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11. 发明授权

US07826070B2 Scanning optical system adjusting device and scanning optical system adjusting method 有权
标题翻译：扫描光学系统调整装置和扫描光学系统调整方法
公开(公告)号：US07826070B2
公开(公告)日：2010-11-02
申请号：US11840374
申请日：2007-08-17
申请人： Wataru Watanabe , Kazutoshi Takahashi
发明人： Wataru Watanabe , Kazutoshi Takahashi
IPC分类号： G01B11/14
CPC分类号： G02B26/127
摘要： As a light beam of a scanning optical system unit is adjusted in the state where the scanning optical system unit is assembled, its adjustment work and the assembly work of the scanning optical system are prevented from being useless. Thus, a scanning optical system adjusting device which can adjust the scanning optical system quickly and at a low cost is to be provided. A scanning optical system adjusting device according to the invention includes a static angle control unit configured to maintain a rotation angle of a rotary polygon mirror in the assembly unit of the scanning optical system at a predetermined angle and make the rotary polygon mirror static there, and a light beam parameter measuring unit configured to measure a predetermined parameter of a light beam reflected by the rotary polygon mirror maintained at the predetermined angle by the static angle control unit.
摘要翻译：由于在组装扫描光学系统单元的状态下调整扫描光学系统单元的光束，所以防止其调整工作和扫描光学系统的组装工作变得无用。因此，可以提供能够快速且低成本地调整扫描光学系统的扫描光学系统调整装置。根据本发明的扫描光学系统调节装置包括静态角度控制单元，其构造成将扫描光学系统的组装单元中的旋转多面镜的旋转角度保持在预定角度，并使旋转多面体镜静止，光束参数测量单元，被配置为测量由所述静态角度控制单元维持在所述预定角度的由所述旋转多面镜反射的光束的预定参数。

12. 发明申请

US20090046341A1 SCANNING OPTICAL SYSTEM ADJUSTING DEVICE AND SCANNING OPTICAL SYSTEM ADJUSTING METHOD 有权
标题翻译：扫描光学系统调整设备和扫描光学系统调整方法
公开(公告)号：US20090046341A1
公开(公告)日：2009-02-19
申请号：US11840374
申请日：2007-08-17
申请人： Wataru Watanabe , Kazutoshi Takahashi
发明人： Wataru Watanabe , Kazutoshi Takahashi
IPC分类号： G02B26/12
CPC分类号： G02B26/127
摘要： As a light beam of a scanning optical system unit is adjusted in the state where the scanning optical system unit is assembled, its adjustment work and the assembly work of the scanning optical system are prevented from being useless. Thus, a scanning optical system adjusting device which can adjust the scanning optical system quickly and at a low cost is to be provided. A scanning optical system adjusting device according to the invention includes a static angle control unit configured to maintain a rotation angle of a rotary polygon mirror in the assembly unit of the scanning optical system at a predetermined angle and make the rotary polygon mirror static there, and a light beam parameter measuring unit configured to measure a predetermined parameter of a light beam reflected by the rotary polygon mirror maintained at the predetermined angle by the static angle control unit.
摘要翻译：由于在组装扫描光学系统单元的状态下调整扫描光学系统单元的光束，所以防止其调整工作和扫描光学系统的组装工作变得无用。因此，可以提供能够快速且低成本地调整扫描光学系统的扫描光学系统调整装置。根据本发明的扫描光学系统调节装置包括静态角度控制单元，其构造成将扫描光学系统的组装单元中的旋转多面镜的旋转角度保持在预定角度，并使旋转多面体镜静止，光束参数测量单元，被配置为测量由所述静态角度控制单元维持在所述预定角度的由所述旋转多面镜反射的光束的预定参数。

13. 发明申请

US20090045324A1 SCANNING OPTICAL SYSTEM MEASURING DEVICE AND SCANNING OPTICAL SYSTEM MEASURING METHOD 失效
标题翻译：扫描光学系统测量装置和扫描光学系统测量方法
公开(公告)号：US20090045324A1
公开(公告)日：2009-02-19
申请号：US11840372
申请日：2007-08-17
申请人： Wataru Watanabe , Takahiro Chikuda
发明人： Wataru Watanabe , Takahiro Chikuda
IPC分类号： G01J1/42
CPC分类号： G01J1/4257 , G01J1/46 , G02B26/127 , H04N1/0473 , H04N1/1135 , H04N2201/04713 , H04N2201/04729 , H04N2201/04731 , H04N2201/04734 , H04N2201/04744
摘要： Measurement of a scanning optical system is to be carried out simply and easily. According to the invention, a scanning optical system measuring device for making adjustment of a scanning optical system which performs scanning with a light beam, includes: plural one-dimensional position detection devices provided at a distance from each other in a scanning direction of a light beam caused to perform scanning, and arranged to intersect the scanning direction of the light beam, and configured to output light receiving position of the light beam caused to perform scanning, as an analog signal; and a detection signal processing unit configured to detect scanning state of the light beam on the basis of a detection signal of the one-dimensional position detection devices.
摘要翻译：扫描光学系统的测量应简单而容易地进行。根据本发明，一种用于进行用光束进行扫描的扫描光学系统的调整的扫描光学系统测量装置包括：多个一维位置检测装置，其沿光的扫描方向彼此间隔设置光束进行扫描，并被布置为与光束的扫描方向相交，并且被配置为输出引起进行扫描的光束的光接收位置作为模拟信号; 以及检测信号处理单元，其被配置为基于所述一维位置检测装置的检测信号来检测所述光束的扫描状态。

14. 发明授权

US07211572B2 Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor 有权
标题翻译：含氮稠环化合物及其作为HIV整合酶抑制剂的用途
公开(公告)号：US07211572B2
公开(公告)日：2007-05-01
申请号：US11255605
申请日：2005-10-13
申请人： Susumu Miyazaki , Susumu Katoh , Kaoru Adachi , Hirotaka Isoshima , Satoru Kobayashi , Yuji Matsuzaki , Wataru Watanabe , Kazunobu Yamataka , Shinichi Kiyonari , Shuichi Wamaki
发明人： Susumu Miyazaki , Susumu Katoh , Kaoru Adachi , Hirotaka Isoshima , Satoru Kobayashi , Yuji Matsuzaki , Wataru Watanabe , Kazunobu Yamataka , Shinichi Kiyonari , Shuichi Wamaki
IPC分类号： A01N43/00 , A01N43/58 , A61K31/55 , A61K31/553 , A61K31/554
CPC分类号： C07D471/04 , C07D487/04
摘要： The present invention relates to a nitrogen-containing fused ring compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof, and an anti-HIV agent containing such compound. The compound of the present invention has an HIV integrase inhibitory activity, and is useful as an agent for the prophylaxis or treatment of AIDS, or as an anti-HIV agent. In addition, by the combined use with other anti-HIV agents such as a protease inhibitor, a reverse transcriptase inhibitor and the like, it can be a more effective anti-HIV agent. Because it shows integrase-specific high inhibitory activity, the compound can be a pharmaceutical agent safe on human body, which causes only a fewer side effects.
摘要翻译：本发明涉及由下式[I]表示的含氮稠环化合物，其中每个符号如说明书中所定义，或其药学上可接受的盐和含有该化合物的抗HIV剂。本发明的化合物具有HIV整合酶抑制活性，可用作预防或治疗AIDS或作为抗HIV剂的药剂。此外，通过与其它抗HIV剂如蛋白酶抑制剂，逆转录酶抑制剂等的组合使用，它可以是更有效的抗HIV剂。因为它显示出整合酶特异性的高抑制活性，所以化合物可以是对人体安全的药剂，其副作用较小。

15. 发明申请

US20050288326A1 Combination therapy 有权
标题翻译：联合治疗
公开(公告)号：US20050288326A1
公开(公告)日：2005-12-29
申请号：US11133463
申请日：2005-05-20
申请人： Yuji Matsuzaki , Wataru Watanabe , Satoru Ikeda , Mitsuki Kano
发明人： Yuji Matsuzaki , Wataru Watanabe , Satoru Ikeda , Mitsuki Kano
IPC分类号： A61K31/47 , A61K31/472 , A61K31/496 , A61K31/506 , A61K31/52 , A61K31/536 , A61K31/7072
CPC分类号： A61K31/7072 , A61K31/39 , A61K31/47 , A61K31/472 , A61K31/496 , A61K31/506 , A61K31/52 , A61K31/536 , A61K31/675 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a combination therapy for treating an HIV infection or inhibiting integrase comprising (S)-6-(3-Chloro-2-fluorobenzyl)-1-(1-hydroxymethyl-2-methylpropyl)-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (“Compound A”) or a pharmaceutically acceptable solvate or salt thereof in combination with at least one other anti-HIV agent. In some embodiments of the present invention, the other anti-HIV agents are chosen from reverse transcriptase inhibitors and protease inhibitors. In certain embodiments of the present invention, the other anti-HIV agents are chosen from AZT, 3TC, PMPA, efavirenz, indinavir, nelfinavir, a combination of AZT/3TC, and a combination of PMPA/3TC. Since Compound A has a high inhibitory activity specific for integrases, when used in combinations with other anti-HIV agents it can provide a combination therapy with fewer side effects for humans.
摘要翻译：本发明涉及用于治疗HIV感染或抑制整合酶的组合疗法，其包含（S）-6-（3-氯-2-氟苄基）-1-（1-羟甲基-2-甲基丙基）-7-甲氧基-4 - 氧代-1,4-二氢喹啉-3-羧酸（“化合物A”）或其药学上可接受的溶剂合物或其盐与至少一种其它抗HIV剂组合。在本发明的一些实施方案中，其它抗HIV剂选自逆转录酶抑制剂和蛋白酶抑制剂。在本发明的某些实施方案中，其它抗HIV剂选自AZT，3TC，PMPA，依法韦仑，茚地那韦，奈非那韦，AZT / 3TC的组合和PMPA / 3TC的组合。由于化合物A对整合酶具有高的抑制活性，因此当与其它抗HIV剂组合使用时，可以提供对人类副作用较少的组合疗法。

16. 发明授权

US5698580A Antiviral agent containing benzodithiin derivative as active ingredient 失效
标题翻译：含有苯并二硫杂衍生物作为有效成分的抗病毒剂
公开(公告)号：US5698580A
公开(公告)日：1997-12-16
申请号：US750730
申请日：1996-12-16
申请人： Tsuyoshi Kajiyashiki , Ryu Sato , Tomoyuki Yokota , Kenji Sudo , Wataru Watanabe , Shiro Shigeta
发明人： Tsuyoshi Kajiyashiki , Ryu Sato , Tomoyuki Yokota , Kenji Sudo , Wataru Watanabe , Shiro Shigeta
IPC分类号： A61K31/385 , A61P11/00 , A61P31/12 , C07D339/08
CPC分类号： C07D339/08
摘要： Antiviral agents comprising, as an active ingredient, a 1,4-dihydro-2,3-benzodithiin derivative of the formula ##STR1## wherein each symbol is as defined in the Specification, or a pharmacologically acceptable salt thereof. The antiviral agents of the present invention have superior antiviral activity and are effective for the preventive and therapeutic treatment of viral diseases caused typically by RS virus.
摘要翻译： PCT No.PCT / JP95 / 01107 Sec。 371日期1996年12月16日第 102（e）日期1996年12月16日PCT归档1995年6月6日PCT公布。出版物WO95 / 35292 日期1995年12月28日，含有式“IMAGE”的1,4-二氢-2,3-苯并二硫杂衍生物作为活性成分的抗病毒药物，其中每个符号如本说明书中所定义，或其药理学上可接受的盐。本发明的抗病毒剂具有优异的抗病毒活性，对通常由RS病毒引起的病毒性疾病的预防和治疗有效。

17. 发明授权

US08750764B2 Developing device and image forming apparatus 有权
标题翻译：显影装置和图像形成装置
公开(公告)号：US08750764B2
公开(公告)日：2014-06-10
申请号：US13350076
申请日：2012-01-13
申请人： Yuusuke Okuno , Wataru Watanabe
发明人： Yuusuke Okuno , Wataru Watanabe
IPC分类号： G03G15/08
CPC分类号： G03G15/0893 , G03G15/0189 , G03G2215/0132
摘要： A trickle-type developing device comprising: a stirring and conveying tank provided with stirring and conveying screws that circulate the developer; a discharge member via which a part of the developer is conveyed from the tank to a discharge opening through which the developer is discharged, the discharge opening being provided in the discharge member; and a reverse flow generating screw provided inside a portion of the discharge member, sharing one of rotation shafts of the stirring and conveying screws, and pushing back a part of the developer, wherein the portion has a reduced-radius part and in a cross section thereof perpendicular to an axial direction of the one of rotation shafts, an inner radius of the portion is smaller in the reduced-radius part than in the remaining part, the reduced-radius part being located in a lower part of the portion with respect to a vertical direction of the portion.
摘要翻译：一种涓流型显影装置，包括：搅拌输送箱，设有搅拌和输送螺旋，使显影剂循环; 排出构件，一部分显影剂通过该排出构件从储罐输送到排放开口，显影剂通过该排出口排出，排出口设置在排出构件中; 以及设置在排出构件的一部分内的反向流动产生螺钉，共享搅拌和输送螺杆的旋转轴中的一个，并推回显影剂的一部分，其中该部分具有缩径半径部分和横截面其中所述部分的半径与所述一个旋转轴的轴向垂直，所述半径部分的内半径比其余部分小，所述缩径部分位于所述部分的下部相对于该部分的垂直方向。

18. 发明授权

US07595481B2 Scanning optical system measuring device and scanning optical system measuring method 失效
标题翻译：扫描光学系统测量装置和扫描光学系统测量方法
公开(公告)号：US07595481B2
公开(公告)日：2009-09-29
申请号：US11840372
申请日：2007-08-17
申请人： Wataru Watanabe , Takahiro Chikuda
发明人： Wataru Watanabe , Takahiro Chikuda
IPC分类号： H01J3/14 , G02B7/04 , H04N1/04
CPC分类号： G01J1/4257 , G01J1/46 , G02B26/127 , H04N1/0473 , H04N1/1135 , H04N2201/04713 , H04N2201/04729 , H04N2201/04731 , H04N2201/04734 , H04N2201/04744
摘要： Measurement of a scanning optical system is to be carried out simply and easily. According to the invention, a scanning optical system measuring device for making adjustment of a scanning optical system which performs scanning with a light beam, includes: plural one-dimensional position detection devices provided at a distance from each other in a scanning direction of a light beam caused to perform scanning, and arranged to intersect the scanning direction of the light beam, and configured to output light receiving position of the light beam caused to perform scanning, as an analog signal; and a detection signal processing unit configured to detect scanning state of the light beam on the basis of a detection signal of the one-dimensional position detection devices.
摘要翻译：扫描光学系统的测量应简单而容易地进行。根据本发明，一种用于进行用光束进行扫描的扫描光学系统的调整的扫描光学系统测量装置包括：多个一维位置检测装置，其沿光的扫描方向彼此间隔设置光束进行扫描，并被布置为与光束的扫描方向相交，并且被配置为输出引起进行扫描的光束的光接收位置作为模拟信号; 以及检测信号处理单元，其被配置为基于所述一维位置检测装置的检测信号来检测所述光束的扫描状态。

19. 发明授权

US07531554B2 4-oxoquinoline compound and use thereof as HIV integrase inhibitor 有权
标题翻译： 4-氧代喹啉化合物及其作为HIV整合酶抑制剂的用途
公开(公告)号：US07531554B2
公开(公告)日：2009-05-12
申请号：US11133470
申请日：2005-05-20
申请人： Motohide Satoh , Takashi Matsuda , Satoshi Okuda , Hiroshi Kawakami , Hisateru Aramaki , Hisashi Shinkai , Yuji Matsuzaki , Wataru Watanabe , Kazunobu Yamataka , Shinichi Kiyonari , Shuichi Wamaki , Mitsuru Takahashi , Naohito Yamada , Akemi Nagao
发明人： Motohide Satoh , Takashi Matsuda , Satoshi Okuda , Hiroshi Kawakami , Hisateru Aramaki , Hisashi Shinkai , Yuji Matsuzaki , Wataru Watanabe , Kazunobu Yamataka , Shinichi Kiyonari , Shuichi Wamaki , Mitsuru Takahashi , Naohito Yamada , Akemi Nagao
IPC分类号： C07D215/04 , A61K31/44
CPC分类号： C07D215/56 , C07D401/04 , C07D401/06 , C07D405/06 , C07D491/04
摘要： Provision of a compound having an anti-HIV activity, particularly an integrase inhibitory activity.A 4-oxoquinoline compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof: wherein each symbol is as defined in the specification. The present invention also relates to a pharmaceutical composition containing the 4-oxoquinoline compound or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier; an integrase inhibitor, an antiviral agent, anti-HIV agent, and the like, which contains the 4-oxoquinoline compound or a pharmaceutically acceptable salt thereof as an active ingredient; an anti-HIV composition containing the 4-oxoquinoline compound or a pharmaceutically acceptable salt thereof, and one or more other kinds of anti-HIV activity substances as active ingredients; an anti-HIV agent containing the 4-oxoquinoline compound or a pharmaceutically acceptable salt thereof as an active ingredient, which is used for a multiple drug therapy with other anti-HIV agent(s), and the like.
摘要翻译：提供具有抗HIV活性的化合物，特别是整合酶抑制活性。由下式[I]表示的4-氧代喹啉化合物或其药学上可接受的盐：其中每个符号如说明书中所定义。本发明还涉及含有4-氧代喹啉化合物或其药学上可接受的盐和药学上可接受的载体的药物组合物; 含有4-氧代喹啉化合物或其药学上可接受的盐作为活性成分的整合酶抑制剂，抗病毒剂，抗HIV剂等; 含有4-氧代喹啉化合物或其药学上可接受的盐的抗HIV组合物和一种或多种其它类型的抗HIV活性物质作为活性成分; 含有4-氧代喹啉化合物或其药学上可接受的盐作为活性成分的抗HIV剂，其用于与其它抗HIV剂的多重药物治疗等。

20. 发明申请

US20080161311A1 Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor 审中-公开
标题翻译：含氮稠环化合物及其作为HIV整合酶抑制剂的用途
公开(公告)号：US20080161311A1
公开(公告)日：2008-07-03
申请号：US11783270
申请日：2007-04-06
申请人： Susumu Miyazaki , Susumu Katoh , Kaoru Adachi , Hirotaka Isoshima , Satoru Kobayashi , Yuji Matsuzaki , Wataru Watanabe , Kazunobu Yamataka , Shinichi Kiyonari , Shuichi Wamaki
发明人： Susumu Miyazaki , Susumu Katoh , Kaoru Adachi , Hirotaka Isoshima , Satoru Kobayashi , Yuji Matsuzaki , Wataru Watanabe , Kazunobu Yamataka , Shinichi Kiyonari , Shuichi Wamaki
IPC分类号： A61K31/519 , A61K31/503
CPC分类号： C07D471/04 , C07D487/04
摘要： The present invention relates to a nitrogen-containing fused ring compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof, and an anti-HIV agent containing such compound. The compound of the present invention has an HIV integrase inhibitory activity, and is useful as an agent for the prophylaxis or treatment of AIDS, or as an anti-HIV agent. In addition, by the combined use with other anti-HIV agents such as a protease inhibitor, a reverse transcriptase inhibitor and the like, it can be a more effective anti-HIV agent. Because it shows integrase-specific high inhibitory activity, the compound can be a pharmaceutical agent safe on human body, which causes only a fewer side effects.
摘要翻译：本发明涉及由下式[I]表示的含氮稠环化合物，其中每个符号如说明书中所定义，或其药学上可接受的盐和含有该化合物的抗HIV剂。本发明的化合物具有HIV整合酶抑制活性，可用作预防或治疗AIDS或作为抗HIV剂的药剂。此外，通过与其它抗HIV剂如蛋白酶抑制剂，逆转录酶抑制剂等的组合使用，它可以是更有效的抗HIV剂。因为它显示出整合酶特异性的高抑制活性，所以化合物可以是对人体安全的药剂，其副作用较小。

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