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21. 发明申请

US20080286315A1 Methionine Enkephalin as an Adjuvant for Vaccine Immunizations 审中-公开
标题翻译：甲硫氨酸脑啡肽作为疫苗免疫的佐剂
公开(公告)号：US20080286315A1
公开(公告)日：2008-11-20
申请号：US12022854
申请日：2008-01-30
申请人： John Huang , Ding Chang , Shi-lung Lo , Feng Ping Shan
发明人： John Huang , Ding Chang , Shi-lung Lo , Feng Ping Shan
IPC分类号： A61K39/00 , A61K35/12 , A61P37/00 , C12N5/06
CPC分类号： C12N5/0639 , A61K38/33 , A61K39/0011 , A61K2039/5154 , A61K2039/55516 , C12N2501/22 , C12N2501/23 , C12N2501/85 , A61K2300/00
摘要： The present invention provides a method of stimulating dendritic cells, comprising contacting the dendritic cells with methionine enkephalin. The present invention also provides methods of enhancing an immune response to an antigen in a mammal. In a first method, dendritic cells are isolated from the mammal. The dendritic cells are then contacted with methionine enkephalin for a time sufficient to stimulate the cells. Next, the stimulated dendritic cells are contacted with the antigen of interest for a time sufficient for the cells to process the antigen. The dendritic cells are then injected into the mammal. The dendritic cells may be injected into the animal either on their own, or along with methionine enkephalin and/or the antigen. In a second method, the antigen of interest and methionine enkephalin are administered to the mammal. The present invention also provides compositions for administration to a mammalian subject having a tumor.
摘要翻译：本发明提供了一种刺激树突状细胞的方法，包括使树状细胞与甲硫氨酸脑啡肽接触。本发明还提供增强对哺乳动物中的抗原的免疫应答的方法。在第一种方法中，从哺乳动物中分离树突状细胞。然后将树突状细胞与甲硫氨酸脑啡肽接触足以刺激细胞的时间。接下来，刺激的树突状细胞与感兴趣的抗原接触足以使细胞处理抗原的时间。然后将树突状细胞注射到哺乳动物中。树突细胞可以自己注射入动物，或与甲硫氨酸脑啡肽和/或抗原一起注射到动物体内。在第二种方法中，向哺乳动物施用目的抗原和甲硫氨酸脑啡肽。本发明还提供了用于给予具有肿瘤的哺乳动物受试者的组合物。

22. 发明授权

US6081234A Beam scanning reflectarray antenna with circular polarization 失效
标题翻译：光束扫描反射阵列天线圆极化
公开(公告)号：US6081234A
公开(公告)日：2000-06-27
申请号：US891631
申请日：1997-07-11
申请人： John Huang , Ronald J. Pogorzelski
发明人： John Huang , Ronald J. Pogorzelski
IPC分类号： H01Q3/14 , H01Q3/46 , H01Q19/06
CPC分类号： H01Q3/14 , H01Q19/06 , H01Q3/46
摘要： A novel means of scanning a circularly polarized reflectarray antenna. The reflectarray is an array of metallic elements arranged on a surface designed to compensate for the various path lengths of the optical rays from an illuminating feed to the reflecting surface and then to the antenna aperture. With appropriate design, the phase in the aperture can be made to vary linearly in any desired direction and also to produce a radiated beam normal to the constant phase surface. In the case of circular polarization, this path length compensation can be accomplished by rotation of the individual elements.
摘要翻译：扫描圆偏振反射阵列天线的新颖手段。反射阵列是布置在表面上的金属元件阵列，设计成用于补偿从照明馈送到反射表面然后到天线孔径的光线的各种路径长度。通过适当的设计，可以使孔径中的相位在任何所需方向上线性变化，并且还产生垂直于恒定相面的辐射光束。在圆极化的情况下，可以通过各个元件的旋转来实现该路径长度补偿。

23. 发明授权

US5220335A Planar microstrip Yagi antenna array 失效
标题翻译：平板微带八木天线阵列
公开(公告)号：US5220335A
公开(公告)日：1993-06-15
申请号：US664445
申请日：1991-02-28
申请人： John Huang
发明人： John Huang
IPC分类号： H01Q1/38 , H01Q19/30
CPC分类号： H01Q19/30 , H01Q1/38
摘要： A directional microstrip antenna includes a driven patch surrounded by an isolated reflector and one or more coplanar directors, all separated from a groundplane on the order of 0.1 wavelength or less to provide endfire beam directivity without requiring power dividers or phase shifters. The antenna may be driven at a feed point a distance from the center of the driven patch in accordance with conventional microstrip antenna design practices for H-plane coupled or horizontally polarized signals. The feed point for E-plane coupled or vertically polarized signals is at a greater distance from the center than the first distance. This feed point is also used for one of the feed signals for circularly polarized signals. The phase shift between signals applied to feed points for circularly polarized signals must be greater than the conventionally required 90.degree. and depends upon the antenna configuration.
摘要翻译：定向微带天线包括由隔离的反射器和一个或多个共面导向器包围的驱动补片，所有导体都与0.1波长或更小的接地面分开，以提供端射射束方向性，而不需要功率分配器或移相器。根据用于H平面耦合或水平极化信号的常规微带天线设计实践，天线可以在距驱动贴片中心一个距离的馈电点处被驱动。 E平面耦合或垂直极化信号的馈电点距离中心比第一距离更大。该馈电点也用于圆偏振信号的馈送信号之一。施加到圆偏振信号的馈电点的信号之间的相移必须大于常规要求的90°，并且取决于天线配置。

24. 发明授权

US09037983B1 User privilege based web page content editing 有权
标题翻译：基于用户权限的网页内容编辑
公开(公告)号：US09037983B1
公开(公告)日：2015-05-19
申请号：US11638857
申请日：2006-12-13
申请人： Igor Shmulevich , John Huang , Andy Simmons , Gary Tang
发明人： Igor Shmulevich , John Huang , Andy Simmons , Gary Tang
IPC分类号： G06F3/00 , G06F3/048
CPC分类号： G06F3/00 , G06F3/048 , G06F17/22 , G06F17/2288 , G06F17/24 , G06F21/60
摘要： Selectively restricting changes to a web page is disclosed. It is determined whether a current user is to be limited to editing content. If it is determined that the current user is to be limited to editing content, an interface that enables the current user to edit a content data but not an associated layout data of the web page is displayed to the user, based at least in part on the determination.
摘要翻译：公开了对网页的选择性限制。确定当前用户是否被限制为编辑内容。如果确定当前用户被限制为编辑内容，则至少部分地基于用户向用户显示使当前用户能够编辑内容数据而不是相关联的布局数据的界面决心。

25. 发明授权

US08492334B2 Sustained intraocular delivery of drugs from biodegradable polymeric microparticles 有权
标题翻译：从可生物降解的聚合物微粒中持续的眼内输送药物
公开(公告)号：US08492334B2
公开(公告)日：2013-07-23
申请号：US12664792
申请日：2008-06-18
申请人： Erin Lavik , Young H. Kwon , Markus Kuehn , Sandeep Saluja , James Bertram , John Huang
发明人： Erin Lavik , Young H. Kwon , Markus Kuehn , Sandeep Saluja , James Bertram , John Huang
IPC分类号： A61K38/18 , A61K38/22 , A61K31/7036 , A61K31/704 , A61K31/57 , A61K31/573
CPC分类号： A61K9/1647 , A61K9/0048 , A61K9/5153
摘要： Biodegradable polymeric microparticle compositions containing one or more active agents, especially those useful for treating or preventing one or more diseases or disorders of the eye, and methods of making and using thereof, are described. In a preferred embodiment, the microparticle compositions contain one or more active agents useful for managing elevated intraocular pressure (IOP) in the eye. Relatively hydrophilic, and preferably carboxylated, polymeric materials such as PLGA are used for a drug such as timolol maleate, which is relatively water soluble, to increase drug loading. Higher molecular weight polymers, as well as the ratio of LA (which has a longer degradation time, up to one to two years) to GA (which has a short degradation time, as short as a few days to a week), are used to provide release over a longer period of time.
摘要翻译：描述了包含一种或多种活性剂，特别是可用于治疗或预防一种或多种眼睛疾病或病症的活性剂的生物降解性聚合物微粒组合物及其制备和使用方法。在优选的实施方案中，微粒组合物含有一种或多种用于治疗眼中升高的眼内压（IOP）的活性剂。相对亲水的，优选羧化的聚合物材料如PLGA用于药物，例如相对水溶性的马来酸噻吗洛尔，以增加药物负荷。使用较高分子量的聚合物，以及LA（其具有较长的降解时间，长达一至两年）与GA（其具有短的降解时间，短至几天至一周）的比率被使用提供更长时间的释放。

26. 发明授权

US08228957B1 Differential delay mitigation in diverse backhaul environments 有权
标题翻译：不同回程环境中的差分延迟缓解
公开(公告)号：US08228957B1
公开(公告)日：2012-07-24
申请号：US11442460
申请日：2006-05-26
申请人： Boris Rabinovich , John Huang
发明人： Boris Rabinovich , John Huang
IPC分类号： H04J3/06
CPC分类号： H04W56/005 , H04L47/283
摘要： A communication system comprises a mobile switching center configured to determine a first delay metric for first traffic on a first path from the mobile switching center to a first node, and determine a first delay differential based on the first delay metric and a second delay metric for second traffic on a second path from the mobile switching center to a second node. The communication system also comprises the second node having a delay buffer configured to delay the second traffic based on the first delay differential.
摘要翻译：一种通信系统包括：移动交换中心，被配置为确定从所述移动交换中心到第一节点的第一路径上的第一业务的第一延迟度量，以及基于所述第一延迟度量和第二延迟度量确定第一延迟差分，在从移动交换中心到第二节点的第二路径上的第二业务。通信系统还包括具有延迟缓冲器的第二节点，该延迟缓冲器被配置为基于第一延迟差异来延迟第二业务。

27. 发明申请

US20110161289A1 Data Replication Across Enterprise Boundaries 有权
标题翻译：跨企业边界的数据复制
公开(公告)号：US20110161289A1
公开(公告)日：2011-06-30
申请号：US12649829
申请日：2009-12-30
申请人： Mingliang Pei , Oanh Hoang , Ruiping Sun , John Huang
发明人： Mingliang Pei , Oanh Hoang , Ruiping Sun , John Huang
IPC分类号： G06F17/30 , G06F21/00
CPC分类号： G06F17/30581
摘要： Systems and methods for synchronizing verification data in a distributed database including client and server databases. The server database may exchange verification data regarding one-time passwords to multiple client databases. An update to the server database may be initiated based on information stored in the client database by pushing updated verification information from the client database to the server database via an SSL tunnel. An update to the client database may be initiated based on information stored in the server database by pulling updated verification data from the server database to the client database via an SSL tunnel. The client database and the server database may include a two-dimensional data field including the verification data and an associated key identifier, and a site ID. The site ID may include a unique identifier to identify the respective database in which it is included. The data field may include a sequence number assigned to each row of data that increases every time the row of information is updated. The client database and the server database may also include a replication tracking table including a record of the last known update to a remote database. Data fields that require updating may be determined based on the site ID and a comparison of the sequence numbers from the replication tracking table and the server's database.
摘要翻译：用于在包括客户端和服务器数据库的分布式数据库中同步验证数据的系统和方法。服务器数据库可以将关于一次性密码的验证数据交换到多个客户数据库。可以基于通过SSL隧道将更新的验证信息从客户端数据库推送到服务器数据库，基于存储在客户端数据库中的信息来启动对服务器数据库的更新。可以基于存储在服务器数据库中的信息，通过经由SSL隧道将更新的验证数据从服务器数据库拉到客户端数据库来启动对客户端数据库的更新。客户端数据库和服务器数据库可以包括包括验证数据和相关联的密钥标识符的二维数据字段以及站点ID。站点ID可以包括用于标识其中包括其的相应数据库的唯一标识符。数据字段可以包括分配给每次更新信息行时每增加一行数据的序列号。客户端数据库和服务器数据库还可以包括复制跟踪表，其包括对远程数据库的最后已知更新的记录。需要更新的数据字段可以基于站点ID和来自复制跟踪表和服务器数据库的序列号的比较来确定。

28. 发明授权

US07686472B1 Self-defense flashlight with protectable sharp edges 失效
标题翻译：防护手电筒具有可保护的锋利边缘
公开(公告)号：US07686472B1
公开(公告)日：2010-03-30
申请号：US12022102
申请日：2008-01-29
申请人： John Huang
发明人： John Huang
IPC分类号： F21L4/00
CPC分类号： F21L4/005 , F21V15/01 , F21V33/0076 , F41B15/00 , F41B15/08
摘要： A self-defense flashlight includes sharp edges positioned around the head end. A sharp edge protector can be positioned so as to surround and protect the sharp edges, when the flashlight is not being used for self-defense purposes. When needed, the sharp edge protector can be moved so as to expose the sharp edges, allowing the flashlight to be used as a weapon. The protectable sharp edges can also be positioned around the tail end of the self-defense flashlight.
摘要翻译：自拍手电筒包括围绕头端定位的锋利边缘。当手电筒不被用于自卫目的时，锋利的边缘保护器可以被定位成围绕和保护锋利的边缘。当需要时，锋利的边缘保护器可以被移动以暴露锋利的边缘，从而使手电筒被用作武器。可保护的锋利边缘也可以围绕自卫手电筒的尾端定位。

29. 发明授权

US06781561B2 Antenna for a tire pressure detector 失效
标题翻译：轮胎压力检测器天线
公开(公告)号：US06781561B2
公开(公告)日：2004-08-24
申请号：US10384971
申请日：2003-03-10
申请人： John Huang , Chi-Hui Chuang
发明人： John Huang , Chi-Hui Chuang
IPC分类号： H01Q136
CPC分类号： H01Q1/36 , H01Q1/3208
摘要： An antenna for a tire pressure detector is installed on an RF circuit board of the tire pressure detector. The antenna has a seat with a bottom plate. A post is uprightly formed on the bottom plate. A plurality of positioning members evenly formed at an outer periphery of the post. A wire electrically connected with the RF circuit board is coiled round the post and positioned in the positioning members. A cover has a body provided outside the seat. A bolt is inserted through the cover to fasten the antenna on the RF circuit board. The antenna has a low manufacturing cost, and is convenient to be installed.
摘要翻译：用于轮胎压力检测器的天线安装在轮胎压力检测器的RF电路板上。天线具有带底板的座。立柱上形成立柱。多个定位构件均匀地形成在柱的外周。与RF电路板电连接的导线绕在柱上并定位在定位构件中。盖子具有设置在座椅外部的主体。一个螺栓穿过盖子，将天线固定在RF电路板上。天线制造成本低，安装方便。

30. 发明授权

US5422649A Parallel and series FED microstrip array with high efficiency and low cross polarization 失效
标题翻译：并联和串联FED微带阵列，具有高效率和低交叉极化
公开(公告)号：US5422649A
公开(公告)日：1995-06-06
申请号：US304641
申请日：1994-09-09
申请人： John Huang
发明人： John Huang
IPC分类号： H01Q21/00 , H01Q21/06 , H01Q1/38
CPC分类号： H01Q21/0075 , H01Q21/065
摘要： A microstrip array antenna for vertically polarized fan beam (approximately 2.degree..times.50.degree.) for C-band SAR applications with a physical area of 1.7 m by 0.17 m comprises two rows of patch elements and employs a parallel feed to left- and right-half sections of the rows. Each section is divided into two segments that are fed in parallel with the elements in each segment fed in series through matched transmission lines for high efficiency. The inboard section has half the number of patch elements of the outboard section, and the outboard sections, which have tapered distribution with identical transmission line sections, terminated with half wavelength long open-circuit stubs so that the remaining energy is reflected and radiated in phase. The elements of the two inboard segments of the two left- and right-half sections are provided with tapered transmission lines from element to element for uniform power distribution over the central third of the entire array antenna. The two rows of array elements are excited at opposite patch feed locations with opposite (180.degree. difference) phases for reduced cross-polarization.
摘要翻译：用于物理面积为1.7米×0.17米的C波段SAR应用的垂直极化扇形光束（约2度×50度）的微带阵列天线包括两排贴片元件，并采用平行馈电到左右两侧行的部分。每个部分被分成两个段，每个段与通过匹配的传输线串联馈送的每个段中的元件并联馈送，以实现高效率。内侧部分具有外侧部分的补片元件的数量的一半，并且具有相同传输线部分的锥形分布的外侧部分以半波长长的开路短截线终止，使得剩余能量被反射和相位辐射。两个左右两部分的两个内侧段的元件设置有从元件到元件的锥形传输线，用于在整个阵列天线的中心三分之一上均匀分配功率。两行阵列元件在具有相反（180°差）相位的相对的贴片馈电位置被激发，以减少交叉极化。

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