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21. 发明授权

US08100979B2 Method and system for mammalian joint resurfacing 有权
标题翻译：哺乳动物关节表面置换的方法和系统
公开(公告)号：US08100979B2
公开(公告)日：2012-01-24
申请号：US12479402
申请日：2009-06-05
申请人： Jeffrey C Felt , Mark A. Rydell , Paul J. Buscemi , Alexander Arsenyev , Christopher H. Porter
发明人： Jeffrey C Felt , Mark A. Rydell , Paul J. Buscemi , Alexander Arsenyev , Christopher H. Porter
IPC分类号： A61F2/44
CPC分类号： A61B17/562 , A61F2/30721 , A61F2/34 , A61F2/38 , A61F2/3872 , A61F2/3877 , A61F2/389 , A61F2002/30535 , A61F2250/0058 , A61L27/18 , A61L2430/24 , C08G18/10 , C08G18/4854 , C08G18/61 , C08G18/69 , C08L75/04 , C08G18/32
摘要： A method and system for the creation or modification of the wear surface of orthopedic joints, involving the preparation and use of one or more partially or fully preformed and procured components, adapted for insertion and placement into the body and at the joint site. In a preferred embodiment, component(s) can be partially cured and generally formed ex vivo and further and further formed in vivo at the joint site to enhance conformance and improve long term performance. In another embodiment, a preformed balloon or composite material can be inserted into the joint site and filled with a flowable biomaterial in situ to conform to the joint site. In yet another embodiment, the preformed component(s) can be fully cured and formed ex vivo and optionally further fitted and secured at the joint site. Preformed components can be sufficiently pliant to permit insertion through a minimally invasive portal, yet resilient enough to substantially assume, or tend towards, the desired form in vivo with additional forming there as needed.
摘要翻译：一种用于创建或修改整形外科关节磨损表面的方法和系统，涉及准备和使用一种或多种部分或完全预成型和采购的部件，适于插入和放置在身体和关节部位。在一个优选的实施方案中，组分可以部分固化，并且通常在体外形式离体进一步形成并且在接合部位进一步形成，以增强一致性并改善长期性能。在另一个实施方案中，预先形成的球囊或复合材料可以插入到关节部位中并且在原位填充可流动的生物材料以符合关节部位。在另一个实施方案中，预成型组分可以完全固化并离体形成，并任选地进一步装配并固定在接头部位。预成型组件可以足够柔顺以允许通过微创入口插入，但足够弹性足以基本上假设或倾向于体内所需的形式，并根据需要进一步形成。

22. 发明授权

US08052662B2 Skin abrasion system and method 有权
标题翻译：皮肤磨损系统和方法
公开(公告)号：US08052662B2
公开(公告)日：2011-11-08
申请号：US12098844
申请日：2008-04-07
申请人： Brian D. Zelickson , David A. Kist , Mark A. Rydell
发明人： Brian D. Zelickson , David A. Kist , Mark A. Rydell
IPC分类号： A61M35/00 , A46B13/00
CPC分类号： A45D26/0004 , A45D44/00 , A61B17/54 , A61B2017/00128 , A61B2017/00132 , A61B2017/00199 , A61B2017/00464 , A61B2017/00473 , A61B2017/00477 , A61B2017/00734 , A61B2017/00761 , A61B2017/320008 , A61B2017/320076 , A61B2017/320078 , A61B2090/065 , A61K8/0208 , A61Q9/04
摘要： A system and method for rejuvenating skin through ablation using a handheld device (200) having a removable treatment component (213) with an abrasive material on one surface of the component which surface is on a portion of the treatment component (213) configured to conform to a skin surface. The system further includes application of other elements to facilitate skin recovery and rejuvenation processes.
摘要翻译：一种用于通过消融来恢复皮肤的系统和方法，所述手持式装置（200）具有可移除处理部件（213），所述手术装置在所述部件的一个表面上具有研磨材料，该表面位于所述处理部件（213）的被配置为符合到皮肤表面。该系统还包括应用其他元素以促进皮肤恢复和复原过程。

23. 发明申请

US20090276047A1 RAIL-BASED MODULAR DISC PROSTHESIS 审中-公开
标题翻译：基于轨道的模块化DISC PROSTHISISIS
公开(公告)号：US20090276047A1
公开(公告)日：2009-11-05
申请号：US12435087
申请日：2009-05-04
申请人： Jeffrey C. Felt , Mark A. Rydell , Stephen H. Crosbie
发明人： Jeffrey C. Felt , Mark A. Rydell , Stephen H. Crosbie
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/30014 , A61F2002/30016 , A61F2002/30075 , A61F2002/30166 , A61F2002/30235 , A61F2002/30383 , A61F2002/30387 , A61F2002/30462 , A61F2002/3052 , A61F2002/30561 , A61F2002/30563 , A61F2002/30594 , A61F2002/30604 , A61F2002/30677 , A61F2002/30971 , A61F2002/444 , A61F2002/4627 , A61F2210/0061 , A61F2220/0025 , A61F2220/0075 , A61F2230/0028 , A61F2230/0069 , A61F2250/0018 , A61F2250/0019
摘要： A method and apparatus for repairing a damaged intervertebral disc nucleus in a minimally invasive manner utilizes a modular disc prosthesis preferably comprised of at least three modular segments and at least two rails that operably connect adjacent modular segments. In one embodiment, each modular segment includes a harder inner portion and a softer outer portion. Preferably, the rails operate to slidably connect and interlock adjacent modular segments. A stem portion of the rails that extends outside the periphery of the body of the prosthesis is removable after implantation such that the modular segments form an implanted unitary device that closely mimics the geometry of the disc nucleus cavity.
摘要翻译：用于以微创方式修复损伤的椎间盘细胞核的方法和装置利用模块化椎间盘假体，优选地包括至少三个模块化区段和至少两个可操作地连接相邻模块区段的轨道。在一个实施例中，每个模块化区段包括较硬的内部部分和较软的外部部分。优选地，轨道操作以可滑动地连接和互锁相邻的模块段。在植入之后延伸到假体本体周边之外的轨道的茎部分是可去除的，使得模块化部分形成与模腔细胞核的几何形状紧密相似的植入的整体装置。

24. 发明授权

US07591853B2 Rail-based modular disc nucleus prosthesis 有权
标题翻译：基于轨道的模块椎间盘假体
公开(公告)号：US07591853B2
公开(公告)日：2009-09-22
申请号：US11372477
申请日：2006-03-09
申请人： Jeffrey C. Felt , Mark A. Rydell , Stephen H. Crosbie , John E. Sherman
发明人： Jeffrey C. Felt , Mark A. Rydell , Stephen H. Crosbie , John E. Sherman
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/30014 , A61F2002/30016 , A61F2002/30075 , A61F2002/30166 , A61F2002/30235 , A61F2002/30383 , A61F2002/30387 , A61F2002/30462 , A61F2002/3052 , A61F2002/30561 , A61F2002/30563 , A61F2002/30594 , A61F2002/30604 , A61F2002/30677 , A61F2002/30971 , A61F2002/444 , A61F2002/4627 , A61F2210/0061 , A61F2220/0025 , A61F2220/0075 , A61F2230/0028 , A61F2230/0069 , A61F2250/0018 , A61F2250/0019
摘要： A method and apparatus for repairing a damaged intervertebral disc nucleus in a minimally invasive manner utilizes a modular disc prosthesis preferably comprised of at least three modular segments and at least two rails that operably connect adjacent modular segments. In one embodiment, each modular segment includes a harder inner portion and a softer outer portion. Preferably, the rails operate to slidably connect and interlock adjacent modular segments. A stem portion of the rails that extends outside the periphery of the body of the prosthesis is removable after implantation such that the modular segments form an implanted unitary device that closely mimics the geometry of the disc nucleus cavity.
摘要翻译：用于以微创方式修复损伤的椎间盘细胞核的方法和装置利用模块化椎间盘假体，优选地包括至少三个模块化区段和至少两个可操作地连接相邻模块区段的轨道。在一个实施例中，每个模块化区段包括较硬的内部部分和较软的外部部分。优选地，轨道操作以可滑动地连接和互锁相邻的模块段。在植入之后延伸到假体本体周边之外的轨道的茎部分是可去除的，使得模块化部分形成与模腔细胞核的几何形状紧密相似的植入的整体装置。

25. 发明授权

US06110101A Bladder sling 失效
标题翻译：膀胱吊带
公开(公告)号：US06110101A
公开(公告)日：2000-08-29
申请号：US274619
申请日：1999-03-23
申请人： Claude Tihon , Mark A. Rydell , William P. Ryan
发明人： Claude Tihon , Mark A. Rydell , William P. Ryan
IPC分类号： A61B17/00 , A61B17/02 , A61B17/06 , A61F2/00 , A61F2/02 , A61F5/48
CPC分类号： A61B17/0218 , A61F2/0045 , A61B2017/00805 , A61B2017/0225 , A61B2017/0618
摘要： A sling for supporting the urethra and neck of the bladder to prevent urinary incontinence is disclosed. The sling is designed to provide sufficient support to inhibit the unintended flow of urine, yet stretch in a controlled fashion so that the bladder can be voided at approximate times.
摘要翻译：公开了用于支撑膀胱的尿道和颈部以防止尿失禁的吊带。吊索被设计成提供足够的支撑以抑制尿液的意外流动，但以受控的方式拉伸，使得膀胱在近似时间可以被排除。

26. 发明授权

US5931774A Inflatable devices for tumor treatment 失效
标题翻译：用于肿瘤治疗的充气装置
公开(公告)号：US5931774A
公开(公告)日：1999-08-03
申请号：US727259
申请日：1996-10-07
申请人： Jeffery A. Williams , Christopher H. Porter , Mark A. Rydell
发明人： Jeffery A. Williams , Christopher H. Porter , Mark A. Rydell
IPC分类号： A61F2/82 , A61B17/00 , A61M1/00 , A61M5/42 , A61M25/10 , A61M27/00 , A61M36/00 , A61M36/06 , A61M39/02 , A61N1/40 , A61N5/10 , A61N7/02 , A61N5/02
CPC分类号： A61N5/1015 , A61M25/1011 , A61M39/0208 , A61N1/40 , A61N1/403 , A61N5/1001 , A61N5/1007 , A61N7/02 , A61B2017/00084 , A61M2025/1013 , A61M2039/0211 , A61M2205/051 , A61M2205/32 , A61M2210/0687 , A61M2210/0693 , A61M27/006 , A61M39/0247 , A61M5/427 , A61N2005/1021 , A61N5/1002 , A61N5/1014
摘要： Implantable devices for treatment of proliferative disorders are described. In one aspect, the invention provides an implantable apparatus for treating a proliferative disorder in a patient. The device comprises a treatment fluid receptacle for receiving a treatment fluid, an inflatable balloon having a balloon body, a catheter connected between the treatment fluid receptacle and the balloon and defining a fluid flow path therebetween, and a diffusion barrier disposed in the fluid flow path between the treatment fluid receptacle and the balloon. Methods for treating proliferative disorders with the devices are also disclosed.
摘要翻译：描述了用于治疗增殖性疾病的可植入装置。一方面，本发明提供了一种用于治疗患者的增殖性病症的可植入装置。该装置包括用于接收处理流体的处理流体容器，具有球囊体的可膨胀气囊，连接在处理流体容器和球囊之间并且限定其间的流体流动路径的导管以及设置在流体流路中的扩散阻挡层处理液容器和气囊之间。还公开了用该装置治疗增殖性疾病的方法。

27. 发明授权

US5282799A Bipolar electrosurgical scalpel with paired loop electrodes 失效
标题翻译：双极电外科手术刀配对环形电极
公开(公告)号：US5282799A
公开(公告)日：1994-02-01
申请号：US728337
申请日：1991-07-11
申请人： Mark A. Rydell
发明人： Mark A. Rydell
IPC分类号： A61B16/00 , A61B18/00 , A61B18/14 , A61M1/00 , A61M3/02 , A61B17/39
CPC分类号： A61B18/1402 , A61B2018/00607 , A61B2018/0097 , A61B2018/126 , A61B2018/1407 , A61M3/0279
摘要： A bipolar electrosurgical scalpel comprising a handle having a pair of loop electrodes extending outwardly from the distal end thereof in parallel, spaced relation, such that the spacing defines a dielectric such as an air gap therebetween. When a RF voltage of a predetermined amplitude is applied across the two electrodes and they are drawn across tissue, cutting occurs by virtue of the arc established between the two electrodes. The electrodes may be formed from tungsten wire to withstand high operating temperatures and are sufficiently rigid to withstand the pressure forces encountered during electrosurgery without shorting together across the gap. The electrodes may be formed in various shapes, depending upon the nature of the cutting desired. Possible configurations include open rounded loops, open elongated loops, open triangular-shaped loops, L- or J-shaped hooks. The supporting conductors to which these electrodes are affixed may be straight tubular legs or curved hooks formed from flattened lengths of metal tubing. The loop electrodes may also be ultrasonically vibrated and/or fluid flushed to enhance removal of char and tissue debris during use. To enhance coagulation properties, metal surface electrodes of relatively large area may be embedded in an insulating end cap of the scalpel and the loop cutting electrodes are designed to be retracted therein such that only the surface electrodes are exposed. The instrument is controlled by either a hand switch or a standard surgical foot switch.
摘要翻译：一种双极电外科手术刀，其包括具有一对环形电极的手柄，所述一对环形电极从其远端向外平行地间隔开地向外延伸，使得所述间隔限定电介质，例如它们之间的气隙。当在两个电极之间施加预定幅度的RF电压并且它们被拉过组织时，由于在两个电极之间建立的电弧而进行切割。电极可以由钨丝形成以承受高的操作温度，并且具有足够的刚性以承受在电外科手术期间遇到的压力，而不会跨越间隙一起短路。取决于所需切割的性质，电极可以形成各种形状。可能的配置包括开放的圆形环，开放的细长环，开放的三角形环，L形或J形钩。固定这些电极的支撑导体可以是由扁平的一段金属管形成的直管状腿或弯曲钩。循环电极也可以被超声振动和/或流体冲洗以增强使用期间焦炭和组织碎屑的去除。为了增强凝固性能，相对大面积的金属表面电极可以嵌入在解剖刀的绝缘端盖中，并且环形切割电极被设计成在其中缩回，使得仅表面电极暴露。仪器由手动开关或标准手术脚踏开关控制。

28. 发明授权

US5250047A Bipolar laparoscopic instrument with replaceable electrode tip assembly 失效
标题翻译：具有可更换电极头组件的双极腹腔镜仪器
公开(公告)号：US5250047A
公开(公告)日：1993-10-05
申请号：US780045
申请日：1991-10-21
申请人： Mark A. Rydell
发明人： Mark A. Rydell
IPC分类号： A61B1/00 , A61B17/32 , A61B18/00 , A61B18/14 , A61B17/39
CPC分类号： A61B18/1482 , A61B18/1402
摘要： An electrosurgical instrument for use in endoscopic procedures features an electrode assembly which can be readily connected and disconnected from the remaining body of the instrument to allow a replacement electrode assembly to be substituted. The instrument comprises an elongated rigid tube having a handle on the proximal end, the handle including a spring-loaded plunger which is connected by a push rod to a stem member disposed in the lumen of the tube near its distal end. The electrode assembly is designed to mate with the stem and when the plunger is actuated to extend the stem beyond the distal end of the tube, the electrode assembly may be installed. Retraction of the stem within the lumen of the tube serves to hold the electrode assembly in place.

29. 发明授权

US5085659A Biopsy device with bipolar coagulation capability 失效
标题翻译：具有双极凝血能力的活检装置
公开(公告)号：US5085659A
公开(公告)日：1992-02-04
申请号：US616562
申请日：1990-11-21
申请人： Mark A. Rydell
发明人： Mark A. Rydell
IPC分类号： A61B1/00 , A61B10/00 , A61B10/02 , A61B10/04 , A61B10/06 , A61B17/00 , A61B17/22 , A61B18/00 , A61B18/04 , A61B18/14 , G01N1/04
CPC分类号： A61B10/04 , A61B17/32075 , A61B18/1492 , A61B10/02 , A61B18/1402 , A61B2017/00292 , A61B2018/00196
摘要： A biopsy instrument comprises an elongated flexible tube having a sharpened metal sleeve affixed to its distal end. An anvil member is affixed to the distal end of an elongated rod or wire which fits through the lumen of the tube and which is reciprocally moveable in the longitudinal direction by appropriately manipulating a handle device affixed to the proximal end of the tube. Affixed to the anvil member and electrically connected to the rod is an electrode. Means are provided for connecting an RF voltage between the electrode and metal sleeve for coagulating blood at the site where a tissue sample is excised from the internal wall of a body organ. The tissue sample is excised by positioning it against the sharpened edge of the metal sleeve and drawing back on the anvil to sever the sample and draw it into the interior of the sleeve where it remains until removed.

30. 发明授权

US5047026A Electrosurgical implement for tunneling through tissue 失效
标题翻译：用于穿透组织的电外科手术器械
公开(公告)号：US5047026A
公开(公告)日：1991-09-10
申请号：US546871
申请日：1990-07-02
申请人： Mark A. Rydell
发明人： Mark A. Rydell
IPC分类号： A61B17/00 , A61B18/14
CPC分类号： A61B18/1482 , A61B18/1402 , A61B2017/00292 , A61B2018/00107
摘要： An electrosurgical implement for tunneling through tissue for effecting drainage of an organ or to restore patency to a blood vessel is described. The implement comprises a stainless steel, helically wound, wire body similar to a conventional guidewire of the type used in angiography, angioplasty or in implanting cardiac pacing leads. The exterior of the guidewire is coated with an insulating material, save for one or two convolutions at its distal end. A core wire having a Teflon.RTM. shrink tube surrounding it over substantially its entire length is disposed within the lumen of the helical guidewire and only a short segment of the distal end of the core wire is allowed to extend out from the distal end of the guidewire. This short segment is stripped free of insulation. The implement may be routed through an endoscope into the stomach or colon and when an RF voltage of an appropriate amplitude is connected across terminals electrically joined to the proximal ends of both of the guidewire and the core wire, an arc discharge is created when the distal end of the implement is brought into contact with tissue, thereby allowing the device to readily pierce this tissue. The same implement may also be used for restoring patency to a blocked blood vessel.
摘要翻译：描述了用于隧道穿过组织以实现器官排水或恢复对血管通畅的电外科器具。该器具包括不锈钢，螺旋缠绕的线体，其类似于用于血管造影，血管成形术或植入心脏起搏引线的类型的常规导丝。导线的外部涂有绝缘材料，在其远端除了一个或两个卷取。具有围绕其整个长度的Teflon TM收缩管的芯线设置在螺旋导丝的内腔内，并且仅允许芯线的远端的短段从导丝的远端延伸出。这个短段被剥去没有绝缘。器具可以通过内窥镜路线进入胃或结肠，当电连接到导线和芯线的近端的端子上连接适当振幅的RF电压时，当远端使器具的端部与组织接触，从而允许器件容易地刺穿该组织。相同的器具也可用于恢复到阻塞血管的通畅。

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