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21. 发明授权

US6019607A Method and apparatus for training of sensory and perceptual systems in LLI systems 失效
标题翻译：用于训练LLI科目感觉和感知系统的方法和装置
公开(公告)号：US6019607A
公开(公告)日：2000-02-01
申请号：US992071
申请日：1997-12-17
申请人： William M. Jenkins , Michael M. Merzenich , Steven Lamont Miller , Bret E. Peterson , Paula Tallal
发明人： William M. Jenkins , Michael M. Merzenich , Steven Lamont Miller , Bret E. Peterson , Paula Tallal
IPC分类号： G06K9/00
CPC分类号： G09B19/04
摘要： An apparatus and method for training the sensory perceptual system in a language learning impaired (LLI) subject is provided. The apparatus and method incorporates a number of different programs to be played by the subject. The programs artificially process selected portions of language elements, called phonemes, so they will be more easily distinguished by an LLI subject, and gradually improves the subject's neurological processing of the elements through repetitive stimulation. The programs continually monitor a subject's ability to distinguish the processed language elements, and adaptively configures the programs to challenge and reward the subject by altering the degree of processing. Through adaptive control and repetition of processed speech elements, and presentation of the speech elements in a creative fashion, a subject's temporal processing of acoustic events common to speech are significantly improved.
摘要翻译：提供了一种用于训练语言学习障碍（LLI）受试者的感觉知觉系统的装置和方法。该装置和方法包含若干不同程序要被主体播放。程序人为处理语言元素的所选部分，称为音素，因此它们将被LLI主体更容易区分，并且通过重复刺激逐渐改善受试者对元件的神经学处理。程序不断监视被摄体区分已处理语言元素的能力，并通过改变处理程度自适应地配置程序来挑战和奖励主题。通过自适应控制和处理的语音元素的重复以及以创造性的方式呈现语音元素，对话语的共同声学事件的对象的时间处理被显着改善。

22. 发明授权

US06234965B1 Methods and apparatus for improving biochemical based therapy in humans 失效
标题翻译：改善人体生物化学疗法的方法与装置
公开(公告)号：US06234965B1
公开(公告)日：2001-05-22
申请号：US09052838
申请日：1998-03-31
申请人： Steven L. Miller , Michael M. Merzenich , Bret E. Peterson
发明人： Steven L. Miller , Michael M. Merzenich , Bret E. Peterson
IPC分类号： A61B500
CPC分类号： G06F19/3456 , G06F19/00
摘要： A computer-implemented method for improving biochemical-based therapy, or other forms of therapy such as surgery or radiation, in a human. Using the biochemical-based therapy for discussion, the computer-implemented method may include administering, using a computer, a first stimulus/response exercise to the human to measure at least one of an efficacy of the biochemical portion on the human and an undesirable side effect of the biochemical portion on the human. If the administering the first stimulus/response exercise measures the efficacy of the biochemical portion on the human, the method further includes improving the efficacy of the biochemical portion on the human by identifying a second stimulus/response exercise that at least maintains the efficacy of the biochemical portion on the human, and administering, using the computer, the second stimulus/response exercise to the human. If the administering the first stimulus/response exercise measures the undesirable effect of the biochemical portion on the human, reducing the undesirable effect of the biochemical portion on the human by identifying a third stimulus/response exercise that reduces the undesirable side effect of the biochemical portion on the human, and administering, using the computer, the third stimulus/response exercise to the human.
摘要翻译：用于改善人类基于生物化学疗法或其他形式的治疗如手术或放射的计算机实现的方法。使用基于生物化学的疗法进行讨论，计算机实施的方法可以包括使用计算机向人施用第一刺激/应答运动以测量生物化学部分对人类和不期望的一方的功效中的至少一个生化部分对人体的作用。如果施用第一刺激/应答运动测量生物化学部分对人的功效，则该方法还包括通过鉴定至少维持其功效的第二刺激/反应运动来提高生化部分对人的功效生物化学部分，并使用计算机向人类施用第二次刺激/应答运动。如果施用第一刺激/反应运动测量生物化学部分对人体的不良影响，则通过鉴定减少生物化学部分的不期望的副作用的第三刺激/反应运动来减少生化部分对人的不良影响使用电脑对人类进行第三次刺激/反应。

23. 发明授权

US06168562A Method and apparatus for dynamically tailoring biochemical based therapy programs in human 失效
标题翻译：用于动态剪裁人体生物化学疗法的方法和装置
公开(公告)号：US06168562A
公开(公告)日：2001-01-02
申请号：US09100663
申请日：1998-06-18
申请人： Steven L. Miller , Michael M. Merzenich , Bret E. Peterson
发明人： Steven L. Miller , Michael M. Merzenich , Bret E. Peterson
IPC分类号： A61N500
CPC分类号： G06F19/3456 , G06F19/00
摘要： The invention relates, in one embodiment to a computer-implemented method for dynamically tailoring dosages of a biochemical compound administered to a human under a biochemical-based therapy program. The method includes administering a first plurality of stimulus exercises to the human over a period of time. The first plurality of stimulus exercises are administered to the human after at least one administration of the biochemical compound. The method also includes measuring responses from the first plurality of stimulus exercises to assess efficacy levels of the biochemical portion on the human as a function of time over the period of time. The method further includes dynamically modulating the dosages of the biochemical compound responsive to the efficacy levels measured from the first plurality of stimulus exercises. The modulating results in a first dosage configured to be administered to the human at a first administration time and a second dosage different from the first dosage configured to be administered to the human at a second administration time different from the first administration time.
摘要翻译：在一个实施方案中，本发明涉及一种用于在基于生物化学的治疗程序下动态调整施用于人的生化化合物的剂量的计算机实现的方法。该方法包括在一段时间内向人施用第一组多个刺激锻炼。在生化化合物的至少一次给药后，首先对人施用第一组刺激作用。该方法还包括测量来自第一组多次刺激锻炼的反应，以评估生物化学部分对人的功效水平作为一段时间内的时间的函数。所述方法还包括响应于从第一次多次刺激锻炼测量的功效水平动态地调节生化化合物的剂量。所述调节导致配制为在第一施用时间下施用于人的第一剂量和不同于构建成在不同于第一给药时间的第二施用时间施用于人的第一剂量的第二剂量。

24. 发明授权

US06280198B1 Remote computer implemented methods for cognitive testing 有权
标题翻译：远程计算机实现认知测试的方法
公开(公告)号：US06280198B1
公开(公告)日：2001-08-28
申请号：US09241362
申请日：1999-01-29
申请人： Barbara Calhoun , Bret E. Peterson , Michael M. Merzenich
发明人： Barbara Calhoun , Bret E. Peterson , Michael M. Merzenich
IPC分类号： G09B1900
CPC分类号： A61B5/16 , A61B5/0022 , A61B5/4839 , G06F19/00 , G16H40/67
摘要： The invention relates to a computer implemented method for remotely administering and monitoring cognitive tests on a person using a computer network having a remote computer and a remote administering computer. The computer-implemented method includes administering a set of baseline cognitive tests to the person. The method further includes repeatedly administering a set of cognitive tests, obtaining a performance response of the person to the tests and uploading the testing information via the computer network. The method may also include monitoring the performance of the person. A database may be built from the performance response of multiple persons. The computer-implemented method includes administration using at least two computers where at least one is local and the other is remote.
摘要翻译：本发明涉及一种用于远程管理和监视使用具有远程计算机和远程管理计算机的计算机网络的人的认知测试的计算机实现的方法。计算机实现的方法包括向该人管理一组基线认知测试。该方法还包括重复地进行一组认知测试，获得该人对该测试的性能响应并通过该计算机网络上传测试信息。该方法还可以包括监视该人的表现。数据库可以根据多人的性能响应构建。计算机实现的方法包括使用至少两个计算机的管理，其中至少一个是本地的，另一个是远程的。

25. 发明授权

US6155971A Computer implemented methods for reducing the effects of tinnitus 有权
标题翻译：计算机实现减少耳鸣效应的方法
公开(公告)号：US6155971A
公开(公告)日：2000-12-05
申请号：US240066
申请日：1999-01-29
申请人： Barbara Calhoun , Bret E. Peterson , Michael M. Merzenich
发明人： Barbara Calhoun , Bret E. Peterson , Michael M. Merzenich
IPC分类号： A61B5/12 , A61F11/00 , A61M21/00
CPC分类号： A61B5/121 , A61B5/128 , A61F11/00
摘要： A computer-implemented method for diagnosing and/or treating tinnitus in a human subject is disclosed. The method includes generating tonal stimuli for characterizing the intensity and frequency range of the tinnitus. The method further includes generating a set of tonal stimuli used in tests comprised of tasks designed to treat the tinnitus of the human subject. The tests may be readministered at varying levels of difficulty based on the performance of the human subject. The computer-implemented method further includes providing the set of tests to the human being and receiving a response from the human being. The response from the human subject is compared to a performance threshold before potential modification of the tests. The computer-implemented method includes administration using at least two computers where at least one is local and the other is remote.
摘要翻译：公开了一种用于诊断和/或治疗人类受试者的耳鸣的计算机实现的方法。该方法包括产生用于表征耳鸣的强度和频率范围的音调刺激。该方法还包括产生一组音调刺激，其用于包括设计用于治疗人类受试者的耳鸣的任务的测试。可以基于人类受试者的表现以不同难度的级别重新评估测试。计算机实现的方法还包括向人类提供该组测试并且接收来自人的响应。在潜在修改测试之前，将人体对象的反应与性能阈值进行比较。计算机实现的方法包括使用至少两个计算机的管理，其中至少一个是本地的，另一个是远程的。

26. 发明授权

US06565359B2 Remote computer-implemented methods for cognitive and perceptual testing 有权
标题翻译：远程计算机实现的认知和感知测试方法
公开(公告)号：US06565359B2
公开(公告)日：2003-05-20
申请号：US09492259
申请日：2000-01-27
申请人： Barbara Calhoun , Bret E. Peterson , Michael M. Merzenich
发明人： Barbara Calhoun , Bret E. Peterson , Michael M. Merzenich
IPC分类号： G09B1900
CPC分类号： G06F19/3418 , A61B5/0022 , A61B5/16 , A61B5/4094
摘要： The present invention relates to a computer-implemented methods and apparatus for remote cognitive and/or perceptual testing using a computer network having a remote computer geographically separate from an administering computer. The remote cognitive and/or perceptual testing includes administering a set of cognitive and/or perceptual tests, obtaining a performance response of the person to the tests and uploading the testing information via the computer network. The tests may be administered a number of times to evaluate one or more cognitive skills and/or perceptual abilities. Parallel to the testing, a therapy may be administered. The method may also include monitoring the performance of the person on the tests. The computer-implemented method may additionally include administering a set of initial tests before therapy inception to assess a person's intrinsic cognitive skills and/or perceptual abilities. The results of the initial testing and testing during therapy may be entered into a database. The database may be built from the performance response of multiple people and may be useful in predicting efficacy of a proposed therapy.
摘要翻译：本发明涉及一种使用计算机网络进行远程认知和/或感知测试的计算机实现的方法和装置，所述计算机网络具有与管理计算机地理上分离的远程计算机。远程认知和/或感知测试包括管理一组认知和/或感知测试，获得该人对测试的性能响应并且经由计算机网络上传测试信息。测试可以多次施用以评估一种或多种认知技能和/或感知能力。与测试并行，可以进行治疗。该方法还可以包括监测人在测试中的表现。计算机实现的方法可以另外包括在治疗开始之前施用一组初始测试以评估个人的内在认知技能和/或感知能力。治疗期间的初始测试和测试的结果可以输入到数据库中。数据库可以根据多个人的绩效响应构建，并且可用于预测所提出的治疗的功效。

27. 发明授权

US06267733B1 Apparatus and methods for treating motor control and somatosensory perception deficits 有权
标题翻译：用于治疗运动控制和躯体感觉缺陷的装置和方法
公开(公告)号：US06267733B1
公开(公告)日：2001-07-31
申请号：US09374227
申请日：1999-08-13
申请人： Bret E. Peterson , Barbara M. Calhoun , Michael Mathias Merzenich , William M. Jenkins , Nancy Byl , Srikantan Nagarajan
发明人： Bret E. Peterson , Barbara M. Calhoun , Michael Mathias Merzenich , William M. Jenkins , Nancy Byl , Srikantan Nagarajan
IPC分类号： A61B5103
CPC分类号： A61B5/4824 , A61B5/0053 , A61B5/0057 , A61B5/411 , A61B5/4827
摘要： The present invention describes computer-implemented methods and apparatus for treating motor control and somatosensory perception deficits. The motor control and somatosensory perception deficits may have their genesis in a wide variety of issues ranging from injury, disease, or a gradual degradation of motor control over time due to repetitive strain, for example. By administering a computer-implemented training regime directed to improve sensory feedback and motor control, abnormal motor control and somatosensory perception may be substantially improved. The computer-implemented training regime includes somatosensory perception and motor control exercises which may be flexibly administered. Several training apparatus are described for implementing the somatosensory perception and motor control exercises. The training apparatus described herein are capable of driving improvements in temporal, spatial and intensity resolution of somatosensory feedback. In addition, the apparatus allow the training to be monitored and adapted on a quantitative basis as treatment proceeds. Advantageously, this provides a more accurate and effective training tool for treating motor control deficits. Further, the computer-implemented methods and apparatus allow treatment to be administered in the convenience of the person's own home and on a daily basis.
摘要翻译：本发明描述了用于治疗运动控制和躯体感觉缺陷的计算机实现的方法和装置。运动控制和躯体感觉缺陷可能会在各种各样的问题上产生，例如，由于重复性应变，损伤，疾病或运动控制随时间的逐渐降低。通过实施针对改善感觉反馈和运动控制的计算机实施的培训制度，可以显着改善运动控制异常和躯体感觉感觉。计算机实施的培训制度包括可以灵活管理的体感感知和运动控制练习。描述了用于实施体感感知和运动控制练习的几种训练装置。本文描述的训练装置能够促进躯体感觉反馈的时间，空间和强度分辨率的改善。此外，该装置允许在治疗进行时在定量的基础上监测和调整训练。有利地，这提供了用于治疗运动控制缺陷的更准确和有效的训练工具。此外，计算机实施的方法和装置允许在人的家庭和每天的方便的情况下进行治疗。

28. 发明授权

US06289310B1 Apparatus for enhancing phoneme differences according to acoustic processing profile for language learning impaired subject 有权
标题翻译：用于根据语言学习受损主体的声学处理简档增强音素差异的装置
公开(公告)号：US06289310B1
公开(公告)日：2001-09-11
申请号：US09167279
申请日：1998-10-07
申请人： Steven L. Miller , Bret E. Peterson , Athanassios Protopapas
发明人： Steven L. Miller , Bret E. Peterson , Athanassios Protopapas
IPC分类号： G10L2102
CPC分类号： G10L13/033 , G10L13/00 , G10L2021/065
摘要： An apparatus and method for screening an individual's ability to process acoustic events is provided. The invention provides sequences (or trials) of acoustically processed target and distractor phonemes to a subject for identification. The acoustic processing includes amplitude emphasis of selected frequency envelopes, stretching (in the time domain) of selected portions of phonemes, and phase adjustment of selection portions of phonemes relative to a base frequency. After a number of trials, the method of the present invention develops a profile for an individual that indicates whether the individual's ability to process acoustic events is within a normal range, and if not, what processing can provide the individual with optimal hearing. The individual's profile can then be used by a listening or processing device to particularly emphasize, stretch, or otherwise manipulate an audio stream to provide the individual with an optimal chance of distinguishing between similar acoustic events.
摘要翻译：提供了一种用于筛选个人处理声学事件的能力的装置和方法。本发明提供了声学处理的目标和干扰素音素到受试者鉴定的序列（或试验）。声学处理包括所选择的频率包络的幅度强调，音素的选定部分的拉伸（在时域中）以及相对于基本频率的音素的选择部分的相位调整。经过多次试验之后，本发明的方法开发出一个个人的个人资料，该个人资料表明个人处理声音事件的能力是否在正常范围内，如果没有，哪些处理可以为个人提供最佳的听觉。然后，个人的个人资料可以由听力或处理装置使用，以特别强调，拉伸或以其它方式操纵音频流，以向个体提供区分相似声学事件的最佳机会。

29. 发明授权

US6036496A Universal screen for language learning impaired subjects 有权
标题翻译：语言学习通用屏障受损科目
公开(公告)号：US6036496A
公开(公告)日：2000-03-14
申请号：US167278
申请日：1998-10-07
申请人： Steven L. Miller , Bret E. Peterson , Athanassios Protopapas
发明人： Steven L. Miller , Bret E. Peterson , Athanassios Protopapas
IPC分类号： G09B19/04 , G09B21/00 , G09B19/00 , G06K9/00 , G09B1/00 , G09B19/06
CPC分类号： G09B19/04 , G09B21/009
摘要： An apparatus and method for screening an individual's ability to process acoustic events is provided. The invention provides sequences (or trials) of acoustically processed target and distractor phonemes to a subject for identification. The acoustic processing includes amplitude emphasis of selected frequency envelopes, stretching (in the time domain) of selected portions of phonemes, and phase adjustment of selection portions of phonemes relative to a base frequency. After a number of trials, the method of the present invention develops a profile for an individual that indicates whether the individual's ability to process acoustic events is within a normal range, and if not, what processing can provide the individual with optimal hearing. The individual's profile can then be used by a listening or processing device to particularly emphasize, stretch, or otherwise manipulate an audio stream to provide the individual with an optimal chance of distinguishing between similar acoustic events.
摘要翻译：提供了一种用于筛选个人处理声学事件的能力的装置和方法。本发明提供了声学处理的目标和干扰素音素到受试者鉴定的序列（或试验）。声学处理包括所选择的频率包络的幅度强调，音素的选定部分的拉伸（在时域中）以及相对于基本频率的音素的选择部分的相位调整。经过多次试验之后，本发明的方法开发出一个个人的个人资料，该个人资料表明个人处理声音事件的能力是否在正常范围内，如果没有，哪些处理可以为个人提供最佳的听觉。然后，个人的个人资料可以由听力或处理装置使用，以特别强调，拉伸或以其它方式操纵音频流，以向个体提供区分相似声学事件的最佳机会。

30. 发明申请

US20130325920A1 System and Method for Sharing Geospatial Assets Between Local Devices 有权
标题翻译：本地设备之间共享地理空间资产的系统和方法
公开(公告)号：US20130325920A1
公开(公告)日：2013-12-05
申请号：US13483215
申请日：2012-05-30
申请人： Bret E. Peterson , Eli Dylan Lorimer , Stephen Joseph Potell
发明人： Bret E. Peterson , Eli Dylan Lorimer , Stephen Joseph Potell
IPC分类号： G06F15/16
CPC分类号： H04L67/1068 , H04L29/08072 , H04L67/104 , H04L67/1093
摘要： A system and method for sharing geospatial assets between local devices is disclosed. In one embodiment, the method may generally include storing a geospatial asset on a first local device. The first local device may include a processor and memory storing instructions that, when executed by the processor, configures the first local device to act as a local server. The method may also include transmitting with the local server data indicating the availability of the geospatial asset to be shared, receiving from a second local device a request to share the geospatial asset and sharing the geospatial asset with the second local device.
摘要翻译：公开了一种在本地设备之间共享地理空间资产的系统和方法。在一个实施例中，该方法通常可以包括将地理空间资产存储在第一本地设备上。第一本地设备可以包括处理器和存储指令的存储器，所述指令在由处理器执行时将第一本地设备配置为充当本地服务器。该方法还可以包括用本地服务器传送指示要共享的地理空间资产的可用性的数据，从第二本地设备接收共享地理空间资产的请求并与第二本地设备共享地理空间资产。

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