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    • 24. 发明授权
    • Method of measuring blood clotting time
    • 测量血液凝固时间的方法
    • US4217107A
    • 1980-08-12
    • US944783
    • 1978-09-22
    • Yukio SaitoKoichi SekiyaMasaaki Takahashi
    • Yukio SaitoKoichi SekiyaMasaaki Takahashi
    • G01N33/86G01N33/49G01N33/16
    • G01N33/4905
    • A blood clotting end point detector which includes means for monitoring an electrical signal representing the value A of one or more optical properties of a blood plasma sample to which a coagulating agent has been added, means for deriving the first and the second differentials with respect to time of the value A, means for detecting the moment Ta when the second differential changes from negative to positive or becomes positive, means for detecting the moment Tb when the second differential next changes from positive to negative, means for deriving the difference (R) between the tangent to the curve A at the moment Ta and the curve A, means for determining whether the difference (R) or the integral, with respect to time from moment Ta to moment Tb, of the difference (R) exceeds a predetermined threshold value, in which case moment Tb is taken as the true clotting end point.
    • 一种血液凝固终点检测器,其包括用于监测表示已经加入凝血剂的血浆样品的一种或多种光学性质的值A的电信号的装置,用于相对于第一和第二差分 值A的时间,当第二差分从负变为正或变为正时检测力矩Ta的装置,用于当第二差分接下来从正变为负检测时刻Tb的装置,用于导出差R的装置, 在时刻Ta与曲线A之间的曲线A的切线之间,确定差值(R)相对于时刻Ta到时刻Tb的时间差(R)或积分是否超过预定阈值的装置 值,在这种情况下,将Tb作为真正的凝血终点。