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21. 发明授权

US07457636B2 Self defense cellular telephone 失效
标题翻译：自卫手机
公开(公告)号：US07457636B2
公开(公告)日：2008-11-25
申请号：US10219901
申请日：2002-08-14
申请人： Chase R. Kroll , Mark W. Kroll
发明人： Chase R. Kroll , Mark W. Kroll
IPC分类号： H04B1/38
CPC分类号： H04M1/21 , H04B1/3833 , H04M1/0287 , H04M1/18 , H04M1/677 , H04M1/6775 , H04M1/72519 , H04M1/72538 , H04M1/72541 , H04M15/765 , H04M15/77 , H04M15/8083 , H04M17/005 , H04M2215/0184 , H04M2215/32 , H04M2215/724 , H04M2215/7254 , H04M2250/10 , H04M2250/12
摘要： The present invention teaches an economical disposable emergency cellular telephone. A major object of this invention is a cellular telephone providing a self-defense capability to a user by generating high voltage shocks. A further object of the invention is a new technique for having a large number of cellular phones share the same small group of access numbers and serial numbers in order to reduce the monthly charges to zero for the end consumer. This makes it more practical to use cellular phones for data transmission and monitoring applications.
摘要翻译：本发明教导了一种经济的一次性紧急蜂窝电话。本发明的主要目的是通过产生高电压冲击向用户提供自卫能力的蜂窝电话。本发明的另一个目的是一种用于使大量蜂窝电话共享相同的小组接入号码和序列号以便为最终消费者将每月收费减少到零的新技术。这使得使用蜂窝电话进行数据传输和监控应用更为实用。

22. 发明授权

US07450995B2 Implantable cardiac stimulation device including an output circuit that provides arbitrarily shaped defibrillation waveforms 有权
标题翻译：可植入心脏刺激装置，包括提供任意形状除颤波形的输出电路
公开(公告)号：US07450995B2
公开(公告)日：2008-11-11
申请号：US10687386
申请日：2003-10-15
申请人： J. Christopher Moulder , Gabriel A. Mouchawar , Steven W. Badelt , Mark W. Kroll
发明人： J. Christopher Moulder , Gabriel A. Mouchawar , Steven W. Badelt , Mark W. Kroll
IPC分类号： A61N1/40
CPC分类号： H03F3/217 , A61N1/3975 , A61N1/3981
摘要： An output circuit for use in an implantable cardiac defibrillation provides an output pulse having a waveform of virtually any desired shape. The device includes a sensing circuit that senses cardiac activity. An arrhythmia detector detects fibrillation responsive to the cardiac activity signal. The device further includes an output circuit that provides a stimulation output pulse when the arrhythmia detector detects a cardiac arrhythmia. The output circuit includes an H-bridge having a pair of switching devices which control the output pulse waveform with pulse-width modulation and a second pair of switching devices that control the output pulse polarity.
摘要翻译：用于可植入心脏除颤的输出电路提供具有几乎任何期望形状的波形的输出脉冲。该装置包括感测心脏活动的感测电路。心律失常检测器响应于心脏活动信号检测原纤维。该装置还包括输出电路，其在心律不齐检测器检测到心律不齐时提供刺激输出脉冲。输出电路包括H桥，其具有控制脉冲宽度调制的输出脉冲波形的一对开关器件和控制输出脉冲极性的第二对开关器件。

23. 发明授权

US07447544B1 System and method for controlling the recording of diagnostic medical data in an implantable medical device 有权
公开(公告)号：US07447544B1
公开(公告)日：2008-11-04
申请号：US10782123
申请日：2004-02-18
申请人： Mark W. Kroll
发明人： Mark W. Kroll
IPC分类号： A61N1/37
CPC分类号： A61N1/362 , A61N1/025 , A61N1/3621
摘要： Techniques are provided for controlling the recording of diagnostic data, such as intracardiac electrogram (IEGM) data, so as to reduce device power consumption. In one technique, the risk of onset of an arrhythmia is evaluated and the recording of diagnostic data is then selectively controlled based upon the evaluation. More specifically, a temporary “pre-trigger” memory for recording IEGM data is activated only at times when there is a significant risk that an arrhythmia will actually occur. Power savings are thereby achieved as compared to devices that require the pre-trigger memory to be continuously active. In another technique, parameters employed to trigger the recording of diagnostic data are adaptively modified to reduce the likelihood of any unnecessary recording of such data. Preferably, both the risk-based techniques and the adaptive techniques are implemented in the same system.

24. 发明授权

US07414534B1 Method and apparatus for monitoring ingestion of medications using an implantable medical device 有权
标题翻译：用于使用可植入医疗装置监测摄取药物的方法和装置
公开(公告)号：US07414534B1
公开(公告)日：2008-08-19
申请号：US10985298
申请日：2004-11-09
申请人： Mark W. Kroll , Alan B. Vogel
发明人： Mark W. Kroll , Alan B. Vogel
IPC分类号： G08B23/00
CPC分类号： G06F19/3456 , A61B5/0031 , A61B5/076 , A61B5/1116 , A61B5/1123 , A61B5/4205 , A61B5/4833 , A61B5/4839 , A61B7/008 , A61B90/90 , A61B90/98 , A61B2562/0219 , A61N1/365 , G06F19/00 , Y10S128/903
摘要： An implantable medical device, such as a pacemaker or implantable cardioverter defibrillator (ICD), is configured to automatically detect ingestion of medications to verify that prescribed medications are taken in a timely manner and at the correct dosage. Briefly, individual pills are provided with miniature radio frequency identification (RFID) devices capable of transmitting RFID tag signals, which identify the medication contained within the pill and its dosage. The implanted device is equipped with an RFID transceiver for receiving tag signals from a pill as it is being ingested. The implanted system decodes the tag to identify the medication and its dosage, then accesses an onboard database to verify that the medication being ingested was in fact prescribed to the patient and to verify that the correct dosage was taken. Warning signals are generated if the wrong medication or the wrong dosage was taken. Therapy may also be automatically adjusted. Non-RF-based ID devices are also described, which instead transmit ID data via biphasic current pulses.
摘要翻译：诸如起搏器或植入式心律转复除颤器（ICD）的可植入医疗装置被配置为自动检测药物的摄取以验证是否及时以正确的剂量服用规定的药物。简而言之，单独的药丸配备有能够发送RFID标签信号的微型射频识别（RFID）设备，其识别药物中所含的药物及其剂量。植入装置配备有RFID收发器，用于在被摄取时从药片接收标签信号。植入系统解码标签以识别药物及其剂量，然后访问车载数据库以验证被摄取的药物实际上已经被给予患者并验证正确的剂量是否被采取。如果使用了错误的药物或错误的剂量，就会产生警告信号。治疗也可以自动调整。还描述了基于非RF的ID设备，其代替通过双相电流脉冲发送ID数据。

25. 发明授权

US07412285B2 Method and device for treating cancer with electrical therapy in conjunction with chemotherapeutic agents and radiation therapy 有权
标题翻译：用化学疗法和放射治疗联合电疗治疗癌症的方法和装置
公开(公告)号：US07412285B2
公开(公告)日：2008-08-12
申请号：US10434400
申请日：2003-05-07
申请人： Edward A. Schroeppel , Mark W. Kroll , Kai Kroll
发明人： Edward A. Schroeppel , Mark W. Kroll , Kai Kroll
IPC分类号： A61N1/00
CPC分类号： A61N1/326 , A61K47/6957 , A61N1/205 , A61N1/30
摘要： This invention relates generally to the electrical treatment of malignant tumors and neoplasms by applying a voltage to affected tissue. Devices and various adaptations therein are described for use in electrical therapy. Additionally, various chemotherapeutic agent and radiation therapies are described which may be advantageously used in conjunction with electrical therapy to ameliorate cancer.
摘要翻译：本发明一般涉及通过向受影响的组织施加电压来恶性肿瘤和肿瘤的电处理。描述了其中的装置和各种适应性用于电疗法。另外，描述了可以有利地与电疗法一起使用以改善癌症的各种化学治疗剂和放射疗法。

26. 发明授权

US07386343B1 Spectrum-driven arrhythmia treatment method 有权
标题翻译：频谱驱动心律失常治疗方法
公开(公告)号：US07386343B1
公开(公告)日：2008-06-10
申请号：US11240950
申请日：2005-09-30
申请人： Mark W. Kroll , Peter Boileau
发明人： Mark W. Kroll , Peter Boileau
IPC分类号： A61N1/36
CPC分类号： A61N1/3622
摘要： A method and apparatus for treating an arrhythmia is provided. The method includes the steps of: (a) sensing at least one electrical signal from the patient's heart; (b) calculating a frequency spectrum of each electrical signal; (c) calculating a center frequency for each frequency spectrum; and (d) selecting an electro-therapy for delivery to the patient's heart based on the center frequency. The electro-therapy can be a pre-programmed anti-tachycardia pacing (ATP) therapy, a shock therapy, or no therapy at all. The method is performed through the use of an implantable cardioverter defibrillator (ICD). Also provided is a method of determining the optimal location to deliver the electro-therapy.
摘要翻译：提供了一种治疗心律失常的方法和装置。该方法包括以下步骤：（a）感测来自患者心脏的至少一个电信号; （b）计算每个电信号的频谱; （c）计算每个频谱的中心频率; 以及（d）根据中心频率选择电疗以传送到患者的心脏。电疗可以是预先编程的抗心动过速起搏（ATP）治疗，休克疗法，或根本没有治疗。该方法通过使用植入式心律转复除颤器（ICD）进行。还提供了确定递送电疗的最佳位置的方法。

27. 发明申请

US20080061278A1 Toddler stair safety system 有权
标题翻译：蹒跚学步楼梯安全系统
公开(公告)号：US20080061278A1
公开(公告)日：2008-03-13
申请号：US11519678
申请日：2006-09-12
申请人： Lori C. Kroll , Mark W. Kroll
发明人： Lori C. Kroll , Mark W. Kroll
IPC分类号： E04H17/16
CPC分类号： E04F11/1863
摘要： A major object of this invention is the use of a heavy net with an optimally sized mesh that provides an easy gripping surface for a toddler hands with no choking or entrapment hazards. A further object of this invention is to provide a method of providing tension securement to a carpeted surface by the use of deep-machined hook surfaces.Another object of this invention is to teach the use of fastening a net to an existing banister by the use of hook and loop fasteners. Another object of this invention is to teach the manufacture of a carpeted stair gripper, which allows objects to be attached, and custom fitted, to the edges of carpeted stair steps with great strength and with no tools or defacement of the stairs.
摘要翻译：本发明的主要目的是使用具有最佳尺寸的网格的重型网，其为幼儿手提供容易的抓握表面，而没有阻塞或夹带危险。本发明的另一个目的是提供一种通过使用深加工的钩表面向地毯表面提供张力固定的方法。本发明的另一个目的是教导通过使用钩环紧固件将网固定到现有的栏杆上的用途。本发明的另一个目的是教导一种铺有地毯的楼梯夹持器的制造，其允许物体以很大的强度和没有工具或楼梯的污损被附着和定制安装在地毯阶梯台阶的边缘上。

28. 发明授权

US07333854B1 Orthostatic cardiac output response pacer for heart failure patients and diabetic patients 有权
标题翻译：心力衰竭患者和糖尿病患者的正常心输出量反应发作
公开(公告)号：US07333854B1
公开(公告)日：2008-02-19
申请号：US11048251
申请日：2005-01-31
申请人： James E. Brewer , Mark W. Kroll
发明人： James E. Brewer , Mark W. Kroll
IPC分类号： A61N1/00
CPC分类号： A61N1/3627 , A61N1/36542
摘要： An exemplary method includes detecting a change in position, measuring cardiac output after the detecting a change in position and, based at least in part on the measuring cardiac output, deciding whether to increase a cardiac pacing rate. An exemplary method may rely on activity in lieu of or in addition to position to decide whether to increase a cardiac pacing rate. Various exemplary methods aim to compensate for orthostatic effects such as those associated with dysautonomia. Various other exemplary methods are disclosed along with various exemplary devices, systems, etc.
摘要翻译：示例性方法包括检测位置变化，在检测到位置变化之后测量心输出量，并且至少部分地基于测量心输出量来决定是否增加心脏起搏速率。示例性方法可以依赖于代替或除了位置之外的活动以决定是否增加心脏起搏速率。各种示例性方法旨在补偿诸如与自主神经病相关的直立效应。公开了各种其它示例性方法以及各种示例性装置，系统等

29. 发明授权

US07308305B1 Optimally timed early shock defibrillation 失效
标题翻译：最佳定时早期震颤除颤
公开(公告)号：US07308305B1
公开(公告)日：2007-12-11
申请号：US10901480
申请日：2004-07-27
申请人： Rose Province , Mark W. Kroll
发明人： Rose Province , Mark W. Kroll
IPC分类号： A61N1/39
CPC分类号： A61N1/3987
摘要： An exemplary method includes detecting two or more event interval times associated with an arrhythmic condition, averaging event interval times to provide an average event interval time, providing a fraction and calling for delivery of an anti-arrhythmia shock at a delivery time based on the fraction and the average event interval time. In this exemplary method, the events optionally correspond to early coarse ventricular fibrillation events and the delivery time is optionally less than about three seconds from the detecting of a first event of a first event interval time. Other exemplary methods, devices, systems, etc., are also disclosed.
摘要翻译：示例性方法包括检测与心律失常状况相关联的两个或更多个事件间隔时间，平均事件间隔时间以提供平均事件间隔时间，提供分数，并且基于分数来提供递送时间的抗心律失常休克的递送和平均事件间隔时间。在该示例性方法中，事件可选地对应于早期的粗心室颤动事件，并且递送时间可选地从检测第一事件间隔时间的第一事件小于约三秒。还公开了其它示例性方法，装置，系统等。

30. 发明授权

US07231255B1 System and method for reducing pain associated with cardioversion shocks generated by implantable cardiac stimulation devices 有权
标题翻译：用于减轻由可植入心脏刺激装置产生的心脏复律冲击相关疼痛的系统和方法
公开(公告)号：US07231255B1
公开(公告)日：2007-06-12
申请号：US10855840
申请日：2004-05-26
申请人： Mark W. Kroll , Gabriel A. Mouchawar
发明人： Mark W. Kroll , Gabriel A. Mouchawar
IPC分类号： A61N1/34 , A61N1/38 , A61N1/39
CPC分类号： A61N1/3906 , A61N1/36071
摘要： Techniques are provided for generating pre-pulse pain inhibition (PPI) pulses and subsequent main cardioversion shocks. The PPI pulses are relatively low-voltage pulses each having a chevron-shaped waveform. The main shocks are relatively high-voltage shocks each having a plateau-shaped waveform. By employing plateau-shaped waveforms for the main shocks, a greater cardiac membrane response can be achieved at an equivalent peak voltage as compared to conventional shock waveforms. Peak voltage is a significant contributor to pain caused by cardioversion shocks. Hence, by using the plateau-shaped waveform, pain reduction can be achieved without loss of shock effectiveness. Moreover, by employing chevron-shaped PPI pulses in combination with plateau-shaped main shocks, a relatively simple shocking circuit having a single high-voltage shocking capacitor may be used, thus eliminating the need for both low-voltage PPI capacitors and higher voltage main shock capacitors. The shocking circuit includes a low-pass resistive-capacitive filter.
摘要翻译：提供了用于产生预脉冲疼痛抑制（PPI）脉冲和随后的主复律冲击的技术。 PPI脉冲是具有V形波形的相对低电压脉冲。主要的冲击是具有平台状波形的相对高压冲击。通过采用平台状波形作为主要冲击，与常规冲击波形相比，可以在等效峰值电压下获得更大的心脏膜响应。峰值电压是心脏复律冲击引起的疼痛的重要原因。因此，通过使用平台状波形，可以实现疼痛减轻而不损失冲击效果。此外，通过采用人字形PPI脉冲与平台形主冲击结合，可以使用具有单个高压冲击电容器的相对简单的冲击电路，因此不需要两个低压PPI电容器和较高电压主冲击电容器。令人震惊的电路包括一个低通电阻滤波器。

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