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21. 发明授权

US4073102A Premanufactured modular town house building construction 失效
标题翻译：预制模块化联排别墅建筑施工
公开(公告)号：US4073102A
公开(公告)日：1978-02-14
申请号：US364808
申请日：1973-05-29
申请人： John S. Fisher
发明人： John S. Fisher
IPC分类号： E04B1/348 , E04B1/34
CPC分类号： E04B1/34823
摘要： A modular building construction system having (a) a series of rectangular U-shaped in vertical cross-section modules, each having only two bearing walls opposite each other and joined by a floor panel and open on top, and (b) a series of rectangular tube-shaped in vertical cross-section modules, each having only two bearing walls opposite each other and joined by both a floor panel and a ceiling panel. The tube-shaped modules are used only on the top story, and the U-shaped modules are used generally as lower units. The modules on each level are installed end to end so as to form a continuous living space in the longitudinal direction and side by side so as to form a separate series of living spaces and double walls separating the living spaces in the transverse direction.
摘要翻译：一种模块化建筑施工系统，其具有（a）一系列矩形的U形垂直横截面模块，每个模块仅具有彼此相对的两个轴承壁，并通过底板连接并在顶部开口，以及（b）一系列矩形管状的垂直横截面模块，每个仅具有彼此相对的两个轴承壁，并通过地板镶板和天花板面板连接。管状模块仅用于上层故障，U形模块通常用作较低单元。各级的模块端对端地安装，以便在纵向和并排上形成连续的生活空间，以形成分开的一系列生活空间和在横向上分隔居住空间的双层壁。

22. 发明授权

US08939910B2 Method for enhancing ultrasound visibility of hyperechoic materials 有权
标题翻译：提高高回声材料超声能见度的方法
公开(公告)号：US08939910B2
公开(公告)日：2015-01-27
申请号：US11277721
申请日：2006-03-28
申请人： John S. Fisher
发明人： John S. Fisher
IPC分类号： A61B8/14 , A61B8/00 , A61F2/02 , A61B19/00
CPC分类号： A61B90/39 , A61B2090/3908 , A61B2090/3925 , A61B2090/3995 , A61F2/02 , A61K49/226 , A61L31/06 , A61L31/145
摘要： A hydrogel marker is placed under stress during its curing stage, in one embodiment, by application of an externally applied force. The stress may also be induced during or after the dehydration process. The direction of the externally applied force increases the length, width, depth, or radial extent of the marker. The elastic limit of the marker is exceeded when the external force is applied so that the marker substantially retains its stressed size and shape when the externally applied force is removed. When the stretched or otherwise deformed dehydrated marker is hydrated, it substantially returns to the configuration it had prior to its dehydration and prior to the application of the externally applied force.
摘要翻译：水凝胶标记物在其固化阶段处于应力状态，在一个实施方案中，通过施加外部施加的力。也可能在脱水过程中或之后引起应力。外部施加力的方向增加了标记的长度，宽度，深度或径向范围。当施加外力时，超过标记的弹性极限，使得当外部施加的力被去除时，标记基本上保持其应力尺寸和形状。当拉伸或变形的脱水标记水合时，其基本上返回到其脱水之前并且在施加外部施加的力之前具有的构型。

23. 发明授权

US08183889B2 Common-mode insensitive sampler 有权
标题翻译：共模不敏感取样器
公开(公告)号：US08183889B2
公开(公告)日：2012-05-22
申请号：US12869234
申请日：2010-08-26
申请人： Lawrence J. Kushner , Michael P. Anthony , John S. Fisher
发明人： Lawrence J. Kushner , Michael P. Anthony , John S. Fisher
IPC分类号： G11C27/02
CPC分类号： H03M1/0636 , H03M1/1245
摘要： An approach to rejecting input common-mode voltage variations in a sampler/converter that avoids the use of a differential amplifier in the signal path, and without introducing added distortion or noise. In one embodiment, the input common-mode variations are sensed on a pair of matched resistors that straddle the common mode analog inputs, on a node ‘Vcmi’. An alternative, switched-capacitor-based sensing scheme is also possible. Using this measured Vcmi, adjustments are then made to the rest of the sampler/converter to take out any variations observed at Vcmi.
摘要翻译：拒绝采样器/转换器中的输入共模电压变化的方法，其避免在信号路径中使用差分放大器，并且不引入附加的失真或噪声。在一个实施例中，在节点“Vcmi”上跨越共模模拟输入的一对匹配电阻上感测输入共模变化。一种替代的基于开关电容器的感测方案也是可能的。使用该测量的Vcmi，然后对采样器/转换器的其余部分进行调整，以取出在Vcmi处观察到的任何变化。

24. 发明授权

US06793668B1 Emboli capturing device 失效
标题翻译： Emboli拍摄装置
公开(公告)号：US06793668B1
公开(公告)日：2004-09-21
申请号：US10248418
申请日：2003-01-17
申请人： John S. Fisher
发明人： John S. Fisher
IPC分类号： A26M2900
CPC分类号： A61M25/104 , A61F2/013 , A61F2/958 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0078 , A61F2230/008 , A61M2025/0004
摘要： A balloon angioplasty or stenting apparatus includes a guide wire, a balloon catheter ensleeving the guide wire, and a guide catheter ensleeving the balloon catheter. The balloon catheter has slots formed in it to define elongate members between the slots. A joint is formed at the proximal, distal, and mid-point of each elongate member. Displacing the proximal and distal joints toward and away from one another causes the respective middle joints to displace radially outwardly and inwardly, respectively. A mesh that captures emboli while allowing blood perfusion partially overlies the jointed members is opened and closed when the jointed members are opened and closed. A guide wire having an outer coil and an inner rod slideably received within it has jointed members formed in the outer coil. The mesh is opened and closed by axially retracting and advancing the inner rod with respect to the outer coil, respectively.
摘要翻译：球囊血管成形术或支架置入装置包括引导线，包围引导线的气囊导管以及包围球囊导管的引导导管。气囊导管具有形成在其中的槽，以在槽之间限定细长构件。在每个细长构件的近端，远端和中点处形成接头。将近端和远端关节朝着彼此和远离的方向放置时，各个中间的关节分别径向向外和向内移位。当接合构件打开和关闭时，打开并关闭在允许血液灌注部分地覆盖接合构件的情况下捕获栓塞的网状物。具有外线圈和可滑动地容纳在其中的内杆的导丝具有形成在外线圈中的接合构件。通过分别相对于外部线圈轴向缩回和推进内杆来打开和关闭网状物。

25. 发明授权

US06685727B2 Bioabsorbable sealant 有权
标题翻译：生物可吸收密封剂
公开(公告)号：US06685727B2
公开(公告)日：2004-02-03
申请号：US10249261
申请日：2003-03-27
申请人： John S. Fisher , Frederick Ahari , Lucjan J. Hronowski
发明人： John S. Fisher , Frederick Ahari , Lucjan J. Hronowski
IPC分类号： A61B1708
CPC分类号： A61B17/0644 , A61B17/0057 , A61B17/064 , A61B2017/00004 , A61B2017/00575 , A61B2017/00601
摘要： Openings in a mammalian body made by any medical procedure or non-medical event are sealed with a bioabsorbable plug or sewn with a bioabsorbable suture. In one exemplary embodiment, the plug in dehydrated, unexpanded condition is pushed by a pushing device through the lumen of a needle until a first part of the plug is external to the opening and a second part is internal to the opening. The needle is then withdrawn while the position of the pushing device is maintained. The pushing device is then withdrawn, leaving the plug in sealing relation to the opening. The body's moisture causes the plug to expand to complete the sealing of the opening, or the expansion may be caused by exposure to air, light, or other stimulant. The opening may be formed in soft tissue, internal organs, or hard tissue. The plug seals the flow of liquid or gaseous biological fluids.
摘要翻译：通过任何医疗程序或非医疗事件制成的哺乳动物体内的开口用生物可吸收的塞子密封或用生物可吸收的缝线缝合。在一个示例性实施例中，脱水，未膨胀状态的塞子被推动装置推动穿过针管，直到插头的第一部分在开口外部，第二部分在开口内部。然后在保持推动装置的位置的同时取出针。然后将推动装置取出，使塞子与开口密封。身体的水分导致插头膨胀以完成开口的密封，或者膨胀可能由于暴露于空气，光线或其他兴奋剂而引起。开口可以形成在软组织，内部器官或硬组织中。塞子密封液体或气体生物流体的流动。

26. 发明申请

US20170066162A9 Method of Enhancing Ultrasound Visibility of Hyperechoic Materials 审中-公开
标题翻译：提高高回声材料超声可见度的方法
公开(公告)号：US20170066162A9
公开(公告)日：2017-03-09
申请号：US12022531
申请日：2008-01-30
申请人： John S. Fisher
发明人： John S. Fisher
IPC分类号： A61B8/00
CPC分类号： B29C39/10 , A61B90/39 , A61B2017/00004 , A61B2017/00526 , A61B2017/00898 , A61B2090/3925
摘要： A permanent or temporary marker is embedded within a hydrogel plug used in a biopsy procedure to indicate the location of a suspicious lesion so that the marker may be found in a subsequent surgical procedure. A combination of at least one permanent and at least one temporary marker may be used. Inserts of differing sizes and shapes may also be placed into the hydrogel plugs during their manufacturing process and removed from the plugs after the plugs have cured so that air-filled cavities are left in the plug. These cavities are temporary but may be used to augment location of a permanent marker.
摘要翻译：永久或临时标记物嵌入在活检程序中使用的水凝胶塞中以指示可疑病变的位置，使得可以在随后的手术过程中发现标记。可以使用至少一个永久和至少一个临时标记的组合。不同尺寸和形状的插入件也可以在其制造过程中被放置到水凝胶塞中，并且在塞子固化之后从塞子中移除，使得充满空气的孔留在塞子中。这些空腔是暂时的，但可用于增加永久性标记的位置。

27. 发明申请

US20080161848A1 Biodegradable polymer for making tissue and sealing tracts 有权
标题翻译：用于制作组织和密封条的可生物降解聚合物
公开(公告)号：US20080161848A1
公开(公告)日：2008-07-03
申请号：US11784310
申请日：2007-04-06
申请人： John S. Fisher
发明人： John S. Fisher
IPC分类号： A61B17/03
CPC分类号： A61L24/0042 , A61B90/39 , A61B2017/00004 , A61B2017/00893 , A61B2017/00898 , A61L24/0015 , A61L24/0031 , A61L31/18 , A61L2300/406 , A61L2300/41 , A61L2300/416 , A61L2300/44 , A61L2300/604
摘要： A tissue marker formed of a biodegradable polymer having drug-delivery capabilities is combined with a sealant that encapsulates the tissue marker and which serves to help anchor the tissue marker against migration. The sealant is delivered to a site in dehydrated form and moisture inherent in tissue at the site expands the sealant. The expanded sealant is formed of a hydrogel and is therefore more compatible to the surrounding tissue than the material of the tissue marker. The sealant and the tissue marker are both bioabsorbed over time.
摘要翻译：由具有药物递送能力的可生物降解的聚合物形成的组织标记物与封装组织标记物的密封剂组合，并且其用于帮助锚定组织标记物抵抗迁移。密封剂被递送到脱水形式的部位，并且在该部位组织中固有的水分使密封剂膨胀。膨胀的密封剂由水凝胶形成，因此与组织标记的材料相比，与周围组织更相容。密封剂和组织标记物随时间生物吸收。

28. 发明授权

US07329414B2 Biodegradable polymer for marking tissue and sealing tracts 有权
标题翻译：用于标记组织和密封带的生物可降解聚合物
公开(公告)号：US07329414B2
公开(公告)日：2008-02-12
申请号：US10063620
申请日：2002-05-03
申请人： John S. Fisher , Frederick Ahari , Lucjan J. J. Hronowski
发明人： John S. Fisher , Frederick Ahari , Lucjan J. J. Hronowski
IPC分类号： A61F2/02 , A61K51/02
CPC分类号： A61L24/0042 , A61B90/39 , A61B2017/00004 , A61B2017/00893 , A61B2017/00898 , A61L24/0015 , A61L24/0031 , A61L31/18 , A61L2300/406 , A61L2300/41 , A61L2300/416 , A61L2300/44 , A61L2300/604
摘要： A tissue marker formed of a biodegradable polymer having drug-delivery capabilities is combined with a sealant that encapsulates the tissue marker and which serves to help anchor the tissue marker against migration. The sealant is delivered to a site in dehydrated form and moisture inherent in tissue at the site expands the sealant. The expanded sealant is formed of a hydrogel and is therefore more compatible to the surrounding tissue than the material of the tissue marker. The sealant and the tissue marker are both bioabsorbed over time.
摘要翻译：由具有药物递送能力的可生物降解的聚合物形成的组织标记物与封装组织标记物的密封剂组合，并且其用于帮助锚定组织标记物抵抗迁移。密封剂被递送到脱水形式的部位，并且在该部位组织中固有的水分使密封剂膨胀。膨胀的密封剂由水凝胶形成，因此与组织标记的材料相比，与周围组织更相容。密封剂和组织标记物随时间生物吸收。

29. 发明授权

US07001410B2 Bioabsorbable sealant 有权
公开(公告)号：US07001410B2
公开(公告)日：2006-02-21
申请号：US10249263
申请日：2003-03-27
申请人： John S. Fisher , Frederick Ahari , Lucjan J. J. Hronowski
发明人： John S. Fisher , Frederick Ahari , Lucjan J. J. Hronowski
IPC分类号： A61B17/04
CPC分类号： A61B17/0644 , A61B17/0057 , A61B17/064 , A61B2017/00004 , A61B2017/00575 , A61B2017/00601
摘要： Openings in a mammalian body made by any medical procedure or non-medical event are sealed with a bioabsorbable plug or sewn with a bioabsorbable suture. In one exemplary embodiment, the plug in dehydrated, unexpanded condition is pushed by a pushing device through the lumen of a needle until a first part of the plug is external to the opening and a second part is internal to the opening. The needle is then withdrawn while the position of the pushing device is maintained. The pushing device is then withdrawn, leaving the plug in sealing relation to the opening. The body's moisture causes the plug to expand to complete the sealing of the opening, or the expansion may be caused by exposure to air, light, or other stimulant. The opening may be formed in soft tissue, internal organs, or hard tissue. The plug seals the flow of liquid or gaseous biological fluids.

30. 发明授权

US06994712B1 Bioabsorbable marker having external anchoring means 有权
标题翻译：具有外部锚定装置的生物可吸收标记物
公开(公告)号：US06994712B1
公开(公告)日：2006-02-07
申请号：US10065704
申请日：2002-11-12
申请人： John S. Fisher , Frederick Ahari
发明人： John S. Fisher , Frederick Ahari
IPC分类号： A61B19/00
CPC分类号： A61B90/39 , A61B2017/00004 , A61B2090/3908 , A61B2090/3987
摘要： A clip and a bioabsorbable marker are employed to mark a biopsy site. The former provides a permanent marker that is clamped onto tissue and that cannot migrate from the site over time. The latter is gradually bioabsorbed over time but the time may vary widely from weeks to months. In most embodiments, the clip and marker are integrally formed with one another at the time of manufacture. In one embodiment, the clip and marker are independently made but are joined to one another during the site-marking process. The markers are deployed by core biopsy needles of the type employing a vacuum, of the type that does not employ a vacuum, and by coaxial biopsy needles.
摘要翻译：使用夹子和生物可吸收标记来标记活检部位。前者提供了一个永久标记，夹在组织上，不能随时间从现场迁移。后者随着时间的推移逐渐生物吸收，但时间可能会在几周到几个月不等。在大多数实施例中，夹子和标记在制造时彼此一体形成。在一个实施例中，夹子和标记器是独立制造的，但在位置标记过程期间彼此连接。标记物由使用不使用真空的类型的真空的类型的核心活检针和同轴活检针部署。

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