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1. 发明授权

US09005173B2 Skin abrasion system and method 有权
标题翻译：皮肤磨损系统和方法
公开(公告)号：US09005173B2
公开(公告)日：2015-04-14
申请号：US13241734
申请日：2011-09-23
申请人： Brian D. Zelickson , David A. Kist , Mark A. Rydell
发明人： Brian D. Zelickson , David A. Kist , Mark A. Rydell
IPC分类号： A61M35/00 , A61B17/50 , A61H1/00 , A61H7/00 , A45D26/00 , A45D44/00 , A61B17/54 , A61K8/02 , A61Q9/04 , A61B17/00 , A61B17/32 , A61B19/00
CPC分类号： A45D26/0004 , A45D44/00 , A61B17/54 , A61B2017/00128 , A61B2017/00132 , A61B2017/00199 , A61B2017/00464 , A61B2017/00473 , A61B2017/00477 , A61B2017/00734 , A61B2017/00761 , A61B2017/320008 , A61B2017/320076 , A61B2017/320078 , A61B2090/065 , A61K8/0208 , A61Q9/04
摘要： A system and method for rejuvenating skin through ablation using a handheld device (200) having a removable treatment component (213) with an abrasive material on one surface of the component which surface is on a portion of the treatment component (213) configured to conform to a skin surface. The system further includes application of other elements to facilitate skin recovery and rejuvenation processes.
摘要翻译：一种用于通过消融来恢复皮肤的系统和方法，所述手持式装置（200）具有可移除处理部件（213），所述手术装置在所述部件的一个表面上具有研磨材料，该表面位于所述处理部件（213）的被配置为符合到皮肤表面。该系统还包括应用其他元素以促进皮肤恢复和复原过程。

2. 发明申请

US20100106102A1 APPARATUS FOR DELIVERY OF DEVICE AND ANTIMICROBIAL AGENT INTO TRANS-DERMAL CATHETER 有权
标题翻译：用于将装置和抗微生物剂递送到透明导管的装置
公开(公告)号：US20100106102A1
公开(公告)日：2010-04-29
申请号：US12605963
申请日：2009-10-26
申请人： Robert J. Ziebol , William S. Nettekoven , Mark A. Rydell
发明人： Robert J. Ziebol , William S. Nettekoven , Mark A. Rydell
IPC分类号： A61L29/14
CPC分类号： A61M25/01 , A61L2/186 , A61L2202/24 , A61M5/001 , A61M25/0017 , A61M25/0105 , A61M25/0111 , A61M39/165 , A61M39/18 , A61M39/20 , A61M2025/0018 , A61M2025/0019 , A61M2025/0056 , A61M2209/10
摘要： An apparatus for delivery of an elongate member into the lumen of a trans-dermal catheter. In a preferred embodiment, the apparatus comprises a protective sheath configured to at least substantially surround an elongate member; and slidable member configured to travel along the protective sheath, the slidable member operatively coupled to the elongate member; wherein the elongate member is insertable into a lumen of a trans-dermal catheter by moving the slidable member along at least a part of the length of the protective sheath. In another embodiment, the apparatus comprises a protective sheath configured to at least substantially surround an elongate member; a slidable member configured to travel along the protective sheath, the slidable member operatively coupled to the elongate member; and a connecting member positioned on the distal end of the protective sheath, the connecting member configured to lock onto the distal end of a trans-dermal catheter; wherein the elongate member is insertable into the lumen of the trans-dermal catheter by moving the slidable member along at least a part of the length of the protective sheath.
摘要翻译：用于将细长构件递送到经皮导管的内腔中的装置。在优选实施例中，该装置包括被配置为至少基本上围绕细长构件的保护护套; 以及可滑动构件，其构造成沿着所述保护护套行进，所述可滑动构件可操作地联接到所述细长构件; 其中所述细长构件通过沿着所述保护护套的长度的至少一部分移动所述可滑动构件而可插入到经皮导管的内腔中。在另一个实施例中，该装置包括被配置为至少基本上围绕细长构件的保护套; 可滑动构件，其构造成沿着所述保护护套行进，所述可滑动构件可操作地联接到所述细长构件; 以及连接构件，所述连接构件定位在所述保护护套的远端上，所述连接构件构造成锁定在经皮导管的远端上; 其中所述细长构件通过沿着所述保护护套的长度的至少一部分移动所述可滑动构件而可插入所述经皮导管的内腔中。

3. 发明申请

US20100057144A1 RAIL-BASED MODULAR DISC NUCLEUS PROSTHESIS 审中-公开
标题翻译：基于轨道的模块化核心预测
公开(公告)号：US20100057144A1
公开(公告)日：2010-03-04
申请号：US12548225
申请日：2009-08-26
申请人： Jeffrey C. Felt , Mark A. Rydell , Stephen H. Crosbie , John E. Sherman
发明人： Jeffrey C. Felt , Mark A. Rydell , Stephen H. Crosbie , John E. Sherman
IPC分类号： A61B17/56
CPC分类号： A61F2/442 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/30014 , A61F2002/30016 , A61F2002/30075 , A61F2002/30166 , A61F2002/30235 , A61F2002/30383 , A61F2002/30387 , A61F2002/30462 , A61F2002/3052 , A61F2002/30561 , A61F2002/30563 , A61F2002/30594 , A61F2002/30604 , A61F2002/30677 , A61F2002/30971 , A61F2002/444 , A61F2002/4627 , A61F2210/0061 , A61F2220/0025 , A61F2220/0075 , A61F2230/0028 , A61F2230/0069 , A61F2250/0018 , A61F2250/0019
摘要： A method and apparatus for repairing a damaged intervertebral disc nucleus in a minimally invasive manner utilizes a modular disc prosthesis preferably comprised of at least three modular segments and at least two rails that operably connect adjacent modular segments. In one embodiment, each modular segment includes a harder inner portion and a softer outer portion. Preferably, the rails operate to slidably connect and interlock adjacent modular segments. A stem portion of the rails that extends outside the periphery of the body of the prosthesis is removable after implantation such that the modular segments form an implanted unitary device that closely mimics the geometry of the disc nucleus cavity.
摘要翻译：用于以微创方式修复损伤的椎间盘细胞核的方法和装置利用模块化椎间盘假体，优选地包括至少三个模块化区段和至少两个可操作地连接相邻模块区段的轨道。在一个实施例中，每个模块化区段包括较硬的内部部分和较软的外部部分。优选地，轨道操作以可滑动地连接和互锁相邻的模块段。在植入之后延伸到假体本体周边之外的轨道的茎部分是可去除的，使得模块化部分形成与模腔细胞核的几何形状紧密相似的植入的整体装置。

4. 发明申请

US20080125782A1 METHOD AND APPARATUS FOR REMOVING AN EXTENSION FROM A PROSTHESIS 审中-公开
标题翻译：从扩展中移除扩展的方法和装置
公开(公告)号：US20080125782A1
公开(公告)日：2008-05-29
申请号：US11564708
申请日：2006-11-29
申请人： Mark A. RYDELL , Khin MYINT , Robert Garryl HUDGINS , Erik O. MARTZ
发明人： Mark A. RYDELL , Khin MYINT , Robert Garryl HUDGINS , Erik O. MARTZ
IPC分类号： A61B17/56
CPC分类号： A61B17/32056 , A61B17/8863 , A61F2/441 , A61F2/4611 , A61F2/4637 , A61F2002/30235 , A61F2002/30561 , A61F2002/30583 , A61F2002/4641 , A61F2210/0085 , A61F2230/0069 , A61F2250/0071
摘要： An instrument for cutting an extension, such as a catheter or biomaterial, coupled to a prosthesis, such as a prosthesis located in an intervertebral disc space, that includes at least one axial member having a distal opening and at least one cutting device, such as for example a wire or blade, coupled to the at least one axial member that is capable of moving across at least a portion of the distal opening when a force is applied to the at least one cutting wire. A method for cutting a catheter is also disclosed. The removal instrument may be inserted into an introduction lumen. A force is applied to the at least one cutting device after the catheter is in the distal opening.
摘要翻译：一种用于切割诸如导管或生物材料的延伸件的装置，其耦合到假体，例如位于椎间盘空间中的假体，其包括至少一个具有远端开口的轴向构件和至少一个切割装置，例如例如线或刀片，其耦合到所述至少一个轴向构件，当向所述至少一个切割线施加力时能够移动穿过远端开口的至少一部分。还公开了一种用于切割导管的方法。去除器械可以插入导入管腔中。在导管位于远侧开口中之后，将力施加到至少一个切割装置。

5. 发明授权

US6140452A Biomaterial for in situ tissue repair 失效
标题翻译：用于原位组织修复的生物材料
公开(公告)号：US6140452A
公开(公告)日：2000-10-31
申请号：US195328
申请日：1998-11-18
申请人： Jeffrey C. Felt , Mark A. Rydell , Richard J. Zdrahala , Alexander Arsenyev
发明人： Jeffrey C. Felt , Mark A. Rydell , Richard J. Zdrahala , Alexander Arsenyev
IPC分类号： A61B1/00 , A61B17/00 , A61B17/16 , A61B17/17 , A61B17/88 , A61F2/00 , A61F2/28 , A61F2/30 , A61F2/32 , A61F2/38 , A61F2/40 , A61F2/42 , A61F2/44 , A61F2/46 , A61F2/82 , A61L27/18 , A61L29/04 , A61L29/06 , C08G18/10 , C08G18/48 , C08G18/69
CPC分类号： C08G18/4854 , A61B17/17 , A61F2/30756 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61L27/18 , A61L29/041 , A61L29/06 , C08G18/10 , C08G18/69 , A61B1/00165 , A61B17/00234 , A61B17/16 , A61B17/1671 , A61B17/1675 , A61B2017/00535 , A61F2/07 , A61F2/28 , A61F2/30767 , A61F2/3099 , A61F2/32 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/442 , A61F2/82 , A61F2/945 , A61F2002/30016 , A61F2002/30024 , A61F2002/30235 , A61F2002/30583 , A61F2002/30929 , A61F2002/30957 , A61F2002/4233 , A61F2002/4627 , A61F2002/4635 , A61F2210/0085 , A61F2230/0069 , A61F2250/0019 , A61F2250/0021 , A61L2430/38 , B01F2215/0039
摘要： A method, and related composition and apparatus for repairing a tissue site. The method involves the use of a curable polyurethane biomaterial composition having a plurality of parts adapted to be mixed at the time of use in order to provide a flowable composition and to initiate cure. The flowable composition can be delivered using minimally invasive means to a tissue site and there fully cured provide a permanent and biocompatible prosthesis for repair of the tissue site. Further provided are a mold apparatus, e.g., in the form of a balloon or tubular cavity, for receiving a biomaterial composition, and a method for delivering and filling the mold apparatus with a curable composition in situ to provide a prosthesis for tissue repair.
摘要翻译：一种用于修复组织部位的方法和相关组合物和装置。该方法包括使用可固化的聚氨酯生物材料组合物，其具有适于在使用时混合的多个部分，以提供可流动的组合物并开始固化。可流动组合物可以使用微创手段递送到组织部位，并且完全固化提供用于修复组织部位的永久性和生物相容性假体。还提供了一种用于接收生物材料组合物的气球或管状空腔形式的模具装置，以及用于在原位地递送和填充具有可固化组合物的模具装置以提供用于组织修复的假体的方法。

6. 发明授权

US6079868A Static mixer 失效
标题翻译：静态混合器
公开(公告)号：US6079868A
公开(公告)日：2000-06-27
申请号：US33261
申请日：1998-03-02
申请人： Mark A. Rydell
发明人： Mark A. Rydell
IPC分类号： A61B17/00 , A61F2/30 , A61F2/32 , A61F2/38 , A61F2/40 , A61F2/42 , A61F2/44 , A61F2/46 , A61L27/18 , A61L29/04 , B01F5/06 , B01F13/00 , B01F15/00 , C08G18/10 , C08G18/48 , C08G18/69 , B01F15/02 , A61M5/31 , A61M31/00 , B67D5/60
CPC分类号： A61B17/00491 , A61B17/00234 , A61B17/8816 , A61B17/8833 , A61F2/30756 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61F2/4618 , A61L27/18 , A61L29/041 , B01F13/002 , B01F13/0027 , B01F15/00954 , B01F15/00993 , B01F5/0615 , B01F5/0646 , C08G18/10 , C08G18/4854 , C08G18/69 , A61B17/8822 , A61B17/8827 , A61B2017/00495 , A61B2017/8838 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/442 , A61F2002/30583 , A61F2002/30957 , A61F2002/4233 , A61F2002/4627 , A61F2002/4628 , A61F2002/4635 , A61F2002/465 , A61F2210/0085 , A61L2430/38 , B01F2215/0039
摘要： A device for mixing and delivering a curable biomaterial using minimally invasive techniques. The device provides a mixing path that is configured to contribute a longitudinal distance dimension to the device that is considerably less than the length of the mixing path itself. In so doing, the device can provide improved ergonomic control and single-handed operation in the course of mixing biomaterial components, in order to initiate cure, and delivering the mixed biomaterial through a delivery conduit and to a tissue site in vivo. Optional features of the device include the ability to warm the biomaterial components, to position or retract a protective sheath covering the delivery conduit, and the ability to divert or shunt an initial volume of mixed biomaterial.
摘要翻译：用于使用微创技术混合和递送可固化生物材料的装置。该装置提供了混合路径，该混合路径被配置为向装置贡献远小于混合路径本身的长度的纵向距离尺寸。在这样做时，该装置可以在混合生物材料组件的过程中提供改进的人体工程学控制和单手操作，以便开始固化，并且通过输送管道和体内的组织部位递送混合的生物材料。该装置的可选特征包括加热生物材料部件，定位或缩回覆盖输送导管的保护鞘的能力，以及转移或分流初始体积的混合生物材料的能力。

7. 发明授权

US6042536A Bladder sling 失效
公开(公告)号：US6042536A
公开(公告)日：2000-03-28
申请号：US133596
申请日：1998-08-13
申请人： Claude Tihon , Mark A. Rydell , William P. Ryan
发明人： Claude Tihon , Mark A. Rydell , William P. Ryan
IPC分类号： A61B17/00 , A61B17/02 , A61B17/06 , A61F2/00 , A61F2/02 , A61F5/48
CPC分类号： A61B17/0218 , A61F2/0045 , A61B2017/00805 , A61B2017/0225 , A61B2017/0618
摘要： A sling for supporting the urethra and neck of the bladder to prevent urinary incontinence is disclosed. The sling is designed to provide sufficient support to inhibit the unintended flow of urine, yet stretch in a controlled fashion so that the bladder can be voided at approximate times.

8. 发明授权

US5964751A Light delivery system with blood flushing capability 失效
标题翻译：具有血液冲洗能力的轻型输送系统
公开(公告)号：US5964751A
公开(公告)日：1999-10-12
申请号：US140116
申请日：1998-08-25
申请人： Curtis A. Amplatz , Mark A. Rydell , Robert J. Ziebol , Christopher H. Porter , Michael Kasinkas
发明人： Curtis A. Amplatz , Mark A. Rydell , Robert J. Ziebol , Christopher H. Porter , Michael Kasinkas
IPC分类号： A61B17/22 , A61B18/22 , A61M1/00 , A61M29/02 , A61B17/36
CPC分类号： A61B17/22 , A61B18/22 , A61B2017/22051 , A61B2018/2261 , A61M1/00 , A61M25/104 , A61M29/02
摘要： A light delivery system for use in irradiating vascular tissue includes a balloon catheter with a working lumen for receiving an optical fiber therein and an inflation/flushing lumen adapted to receive a liquid at a proximal end and leading to a space defined within the balloon member attached to a distal end of the catheter. The balloon member has a pattern of holes or pores in the wall thereof through which the saline may flow when the balloon is inflated, causing any blood or other absorbing substances that may interfere with good radiant energy transmission to be flushed away from the treatment site.
摘要翻译：用于照射血管组织的光输送系统包括球囊导管，其具有用于在其中接收光纤的工作腔，以及适于在近端接收液体并且导致限定在所述球囊构件附近的空间的充气/冲洗腔到导管的远端。气球构件在其壁中具有孔或孔的图案，当气囊膨胀时，盐可以通过该孔或孔流动，导致可能干扰良好的辐射能量传递的任何血液或其它吸收物质从治疗部位冲洗掉。

9. 发明授权

US5620438A Method and apparatus for treating vascular tissue following angioplasty to minimize restenosis 失效
标题翻译：用于血管成形术治疗血管组织以最小化再狭窄的方法和装置
公开(公告)号：US5620438A
公开(公告)日：1997-04-15
申请号：US425858
申请日：1995-04-20
申请人： Curtis A. Amplatz , Christopher H. Porter , Mark A. Rydell
发明人： Curtis A. Amplatz , Christopher H. Porter , Mark A. Rydell
IPC分类号： A61B17/00 , A61B17/22 , A61B18/24 , A61M25/00 , A61N5/06 , A61N5/067 , A61N5/10
CPC分类号： A61N5/0601 , A61B18/245 , A61B2017/22002 , A61N2005/0661 , A61N2005/067 , A61N5/1007
摘要： A surgical instrument for treating a blood vessel wall following percutaneous transluminal coronary angioplasty (PTCA) includes an optical system for transmitting radiant energy, preferably UV light energy, from a laser source to the distal end portion a PTCA catheter and causing the radiant energy to exit the catheter in a relatively narrow radial band. A microprocessor-controlled stepping motor is used to longitudinally reposition the band along the length of the balloon of the PTCA catheter to thereby expose endothelial tissue spanned by the balloon to radiation for the purpose of inhibiting smooth muscle proliferation reducing incidences of restenosis.
摘要翻译：用于治疗经皮腔内冠状动脉血管成形术（PTCA）后的血管壁的手术器械包括用于将激光源的辐射能（优选UV光能）从PTCA导管传递到远端部分并使辐射能量退出的光学系统导管在较窄的径向带内。使用微处理器控制的步进电机沿着PTCA导管的气囊的长度纵向地重新定位带，从而将由球囊跨越的内皮组织暴露于辐射，以抑制平滑肌增生，减少再狭窄的发生。

10. 发明授权

US5342359A Bipolar coagulation device 失效
标题翻译：双极凝血装置
公开(公告)号：US5342359A
公开(公告)日：1994-08-30
申请号：US13832
申请日：1993-02-05
申请人： Mark A. Rydell
发明人： Mark A. Rydell
IPC分类号： A61B18/00 , A61B18/14 , A61B17/39
CPC分类号： A61B18/1442 , A61B18/1402 , A61B2018/00982
摘要： A bipolar coagulation instrument comprising three concentric tubes, wherein the outer tube is generally rigid, the central tube is an electrically conductive metal in communication with an energy source, and the inner tube is electrically non-conductive. The distal end of the central tube extends beyond the distal end of the outer tube and functions as an electrode and first jaw of the coagulation instrument. The inner tube, which is translationally movable by an operator, has extending therethrough within its lumen a conductive lead whose distal end protrudes distally therefrom beyond the distal end of the outer tube and is configured at its distal end to function as an opposing second jaw to the first jaw. Translational movement of the inner tube distally forces the second electrode jaw toward the first electrode jaw to thereby bring the first and second jaws into contact with each other. Thereafter, when current is introduced to the conductive lead and to the central tube, the resulting electrode jaws perform to cauterize tissue at the treatment site when such tissue is grasped within the jaws which are then closed. Subsequent proximal translational movement of the inner tube releases the distal end of the conductive lead which is the second jaw of the instrument from the distal end of the central tube which is the first jaw of the instrument. A coagulation instrument is thereby provided whose outer tube has a diameter of less than about three millimeters, thereby permitting its travel within the lumen of a minimally sized laparoscope, endoscope or similar device.
摘要翻译：一种双极凝结仪器，包括三个同心管，其中外管通常是刚性的，中心管是与能量源连通的导电金属，并且内管是非导电的。中心管的远端延伸超过外管的远端，并用作凝结仪器的电极和第一钳口。可由操作者平移移动的内管在其内腔中延伸穿过导电引线，导电引线的远端从外管向远端突出超过外管的远端，并且构造在其远端以用作相对的第二钳口第一颚内管的平移运动向远侧迫使第二电极钳口朝向第一电极钳口，从而使第一和第二钳口相互接触。此后，当电流引入导电引线和中心管时，所产生的电极钳口在将这些组织夹持在钳口内时被处理部位处理部位进行烧灼处理，然后封闭。内管的随后近端平移运动从作为仪器的第一钳口的中心管的远端释放作为仪器的第二钳口的导电引线的远端。因此，提供了一种凝结仪器，其外管具有小于约三毫米的直径，从而允许其在最小尺寸的腹腔镜，内窥镜或类似装置的内腔内行进。

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