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11. 发明授权

US5667989A Fungal cell wall Protein CLY4 失效
标题翻译：真菌细胞壁蛋白CLY4
公开(公告)号：US5667989A
公开(公告)日：1997-09-16
申请号：US414685
申请日：1995-03-31
申请人： John E. McCullough , Judith Baymiller
发明人： John E. McCullough , Judith Baymiller
IPC分类号： G01N33/53 , A61K38/00 , C07K14/395 , C12N1/19 , C12N15/09 , C12N15/31 , C12P21/02 , C12Q1/68 , C12R1/865 , G01N33/566 , C07H21/04 , C12N1/21 , C12N15/63
CPC分类号： C07K14/395 , A61K38/00
摘要： CLY4 gene, protein, vectors, and host cells. The gene product pCly4 is involved in fungal cell wall biosynthesis, making it a useful target for anti-fungal agents.
摘要翻译： CLY4基因，蛋白质，载体和宿主细胞。基因产物pCly4参与真菌细胞壁生物合成，使其成为抗真菌剂的有用靶标。

12. 发明授权

US4554250A Method of increased production of penicillin acylase and plasmid employed therein 失效
标题翻译：增加青霉素酰基转移酶和其中使用的质粒产量的方法
公开(公告)号：US4554250A
公开(公告)日：1985-11-19
申请号：US509501
申请日：1983-06-30
申请人： John E. McCullough
发明人： John E. McCullough
IPC分类号： C12N1/20 , C12N1/21 , C12N9/84 , C12N15/09 , C12R1/11 , C12N15/00 , C12N1/00 , C12N9/86
CPC分类号： C12N9/84 , Y10S435/837
摘要： A method is provided for enhancing penicillin acylase production wherein a Bacillus subtilis plasmid containing an insert of a chromosomal DNA fragment of Bacillus megaterium which includes the appropriate gene for enhancing penicillin acylase production is cloned into Bacillus megaterium and the Bacillus megaterium containing the above plasmid is employed in the production of penicillin acylase.A plasmid method for forming same and host plasmid combination which are useful in the above method are also provided.
摘要翻译：提供了一种用于增强青霉素酰基转移酶产生的方法，其中将含有包含用于增强青霉素酰基转移酶产生的适当基因的巨大芽孢杆菌的染色体DNA片段的插入片段的枯草芽孢杆菌质粒克隆到巨大芽孢杆菌中，并且使用含有上述质粒的巨大芽孢杆菌在青霉素酰化酶的生产中。还提供了用于形成上述方法的质粒方法和宿主质粒组合。

13. 发明授权

US4192152A Scroll-type fluid displacement apparatus with peripheral drive 失效
标题翻译：带外围驱动的涡旋式流体置换设备
公开(公告)号：US4192152A
公开(公告)日：1980-03-11
申请号：US896161
申请日：1978-04-14
申请人： Allen E. Armstrong , John E. McCullough
发明人： Allen E. Armstrong , John E. McCullough
IPC分类号： F01C1/02 , F25B1/04 , F01C11/00 , F01C21/00 , F25D17/00
CPC分类号： F01C1/0238 , F02G2250/03 , F25B1/04 , F25B2400/14
摘要： Peripherally-driven scroll apparatus. The orbiting scroll member is attached through radially-compliant linking means to eccentrics mounted on three equally spaced crankshafts to accommodate differential thermal expansion without the generation of any appreciable elastic forces to increase bearing loads. Means are provided to prevent axial deflections in the stationary scroll members while permitting their supports to be designed and constructed for strength rather than stiffness. The apparatus may be staged and employed as a compressor or expander.
摘要翻译：外围驱动的滚动装置。绕动涡旋件通过径向顺应的连接装置附接到安装在三个等间隔的曲轴上的偏心件，以适应不同的热膨胀，而不产生任何明显的弹性力以增加轴承负载。提供装置以防止固定涡旋构件中的轴向偏转，同时允许其支撑件被设计和构造用于强度而不是刚度。该装置可以分段并用作压缩机或膨胀机。

14. 发明授权

US4121438A Coupling member for orbiting machinery 失效
标题翻译：轨道机械联轴器
公开(公告)号：US4121438A
公开(公告)日：1978-10-24
申请号：US722713
申请日：1976-09-13
申请人： John E. McCullough
发明人： John E. McCullough
IPC分类号： F04D29/043 , F01C1/02 , F01C17/06 , F03C2/02 , F04C2/02 , F04C18/02 , F16D3/04
CPC分类号： F01C17/066 , F16D3/04
摘要： A coupling member particularly suited for coupling two components in a predetermined angular relationship while one component is orbited relative to the other. The coupling member comprises a ring having pairs of oppositely disposed keys on opposite annular surfaces, one pair of keys being displaced 90.degree. from the other. The keys are held on pivot pins affixed to the ring, the pivot pins preferably having flanges which are set in counterbores in the ring. A plurality of axial force-stabilizing disks are also inset on the annular ring surfaces.
摘要翻译：一种联接构件，其特别适用于在一个构件相对于另一构件绕轨道运动时以预定的角度关系耦合两个构件。联接构件包括在相对的环形表面上具有成对的相对设置的键的环，一对键从另一个90度移位。钥匙被保持在固定到环上的枢轴销上，枢轴销优选地具有设置在环中的沉孔中的凸缘。多个轴向力稳定盘也嵌在环形环表面上。

15. 发明授权

US3994636A Axial compliance means with radial sealing for scroll-type apparatus 失效
标题翻译：轴向顺从性意味着滚动式设备具有径向密封
公开(公告)号：US3994636A
公开(公告)日：1976-11-30
申请号：US561479
申请日：1975-03-24
申请人： John E. McCullough , Robert W. Shaffer
发明人： John E. McCullough , Robert W. Shaffer
IPC分类号： F04C2/02 , F01C1/02 , F01C19/08 , F03C2/02 , F04C2/04 , F04C18/02 , F04C17/02
CPC分类号： F01C19/08 , F01C1/0215 , F04C2230/60 , F05B2230/60
摘要： Axial compliance/sealing means are provided for scroll-type apparatus. These means comprise seal elements associated with the involute wraps which are urged by an axial force to make sealing contact with the end plates of the opposing scroll members. The axial force may be pneumatically or mechanically applied and the resulting axial contact is of such a nature as to maintain the integrity of the radial sealing within the apparatus. The use of the axial compliance/sealing means allows the contacting surfaces through which radial sealing is effected to be machined to conventional accuracy, and provides automatic compensation for temperature differentials within the apparatus as well for any uneven wear of the scroll members.
摘要翻译：为涡旋式装置提供轴向顺应性/密封装置。这些装置包括与渐开线圈相关联的密封元件，其被轴向力推动以与相对的涡旋构件的端板密封接触。轴向力可以是气动的或机械地施加的，并且所产生的轴向接触具有这样的性质，即保持设备内的径向密封的完整性。使用轴向顺应性/密封装置允许通过其进行径向密封的接触表面被加工成常规精度，并且对于装置内的温度差以及对于涡卷构件的任何不均匀磨损提供自动补偿。

16. 发明授权

US6139828A Hair care formulations 有权
标题翻译：头发护理配方
公开(公告)号：US6139828A
公开(公告)日：2000-10-31
申请号：US324283
申请日：1999-06-02
申请人： John E. McCullough
发明人： John E. McCullough
IPC分类号： A61K8/46 , A61K8/97 , A61K36/537 , A61K36/886 , A61Q5/02 , A61K7/075 , A61K7/08
CPC分类号： A61K8/97 , A61K8/466 , A61Q5/02
摘要： Hair care formulations for cleansing the scalp and hair follicle openings are disclosed which comprises black cohosh extract, and a surfactant selected from the group consisting of sodium C.sub.14-16 olefin sulfonate, sodium lauryl sulfoacetate, disodium laureth sulfosuccinate and combinations thereof
摘要翻译：公开了用于清洁头皮和毛囊开口的头发护理配方，其包含黑色高丝提取物和选自C14-16烯烃磺酸钠，月桂基磺基乙酸钠，月桂基聚氨酯磺基琥珀酸二钠及其组合的表面活性剂

17. 发明授权

US5314316A Scroll apparatus with reduced inlet pressure drop 失效
标题翻译：减压入口压降的涡旋式装置
公开(公告)号：US5314316A
公开(公告)日：1994-05-24
申请号：US965150
申请日：1992-10-22
申请人： Yoshitaka Shibamoto , Hiroyuki Taniwa , Hiromichi Ueno , Shigeki Hagiwara , Ronald J. Forni , John E. McCullough
发明人： Yoshitaka Shibamoto , Hiroyuki Taniwa , Hiromichi Ueno , Shigeki Hagiwara , Ronald J. Forni , John E. McCullough
IPC分类号： F01C1/02 , F04C18/02
CPC分类号： F04C18/023 , F04C18/0246 , F04C2250/101 , F05B2250/501
摘要： A scroll type fluid machinery which is provided with: a first scroll and a second scroll which moves with respect to the first scroll, where the base of the first scroll is provided with suction bores perforating through the base from the rear surface thereof to the front surface, and open at the outer peripheral portion of the front surface of the base, so that fluid released into an internal space of the body casing passes through the suction bores, and into the suction sides of compression volumes formed between spiral members of the scrolls, whereby suction pressure in the compression volumes is maximized and volumetric efficiency is improved.
摘要翻译：一种涡旋式流体机械，其设置有：第一涡旋件和第二涡旋件，其相对于第一涡旋件移动，第一涡旋件的基部设置有从其后表面穿过基座的吸入孔，表面，并且在基座的前表面的外周部分开口，使得释放到主体壳体的内部空间中的流体通过吸入孔，并进入形成在涡旋件的螺旋构件之间的压缩体积的吸力侧从而使压缩体积中的吸入压力最大化并提高体积效率。

18. 发明授权

US5256042A Bearing and lubrication system for a scroll fluid device 失效
标题翻译：涡旋流体装置的轴承和润滑系统
公开(公告)号：US5256042A
公开(公告)日：1993-10-26
申请号：US837979
申请日：1992-02-20
申请人： John E. McCullough , Ronald J. Forni , Robert M. Lucas
发明人： John E. McCullough , Ronald J. Forni , Robert M. Lucas
IPC分类号： F04C18/02 , F04C28/28 , F04C29/02 , F01C1/04 , F01C21/04
CPC分类号： F04C29/025 , F04C18/023
摘要： A bearing and lubrication system for a sealed, integrated motor driven co-rotating scroll refrigerant compressor includes hydrostatic bearings and an independent motor driven lubricant supply pump for supplying lubricant to the hydrostatic bearings mounting in the housing. The housing is divided into a high-pressure section that receives compressed refrigerant and a low pressure section containing the involute scroll compressor wraps. Individual lubricant supply sumps are provided in the high and lower pressure housing sections for supplying lubricant to the compressor bearings. The lubricant pump is capable of drawing lubricant from one or both of the lubricant supply sumps. A lubricant level sensor associated with one of the low or high pressure housing sumps is provided to maintain a desired level of lubricant therein. The lubricant supply pump is controlled so that pressure is supplied to the hydrostatic bearings during compressor operation. The lubricant may be pressurized by compressed refrigerant in the high-pressure housing section for supply to the compressor bearings with or without operation of the lubricant supply pump.
摘要翻译：用于密封的一体式马达驱动的同向旋转涡旋制冷剂压缩机的轴承和润滑系统包括静压轴承和用于将润滑剂供应到安装在壳体中的静压轴承的独立的马达驱动的润滑剂供应泵。壳体被分为接收压缩制冷剂的高压部分和包含渐开线涡旋压缩机涡卷的低压部分。在高压和低压壳体部分提供单独的润滑剂供应池，用于向压缩机轴承供应润滑剂。润滑剂泵能够从一个或两个润滑剂供应池抽取润滑剂。提供与低压或高压壳体中的一个相关联的润滑剂液位传感器以保持其中所需的润滑剂水平。控制润滑剂供应泵，以便在压缩机运行期间向静压轴承提供压力。润滑剂可以通过高压壳体部分中的压缩制冷剂被加压，以在具有或不具有润滑剂供应泵的操作的情况下供应到压缩机轴承。

19. 发明授权

US4754018A Antibiotic prepared from lysobacter sp. SC 14,067 and analogs thereof 失效
标题翻译：溶解细菌制备的抗生素 SC 14,067及其类似物
公开(公告)号：US4754018A
公开(公告)日：1988-06-28
申请号：US23425
申请日：1987-03-09
申请人： Adrienne A. Tymiak , Donald R. Kirsch , Joseph O'Sullivan , John E. McCullough
发明人： Adrienne A. Tymiak , Donald R. Kirsch , Joseph O'Sullivan , John E. McCullough
IPC分类号： C07G11/00 , A61K35/74 , A61P31/04 , C12P1/04 , C12R1/01 , C07K5/12
CPC分类号： C12P1/04 , Y10S930/19
摘要： A novel antibiotic substance EM5587 is prepared by cultivation of a strain of the microorganism Lysobacter sp. SC 14,067, A.T.C.C. No. 53042. Chemical analogs of EM5587 are prepared by chemical synthesis.
摘要翻译：通过培养微生物溶菌杆菌属菌株制备新型抗生素物质EM5587。 SC 14,067，A.T.C.C. 号53042.通过化学合成制备EM5587的化学类似物。

20. 发明授权

US4463591A Method of fabricating scroll members by coining and tools therefor 失效
标题翻译：通过压印制造滚动件的方法及其工具
公开(公告)号：US4463591A
公开(公告)日：1984-08-07
申请号：US488469
申请日：1983-04-25
申请人： John E. McCullough
发明人： John E. McCullough
IPC分类号： B23P9/00 , B23P15/00 , B21D22/00 , B21D17/02 , B21D31/00
CPC分类号： B23P9/00 , B23P15/00
摘要： Method for forming scroll members comprising an end plate having an involute wrap rigidly affixed thereto. The end plate and involute wrap are precision formed, e.g., by casting, either as an integral element or as two separate elements and then the scroll member is coined to the desired dimensional accuracy and finish. If a separate end plate and an involute wrap are provided for coining, then they are rigidly joined during coining, an embodiment which permits the use of two different materials and/or the attainment of two different surface characteristics for the involute wrap and the end plate.
摘要翻译：用于形成涡卷构件的方法，其包括具有刚性地固定到其上的渐开线涡卷的端板。端板和渐开线包被精确地形成，例如通过铸造，作为整体元件或作为两个分开的元件，然后涡旋构件被制造成所需的尺寸精度和光洁度。如果设置单独的端板和渐开线包装用于压印，则在压印期间它们刚性地接合，允许使用两种不同材料和/或获得两种不同表面特性的渐开线包裹体和端板的实施例。

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