漂浮在水中时坐在垫子上。每个浮选机体盖中至少有一个垫圈允许通过缝合接缝进入的任何水的排水。

25. 发明授权

US5648924A Method and apparatus for finding arctangents 失效
标题翻译：发现反正切的方法和装置
公开(公告)号：US5648924A
公开(公告)日：1997-07-15
申请号：US424033
申请日：1995-04-18
申请人： Roger A. Smith
发明人： Roger A. Smith
IPC分类号： G06F7/548
CPC分类号： G06F7/548
摘要： Arctangents (tan.sup.-1) are calculated utilizing binary floating point numbers through much of the function's range by extracting into an Integer Register (54) as an index ("i") the exponent and a specified number of fraction bits from a Floating Point Register(s) (60). The index is utilized by an Integer Unit (52) to index into tables of polynomial coefficients and reference values. The floating point difference between the absolute value of the argument(s) and the reference value selected by the index is a polynomial linear term. The coefficients in the table entry selected by the index are multiplied in a Floating Point Unit (58) by integral powers of the linear term. The Floating Point Unit (58) then sums the high order polynomial terms. The zero.sup.th level term added to the product of the first level term multiplied by the linear term forms a "big" term. The rounding error resulting from the computation of the "Big" Term is calculated as a "Small" Term, which is added to the high order polynomial terms before the Big Term is added.
摘要翻译：通过将整数寄存器（54）提取为指数（“i”）和浮点寄存器的指定数量的分数比特，通过大部分功能范围的二进制浮点数来计算Arctangents（tan-1）（s）（60）。索引由整数单元（52）用于索引到多项式系数和参考值的表中。参数的绝对值与由索引选择的参考值之间的浮点差是多项式线性项。由索引选择的表条目中的系数在浮点单元（58）中乘以线性项的积分功率。浮点单元（58）然后对高阶多项式项求和。添加到第一级项的乘积中的第零级项被乘以线性项形成“大”项。计算“大”项时产生的舍入误差被计算为“小”项，它被添加到加入大期限之前的高阶多项式项。

26. 发明授权

US5570310A Method and data processor for finding a logarithm of a number 失效
标题翻译：用于查找数字对数的方法和数据处理器
公开(公告)号：US5570310A
公开(公告)日：1996-10-29
申请号：US349571
申请日：1994-12-05
申请人： Roger A. Smith
发明人： Roger A. Smith
IPC分类号： G06F7/556 , G06F1/02
CPC分类号： G06F7/556
摘要： A data processor and method are used to find log.sub.p (x) wherein p is a numerical base and x is a floating point value. The method begins by deriving a number y from the quantity x wherein the number y has a predetermined sign portion, a predetermined exponent portion, and the fraction portion f. The predetermined fraction portion f being a truncated portion of x. A logarithm to the predetermined base p of the number y is found by calculating:log.sub.p (y)=-log.sub.p (a)+log.sub.p (1+(ay-1))where the constant a is read from a memory table of constants indexed by an index i. Index i is calculated from y where the fraction portion f of y lies in the range of 1.ltoreq.y
摘要翻译：使用数据处理器和方法来查找logp（x），其中p是数字库，x是浮点值。该方法通过从数量x导出数量y开始，其中数量y具有预定符号部分，预定指数部分和分数部分f。预定分数部分f是x的截断部分。通过计算：logp（y）= - logp（a）+ logp（1+（ay-1））找出数目y的预定基数p的对数，其中常数a是从索引的常数的存储表中读取的通过索引我索引i由y计算，其中y的分数部分f位于1

27. 发明授权

US5546333A Data processor having a data table for performing a dual function of alphanumeric notice and numerical calculations 失效
标题翻译：数据处理器具有用于执行字母数字通知和数值计算的双重功能的数据表
公开(公告)号：US5546333A
公开(公告)日：1996-08-13
申请号：US546260
申请日：1995-10-20
申请人： Roger A. Smith
发明人： Roger A. Smith
IPC分类号： G06F7/556 , G06F12/14 , H04L9/00
CPC分类号： G06F7/556
摘要： A data processor and method are used to find log.sub.p (x) wherein p is a numerical base and x is a floating point value. The method begins by deriving a number y from the quantity x wherein the number y has a predetermined sign portion, a predetermined exponent portion, and the fraction portion f, the predetermined fraction portion f being a truncated portion of x. A logarithm to the predetermined base p of the number y is found by calculating:log.sub.p (y)=-log.sub.p (a)+log.sub.p (1+(ay-1))where the constant a is read from a memory table of constants indexed by an index i. Index i is calculated from y where the fraction portion f of y lies in the range of 1.ltoreq.y
摘要翻译：使用数据处理器和方法来查找logp（x），其中p是数字库，x是浮点值。该方法通过从数量x导出数量y开始，其中数量y具有预定符号部分，预定指数部分和分数部分f，预定分数部分f是x的截断部分。通过计算：logp（y）= - logp（a）+ logp（1+（ay-1））找出数量y的预定基数p的对数，其中常数a是从索引的常数的存储表中读取的通过索引我索引i由y计算，其中y的分数部分f位于1

28. 发明授权

US5055451A Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors 失效
标题翻译： ARYLOXY和ARYLACYLOXY METHYL KETONES作为THIOL蛋白酶抑制剂
公开(公告)号：US5055451A
公开(公告)日：1991-10-08
申请号：US127282
申请日：1987-12-07
申请人： Alexander Krantz , Heinz W. Pauls , Roger A. Smith , Robin W. Spencer
发明人： Alexander Krantz , Heinz W. Pauls , Roger A. Smith , Robin W. Spencer
IPC分类号： C12N9/99 , A61K31/135 , A61K31/165 , A61K31/235 , A61K38/00 , A61K38/55 , A61P3/00 , A61P9/08 , A61P9/10 , A61P15/00 , A61P29/00 , A61P43/00 , C07C67/00 , C07C231/00 , C07C231/02 , C07C233/31 , C07C233/76 , C07C235/08 , C07C237/08 , C07C237/20 , C07C237/22 , C07C239/00 , C07C271/22 , C07C271/54 , C07C279/14 , C07C311/19 , C07C313/00 , C07C323/59 , C07K1/113 , C07K5/06 , C07K5/065 , C07K5/078 , C07K5/087 , C07K14/81
CPC分类号： C07K5/0812 , C07C271/22 , C07K5/06078 , C07K5/06165 , C07K5/06191 , A61K38/00 , Y02P20/55
摘要： Thiol protease inhibitors are disclosed having the formula: ##STR1## or an optical isomer thereof, or a pharmaceutically acceptable salt thereof, wherein:n is 0 or 1;m is 0, 1 or 2;X is H or an N-protecting group;each Y is independently an optionally protected .alpha.-amino acid residue;R is an optionally protected .alpha.-amino acid side chain that is H or CH.sub.3 or that is bonded to the .alpha.-carbon atom to which it is attached by a methylene, methine or phenyl radical; andR' is optionally substituted aryl.

29. 发明申请

US20130054162A1 METHODS AND APPARATUS FOR DETERMINING CONDITIONS OF POWER LINES 审中-公开
标题翻译：用于确定电力线条件的方法和装置
公开(公告)号：US20130054162A1
公开(公告)日：2013-02-28
申请号：US13546577
申请日：2012-07-11
申请人： Roger A. Smith , Rebecca Ross
发明人： Roger A. Smith , Rebecca Ross
IPC分类号： G01R31/08
CPC分类号： H02J3/00 , G01R15/142 , H02J13/00 , H02J2003/001 , H02J2003/007 , Y02E60/74 , Y02E60/76 , Y04S10/30 , Y04S10/525 , Y04S40/22
摘要： Techniques for determining conditions of power lines in a power distribution system based on data collected by a plurality of sensor units deployed in the power distribution system. The techniques include obtaining data associated with measurements collected by at least two sensor units in the plurality of sensor units, and determining, by using at least one processor, at least one condition of at least one power line in the power distribution system by using the data obtained by the at least two sensor units.
摘要翻译：基于部署在配电系统中的多个传感器单元收集的数据来确定配电系统中的电力线路状况的技术。这些技术包括获得与由多个传感器单元中的至少两个传感器单元收集的测量相关联的数据，以及通过使用至少一个处理器来确定配电系统中的至少一个电力线的至少一个状态，由至少两个传感器单元获得的数据。

30. 发明申请

US20120142742A1 OMEGA-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS 有权
标题翻译：作为RAF激酶抑制剂的OMEGA-CARBOXYARYL替代二苯醚
公开(公告)号：US20120142742A1
公开(公告)日：2012-06-07
申请号：US13368812
申请日：2012-02-08
申请人： Bernd Riedl , Jacques Dumas , Uday Khire , Timothy B. Lowinger , William J. Scott , Roger A. Smith , Jill E. Wood
发明人： Bernd Riedl , Jacques Dumas , Uday Khire , Timothy B. Lowinger , William J. Scott , Roger A. Smith , Jill E. Wood
IPC分类号： A61K31/44 , A61P35/00
CPC分类号： C07C275/36 , C07C275/28 , C07C275/30 , C07C275/32 , C07C275/40 , C07C311/29 , C07C317/22 , C07D209/46 , C07D209/48 , C07D213/75 , C07D213/81 , C07D213/82 , C07D295/13 , C07D295/135 , C07D295/192 , C07D413/12
摘要： This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
摘要翻译：本发明涉及一组芳基脲在治疗raf介导的疾病中的用途，以及用于此类治疗的药物组合物。

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