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11. 发明授权

US08424741B2 Apparatus and method for resectioning gastro-esophageal tissue 有权
公开(公告)号：US08424741B2
公开(公告)日：2013-04-23
申请号：US11471126
申请日：2006-06-20
申请人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
发明人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
IPC分类号： A61B17/068
CPC分类号： A61B17/105 , A61B1/2736 , A61B17/00234 , A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/3205 , A61B2017/00278 , A61B2017/00827 , A61B2017/07214 , A61B2017/07221 , A61B2017/2905 , A61B2017/2923
摘要： A system for stapling tissue comprises a flexible endoscope and an operative head including a pair of opposed, curved tissue clamping jaws sized to pass through an esophagus, the jaws being moveable with respect to one another between an open tissue receiving configuration and a closed tissue clamping configuration, a first one of the curved jaws including a stapling mechanism and a second one of the jaws including a staple forming anvil surface, the stapling mechanism including staple slots through which staples are fired arranged in a row extending from a proximal end of the first jaw to a distal end thereof in combination with a control handle which, when the operative head is in an operative position within one of a patient's stomach and esophagus, remains outside the patient, the control handle including a first actuator for moving the jaws relative to one another and a second actuator for operating the stapling mechanism.

12. 发明授权

US07799014B2 Dialysis catheter 有权
标题翻译：透析导管
公开(公告)号：US07799014B2
公开(公告)日：2010-09-21
申请号：US10924076
申请日：2004-08-23
申请人： James F. McGuckin, Jr. , Paul Tashjian , Michael W. Paris , Peter W. J. Hinchliffe
发明人： James F. McGuckin, Jr. , Paul Tashjian , Michael W. Paris , Peter W. J. Hinchliffe
IPC分类号： A61M25/00
CPC分类号： A61M25/04 , A61M1/285 , A61M1/3661 , A61M25/0028 , A61M25/0029 , A61M25/0032 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0071 , A61M25/0074 , A61M25/008 , A61M25/0102 , A61M25/0194 , A61M25/09041 , A61M2025/0031 , A61M2025/0036 , A61M2025/0081
摘要： A dialysis catheter comprising a catheter body having a proximal portion, a distal portion, a first longitudinally extending central lumen configured to deliver blood, and at least three longitudinally extending lumens positioned radially of the central lumen and configured to withdraw blood from a patient. At least one blood delivery opening is formed in the distal portion of the catheter body and in fluid communication with the first lumen and configured for passage of blood therethrough. At least three blood withdrawal openings are formed in the outer wall of the catheter body, wherein each of the openings is in fluid communication with one of the at least three lumens and is configured for passage of blood from a patient.
摘要翻译：一种透析导管，其包括具有近端部分的远端部分，远端部分，构造成输送血液的第一纵向延伸的中心腔和至少三个纵向延伸的腔，所述导管主体位于所述中心腔的径向位置并且被配置为从患者抽出血液。至少一个血液输送开口形成在导管主体的远端部分中并且与第一腔流体连通并且构造成使血液通过其中。在导管主体的外壁中形成至少三个抽血开口，其中每个开口与至少三个流明中的一个流体连通，并且构造成用于从患者通过血液。

13. 发明授权

US07011645B2 Dialysis catheter 有权
公开(公告)号：US07011645B2
公开(公告)日：2006-03-14
申请号：US10279466
申请日：2002-10-24
申请人： James F. McGuckin, Jr. , Michael W. Paris , Paul Tashjian , Peter W. J. Hinchliffe
发明人： James F. McGuckin, Jr. , Michael W. Paris , Paul Tashjian , Peter W. J. Hinchliffe
IPC分类号： A61M1/00 , A61M5/00 , A61M25/00
CPC分类号： A61M1/285 , A61M1/3661 , A61M25/001 , A61M25/0028 , A61M25/0029 , A61M25/0032 , A61M25/0068 , A61M25/007 , A61M25/0071 , A61M25/008 , A61M25/0097 , A61M25/04 , A61M25/0668 , A61M25/09041 , A61M2025/0006 , A61M2025/0031 , A61M2025/0034 , A61M2025/0036 , A61M2025/0081 , A61M2025/0286 , A61M2025/09125
摘要： A catheter for delivering and withdrawing blood from a patient's body comprising a catheter body having a distal portion, a central return lumen extending from a proximal portion of the catheter body to the distal portion to allow blood passage therethrough, at least three longitudinally extending intake lumens independent of the return lumen and radially displaced with respect to the return lumen, and means for enabling simultaneous cut off of fluid flow to the at least three longitudinally extending lumens.

14. 发明授权

US06986752B2 Peritoneal dialysis catheter and insertion method 失效
公开(公告)号：US06986752B2
公开(公告)日：2006-01-17
申请号：US10057022
申请日：2002-01-25
申请人： James F. McGuckin, Jr. , Paul Tashjian , Peter W. J. Hinchliffe
发明人： James F. McGuckin, Jr. , Paul Tashjian , Peter W. J. Hinchliffe
IPC分类号： A61M1/00
CPC分类号： A61M1/285 , A61M25/09041
摘要： A peritoneal dialysis catheter for insertion into the abdominal cavity of a patient for delivering and withdrawing fluid from a patient comprising a catheter body having a proximal portion, a distal tip portion and a first longitudinally extending lumen configured to deliver fluid into the abdominal cavity. First and second side openings are formed in an outer wall of the catheter body adjacent the distal tip portion and are in fluid communication with the first lumen and configured for passage of fluid therethrough. A stiffening insert is positioned in the distal tip portion and has a first stiffness greater than a second stiffness of the distal tip portion to facilitate entry into the abdominal cavity. The stiffening insert has a lumen therethrough communicating with the first lumen. A method for insertion of the dialysis catheter is also disclosed.

15. 发明授权

US06949107B2 Injection method for locating vessel lumen 有权
标题翻译：用于定位血管腔的注射方法
公开(公告)号：US06949107B2
公开(公告)日：2005-09-27
申请号：US10609027
申请日：2003-06-27
申请人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe , Richard T. Briganti , Walter H. Peters
发明人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe , Richard T. Briganti , Walter H. Peters
IPC分类号： A61B17/00 , A61B17/064 , A61B17/10 , A61M5/178
CPC分类号： A61B17/0057 , A61B17/064 , A61B2017/00637 , A61B2017/00659 , A61B2017/00867
摘要： A method of locating a vessel lumen to enable placement of a vascular hole closure device comprising the steps of providing a syringe containing a fluid therein, connecting the syringe to an elongated instrument, exerting a force on the syringe plunger as it is inserted through the tissue towards the vessel wall, and detecting movement of the syringe to eject the fluid to determine entry of the elongated instrument into the vessel lumen.
摘要翻译：一种定位血管腔以能够放置血管孔闭合装置的方法，包括以下步骤：在其中提供含有流体的注射器，将注射器连接到细长的器械，当注射器柱塞插入穿过组织时施加力并且检测注射器的运动以喷射流体以确定细长器械进入血管内腔。

16. 发明授权

US06890349B2 Covered stent with side branch 有权
标题翻译：带侧支的支架
公开(公告)号：US06890349B2
公开(公告)日：2005-05-10
申请号：US09973365
申请日：2001-10-09
申请人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
发明人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
IPC分类号： A61F2/06 , A61F2/82 , A61F2/88 , A61F2/90
CPC分类号： A61F2/07 , A61F2/856 , A61F2/88 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/954 , A61F2002/061 , A61F2002/065 , A61F2002/067 , A61F2002/072 , A61F2002/075 , A61F2002/821 , A61F2210/0076 , A61F2230/0008 , A61F2230/001 , A61F2230/0013 , A61F2230/0054
摘要： A system for treating stenosis in a target blood vessel, such as the common carotid artery, comprising a graft portion having a main portion and a branch portion extending therefrom. The branch portion extends from the intermediate portion of the main portion at an angle thereto and is in fluid communication with the main portion. A first stent is associated with the main portion and is expandable from a first configuration to a second configuration to retain the main portion in position within the target vessel. A second stent is associated with the branch portion and is expandable from a first configuration to a second configuration to retain the branch portion in position within a branching vessel. In one embodiment, the branch portion is integral with the main portion. In an alternate embodiment the branch portion is connected to the main portion.
摘要翻译：一种用于治疗目标血管（例如颈总动脉）中的狭窄的系统，包括具有主要部分和从其延伸的分支部分的移植部分。分支部分从主体部分的中间部分以一定角度延伸并且与主要部分流体连通。第一支架与主要部分相关联并且可从第一构造扩展到第二构造，以将主要部分保持在目标容器内的适当位置。第二支架与分支部分相关联并且可从第一构造扩展到第二构造，以将分支部分保持在分支容器内的适当位置。在一个实施例中，分支部分与主要部分是一体的。在替代实施例中，分支部分连接到主要部分。

17. 发明授权

US06835199B2 Apparatus and method for resectioning gastro-esophageal tissue 有权
标题翻译：用于切除胃食管组织的装置和方法
公开(公告)号：US06835199B2
公开(公告)日：2004-12-28
申请号：US10062760
申请日：2002-01-31
申请人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
发明人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
IPC分类号： A61B17068
CPC分类号： A61B17/105 , A61B1/2736 , A61B17/00234 , A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/3205 , A61B2017/00278 , A61B2017/00827 , A61B2017/07214 , A61B2017/07221 , A61B2017/2905 , A61B2017/2923
摘要： A system for stapling tissue comprises a flexible endoscope and an operative head including a pair of opposed, curved tissue clamping jaws sized to pass through an esophagus, the jaws being moveable with respect to one another between an open tissue receiving configuration and a closed tissue clamping configuration, a first one of the curved jaws including a stapling mechanism and a second one of the jaws including a staple forming anvil surface, the stapling mechanism including staple slots through which staples are fired arranged in a row extending from a proximal end of the first jaw to a distal end thereof in combination with a control handle which, when the operative head is in an operative position within one of a patient's stomach and esophagus, remains outside the patient, the control handle including a first actuator for moving the jaws relative to one another and a second actuator for operating the stapling mechanism.
摘要翻译：用于缝合组织的系统包括柔性内窥镜和操作头部，其包括一对相对的弯曲的组织夹紧爪，其尺寸设置成穿过食道，钳口可在打开的组织接收构型和封闭组织夹紧之间相对于彼此移动所述弯曲夹爪中的第一个包括装订机构和包括钉子形成砧座表面的第二夹爪，所述缝合机构包括订书钉狭槽，所述订书钉槽从所述第一与控制手柄组合的钳口与控制柄相结合，当操作头处于患者胃和食道之一内的操作位置时，控制手柄保持在患者外部，控制手柄包括第一致动器，用于相对于手柄移动钳口彼此和用于操作装订机构的第二致动器。

18. 发明授权

US08167935B2 Percutaneous aortic valve 有权
标题翻译：经皮主动脉瓣
公开(公告)号：US08167935B2
公开(公告)日：2012-05-01
申请号：US12880456
申请日：2010-09-13
申请人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
发明人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61B2017/00243 , A61F2/2421 , A61F2/2436 , A61F2230/0091 , Y10S623/904
摘要： The present invention provides a valve configured for insertion on the proximal and distal sides of a heart valve annulus to replace the heart valve of a patient. The valve comprises a first substantially annular portion adapted to be positioned on a proximal side of the annulus of a patient and a second substantially annular portion adapted to be positioned on a distal side of the annulus of a patient, wherein at least one of the first and second substantially annular portions is movable towards the other portion to a clamped position to clamp around the annulus. The second portion has a flow restricting portion extending therefrom and is movable between a first position to permit the flow of blood and a second position to restrict the flow of blood. In one embodiment, the valve has a suture joining the first and second portions to draw the first and second portions into closer proximity and a cinch member to secure the suture to maintain the first and second portions in the clamped position. In another embodiment, the first and second portions are connected by a first segment which biases the first and second portions toward the clamped position.
摘要翻译：本发明提供一种构造成用于插入心脏瓣膜环的近侧和远侧以更换患者的心脏瓣膜的阀。阀包括适于定位在患者的环空的近侧上的第一基本上环形的部分和适于定位在患者的环的远端侧的第二基本上环形的部分，其中，第一并且第二基本环形部分可朝向另一部分移动到夹紧位置以夹紧环形。第二部分具有从其延伸的流动限制部分，并且可在第一位置之间移动以允许血液流动，以及第二位置以限制血液流动。在一个实施例中，阀具有连接第一和第二部分以将第一和第二部分拉近更靠近的缝合线，以及紧固构件以固定缝线以将第一和第二部分保持在夹紧位置。在另一个实施例中，第一和第二部分通过将第一和第二部分朝向夹紧位置偏压的第一部分连接。

19. 发明授权

US07445632B2 Percutaneous aortic valve 有权
标题翻译：经皮主动脉瓣
公开(公告)号：US07445632B2
公开(公告)日：2008-11-04
申请号：US11222570
申请日：2005-09-09
申请人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
发明人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61B2017/00243 , A61F2/2421 , A61F2/2436 , A61F2230/0091 , Y10S623/904
摘要： The present invention provides a valve configured for insertion on the proximal and distal sides of a heart valve annulus to replace the heart valve of a patient. The valve comprises a first substantially annular portion adapted to be positioned on a proximal side of the annulus of a patient and a second substantially annular portion adapted to be positioned on a distal side of the annulus of a patient, wherein at least one of the first and second substantially annular portions is movable towards the other portion to a clamped position to clamp around the annulus. The second portion has a flow restricting portion extending therefrom and is movable between a first position to permit the flow of blood and a second position to restrict the flow of blood. In one embodiment, the valve has a suture joining the first and second portions to draw the first and second portions into closer proximity and a cinch member to secure the suture to maintain the first and second portions in the clamped position. In another embodiment, the first and second portions are connected by a first segment which biases the first and second portions toward the clamped position.
摘要翻译：本发明提供一种构造成用于插入心脏瓣膜环的近侧和远侧以更换患者的心脏瓣膜的阀。阀包括适于定位在患者的环空的近侧上的第一基本上环形的部分和适于定位在患者的环的远侧的第二基本上环形的部分，其中，第一并且第二基本环形部分可朝向另一部分移动到夹紧位置以夹紧环形。第二部分具有从其延伸的流动限制部分，并且可在第一位置之间移动以允许血液流动，以及第二位置以限制血液流动。在一个实施例中，阀具有连接第一和第二部分以将第一和第二部分拉近更靠近的缝合线，以及紧固构件以固定缝线以将第一和第二部分保持在夹紧位置。在另一个实施例中，第一和第二部分通过将第一和第二部分朝向夹紧位置偏压的第一部分连接。

20. 发明授权

US06908477B2 Methods of implanting covered stents with side branch 有权
标题翻译：用侧支植入覆盖支架的方法
公开(公告)号：US06908477B2
公开(公告)日：2005-06-21
申请号：US09973450
申请日：2001-10-09
申请人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
发明人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
IPC分类号： A61F2/06 , A61F2/82 , A61F2/88 , A61F2/90
CPC分类号： A61F2/07 , A61F2/856 , A61F2/88 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/954 , A61F2002/061 , A61F2002/065 , A61F2002/067 , A61F2002/072 , A61F2002/075 , A61F2002/821 , A61F2210/0076 , A61F2230/0008 , A61F2230/001 , A61F2230/0013 , A61F2230/0054
摘要： A method of implanting first and second stents with associated grafts within first and second vessel regions extending at an angle with respect to each other comprising inserting a first guidewire to guide a first stent with an associated first graft to the first vessel region, inserting a second guidewire to guide a second stent with an associated second graft to the second vessel region, inserting first and second delivery sheaths containing the first and second stent with the associated grafts over the first and second guidewires and removing the first and second delivery sheaths to enable the first and second stents with the associated grafts to expand against the wall of the first and second vessel regions, respectively. A delivery system is also disclosed.
摘要翻译：在相对于彼此以一定角度延伸的第一和第二血管区域内植入具有相关移植物的第一和第二支架的方法包括插入第一导丝以将具有相关联的第一移植物的第一支架引导到第一血管区域，引导线将具有相关联的第二移植物的第二支架引导到第二血管区域，将包含第一和第二支架的第一和第二输送护套与相关联的移植物插入在第一和第二导丝上，并且移除第一和第二输送护套，第一和第二支架，其中相关联的移植物分别与第一和第二血管区域的壁膨胀。还公开了传送系统。

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