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11. 发明申请

US20110263999A1 METHOD AND APPARATUS FOR DETECTION OF NERVOUS SYSTEM DISORDERS 有权
标题翻译：检测神经系统疾病的方法和装置
公开(公告)号：US20110263999A1
公开(公告)日：2011-10-27
申请号：US13176890
申请日：2011-07-06
申请人： David L. Carlson , Eric J. Panken , Touby A. Drew , Jonathan C. Werder
发明人： David L. Carlson , Eric J. Panken , Touby A. Drew , Jonathan C. Werder
IPC分类号： A61B5/0476
CPC分类号： A61B5/02405 , A61B5/0456 , A61B5/0476 , A61B5/0482 , A61B5/4094 , A61B5/7221 , A61B5/7275 , A61N1/36082 , A61N2/006 , G06F19/00 , G06K9/00543
摘要： Systems and methods for detecting and/or treating nervous system disorders, such as seizures. Certain embodiments of the invention relate generally to implantable medical devices (IMDs) adapted to detect and treat nervous system disorders in patients with an IMD. Certain embodiments of the invention include detection of seizures based upon comparisons of long-term and short-term representations of physiological signals. Further embodiments of the invention include preparing for the delivery of therapy by warming up therapy delivery components prior to the expected delivery of therapy.
摘要翻译：用于检测和/或治疗神经系统疾病例如癫痫发作的系统和方法。本发明的某些实施方案一般涉及适于检测和治疗患有IMD的患者的神经系统疾病的可植入医疗装置（IMD）。本发明的某些实施方案包括基于生理信号的长期和短期表示的比较来检测癫痫发作。本发明的其它实施方案包括通过在治疗的预期递送之前预热治疗递送成分来准备递送治疗。

12. 发明授权

US08024029B2 Techniques for user-activated data retention in an implantable medical device 有权
标题翻译：在可植入医疗设备中用户激活的数据保留技术
公开(公告)号：US08024029B2
公开(公告)日：2011-09-20
申请号：US11264915
申请日：2005-11-02
申请人： Touby A. Drew , Jonathon E. Giftakis , Nina M. Graves , Jonathan C. Werder , David L. Carlson
发明人： Touby A. Drew , Jonathon E. Giftakis , Nina M. Graves , Jonathan C. Werder , David L. Carlson
IPC分类号： A61B5/04 , A61N1/00
CPC分类号： A61B5/0031 , A61B5/04325 , A61B5/0476 , A61B5/113 , A61B5/4094 , A61B5/7232 , A61N1/36082 , A61N1/3702 , A61N1/37252 , G06F19/00 , G06F19/3481 , G16H40/63
摘要： Apparatus for storing data records associated with a medical monitoring event in a data structure. Upon indication by a patient of a possible manifestation of a neurological event, the implanted device obtains and stores data in the data record in a first data structure that is age-based. Before an oldest data record is lost, the oldest data record may be stored in a second data structure that is priority index-based. The priority index may be determined by a severity level and may be further determined by associated factors. The implanted device may organize, off-load, report, and/or display a plurality of data records based on an associated priority index. Additionally, the implanted device may select a subset or composite of physiologic channels from the available physiologic channels based on a selection criterion.
摘要翻译：用于存储与数据结构中的医疗监视事件相关联的数据记录的装置。在由患者指示神经系统事件的可能表现的情况下，植入装置以数据记录的形式获取并存储数据为基于年龄的第一数据结构。在最旧的数据记录丢失之前，最早的数据记录可以存储在基于优先级索引的第二数据结构中。优先权索引可以由严重性级别确定，并且可以由相关因素进一步确定。植入的装置可以基于相关联的优先级索引来组织，卸载，报告和/或显示多个数据记录。另外，植入装置可以基于选择标准从可用生理通道中选择生理通道的子集或复合物。

13. 发明申请

US20110172564A1 USER INTERFACE THAT DISPLAYS MEDICAL THERAPY AND POSTURE DATA 有权
标题翻译：用户界面显示医疗和姿势数据
公开(公告)号：US20110172564A1
公开(公告)日：2011-07-14
申请号：US12985127
申请日：2011-01-05
申请人： Touby A. Drew
发明人： Touby A. Drew
IPC分类号： A61N1/08 , A61N1/36 , A61B5/103
CPC分类号： A61B5/1116 , A61B5/061 , A61B5/1118 , A61B5/4824 , A61B5/686 , A61B2560/0219 , A61B2562/0219 , A61N1/36071 , A61N1/37247 , G06F19/00 , G06F19/3481 , G16H40/63
摘要： The disclosure relates to a system that displays posture state information, physiological conditions of a patient on an avatar or other graphical representation of a human body, and therapy parameter information to facilitate the programming of therapy that is delivered to a patient. In some examples, the system may include an implantable medical device (IMD) that delivers therapy to a patient and incorporates a posture state module that detects a posture state engaged by the patient to determine the therapy delivered to the patient. An external programming device may communicate with the IMD, e.g., in real-time, to display the posture state of the patient as well as therapy parameters and physiological conditions associated with the posture state of the patient. The external programming device may receive adjustment input from the clinician to adjust one or more therapy parameters for therapy delivered to a patient in a specific posture state. In some examples, the external programming device may retrieve therapy information from the IMD to allow the clinician to review and play back previously stored therapy information on a temporal basis.
摘要翻译：本公开涉及一种系统，其显示姿势状态信息，患者在化身上的生理状况或人体的其他图形表示，以及治疗参数信息，以便于编程传递给患者的治疗。在一些示例中，系统可以包括将治疗递送给患者的可植入医疗装置（IMD），并且包括检测由患者接合的姿势状态以确定递送给患者的治疗的姿势状态模块。外部程序设备可以例如实时地与IMD通信，以显示患者的姿势状态以及与患者的姿势状态相关联的治疗参数和生理状态。外部编程装置可以接收来自临床医生的调整输入，以调整用于在特定姿势状态下递送给患者的治疗的一个或多个治疗参数。在一些示例中，外部编程设备可以从IMD获取治疗信息，以允许临床医生在时间基础上审查和回放先前存储的治疗信息。

14. 发明授权

US07764988B2 Flexible memory management scheme for loop recording in an implantable device 有权
标题翻译：灵活的存储器管理方案，用于可植入设备中的循环记录
公开(公告)号：US07764988B2
公开(公告)日：2010-07-27
申请号：US11380590
申请日：2006-04-27
申请人： Touby A. Drew , David L. Carlson
发明人： Touby A. Drew , David L. Carlson
IPC分类号： A61B5/0432
CPC分类号： A61B5/0476 , A61B5/4094 , A61B5/7232
摘要： A method and apparatus is provided for handling multiple recordings that result from events in a limited memory device. The events may include various automatic and manual triggers. The method provides a mechanism for storing different configurations of data, associated with different events.
摘要翻译：提供一种用于处理由有限存储器件中的事件引起的多个记录的方法和装置。事件可能包括各种自动和手动触发。该方法提供用于存储与不同事件相关联的数据的不同配置的机制。

15. 发明申请

US20070249956A1 METHOD AND APPARATUS FOR DETECTION OF NERVOUS SYSTEM DISORDERS 审中-公开
公开(公告)号：US20070249956A1
公开(公告)日：2007-10-25
申请号：US11609540
申请日：2006-12-12
申请人： David L. Carlson , Eric J. Panken , Touby A. Drew , Jonathan C. Werder
发明人： David L. Carlson , Eric J. Panken , Touby A. Drew , Jonathan C. Werder
IPC分类号： A61B5/04
CPC分类号： A61B5/048 , A61B5/4094 , A61B5/7275 , A61N1/08 , G16H40/63 , G16H50/20
摘要： Systems and methods for detecting and/or treating nervous system disorders, such as seizures, are disclosed. Certain embodiments of the invention relate generally to implantable medical devices (IMDs) adapted to detect and treat nervous system disorders in patients with an IMD. Certain embodiments of the invention include detection of seizures based upon comparisons of long-term and short-term representations of physiological signals. Other embodiments include prediction of seizure activity based upon analysis of physiological signal levels. An embodiment of the invention monitors the quality of physiological signals, and may be able to compensate for signals of low signal quality. A further embodiment of the invention includes detection of seizure activity following the delivery of therapy.

16. 发明授权

US09996669B2 Intelligent discovery of medical devices by a programming system 有权
公开(公告)号：US09996669B2
公开(公告)日：2018-06-12
申请号：US11800423
申请日：2007-05-04
申请人： Steven M. Goetz , Touby A. Drew , Earle T. Roberts
发明人： Steven M. Goetz , Touby A. Drew , Earle T. Roberts
IPC分类号： A61N1/00 , G06F19/00 , A61N1/372
CPC分类号： G16H40/67 , A61N1/37288 , G06F19/00 , G06F19/3418 , G16H40/20 , G16H40/40
摘要： Techniques for automatically identifying medical devices, e.g., implantable medical device, using wireless communications in order to communicate with the medical devices are described. For instance, a programming system securely discovers a set of medical devices which have the capacity to communicate using wireless communication links. The programming system may then apply one or more search heuristics to identify a set of discovered medical devices that are likely to be a medical device with which a user desires to interact. When the user selects the desired one of the identified medical devices, the programming system launches a device interaction application associated with the desired medical device. The user may use the device interaction application to interact with the desired medical device.

17. 发明授权

US09357949B2 User interface that displays medical therapy and posture data 有权
标题翻译：显示医疗和姿势数据的用户界面
公开(公告)号：US09357949B2
公开(公告)日：2016-06-07
申请号：US12985127
申请日：2011-01-05
申请人： Touby A. Drew
发明人： Touby A. Drew
IPC分类号： A61N1/36 , A61B5/11 , A61B5/06 , A61B5/00 , G06F19/00 , A61N1/372
CPC分类号： A61B5/1116 , A61B5/061 , A61B5/1118 , A61B5/4824 , A61B5/686 , A61B2560/0219 , A61B2562/0219 , A61N1/36071 , A61N1/37247 , G06F19/00 , G06F19/3481 , G16H40/63
摘要： The disclosure relates to a system that displays posture state information, physiological conditions of a patient on an avatar or other graphical representation of a human body, and therapy parameter information to facilitate the programming of therapy that is delivered to a patient. In some examples, the system may include an implantable medical device (IMD) that delivers therapy to a patient and incorporates a posture state module that detects a posture state engaged by the patient to determine the therapy delivered to the patient. An external programming device may communicate with the IMD, e.g., in real-time, to display the posture state of the patient as well as therapy parameters and physiological conditions associated with the posture state of the patient. The external programming device may receive adjustment input from the clinician to adjust one or more therapy parameters for therapy delivered to a patient in a specific posture state. In some examples, the external programming device may retrieve therapy information from the IMD to allow the clinician to review and play back previously stored therapy information on a temporal basis.
摘要翻译：本公开涉及一种系统，其显示姿势状态信息，患者在化身上的生理状况或人体的其他图形表示，以及治疗参数信息，以便于编程传递给患者的治疗。在一些示例中，系统可以包括将治疗递送给患者的可植入医疗装置（IMD），并且包括检测由患者接合的姿势状态以确定递送给患者的治疗的姿势状态模块。外部程序设备可以例如实时地与IMD通信，以显示患者的姿势状态以及与患者的姿势状态相关联的治疗参数和生理状态。外部编程装置可以接收来自临床医生的调整输入，以调整用于在特定姿势状态下递送给患者的治疗的一个或多个治疗参数。在一些示例中，外部编程设备可以从IMD获取治疗信息，以允许临床医生在时间基础上审查和回放先前存储的治疗信息。

18. 发明授权

US09122785B2 Display of supplemental bolus in relation to programmed dose 有权
标题翻译：显示相对于程序剂量的补充推注
公开(公告)号：US09122785B2
公开(公告)日：2015-09-01
申请号：US12691513
申请日：2010-01-21
申请人： Sarah B. Alme , Touby A. Drew , Lance Beall
发明人： Sarah B. Alme , Touby A. Drew , Lance Beall
IPC分类号： G06T11/20 , G06F19/00 , A61M5/142 , A61B19/00
CPC分类号： G06F19/3468 , A61B34/25 , A61M5/14276 , G06F19/00
摘要： Techniques are described for displaying a representation of a supplemental bolus and a representation of programmed doses of a therapy schedule for an implantable fluid delivery device with a programmer device. In one example, a device includes a user interface to present a graphical representation of doses of fluid to be delivered to a patient via an implantable fluid delivery device and a processor that controls the user interface to simultaneously present a first graphical representation of a supplemental bolus to be delivered by the implantable fluid delivery device and a second graphical representation of programmed doses of a therapy schedule of the implantable fluid delivery device, wherein at least a portion of the programmed doses of the therapy schedule follows delivery of the supplemental bolus by the implantable fluid delivery device. A user of the device may determine whether the representations indicate an excessive dosage risk to the patient.
摘要翻译：描述了用于显示补充弹丸的表示的技术以及用于具有编程器装置的可植入流体输送装置的治疗计划的程序剂量的表示。在一个示例中，设备包括用户界面，用于呈现待经由可植入流体输送装置递送至患者的流体的剂量的图形表示，以及控制用户界面以同时呈现补充弹丸的第一图形表示的处理器由可植入流体递送装置递送，以及编程剂量的可植入流体输送装置的治疗计划的第二图形表示，其中治疗计划的程序剂量的至少一部分随后通过可植入的药物递送流体输送装置。设备的用户可以确定表示是否表示对患者的过度剂量风险。

19. 发明授权

US08862451B2 User interface indicating fluid location for an implantable fluid delivery device 有权
标题翻译：指示可植入流体输送装置的流体位置的用户界面
公开(公告)号：US08862451B2
公开(公告)日：2014-10-14
申请号：US12691574
申请日：2010-01-21
申请人： Sarah B. Alme , Touby A. Drew , Jiaying Shen
发明人： Sarah B. Alme , Touby A. Drew , Jiaying Shen
IPC分类号： G06G7/58 , G06G7/48 , A61M5/142 , G09B23/28 , G06F19/00
CPC分类号： A61M5/14276 , A61M2005/14288 , A61M2205/3507 , A61M2205/502 , G06F19/00 , G06F19/3468 , G09B23/285 , G16H50/50
摘要： A programmer device includes an interface that communicates with an implantable fluid delivery device and a user interface that displays a representation of a portion of the implantable fluid delivery device and displays an indication of a location of fluid within the implantable fluid delivery device during a delivery phase, e.g., a priming or bridging phase. The user interface may display a representation of progress of the delivery phase. The user interface may display the indication of the location of the fluid within internal tubing of the implantable fluid delivery device or within a catheter of the implantable fluid delivery device. The programmer device may display the representation of the progress of the delivery phase as a simulation of the delivery phase or during the actual delivery phase of the implantable fluid delivery device. A user may therefore observe a location of fluid corresponding to progress of the delivery phase.
摘要翻译：编程器装置包括与可植入流体输送装置通信的界面和显示可植入流体输送装置的一部分的表示的用户界面，并且在输送阶段期间显示流体在可植入流体输送装置内的位置的指示例如，起动或桥接阶段。用户界面可以显示递送阶段的进展的表示。用户界面可以显示流体在可植入流体输送装置的内部管道内或者在可植入流体输送装置的导管内的位置的指示。编程器装置可以将输送阶段的进展的表示显示为递送阶段的模拟或在可植入流体输送装置的实际输送阶段期间。因此，用户可以观察对应于递送阶段的进展的流体的位置。

20. 发明授权

US08565864B2 Techniques for data retention upon detection of an event in an implantable medical device 有权
标题翻译：检测植入式医疗设备中的事件时的数据保留技术
公开(公告)号：US08565864B2
公开(公告)日：2013-10-22
申请号：US13349404
申请日：2012-01-12
申请人： Touby A. Drew , Jonathon E. Giftakis , David L. Carlson , Eric J. Panken , Jonathan C. Werder , Nina M. Graves
发明人： Touby A. Drew , Jonathon E. Giftakis , David L. Carlson , Eric J. Panken , Jonathan C. Werder , Nina M. Graves
IPC分类号： A61B5/04
CPC分类号： A61B5/4094 , A61B5/0006 , A61B5/0031 , A61B5/02055 , A61B5/021 , A61B5/024 , A61B5/031 , A61B5/04001 , A61B5/04012 , A61B5/0402 , A61B5/0476 , A61B5/0816 , A61B5/1118 , A61B5/165 , A61B5/4082 , A61B5/686 , A61B5/7232 , A61B5/7282 , A61N1/36132 , A61N1/36135 , A61N1/36521 , A61N1/36585 , A61N1/3702 , A61N1/37252 , A61N1/37282 , G06F17/30336 , G06F19/00 , G06F19/3418 , G16H10/60 , G16H40/63
摘要： Methods and apparatus for storing data records associated with a medical monitoring event in a data structure. These include initiating loop recording in an implantable medical device upon determination of a neurological event, wherein loop recording comprises storing a data record of a plurality of data records in a data structure, the plurality of data records representing information about determined neurological events. Methods and apparatus can further include determining a priority index for the plurality of data records based on severity levels of the determined neurological events and replacing older data records of the plurality of data records on the data structure with new data records according to the priority index, wherein the new data records selectively replace those data records in the data structure having the lowest associated priority index.
摘要翻译：用于存储与数据结构中的医疗监视事件相关联的数据记录的方法和装置。这些包括在确定神经学事件时在可植入医疗装置中启动循环记录，其中循环记录包括将多个数据记录的数据记录存储在数据结构中，所述多个数据记录表示关于确定的神经系统事件的信息。方法和装置还可以包括基于所确定的神经病学事件的严重性水平确定多个数据记录的优先级索引，并根据优先级索引用新的数据记录替换数据结构上的多个数据记录的较旧的数据记录，其中新数据记录选择性地替换具有最低相关优先级索引的数据结构中的那些数据记录。

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