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21. 发明授权

US5936248A Multiple energy scintillation camera spatial correction method and apparatus 失效
标题翻译：多能量闪烁摄像机空间校正方法及装置
公开(公告)号：US5936248A
公开(公告)日：1999-08-10
申请号：US2200
申请日：1997-12-31
申请人： Floribertus P. M. Heukensfeldt Jansen
发明人： Floribertus P. M. Heukensfeldt Jansen
IPC分类号： G01T1/164
CPC分类号： G01T1/1642 , G01T1/1647 , A61B6/4258
摘要： A method for use with a scintillation camera which detects radiation events having energies within two different energy ranges and distorts spatial coordinates of detected events in the two ranges differently, a spatial coordinate set is determined for each event, each coordinate set is adjusted using a first set of predetermined correction factors calculated to eliminate distortion in events within a first of the energy ranges yielding first corrected coordinate sets corresponding to events within the first energy range and adjusted sets corresponding to events within the second energy range, adjusted sets are further adjusted using a second set of predetermined correction factors calculated to eliminate distortion in the adjusted sets yielding corrected second sets, the first and second sets are then used to generate first and second images, respectively.
摘要翻译：一种与闪烁照相机一起使用的方法，其检测在两个不同能量范围内具有能量的辐射事件，并且在两个范围内扭曲检测事件的空间坐标不同，为每个事件确定空间坐标集，每个坐标集使用第一计算出的预定校正因子的集合以消除在第一能量范围内的事件中的失真，产生与第一能量范围内的事件相对应的第一校正坐标集，以及对应于第二能量范围内的事件的调整集合，调整后的集合使用计算出的第二组预定校正因子以消除经校正的第二组的调整组中的失真，然后第一组和第二组分别用于产生第一和第二图像。

22. 发明申请

US20140064456A1 MOTION CORRECTION SYSTEM AND METHOD FOR AN X-RAY TUBE 有权
标题翻译：运动校正系统和X射线管的方法
公开(公告)号：US20140064456A1
公开(公告)日：2014-03-06
申请号：US13602080
申请日：2012-08-31
申请人： Yun Zou , Scott Stephen Zelakiewicz , Floribertus P. M. Heukensfeldt Jansen , Jeffrey Wayne Eberhard , Fengfeng Tao , Timothy Powers , Thomas Edmund Sjoberg
发明人： Yun Zou , Scott Stephen Zelakiewicz , Floribertus P. M. Heukensfeldt Jansen , Jeffrey Wayne Eberhard , Fengfeng Tao , Timothy Powers , Thomas Edmund Sjoberg
IPC分类号： H01J35/30
CPC分类号： H01J35/28 , H01J35/025 , H01J35/14
摘要： A motion correction system and method for motion correction for an x-ray tube is presented. One embodiment of the motion correction system includes a sensing unit coupled to an x-ray tube to determine a distance with which an impingement location of an electron beam generated by the x-ray tube deviates from a determined location due to motion of the x-ray tube. The motion correction system further includes a control unit coupled to the sensing unit to generate a control signal corresponding to the distance with which the impingement location of the electron beam deviates. Also, the motion correction system includes a deflection unit coupled to the control unit to steer the electron beam to the determined location based on the generated control signal.
摘要翻译：提出了用于X射线管的运动校正系统和运动校正方法。运动校正系统的一个实施例包括耦合到X射线管的感测单元，以确定由x射线管产生的电子束的冲击位置由于X射线管的运动而偏离确定的位置的距离，射线管。运动校正系统还包括耦合到感测单元的控制单元，以产生对应于电子束的冲击位置偏离的距离的控制信号。此外，运动校正系统包括耦合到控制单元的偏转单元，以基于所生成的控制信号将电子束转向确定的位置。

23. 发明申请

US20130284939A1 METHOD AND SYSTEM FOR NON-INVASIVE IMAGING OF A TARGET REGION 有权
标题翻译：目标区域非侵入式成像的方法和系统
公开(公告)号：US20130284939A1
公开(公告)日：2013-10-31
申请号：US13459585
申请日：2012-04-30
申请人： Bruno Kristiaan Bernard DeMan , James Vradenburg Miller , Floribertus P. M. Heukensfeldt Jansen
发明人： Bruno Kristiaan Bernard DeMan , James Vradenburg Miller , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： G01T1/16
CPC分类号： A61B6/032 , A61B6/037 , A61B6/06 , A61B6/12 , A61B6/4021 , A61B6/4241 , A61B6/4417 , A61B6/469 , A61B6/482 , A61B6/488 , G06T11/005
摘要： Embodiments of systems, methods and non-transitory computer readable media for imaging are presented. Preliminary image data corresponding to a first FOV of a subject at a first resolution is acquired using an imaging system including one or more radiation sources and at least one hybrid detector, specifically using at least one section of the hybrid detector having the first resolution. The target ROI is identified using the preliminary image data. Further, the subject is positioned to align the target ROI along a designated axis. Additionally, parameters associated with the sources, the hybrid detector and/or an imaging system gantry are configured for acquiring target image data at a second resolution greater than the first resolution using at least one section of the hybrid detector having the second resolution. Further, one or more images corresponding to at least the target ROI are reconstructed using the target and/or the preliminary image data.
摘要翻译：提出了用于成像的系统，方法和非暂时计算机可读介质的实施例。使用包括一个或多个辐射源和至少一个混合检测器的成像系统，特别是使用具有第一分辨率的混合检测器的至少一个部分，获取与第一分辨率的对象的第一FOV相对应的初步图像数据。使用初步图像数据来识别目标ROI。此外，被摄体被定位成沿着指定轴对准目标ROI。另外，与源相关联的参数，混合检测器和/或成像系统台架被配置为使用具有第二分辨率的混合检测器的至少一个部分以大于第一分辨率的第二分辨率来获取目标图像数据。此外，使用目标和/或初步图像数据来重构与至少目标ROI相对应的一个或多个图像。

24. 发明授权

US08487265B2 Imaging detector and method of manufacturing 有权
标题翻译：成像探测器和制造方法
公开(公告)号：US08487265B2
公开(公告)日：2013-07-16
申请号：US13304248
申请日：2011-11-23
申请人： Floribertus P. M. Heukensfeldt Jansen , Yaron Hefetz
发明人： Floribertus P. M. Heukensfeldt Jansen , Yaron Hefetz
IPC分类号： H01L27/146
CPC分类号： H01L31/085 , A61B6/037 , A61B6/06 , A61B6/42
摘要： Imaging detectors and methods of manufacturing are provided. One imaging detector includes a first detector layer within a detector module and a second detector layer within the detector module and spaced apart from the first detector layer, wherein the second detector layer has an opening therethrough. The imaging detector also includes a collimator mounted to the detector module, wherein the collimator is one of a single pinhole collimator or a multi-pinhole collimator. Additionally, the second detector layer is mounted within the detector module closer to an opening of the collimator than the first detector layer.
摘要翻译：提供成像探测器和制造方法。一个成像检测器包括检测器模块内的第一检测器层和检测器模块内的第二检测器层并且与第一检测器层间隔开，其中第二检测器层具有穿过其中的开口。成像检测器还包括安装到检测器模块的准直器，其中准直器是单个针孔准直仪或多针孔准直仪之一。此外，第二检测器层安装在检测器模块内比第一检测器层更靠近准直仪的开口。

25. 发明授权

US08415632B2 Methods and systems for calibrating a nuclear medicine imaging system 有权
标题翻译：用于校准核医学成像系统的方法和系统
公开(公告)号：US08415632B2
公开(公告)日：2013-04-09
申请号：US12720451
申请日：2010-03-09
申请人： Leonid Tsukerman , Floribertus P. M. Heukensfeldt Jansen , Ira Blevis , Jean-Paul Bouhnik
发明人： Leonid Tsukerman , Floribertus P. M. Heukensfeldt Jansen , Ira Blevis , Jean-Paul Bouhnik
IPC分类号： G01T1/161
CPC分类号： G01T1/1647 , G01T7/005
摘要： Methods and systems for calibrating a nuclear medicine imaging system are provided. One method includes acquiring spatially determined non-uniform radiation flux information from a calibration scan of a calibration source using a gamma camera having an attached non-parallel-hole collimator. The method further includes determining a measured non-uniform count density profile from the acquired non-uniform radiation flux information. The method also includes creating a gamma camera uniformity correction map derived from (i) the measured non-uniform count density profile and (ii) a modeled or calculated non-uniform count density profile for calibrating the NM imaging system.
摘要翻译：提供了用于校准核医学成像系统的方法和系统。一种方法包括使用具有附接的非平行孔准直器的伽马照相机从校准源的校准扫描获取空间上确定的不均匀辐射通量信息。该方法还包括从所获取的非均匀辐射通量信息确定测量的不均匀计数密度分布。该方法还包括创建从（i）测量的非均匀计数密度分布和（ii）用于校准NM成像系统的建模或计算的不均匀计数密度分布导出的伽马相机均匀性校正图。

26. 发明申请

US20120080414A1 METHOD AND SYSTEM FOR LASER PATTERNING A SEMICONDUCTOR SUBSTRATE 审中-公开
标题翻译：用于激光扫描半导体衬底的方法和系统
公开(公告)号：US20120080414A1
公开(公告)日：2012-04-05
申请号：US12894416
申请日：2010-09-30
申请人： Wenwu Zhang , Christopher James Kapusta , Floribertus P. M. Heukensfeldt Jansen , Kristian William Andreini , Vladimir A. Lobastov , Kristen Ann Wangerin , Jun Cui
发明人： Wenwu Zhang , Christopher James Kapusta , Floribertus P. M. Heukensfeldt Jansen , Kristian William Andreini , Vladimir A. Lobastov , Kristen Ann Wangerin , Jun Cui
IPC分类号： B23K26/00
CPC分类号： B23K26/0624 , B23K26/0604 , B23K26/064 , B23K26/082 , B23K26/0853 , B23K26/364 , B23K26/40 , B23K26/53 , B23K2101/34 , B23K2101/40 , B23K2103/172 , B23K2103/50 , B23K2103/56
摘要： A method for laser patterning a sample is presented. The method includes coating at least one side of a substrate to form a sample, where coating the at least one side of the substrate forms an interface between the coating and the at least one side of the substrate. Further, the method includes configuring a scanning pattern for patterning the sample. In addition, the method includes determining settings for one or more laser beams of a laser based on the configured scanning pattern. Moreover, the method includes focusing the one or more laser beams of the laser at or near a surface of the substrate by selecting a focal point of the one or more laser beams near the surface of the substrate and setting a scribe depth near the surface of the substrate. The method also includes patterning the sample based on the configured scanning pattern using the one or more laser beams to generate one or more pixelated devices from the sample.
摘要翻译：提出了一种用于激光图案化样品的方法。该方法包括涂覆基底的至少一侧以形成样品，其中涂覆基底的至少一侧形成涂层和基底的至少一侧之间的界面。此外，该方法包括配置用于图案化样品的扫描图案。另外，该方法包括基于配置的扫描图案来确定激光器的一个或多个激光束的设置。此外，该方法包括通过选择基板表面附近的一个或多个激光束的焦点，将基板的表面附近的激光束的一个或多个激光束聚焦在基板的表面附近，底物。该方法还包括使用一个或多个激光束基于配置的扫描图案图案化样品，以从样品生成一个或多个像素化装置。

27. 发明授权

US08103329B2 System and method for imaging based on ultrasonic tagging of light 有权
标题翻译：基于超声波标记的成像系统和方法
公开(公告)号：US08103329B2
公开(公告)日：2012-01-24
申请号：US11254266
申请日：2005-10-20
申请人： Pavel Alexeyevich Fomitchov , Kajoli Banerjee Krishnan , Stephen Johnson Lomnes , Floribertus P. M. Heukensfeldt Jansen
发明人： Pavel Alexeyevich Fomitchov , Kajoli Banerjee Krishnan , Stephen Johnson Lomnes , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： A61B5/05
CPC分类号： G01N21/6456 , A61B5/0051 , A61B5/0091 , A61B5/4312 , A61K49/0017 , A61K49/0032 , A61K49/0034 , B82Y5/00 , B82Y10/00 , B82Y20/00 , G01N21/1717 , G01N21/4795 , G01N2021/1729 , G01N2021/6439
摘要： A technique is provided for imaging based on localization of fluorescence in a medium. The technique includes illuminating the medium with an excitation light to excite fluorescence, scanning the medium at a plurality of locations via an ultrasonic beam, modulating a portion of the emitted light from the fluorescence via the ultrasonic beam at each of the plurality of locations, differentially detecting the modulated light at a boundary of the medium, and reconstructing an image from the detected signal.
摘要翻译：提供了一种基于荧光在介质中定位的成像技术。该技术包括用激发光照射介质以激发荧光，通过超声波束在多个位置扫描介质，在多个位置的每一个处经由超声波束在荧光上调制一部分发射的光检测介质边界处的调制光，并根据检测到的信号重建图像。

28. 发明授权

US07723690B2 Adjustable slit collimators method and system 有权
标题翻译：可调节准直器的方法和系统
公开(公告)号：US07723690B2
公开(公告)日：2010-05-25
申请号：US11731873
申请日：2007-03-30
申请人： Jorge Uribe , James William Hugg , Floribertus P. M. Heukensfeldt Jansen
发明人： Jorge Uribe , James William Hugg , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： G01T1/166 , G01T1/16
CPC分类号： G21K1/025 , A61B6/032 , A61B6/037 , A61B6/06
摘要： Embodiments relate to a slit collimator assembly including a first set of panels spaced at least partially around a longitudinal axis of the collimator assembly and extending generally parallel to the longitudinal axis. The slit collimator assembly further includes a second set of panels spaced at least partially around longitudinal axis of the collimator assembly and extending generally parallel to the longitudinal axis. The first set of panels and the second set of panels are arranged to define one or more slit apertures. The slit collimator assembly is configured so that movement of at least one of the first set of panels or the second set of panels adjusts an aperture size of at least one of the one or more slit apertures. The slit collimator assembly is configured so that gamma rays can pass through the one or more slit apertures, but the remainder of the collimator assembly is substantially gamma ray absorbent. Embodiments also relate to imaging systems and methods of changing collimator performance.
摘要翻译：实施例涉及一种狭缝准直器组件，其包括至少部分围绕准直器组件的纵向轴线间隔开并且大致平行于纵向轴线延伸的第一组面板。狭缝准直器组件还包括至少部分地围绕准直器组件的纵向轴线间隔开并且大致平行于纵向轴线延伸的第二组面板。第一组面板和第二组面板被布置成限定一个或多个狭缝孔。狭缝准直器组件被配置为使得第一组面板或第二组面板中的至少一个的移动调节一个或多个狭缝孔中的至少一个的孔径尺寸。狭缝准直器组件被配置成使得γ射线可以穿过一个或多个狭缝孔，但准直器组件的其余部分基本上是γ射线吸收剂。实施例还涉及成像系统和改变准直仪性能的方法。

29. 发明授权

US07470907B2 Cross-slit collimator method and system 有权
公开(公告)号：US07470907B2
公开(公告)日：2008-12-30
申请号：US11639786
申请日：2006-12-15
申请人： James William Hugg , Jorge Uribe , Floribertus P. M. Heukensfeldt Jansen
发明人： James William Hugg , Jorge Uribe , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： G01T1/20
CPC分类号： G21K1/04 , A61B6/032 , A61B6/037
摘要： Collimator assemblies that include an outer slit collimator having one or more slits therein, and an inner slit collimator having one or more slits therein are provided. Imaging systems that include a collimator assembly and a detector array are also provided. The collimator assembly includes an outer slit collimator having one or more slits therein. The collimator assembly further includes an inner slit collimator having one or more slits therein. The imaging system also includes a detector array configured to detect gamma rays emanating from a field of view that pass through one or more apertures defined by the collimator assembly. The detector array is further configured to generate one or more signals in response to the detected gamma rays. Methods of imaging a field of view using the imaging system are also provided.

30. 发明授权

US6051837A Gamma camera stabilizer 有权
标题翻译：伽玛相机稳定器
公开(公告)号：US6051837A
公开(公告)日：2000-04-18
申请号：US400598
申请日：1999-09-21
申请人： Floribertus P. M. Heukensfeldt Jansen
发明人： Floribertus P. M. Heukensfeldt Jansen
IPC分类号： G01T1/164 , G01T1/208
CPC分类号： G01T1/1648
摘要： A method for identifying PMT drift in an edge PMT of a gamma camera, where said gamma camera includes a plurality of PMTs arranged in an array. The central point of said array generates an intensity signal M during a flood procedure and a field of view edge blocks a portion of the edge PMT. The PMT intensity profile changes due to the blocked PMT portion and contains a first point at which the intensity level is N, where N is a fraction of M.
摘要翻译：一种用于识别γ照相机的边缘PMT中的PMT漂移的方法，其中所述伽马照相机包括以阵列排列的多个PMT。所述阵列的中心点在洪泛过程期间产生强度信号M，并且视野边缘阻挡边缘PMT的一部分。 PMT强度分布由于PMT部分被阻塞而变化，并且包含强度水平为N的第一点，其中N是M的分数。

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