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1. 发明申请

US20150045868A1 IMPLANTABLE MEDICAL DEVICE FIXATION 审中-公开
标题翻译：可植入医疗器械固定
公开(公告)号：US20150045868A1
公开(公告)日：2015-02-12
申请号：US13959808
申请日：2013-08-06
申请人： Matthew D. Bonner , Thomas A. Anderson , William A. Berthiaume , Noelle C. Hurtig
发明人： Matthew D. Bonner , Thomas A. Anderson , William A. Berthiaume , Noelle C. Hurtig
IPC分类号： A61N1/375 , A61N1/362
CPC分类号： A61N1/3756 , A61N1/0573 , A61N1/362 , A61N1/37205 , A61N1/37518
摘要： Various fixation techniques for implantable medical device (IMDs) are described. In one example, an assembly comprises an IMD; and a set of active fixation tines attached to the IMD. The active fixation tines in the set are deployable from a spring-loaded position in which distal ends of the active fixation tines point away from the IMD to a hooked position in which the active fixation tines bend back towards the IMD. The active fixation tines are configured to secure the IMD to a patient tissue when deployed while the distal ends of the active fixation tines are positioned adjacent to the patient tissue.
摘要翻译：描述了用于可植入医疗装置（IMD）的各种固定技术。在一个示例中，组件包括IMD; 以及一组附加在IMD上的活动固定齿。组合中的主动固定齿可从弹簧加载位置展开，其中活动固定尖端的远端指向远离IMD的钩状位置，其中主动固定齿向IMD向后弯曲。活动的固定齿构造成当展开时将IMD固定到患者组织，同时主动固定齿的远端定位成与患者组织相邻。

2. 发明申请

US20130131591A1 DELIVERY SYSTEM ASSEMBLIES AND ASSOCIATED METHODS FOR IMPLANTABLE MEDICAL DEVICES 有权
标题翻译：用于可植入医疗器械的输送系统组件和相关方法
公开(公告)号：US20130131591A1
公开(公告)日：2013-05-23
申请号：US13298973
申请日：2011-11-17
申请人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin
发明人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin
IPC分类号： A61M25/092 , A61M25/01 , A61M25/098
CPC分类号： A61N1/0587 , A61B2017/00331 , A61K9/0024 , A61M5/14276 , A61M25/0041 , A61M25/0102 , A61M25/0147 , A61M31/00 , A61N1/3622 , A61N1/37205 , A61N1/3756 , A61N2001/0578
摘要： A delivery system assembly includes an elongate outer tube, an elongate inner member extending within a lumen of the outer tube, and an articulation sheath surrounding the outer tube between a handle of the assembly and a distal-most portion of the outer tube. The outer tube is longitudinally moveable within the sheath; and an inner diameter of the sheath is preferably smaller than that of the handle and the distal-most portion of the outer tube. Navigation of the assembly through a venous system, for deployment of an implantable medical device, is facilitated by deflection of the sheath, to orient a distal-most portion of the outer tube, within which an entirety of the medical device is contained/loaded, and by subsequent advancement of the distal-most portion, with respect to the sheath, to move the distal end of the inner member, along with the contained/loaded device into proximity with a target implant site.
摘要翻译：输送系统组件包括细长的外管，在外管的内腔内延伸的细长内部构件，以及围绕组件的手柄和外管的最远部分之间的外管围绕的关节护套。外管可在鞘内纵向移动; 并且护套的内径优选地小于手柄和外管的最远部分的内径。通过静脉系统的导引，用于部署可植入医疗装置，通过护套的偏转来促进，以使外管的最远端部分定向，其中整个医疗装置被包含/装载在该外管的最远部分，并且通过相对于护套随后推进最远部分，将内部构件的远端与所容纳/加载的装置一起移动到目标植入部位附近。

3. 发明授权

US5846259A Telescoping catheter and method of use 失效
标题翻译：伸缩导管及使用方法
公开(公告)号：US5846259A
公开(公告)日：1998-12-08
申请号：US845307
申请日：1996-12-31
申请人： William A. Berthiaume
发明人： William A. Berthiaume
IPC分类号： A61F2/958 , A61M25/00 , A61M25/01 , A61M29/00
CPC分类号： A61M25/00 , A61M25/10 , A61M2025/0175 , A61M25/0169
摘要： A catheter wherein the "effective over-the-wire" length is adjustable. The catheter includes an elongated inflation shaft having a longitudinal inflation lumen, an extension shaft disposed distal to the inflation shaft and through which the inflation lumen is continued, a balloon element disposed at the distal end of the extension shaft and in fluid communication with the inflation lumen, a guidewire shaft having a longitudinal guidewire lumen which extends from the distal end of the balloon member, through the balloon member and the extension shaft, to the proximal end of the extension shaft, and a telescoping portion. The telescoping portion comprising first and second telescoping tubes which are slidably mounted on the inflation shaft and the extension shaft. The first and second telescoping tubes are sized so that the first telescoping tube can be retracted into the second telescoping tube. The extension shaft is sized so that it can be retracted into the first telescoping tube. The effective "over-the-wire length" of the telescoping balloon catheter can be reduced by retracting the first telescoping tube and the extension tube into the second telescoping tube. In another embodiment, the telescoping portion comprises three telescoping tubes, which results in a greater reduction of the effective "over-the-wire length."
摘要翻译：导管，其中“有效的线上”长度是可调节的。导管包括细长的充气轴，其具有纵向充气腔，延伸轴设置在充气轴的远侧并且充气腔持续通过该延伸轴，球囊元件设置在延伸轴的远端处并与膨胀流体连通具有从球囊构件的远端延伸通过气囊构件和延伸轴的纵向导丝管的导丝轴到延伸轴的近端以及伸缩部分。伸缩部分包括可滑动地安装在膨胀轴和延伸轴上的第一和第二伸缩管。第一和第二伸缩管的尺寸使得第一伸缩管能够缩回到第二伸缩管中。延伸轴的尺寸使得其可以缩回到第一伸缩管中。可以通过将第一伸缩管和延伸管缩回到第二伸缩管中来缩小伸缩气囊导管的有效“超线长度”。在另一个实施例中，伸缩部分包括三个伸缩管，其导致有效的“在线长度”的更大的减小。

4. 发明授权

US5827241A Rapid exchange guidewire mechanism 失效
标题翻译：快速交换导丝机制
公开(公告)号：US5827241A
公开(公告)日：1998-10-27
申请号：US479680
申请日：1995-06-07
申请人： Nareak Douk , Richard A. Gambale , William A. Berthiaume
发明人： Nareak Douk , Richard A. Gambale , William A. Berthiaume
IPC分类号： A61M25/01 , A61M25/09 , A61M25/00
CPC分类号： A61M25/0169 , A61M25/0113 , A61M25/09 , A61M25/09041
摘要： A method and apparatus are provided for withdrawing an indwelling over-the-wire catheter from an indwelling guidewire in which the guidewire is of a conventional length and is maintained in its indwelling position as the catheter is withdrawn. The position of the guidewire is maintained by constraining a segment of the catheter shaft and its included guidewire in a non-linear configuration such that the guidewire remains in its position as the catheter is withdrawn. The invention may be used to perform catheter exchanges without requiring the use of exchange wires, extension wires, rapid exchange catheters or special devices to connect the guidewire to the guide catheter.
摘要翻译：提供了一种方法和装置，用于从留置导丝中取出留置的在线导管，其中导丝是常规长度的，并且当导管被取出时保持在其留置位置。通过将导管轴的一部分和其包括的导丝约束成非线性构造来维持导丝的位置，使得当导管被拔出时导丝保持在其位置。本发明可以用于执行导管交换，而不需要使用交换线，延长线，快速交换导管或特殊装置将导丝连接到引导导管。

5. 发明授权

US5161534A Tool for manipulating a medical guidewire 失效
标题翻译：用于操纵医疗导线的工具
公开(公告)号：US5161534A
公开(公告)日：1992-11-10
申请号：US755094
申请日：1991-09-05
申请人： William A. Berthiaume
发明人： William A. Berthiaume
IPC分类号： A61M25/01
CPC分类号： A61M25/09041 , A61M25/01 , A61M2025/09116 , A61M2025/107 , A61M25/09
摘要： A laterally attachable and detachable tool for manipulating a guidewire includes a cylindrical body that terminates in a collet. A nut is threaded to the collet and can be tightened to draw the collet arms inwardly. The body and the nut each include a lateral slot of a width to receive the guidewire. The slot in the nut is registrable with the slot in the body to form a continuous slot, receptive to the guidewire, along the length of the tool.
摘要翻译：用于操纵导丝的横向可附接和可拆卸的工具包括终止于夹头中的圆柱体。螺母被拧到夹头上，并可以拧紧以将夹头臂向内拉。主体和螺母各自包括宽度的横向狭槽以接收导丝。螺母中的槽可以与主体中的槽配准，以沿着工具的长度形成一个可接受导丝的连续槽。

6. 发明授权

US08945146B2 Delivery system assemblies and associated methods for implantable medical devices 有权
标题翻译：可植入医疗器械的输送系统组件和相关方法
公开(公告)号：US08945146B2
公开(公告)日：2015-02-03
申请号：US13279835
申请日：2011-10-24
申请人： H. Allan Steingisser , Don H. Tran , William A. Berthiaume , Brent L. Locsin
发明人： H. Allan Steingisser , Don H. Tran , William A. Berthiaume , Brent L. Locsin
IPC分类号： A61B19/00 , A61N1/372 , A61N1/375 , A61N1/362 , A61N1/05
CPC分类号： A61N1/37205 , A61N1/3622 , A61N1/3756 , A61N2001/0578
摘要： A delivery system assembly includes an outer tube, an inner member, extending within a lumen of the outer tube, and a deflectable shaft, extending within the outer tube lumen and around the inner member; the tube and inner member are longitudinally moveable with respect to the shaft, and a distal end of the inner member is located distal to the shaft within the tube lumen. A medical device can be loaded into the tube lumen, along a distal-most portion of the tube, and contained between the inner member and a distal opening of the tube lumen. Deflecting the shaft orients the distal-most portion for navigation of the assembly, and, when the distal end of the inner member is engaged within the tube lumen, distal movement of the tube, with respect to the shaft, causes similar distal movement of the inner member and the loaded medical device toward an implant site.
摘要翻译：输送系统组件包括在外管的内腔中延伸的外管，内部构件和在外管腔内并围绕内部构件延伸的可偏转的轴; 管和内部构件可以相对于轴纵向移动，并且内部构件的远端位于管腔内远离轴的远侧。医疗装置可以沿着管的最远部分装载到管腔中，并且容纳在内部构件和管腔的远端开口之间。轴的偏转定位用于组件导航的最远部分，并且当内部构件的远端接合在管腔内时，管的相对于轴的远端运动导致相似的远端移动内部构件和装载的医疗装置朝向植入物位置。

7. 发明授权

US08945145B2 Delivery system assemblies for implantable medical devices 有权
标题翻译：可植入医疗器械的输送系统组件
公开(公告)号：US08945145B2
公开(公告)日：2015-02-03
申请号：US13239990
申请日：2011-09-22
申请人： Don H. Tran , William A. Berthiaume , H. Allan Steingisser , Maria Valdovinos , Brent L. Locsin , Suruchi Anand
发明人： Don H. Tran , William A. Berthiaume , H. Allan Steingisser , Maria Valdovinos , Brent L. Locsin , Suruchi Anand
IPC分类号： A61B19/00 , A61B17/34 , A61N1/372 , A61N1/375 , A61N1/362
CPC分类号： A61B17/3468 , A61N1/362 , A61N1/37205 , A61N1/3756
摘要： A delivery system assembly includes an elongate inner member that extends distally through a lumen of an elongate outer tube of the assembly; the outer tube is moveable relative to the inner member between first and second positions to deploy an implantable medical device that is held within the outer tube lumen. The inner member may include a flared distal end that abuts, and preferably conforms to, the proximal end of the device, when the device is held within the outer tube lumen. The assembly further includes a stability sheath that surrounds a limited length of the outer tube, in proximity to the handle, to provide an interface for both an operator, who handles the assembly, and for an introducer sheath that provides passage for the assembly into the venous system, so that movement of the outer tube is not hindered by either during device deployment.
摘要翻译：递送系统组件包括细长的内部构件，其向远侧延伸穿过组件的细长外管的内腔; 外管可在第一和第二位置之间相对于内部构件移动以展开保持在外管内腔内的可植入医疗装置。当装置保持在外管腔内时，内部构件可以包括邻近并且优选地符合装置的近端的扩口远端。组件还包括稳定的护套，其围绕外管的有限长度围绕手柄，以提供用于处理组件的操作者和导引器护套的接口，所述引导器护套为组件提供通道静脉系统，使得在设备部署期间外部管的运动不会受到阻碍。

8. 发明申请

US20130131693A1 DELIVERY SYSTEM ASSEMBLIES FOR IMPLANTABLE MEDICAL DEVICES 有权
标题翻译：用于可植入医疗器械的输送系统组件
公开(公告)号：US20130131693A1
公开(公告)日：2013-05-23
申请号：US13298821
申请日：2011-11-17
申请人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin , James C. Allan
发明人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin , James C. Allan
IPC分类号： A61B19/00
CPC分类号： A61N1/37205 , A61B5/0422 , A61B5/6869 , A61B5/6882 , A61B2560/066 , A61M25/0136 , A61M25/0147 , A61N1/3756
摘要： An inner subassembly of a delivery system assembly extends within a lumen of an elongate outer tube of the assembly, and includes a flared distal end, which is preferably configured to conform to a proximal end of an implantable medical device; a distal-most portion of the outer tube is sized to contain both the flared distal end and an entirety of the medical device. The inner subassembly includes a core, an elongate pull-wire, extending along the core, and a sheath surrounding the pull-wire and the core; the sheath includes a slot opening that allows the pull-wire to pass laterally therethrough. The assembly preferably has a pre-formed curvature along a length of the sheath, and the slot opening extends along the pre-formed curvature. The outer tube is longitudinally moveable relative to the inner subassembly, for example, to deploy the medical device.
摘要翻译：输送系统组件的内部子组件在组件的细长外管的内腔中延伸，并且包括扩口远端，其优选地构造成符合可植入医疗装置的近端; 外管的最远部分的尺寸被设计成容纳扩张的远端和整个医疗装置。所述内部子组件包括芯，沿所述芯延伸的细长拉线和围绕所述拉线和所述芯的护套; 护套包括允许拉线横向通过的槽口。组件优选地沿着护套的长度具有预先形成的曲率，并且槽开口沿着预先形成的曲率延伸。外管可相对于内部子组件纵向移动，例如，以部署医疗装置。

9. 发明授权

US06110146A Protector for catheter balloon with guidewire backloading system 失效
标题翻译：导丝气囊保护器，带导丝后退系统
公开(公告)号：US06110146A
公开(公告)日：2000-08-29
申请号：US164166
申请日：1998-09-30
申请人： William A. Berthiaume , Nareak Douk
发明人： William A. Berthiaume , Nareak Douk
IPC分类号： A61M25/01 , A61M25/06 , A61M29/02 , A61M5/178
CPC分类号： A61M25/09041 , A61M2025/0188 , A61M2025/1081 , A61M2029/025 , A61M25/0668
摘要： A balloon protector for the balloon of a dilatation catheter includes a distally extending flared section that defines a funnel receptive to a guidewire in order to facilitate backloading of the guidewire into the catheter.
摘要翻译：用于扩张导管气囊的气球保护器包括远端延伸的扩口部分，其限定了容纳导丝的漏斗，以便于将导丝导入导管中。

10. 发明授权

US6099496A Catheter having a variable length shaft segment and method of use 失效
标题翻译：导管具有可变长度的轴段和使用方法
公开(公告)号：US6099496A
公开(公告)日：2000-08-08
申请号：US164008
申请日：1998-09-30
申请人： William A. Berthiaume , Gregory Toso
发明人： William A. Berthiaume , Gregory Toso
IPC分类号： A61M29/02 , A61M29/00
CPC分类号： A61M25/104
摘要： The invention relates to a catheter device and a method of use to enable catheter exchange over a conventional length guidewire without the use of a guidewire extension or exchange wire. The catheter device includes an elongated inflation shaft having a longitudinal inflation lumen, an extension shaft having a longitudinal extension lumen coupled in fluid communication with the inflation lumen, a balloon member disposed at the distal end of the extension shaft and in fluid communication with the inflation lumen, a guidewire shaft having a longitudinal guidewire lumen which extends from the distal end of the balloon member, through the balloon member and extension shaft, to the proximal end of the extension shaft, and a variable length shaft coupled to the proximal end of the extension shaft. The variable length shaft comprises an elastomeric material which may be stretched from a relaxed state of about 10 centimeters to a fully extended state of about 140 centimeters.
摘要翻译：本发明涉及一种导管装置和一种用于在常规长度导丝上进行导管切换的方法，而不需要使用导丝延伸或交换线。导管装置包括具有纵向充气腔的细长充气轴，延伸轴，其具有与膨胀腔流体连通的连接的纵向延伸腔;设置在延伸轴的远端并与膨胀流体连通的球囊构件导丝轴，其具有从球囊构件的远端延伸穿过球囊构件和延伸轴的纵向导丝内腔到延伸轴的近端，以及可变长度的轴，其耦合到延长轴。可变长度轴包括弹性体材料，其可以从约10厘米的松弛状态拉伸至约140厘米的完全伸展状态。

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