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11. 发明授权

US08532790B2 Slidable fixation device for securing a medical implant 有权
标题翻译：用于固定医疗植入物的可滑动固定装置
公开(公告)号：US08532790B2
公开(公告)日：2013-09-10
申请号：US12759173
申请日：2010-04-13
申请人： Erik Griswold
发明人： Erik Griswold
IPC分类号： A61N1/00
CPC分类号： A61N1/3756 , A61B17/3468 , A61N1/057 , A61N1/37205 , A61N1/37518
摘要： A fixation device for retaining a leadless medical implant to tissue includes an annular collar and an array of self-expanding tines extending from the collar. When deployed, the annular collar encircles the implant and the tines are preset to splay outwardly from the implant to grab body tissue and anchor the implant at a treatment site. The implant and fixation device are contained within a sheath for delivery to the treatment site and a pushing force is applied to a pusher of the delivery system to distally advance the fixation device relative to the implant and deploy the tines. A distal end of the implant having an electrode may form a distal tip of the delivery system, and a potential implantation site may be tested prior to deployment of the fixation device to allow for easy repositioning of the implant if the potential implantation site is determined to be unacceptable.
摘要翻译：用于将无引线医用植入物保持在组织上的固定装置包括环形环和从套环延伸的自膨胀齿的阵列。当部署时，环形套环环绕植入物，并且预定齿从植入物向外张开以抓住身体组织并将植入物锚固在治疗部位。植入物和固定装置包含在护套内用于输送到治疗部位，并且将推力施加到输送系统的推动器以相对于植入物远端地推进固定装置并且部署尖齿。具有电极的植入物的远端可以形成递送系统的远端，并且可以在部署固定装置之前测试潜在的植入部位，以便如果将潜在的植入部位确定为不可接受

12. 发明授权

US08478431B2 Slidable fixation device for securing a medical implant 有权
标题翻译：用于固定医疗植入物的可滑动固定装置
公开(公告)号：US08478431B2
公开(公告)日：2013-07-02
申请号：US13047456
申请日：2011-03-14
申请人： Erik Griswold , James Calvin Allan , Don Tran
发明人： Erik Griswold , James Calvin Allan , Don Tran
IPC分类号： A61N1/00
CPC分类号： A61N1/37205 , A61B17/3468 , A61N1/0573 , A61N1/362 , A61N1/3756 , A61N2001/083
摘要： A fixation device for retaining a leadless medical implant to tissue includes an array of elongate tines having self-expanding distal portions. The fixation tines may be advanced between an implant body and an outer jacket to deploy the tines from a delivery configuration in which the tines are constrained by the outer jacket to an expanded configuration in which the distal end portions of the tines are released from the outer jacket. The implant and fixation device are contained within a sheath for delivery to the treatment site and a pusher within the sheath advances the fixation device relative to the implant body and deploys the tines. A distal end of the implant having an electrode may form a distal tip of the delivery system, and a potential implantation site may be tested prior to deployment of the fixation device to allow for easy repositioning of the implant.
摘要翻译：用于将无引线医用植入物保持在组织上的固定装置包括具有自扩张远侧部分的细长尖齿阵列。固定齿可以在植入物主体和外护套之间前进，以将齿从其中齿由外护套约束的输送构型展开到扩张构型，其中尖齿的远端部分从外部释放夹克。植入物和固定装置包含在护套内用于输送到治疗部位，并且护套内的推动器相对于植入体前进固定装置并且展开齿。具有电极的植入物的远端可以形成递送系统的远侧末端，并且可以在展开固定装置之前测试潜在的植入部位，以便容易地重新定位植入物。

13. 发明授权

US08465436B2 Endoluminal implant with locking and centering fixation system 有权
标题翻译：具有锁定和定心固定系统的腔内植入物
公开(公告)号：US08465436B2
公开(公告)日：2013-06-18
申请号：US12768235
申请日：2010-04-27
申请人： Erik Griswold
发明人： Erik Griswold
IPC分类号： A61B5/021 , A61F2/90 , A61F2/82 , A61F2/88
CPC分类号： A61B5/02152 , A61B5/0031 , A61B5/6862 , A61F2/82 , A61F2/962 , A61F2250/0002
摘要： An implant centering system includes a sensor connected to a hollow cylindrical anchor via at least two struts. The hollow cylindrical anchor is transformable between a radially compressed configuration for delivery and a radially expanded configuration for lodging against a vessel wall. The struts longitudinally relocate the sensor between a first position in which the sensor is longitudinally spaced apart from the radially compressed anchor, and a second position in which the sensor is at least partially within a lumen of the radially expanded anchor and radially centered within vessel. In one embodiment, the struts are heat-set into a curved configuration and an externally applied force longitudinally relocates the sensor until the struts lock over center into their heat-set configuration. In another embodiment, radial expansion of the anchor longitudinally relocates the sensor without an externally applied force.
摘要翻译：植入物定心系统包括经由至少两个支柱连接到中空圆柱形锚固件的传感器。中空圆柱形锚固件可在用于输送的径向压缩构造和用于抵靠血管壁的径向扩张构型之间变形。支柱纵向地将传感器重新定位在传感器与径向压缩的锚固件纵向间隔开的第一位置和第二位置，在第二位置，传感器至少部分地位于径向膨胀的锚固体的内腔中并且在容器内径向居中。在一个实施例中，支柱被热定形成弯曲构型，并且外部施加的力纵向地重新定位传感器，直到支柱锁定在其中心为其热定形构造。在另一个实施例中，锚的径向膨胀纵向地重新定位传感器而没有外部施加的力。

14. 发明申请

US20130131591A1 DELIVERY SYSTEM ASSEMBLIES AND ASSOCIATED METHODS FOR IMPLANTABLE MEDICAL DEVICES 有权
标题翻译：用于可植入医疗器械的输送系统组件和相关方法
公开(公告)号：US20130131591A1
公开(公告)日：2013-05-23
申请号：US13298973
申请日：2011-11-17
申请人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin
发明人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin
IPC分类号： A61M25/092 , A61M25/01 , A61M25/098
CPC分类号： A61N1/0587 , A61B2017/00331 , A61K9/0024 , A61M5/14276 , A61M25/0041 , A61M25/0102 , A61M25/0147 , A61M31/00 , A61N1/3622 , A61N1/37205 , A61N1/3756 , A61N2001/0578
摘要： A delivery system assembly includes an elongate outer tube, an elongate inner member extending within a lumen of the outer tube, and an articulation sheath surrounding the outer tube between a handle of the assembly and a distal-most portion of the outer tube. The outer tube is longitudinally moveable within the sheath; and an inner diameter of the sheath is preferably smaller than that of the handle and the distal-most portion of the outer tube. Navigation of the assembly through a venous system, for deployment of an implantable medical device, is facilitated by deflection of the sheath, to orient a distal-most portion of the outer tube, within which an entirety of the medical device is contained/loaded, and by subsequent advancement of the distal-most portion, with respect to the sheath, to move the distal end of the inner member, along with the contained/loaded device into proximity with a target implant site.
摘要翻译：输送系统组件包括细长的外管，在外管的内腔内延伸的细长内部构件，以及围绕组件的手柄和外管的最远部分之间的外管围绕的关节护套。外管可在鞘内纵向移动; 并且护套的内径优选地小于手柄和外管的最远部分的内径。通过静脉系统的导引，用于部署可植入医疗装置，通过护套的偏转来促进，以使外管的最远端部分定向，其中整个医疗装置被包含/装载在该外管的最远部分，并且通过相对于护套随后推进最远部分，将内部构件的远端与所容纳/加载的装置一起移动到目标植入部位附近。

15. 发明申请

US20120296222A1 Implantable Medical Sensor and Anchoring System 审中-公开
公开(公告)号：US20120296222A1
公开(公告)日：2012-11-22
申请号：US13109409
申请日：2011-05-17
申请人： Erik Griswold , James Calvin Allan , Rudy Beasley
发明人： Erik Griswold , James Calvin Allan , Rudy Beasley
IPC分类号： A61B5/0215
CPC分类号： A61B5/02152 , A61B5/6876 , A61B5/6882
摘要： A medical device adapted to be implanted in a vessel of a human body includes a housing that contains means for performing medical functions and an anchor for supporting the housing in an intended location and orientation within the vessel. The anchor is expandable from a low profile configuration adapted for delivery to an expanded configuration for engagement with the vessel wall. The anchor and delivery device are adapted to enable the medical device to be retrieved and repositioned or removed from the vessel. The anchor is adapted to apply sufficient force against the vessel wall to maintain the anchor in place but less force than that required to provide scaffolding support for the vessel.

16. 发明授权

US08226705B2 Methods for forming an orthogonal end on a helical stent 有权
标题翻译：在螺旋支架上形成正交端的方法
公开(公告)号：US08226705B2
公开(公告)日：2012-07-24
申请号：US12693571
申请日：2010-01-26
申请人： Erik Griswold
发明人： Erik Griswold
IPC分类号： A61F2/82
CPC分类号： B21F45/008 , A61F2/88 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91558 , B21F1/04 , B21F3/02 , B23K31/027 , B23K2101/22 , B23K2201/22 , Y10T29/49826
摘要： A method of manufacturing a stent includes forming a wave form having a plurality of struts and a plurality of crowns. Each crown connects two adjacent struts. The wave form has a center and two portions extending from opposite sides of the center. The method includes wrapping a first portion of the wave form about a longitudinal axis in a first direction at a first pitch angle, starting at the center of the wave form, to define at least one turn oriented at the first pitch angle, and wrapping a second portion of the wave form about the longitudinal axis in a second direction that is opposite the first direction at a second pitch angle, starting at the center of the wave form, to define at least one turn oriented at the second pitch angle. The first pitch angle is opposite the second pitch angle.
摘要翻译：制造支架的方法包括形成具有多个支柱和多个牙冠的波形。每个皇冠连接两个相邻的支柱。波形具有从中心的相对侧延伸的中心和两部分。该方法包括以波形中心开始的第一俯仰角沿着第一方向围绕纵向轴线的第一部分包围第一部分，以限定以第一俯仰角定向的至少一个转弯，并且包裹一个波形的第二部分在第二方向上以与第一方向相反的第二方向围绕纵向轴线以第二俯仰角从波形的中心开始，以限定以第二俯仰角定向的至少一个转弯。第一桨距角与第二俯仰角相反。

17. 发明申请

US20110071615A1 Methods for Forming an Orthogonal End on a Helical Stent 有权
标题翻译：在螺旋支架上形成正交末端的方法
公开(公告)号：US20110071615A1
公开(公告)日：2011-03-24
申请号：US12693571
申请日：2010-01-26
申请人： Erik Griswold
发明人： Erik Griswold
IPC分类号： A61F2/82 , B23P11/00
CPC分类号： B21F45/008 , A61F2/88 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91558 , B21F1/04 , B21F3/02 , B23K31/027 , B23K2101/22 , B23K2201/22 , Y10T29/49826
摘要： A method of manufacturing a stent includes forming a wave form having a plurality of struts and a plurality of crowns. Each crown connects two adjacent struts. The wave form has a center and two portions extending from opposite sides of the center. The method includes wrapping a first portion of the wave form about a longitudinal axis in a first direction at a first pitch angle, starting at the center of the wave form, to define at least one turn oriented at the first pitch angle, and wrapping a second portion of the wave form about the longitudinal axis in a second direction that is opposite the first direction at a second pitch angle, starting at the center of the wave form, to define at least one turn oriented at the second pitch angle. The first pitch angle is opposite the second pitch angle.
摘要翻译：制造支架的方法包括形成具有多个支柱和多个牙冠的波形。每个皇冠连接两个相邻的支柱。波形具有从中心的相对侧延伸的中心和两部分。该方法包括以波形中心开始的第一俯仰角沿着第一方向围绕纵向轴线的第一部分包围第一部分，以限定以第一俯仰角定向的至少一个转弯，并且包裹一个波形的第二部分在第二方向上以与第一方向相反的第二方向围绕纵向轴线以第二俯仰角从波形的中心开始，以限定以第二俯仰角定向的至少一个转弯。第一桨距角与第二俯仰角相反。

18. 发明授权

US09060889B2 Methods for forming an orthogonal end on a helical stent 有权
标题翻译：在螺旋支架上形成正交端的方法
公开(公告)号：US09060889B2
公开(公告)日：2015-06-23
申请号：US12693593
申请日：2010-01-26
申请人： Richard Bliss , Justin Goshgarian , Rui Lam , Padraig Savage , Erik Griswold , Gianfranco Pellegrini , Matthew Baldwin , Lance Ensign
发明人： Richard Bliss , Justin Goshgarian , Rui Lam , Padraig Savage , Erik Griswold , Gianfranco Pellegrini , Matthew Baldwin , Lance Ensign
IPC分类号： A61F2/06 , A61F2/88 , A61F2/915
CPC分类号： B21F45/008 , A61F2/88 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91558 , B21F1/04 , B21F3/02 , B23K31/027 , B23K2101/22 , B23K2201/22 , Y10T29/49826
摘要： A stent includes a continuous wave form having a plurality of struts and a plurality of crowns throughout the wave form. Each crown connects two adjacent struts. The wave form is wrapped around a longitudinal axis to define a central portion and two end portions located on opposite sides the central portion. The central portion includes a plurality of turns wrapped around the longitudinal axis and oriented at a first pitch angle relative to the longitudinal axis. The end portions each include a plurality of turns wrapped around the longitudinal axis and oriented at different pitch angles, and an end turn oriented at an angle relative to the longitudinal axis. The different pitch angles of the end portions are between the first pitch angle and the angle of the end turn relative to the longitudinal axis.
摘要翻译：支架包括具有整个波浪形状的多个支柱和多个冠部的连续波形。每个皇冠连接两个相邻的支柱。波形围绕纵向轴线包围以限定位于中心部分的相对侧上的中心部分和两个端部部分。中心部分包括围绕纵向轴线缠绕并相对于纵向轴线以第一俯仰角定向的多个匝。端部分别包括围绕纵向轴线缠绕并以不同的俯仰角定向的多个匝和相对于纵向轴线成一定角度定向的端匝。端部的不同桨距角位于第一桨距角和端匝相对于纵向轴线的角度之间。

19. 发明申请

US20130255347A1 METHOD AND APPARATUS FOR CREATING FORMED ELEMENTS USED TO MAKE WOUND STENTS 有权
标题翻译：用于创建用于制造伤口的成形元件的方法和装置
公开(公告)号：US20130255347A1
公开(公告)日：2013-10-03
申请号：US13438732
申请日：2012-04-03
申请人： Lance Ensign , Erik Griswold
发明人： Lance Ensign , Erik Griswold
IPC分类号： B21D13/00 , B21F1/04
CPC分类号： B21F45/008 , A61F2/86 , A61F2/88 , A61F2/90 , A61F2/915 , A61F2240/001 , B21F1/04
摘要： A method for forming a wave form for a stent includes moving a first forming portion of a first forming member across an axis along which a formable material is provided in a first direction substantially perpendicular to the axis to engage and deform the formable material while engaging the formable material with a first forming portion of the second forming member. The method includes moving the first forming portion of the first forming member and the first forming portion of the second forming member across the axis in a second direction that is substantially opposite the first direction to draw and form the formable material over the first forming portion of the second forming member, disengaging the first forming member from the formable material, and rotating the first forming member to position a second forming portion of the first forming member to face the formable material.
摘要翻译：用于形成用于支架的波形的方法包括使第一成形部件的第一成形部分沿着基本上垂直于轴线的第一方向穿过可成形材料的轴线移动，以使可成形材料接合和变形，同时接合可成形材料，其具有第二成形构件的第一形成部分。该方法包括使第一成形部件的第一成形部分和第二成形部件的第一成形部分沿着与第一方向基本相反的第二方向跨越轴线移动，以在第一成形部件的第一成形部分上方形成可成形材料所述第二成形构件将所述第一成形构件与所述可成形材料分离，并且使所述第一成形构件旋转以将所述第一成形构件的第二成形部分定位成可成形材料。

20. 发明申请

US20120239002A1 Catheter With Deflectable Cap 有权
标题翻译：导管带可挠性盖帽
公开(公告)号：US20120239002A1
公开(公告)日：2012-09-20
申请号：US13047525
申请日：2011-03-14
申请人： Erik Griswold
发明人： Erik Griswold
IPC分类号： A61M25/00
CPC分类号： A61M25/0074 , A61M2025/0079
摘要： A catheter system for delivery of a medical implant, the system including a cap removably covering an open distal end of a catheter. An elongate actuator wire is fixedly attached to the cap, extends through a lumen of the catheter, and has a distal region that can assume a pre-formed shape when unconstrained by the catheter lumen. The pre-formed shape of the wire distal region defines a bend adapted to laterally deflect the cap from the catheter distal end when assuming the pre-formed shape. At least a portion of the lumen adjacent the catheter distal end is sized and shaped to slidably receive the medical implant alongside the actuator wire. A push rod extends through the catheter lumen for ejecting the medical implant from the catheter distal end. Methods of using the invention are also disclosed.
摘要翻译：一种用于输送医疗植入物的导管系统，该系统包括可移除地覆盖导管的开放远端的盖。细长致动器线固定地附接到帽，延伸穿过导管的内腔，并且具有远端区域，当未被导管内腔受约束时，可以呈现预成形形状。电线远端区域的预先形成的形状限定了弯曲部，其适于在假设预成形形状时使帽从导管远端侧向偏转。与导管远端相邻的腔的至少一部分的尺寸和形状被设计成沿着致动器线可滑动地容纳医用植入物。推杆延伸穿过导管内腔，用于从导管远端喷射医用植入物。还公开了使用本发明的方法。

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