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21. 发明申请

US20070089201A1 Plant production of immunoglobulins with reduced fucosylation 有权
标题翻译：减少岩藻糖基化的免疫球蛋白的植物生产
公开(公告)号：US20070089201A1
公开(公告)日：2007-04-19
申请号：US10536875
申请日：2003-11-28
申请人： Kristen Briggs , Todd Glancy , Mich Hein , Andrew Hiatt , Anton Karnoup , W. H. Anderson , Dayakar Pareddy , Joseph Petolino , Beth Rubin-Wilson , Doug Taylor , Jean Roberts
发明人： Kristen Briggs , Todd Glancy , Mich Hein , Andrew Hiatt , Anton Karnoup , W. H. Anderson , Dayakar Pareddy , Joseph Petolino , Beth Rubin-Wilson , Doug Taylor , Jean Roberts
IPC分类号： A01H5/00 , C07K16/18 , C12N5/04 , C12N15/82
CPC分类号： C12N15/8258 , A61K2039/505 , C07K16/00 , C07K16/087 , C07K16/2839 , C07K2317/13 , C07K2317/41
摘要： This invention provides for the plant production of immunoglobulins, wherein at least a portion of the glycans attached to the immunoglobulins lack fucose. The invention also provides the constructs; plasmids; vectors; transformed plant cells, transformed plant calli; transformed plant tissues (e.g., leaves, seeds, tubers, etc.); transformed whole plants used to produce such immunoglobulins; methods of producing the immunoglobulins; the immunoglobulins produced by the disclosed methods; and the use of such immunoglobulins.
摘要翻译：本发明提供免疫球蛋白的植物生产，其中与免疫球蛋白连接的至少一部分聚糖缺乏岩藻糖。本发明还提供了构建体; 质粒向量转化植物细胞，转化植物愈伤组织; 转化的植物组织（例如叶，种子，块茎等）; 转化用于产生这种免疫球蛋白的整个植物; 生产免疫球蛋白的方法; 通过公开的方法产生的免疫球蛋白; 以及使用这种免疫球蛋白。

22. 发明申请

US20060035014A1 Method of coating microelectronic substrates 失效
公开(公告)号：US20060035014A1
公开(公告)日：2006-02-16
申请号：US11261299
申请日：2005-10-28
申请人： James DeYoung , James McClain , Stephen Gross , Doug Taylor , Mark Wagner , David Brainard
发明人： James DeYoung , James McClain , Stephen Gross , Doug Taylor , Mark Wagner , David Brainard
IPC分类号： B05D5/12
CPC分类号： H01L21/283 , B05D1/18 , B05D2401/90 , H01L21/28556 , H01L21/288 , H01L21/67028 , H01L28/65
摘要： A method of coating a substrate comprises the steps of: (a) providing a substrate in an enclosed vessel, the substrate having a surface portion; (b) at least partially filling the enclosed vessel with a first supercritical fluid so that said first supercritical fluid contacts the surface portion, with the first supercritical fluid carrying or containing a coating component; then (c) adding a separate compressed gas atmosphere to the reaction vessel so that a boundary is formed between the first supercritical fluid and the separate compressed gas atmosphere, said separate compressed gas atmosphere having a density less than said first supercritical fluid; and then (d) displacing said first supercritical fluid from said vessel by continuing adding said separate compressed gas atmosphere to said vessel so that said boundary moves across said surface portion and a thin film of coating component is deposited on said microelectronic substrate.

23. 发明授权

US08852625B2 Coatings containing multiple drugs 有权
标题翻译：含多种药物的涂料
公开(公告)号：US08852625B2
公开(公告)日：2014-10-07
申请号：US12298459
申请日：2007-04-26
申请人： James DeYoung , Doug Taylor , Jim McClain , Clint Smoke , Mike Cole
发明人： James DeYoung , Doug Taylor , Jim McClain , Clint Smoke , Mike Cole
IPC分类号： A61L31/10 , A61L31/16
CPC分类号： A61L31/16 , A61F2/90 , A61F2210/0004 , A61F2250/0067 , A61L31/06 , A61L31/10 , A61L31/148 , A61L2300/20 , A61L2300/216 , A61L2300/236 , A61L2300/416 , A61L2300/42 , A61L2300/426 , A61L2300/602 , A61L2300/608 , A61L2300/61 , A61L2420/02 , A61L2420/06 , A61L2420/08
摘要： A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.
摘要翻译：一种用于在基底上沉积包含聚合物和至少两种药剂的涂层的方法，包括以下步骤：提供支架框架; 在所述支架框架上沉积包含第一药剂的第一层; 沉积包含第二药剂的第二层; 其中所述第一和第二药剂选自两种不同类型的药剂。

24. 发明授权

US08758429B2 Polymer coatings containing drug powder of controlled morphology 有权
标题翻译：含有受控形态药物粉末的聚合物涂层
公开(公告)号：US08758429B2
公开(公告)日：2014-06-24
申请号：US13605904
申请日：2012-09-06
申请人： Doug Taylor , Jim McClain , Clint Smoke , Mike Cole , James DeYoung
发明人： Doug Taylor , Jim McClain , Clint Smoke , Mike Cole , James DeYoung
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2210/0076 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/426 , A61L2300/606 , A61L2300/63 , A61L2420/08 , Y10T428/264 , Y10T428/265 , Y10T428/31507 , Y10T428/31544 , Y10T428/31551 , Y10T428/31663 , Y10T428/31786 , Y10T428/31935 , Y10T428/31938
摘要： A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.
摘要翻译：一种用于在基底上沉积包含聚合物和药剂的涂层的方法，包括以下步骤：通过第一孔排出至少一种治疗上需要的干粉形式的药剂; 通过第二孔排出至少一种干粉形式的聚合物; 将所述聚合物和/或药物颗粒沉积到所述基底上，其中在所述基底和所述药物和/或聚合物颗粒之间保持电位，从而形成所述涂层; 并且在不显着改变所述药剂的形态的条件下烧结所述涂层。

25. 发明申请

US20130109270A1 Expander and Action Figure with an Expander 审中-公开
标题翻译：扩展器和动作图与扩展器
公开(公告)号：US20130109270A1
公开(公告)日：2013-05-02
申请号：US13347419
申请日：2012-01-10
申请人： Ruben Martinez , Steed Sun , Doug Taylor
发明人： Ruben Martinez , Steed Sun , Doug Taylor
IPC分类号： A63H13/00 , A63H33/00
CPC分类号： A63H13/00 , A63H33/00 , A63H33/003
摘要： An expander has a collapsed configuration and a deployed configuration. The expander has at least one expander component that is movably coupled to another expander component. The expander may be used with a toy figure. In one implementation, each of the expander components is pivotally coupled to another expander component. The expander includes a biasing member that biases adjacent expander components away from each other.
摘要翻译：扩展器具有折叠配置和部署配置。膨胀器具有至少一个可移动地耦合到另一膨胀器部件的膨胀器部件。扩展器可以与玩具人物一起使用。在一个实施方案中，每个膨胀器部件枢转地联接到另一个膨胀器部件。膨胀机包括偏置构件，该偏置构件使相邻的膨胀器组件偏离彼此。

26. 发明授权

US08106169B2 Plant production of immunoglobulins with reduced fucosylation 有权
标题翻译：减少岩藻糖基化的免疫球蛋白的植物生产
公开(公告)号：US08106169B2
公开(公告)日：2012-01-31
申请号：US10536875
申请日：2003-11-28
申请人： Kristen Briggs , Todd Glancy , Mich B. Hein , Andrew C. Hiatt , Anton S. Karnoup , W. H. Kerr Anderson , Dayakar Pareddy , Joseph Petolino , Beth Rubin-Wilson , Doug Taylor , Jean L. Roberts
发明人： Kristen Briggs , Todd Glancy , Mich B. Hein , Andrew C. Hiatt , Anton S. Karnoup , W. H. Kerr Anderson , Dayakar Pareddy , Joseph Petolino , Beth Rubin-Wilson , Doug Taylor , Jean L. Roberts
IPC分类号： C07K16/08 , C07K16/00 , C12N15/82
CPC分类号： C12N15/8258 , A61K2039/505 , C07K16/00 , C07K16/087 , C07K16/2839 , C07K2317/13 , C07K2317/41
摘要： This invention provides for the plant production of immunoglobulins, wherein at least a portion of the glycans attached to the immunoglobulins lack fucose. The invention also provides the constructs; plasmids; vectors; transformed plant cells, transformed plant calli; transformed plant tissues (e.g., leaves, seeds, tubers, etc.); transformed whole plants used to produce such immunoglobulins; methods of producing the immunoglobulins; the immunoglobulins produced by the disclosed methods; and the use of such immunoglobulins.
摘要翻译：本发明提供免疫球蛋白的植物生产，其中与免疫球蛋白连接的至少一部分聚糖缺乏岩藻糖。本发明还提供了构建体; 质粒向量转化的植物细胞，转化植物愈伤组织; 转化的植物组织（例如叶，种子，块茎等）; 转化用于产生这种免疫球蛋白的整个植物; 生产免疫球蛋白的方法; 通过公开的方法产生的免疫球蛋白; 以及使用这种免疫球蛋白。

27. 发明授权

US07592035B2 Method of coating microelectronic substrates 失效
标题翻译：涂布微电子基板的方法
公开(公告)号：US07592035B2
公开(公告)日：2009-09-22
申请号：US11261299
申请日：2005-10-28
申请人： James P. DeYoung , James B. McClain , Stephen M. Gross , Doug Taylor , Mark I. Wagner , David Brainard
发明人： James P. DeYoung , James B. McClain , Stephen M. Gross , Doug Taylor , Mark I. Wagner , David Brainard
IPC分类号： B05D5/12
CPC分类号： H01L21/283 , B05D1/18 , B05D2401/90 , H01L21/28556 , H01L21/288 , H01L21/67028 , H01L28/65
摘要： A method of coating a substrate comprises the steps of: (a) providing a substrate in an enclosed vessel, the substrate having a surface portion; (b) at least partially filling the enclosed vessel with a first supercritical fluid so that said first supercritical fluid contacts the surface portion, with the first supercritical fluid carrying or containing a coating component; then (c) adding a separate compressed gas atmosphere to the reaction vessel so that a boundary is formed between the first supercritical fluid and the separate compressed gas atmosphere, said separate compressed gas atmosphere having a density less than said first supercritical fluid; and then (d) displacing said first supercritical fluid from said vessel by continuing adding said separate compressed gas atmosphere to said vessel so that said boundary moves across said surface portion and a thin film of coating component is deposited on said microelectronic substrate.
摘要翻译：涂覆基材的方法包括以下步骤：（a）在封闭容器中提供基材，所述基材具有表面部分; （b）用第一超临界流体至少部分地填充封闭的容器，使得所述第一超临界流体接触表面部分，第一超临界流体携带或包含涂层组分; 然后（c）向所述反应容器中加入单独的压缩气体气氛，使得在所述第一超临界流体和所述单独的压缩气体气氛之间形成边界，所述单独的压缩气体气氛的密度小于所述第一超临界流体; 然后（d）通过将所述单独的压缩气体气氛继续加入到所述容器中，使所述边界移动穿过所述表面部分并且将涂层组分的薄膜沉积在所述微电子衬底上，从而使所述第一超临界流体从所述容器移位。

28. 发明申请

US20070151660A1 Process for manufacturing RFID label 审中-公开
标题翻译：制造RFID标签的过程
公开(公告)号：US20070151660A1
公开(公告)日：2007-07-05
申请号：US11318366
申请日：2005-12-23
申请人： Matt Adams , Otto Argadine , Doug Taylor , Kevin Conwell , Rick O'Brien , Jim Peternel
发明人： Matt Adams , Otto Argadine , Doug Taylor , Kevin Conwell , Rick O'Brien , Jim Peternel
IPC分类号： B65C9/18 , G08B13/14
CPC分类号： G06K19/07749 , B31D1/025 , G06K19/07718 , G06K19/0776
摘要： An automated process for manufacturing smart labels having a radio frequency identification transponder (RFID) transponder. The inventive method accurately and reliably inserts RFID transponders into labels on onto tags 70 in one pass on a label press 100 equipped with an in-line insertion station 120. The transponders may be provided in continuous supply reel and singulated as needed to form discrete terms transponders or single transponders may be provided in the hopper. The label is delaminated and the transponders are individually applied directly to the adhesive side of the labels in the machine direction of the moving web. The label liner is then relaminated back onto the label face stock sandwiching the RFID transponder between the liner and the label stock.
摘要翻译：一种用于制造具有射频识别应答器（RFID）应答器的智能标签的自动化过程。本发明的方法在装备有在线插入站120的标签印刷机100上一次通过时将RFID应答器精确可靠地插入到标签70上的标签中。应答器可以设置在连续的供应卷轴中并根据需要被分割以形成离散项应答器或单个转发器可以设置在料斗中。标签被分层，并且应答器被分别直接地贴在标签的粘合剂侧面上，在移动网的机器方向上。然后将标签衬垫重新贴到标签面上，夹在RFID标签上的RFID应答器之间。

29. 发明申请

US20060277001A1 Systems and methods for isolating local performance variation in website monitoring 有权
公开(公告)号：US20060277001A1
公开(公告)日：2006-12-07
申请号：US11142890
申请日：2005-06-01
申请人： Timothy Drees , Lenny Rachitsky , Doug Taylor
发明人： Timothy Drees , Lenny Rachitsky , Doug Taylor
IPC分类号： G06F11/00 , G06F15/00
CPC分类号： G06F11/3495 , G06F11/3409 , G06F2201/865 , G06F2201/875 , G06F2201/88
摘要： Systems and methods are provided for isolating performance variation in website monitoring. A set of geographically diverse monitoring agents are identified and a subset of baseline agents is selected from these monitoring agents. The baseline agents are those agents that are geographically close to the target website or otherwise enjoy reliable communications with the target website and are therefore less affected by network latencies. The frequency at which a target website is monitored is weighted in favor of the baseline agents in order to get an accurate baseline metric for the target website while also obtaining information regarding global accessibility of the website from the geographically disperse monitoring agents. The variations in sample frequency can be optimized for each particular set of baseline agents. The set of baseline agents can be pre-assigned or dynamically identified based on an analysis of the performance variation from each of the monitoring agents.

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