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11. 发明申请

US20140288076A1 HETEROARYL COMPOUNDS AND THEIR USES 审中-公开
标题翻译： HETEROARYL化合物及其用途
公开(公告)号：US20140288076A1
公开(公告)日：2014-09-25
申请号：US14295398
申请日：2014-06-04
申请人： Paul A. Barsanti , Cheng Hu , Jeff Jin , Robert Keyes , Robert Kucejko , Xiaodong Lin , Yue Pan , Keith B. Pfister , Martin Sendzik , James Sutton , Lifeng Wan
发明人： Paul A. Barsanti , Cheng Hu , Jeff Jin , Robert Keyes , Robert Kucejko , Xiaodong Lin , Yue Pan , Keith B. Pfister , Martin Sendzik , James Sutton , Lifeng Wan
IPC分类号： C07D409/14 , C07D401/14 , C07D405/14 , C07D401/04
CPC分类号： A61K31/497 , C07D213/74 , C07D241/20 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要： The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided is a method of treating a disease or condition mediated by CDK9.
摘要翻译：本发明提供式（I）化合物及其药学上可接受的盐，对映体，立体异构体，旋转异构体，互变异构体，非对映体或其外消旋物。还提供了治疗由CDK9介导的疾病或病症的方法。

12. 发明申请

US20140056880A1 TRIAZOLE COMPOUNDS AS KSP INHIBITORS 审中-公开
标题翻译：三唑化合物作为KSP抑制剂
公开(公告)号：US20140056880A1
公开(公告)日：2014-02-27
申请号：US14012167
申请日：2013-08-28
申请人： Tinya Abrams , Paul Barsanti , Yu Ding , David Duhl , Wooseok Han , Cheng Hu , Yue Pan
发明人： Tinya Abrams , Paul Barsanti , Yu Ding , David Duhl , Wooseok Han , Cheng Hu , Yue Pan
IPC分类号： C07D403/12 , C07D413/14 , C07D207/10 , A61K31/5377 , A61K45/06 , C07D405/14 , A61K31/4196
CPC分类号： C07D403/12 , A61K31/4196 , A61K31/5377 , A61K45/06 , C07D207/10 , C07D249/08 , C07D405/12 , C07D405/14 , C07D413/14
摘要： The present invention provides triazole compounds of Formula I: as further described herein. The invention also provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of Formula I, and a method of treating a disorder mediated, at least in part, by KSP in a mammalian patient comprising administering to a mammalian patient in need of such treatment a therapeutically effective amount of a compound of Formula I.
摘要翻译：本发明提供式I的三唑化合物：如本文进一步描述的。本发明还提供了包含治疗有效量的式I化合物的药物组合物，以及治疗在哺乳动物患者中至少部分地由KSP介导的病症的方法，包括向需要这种治疗的哺乳动物患者施用治疗有效量的式I化合物。

13. 发明授权

US08195690B2 Method and system for constructing XML query to schema variable XML documents 失效
标题翻译：用于构建XML查询到模式变量XML文档的方法和系统
公开(公告)号：US08195690B2
公开(公告)日：2012-06-05
申请号：US12431191
申请日：2009-04-28
申请人： Xue Qiao Hou , Hui-I Hsiao , Gang Hu , Bo Li , Yue Pan
发明人： Xue Qiao Hou , Hui-I Hsiao , Gang Hu , Bo Li , Yue Pan
IPC分类号： G06F7/00
CPC分类号： G06F17/30929 , G06F17/30932
摘要： An XML querying method and system for constructing an XQuery/XPath query to a schema variable XML document. The method includes: receiving the query from a client computer; generating a tree structure; and generating, by query rewriting, an XQuery/XPath for the XML document based on the tree structure and configurable query constraints. The system includes: a tree structure generating unit for generating a tree structure; and a query writing unit for generating an XQuery/XPath query for the XML document based on the tree structure and configurable query constraints.
摘要翻译：用于将XQuery / XPath查询构造到模式变量XML文档的XML查询方法和系统。该方法包括：从客户端计算机接收查询; 生成树结构; 并通过查询重写生成基于树结构和可配置查询约束的XML文档的XQuery / XPath。该系统包括：用于生成树结构的树结构生成单元; 以及查询写入单元，用于基于树结构和可配置的查询约束生成用于XML文档的XQuery / XPath查询。

14. 发明申请

US20110106843A1 METHOD AND SYSTEM FOR DETERMINING NODE TO BE MATERIALIZED 有权
标题翻译：用于确定要素材的节点的方法和系统
公开(公告)号：US20110106843A1
公开(公告)日：2011-05-05
申请号：US12913570
申请日：2010-10-27
申请人： Yue Pan , Xing Zhi Sun , Lin Hao Xu
发明人： Yue Pan , Xing Zhi Sun , Lin Hao Xu
IPC分类号： G06F17/30
CPC分类号： G06F17/30457
摘要： A dependency graph of rule predicates without strongly connected sub-graph is obtained. The dependency graph indicates the dependency among the rule predicates. An update frequency of node in the dependency graph is calculated, and a query frequency of node in the dependency graph is also calculated. Furthermore, a runtime query cost value and a materialization cost value of the node are calculated based on the query frequency and update frequency. Node to be materialized are determined based on the runtime query cost value and the materialization cost value. A rule predicate corresponding to the node to be materialized is the rule predicate to be materialized. In at least some instances, an exemplary technical effect is that the return time of result of runtime query is saved and the affect by the data update is reduced when a query is performed in relation data reasoning system constructed with rule predicates.
摘要翻译：获得没有强连接子图的规则谓词的依赖图。依赖图表示规则谓词之间的依赖关系。计算依赖图中节点的更新频率，并计算依赖图中节点的查询频率。此外，基于查询频率和更新频率来计算节点的运行时查询成本值和实现成本值。基于运行时查询成本值和实现成本值确定要实现的节点。与要实现的节点相对应的规则谓词是要实现的规则谓词。在至少一些情况下，示例性的技术效果是，当在关系数据推理系统构造的规则谓词中执行查询时，保存运行时查询的结果的返回时间，并且减少数据更新的影响。

15. 发明授权

US07424484B2 Path-based ranking of unvisited web pages 有权
标题翻译：基于路径的未访问网页排名
公开(公告)号：US07424484B2
公开(公告)日：2008-09-09
申请号：US10358941
申请日：2003-02-05
申请人： Xiaochuan Ma , Yue Pan , Hui Su
发明人： Xiaochuan Ma , Yue Pan , Hui Su
IPC分类号： G06F17/30
CPC分类号： G06F17/30864 , Y10S707/99933 , Y10S707/99936 , Y10S707/99943
摘要： Path-based ranking of unvisited Web pages for WWW crawling is provided, via identifying all the paths beginning with a “seed” URL and leading to visited relevant web pages as “good-path set”, and for each unvisited web page, identifying the paths beginning from the “seed” URL leading to it as “partial-path set”; classifying all the visited web pages and labeling each web Page with the labels of a class or classes it belongs to; training a statistic model for generalizing the common patterns among all ones of “good-path set”; and evaluating the “partial-path set” with the statistic model and ranking the unvisited web pages with the evaluation results.
摘要翻译：通过识别从“种子”URL开始的所有路径，并将访问过的相关网页导向为“良好路径集”，并为每个未访问的网页标识，以提供用于WWW抓取的未访问网页的基于路径的排名从“种子”URL开始的路径导致它作为“部分路径集”; 对所有访问的网页进行分类，并使用所属类别的标签将每个网页标注; 培养统一模式，推广“好路径”的共同模式; 并用统计模型评估“部分路径集”，并通过评估结果对未访问的网页进行排序。

16. 发明申请

US20080027932A1 APPARATUS OF GENERATING BROWSING PATHS FOR DATA AND METHOD FOR BROWSING DATA 失效
标题翻译：产生浏览数据的方法和浏览数据的方法的设备
公开(公告)号：US20080027932A1
公开(公告)日：2008-01-31
申请号：US11751181
申请日：2007-05-21
申请人： Jean-Sebastien Brunner , Li Ma , Yue Pan , Lei Zhang
发明人： Jean-Sebastien Brunner , Li Ma , Yue Pan , Lei Zhang
IPC分类号： G06F17/30
CPC分类号： G06F17/30873 , Y10S707/99932
摘要： The present invention provides a method and apparatus of generating browsing paths for data, a method for browsing data and a computer program product. According to one aspect of the invention, there is provided a method of generating browsing paths for data. Firstly, a plurality of candidate browsing paths based on a data model describing the data structure is generated; next for each of the plurality of candidate browsing paths, importance of the browsing path based on a portion of data corresponding to the browsing path in the data is calculated; and at least one of the plurality of candidate browsing paths based on the importance is selected.
摘要翻译：本发明提供了一种生成数据浏览路径的方法和装置，一种用于浏览数据的方法和一种计算机程序产品。根据本发明的一个方面，提供了一种生成用于数据的浏览路径的方法。首先，生成基于描述数据结构的数据模型的多个候选浏览路径; 接下来对于多个候选浏览路径中的每一个，计算基于与数据中的浏览路径相对应的数据的一部分的浏览路径的重要性; 并且基于重要性选择多个候选浏览路径中的至少一个。

17. 发明授权

US06794413B1 Compounds and related methods for inhibition of &ggr;-aminobutyric acid aminotransferase 有权
标题翻译：用于抑制γ-氨基丁酸氨基转移酶的化合物和相关方法
公开(公告)号：US06794413B1
公开(公告)日：2004-09-21
申请号：US10623152
申请日：2003-07-18
申请人： Richard B. Silverman , Yue Pan
发明人： Richard B. Silverman , Yue Pan
IPC分类号： A61K31557
CPC分类号： C07C229/48 , A61K31/557 , A61K2300/00
摘要： (1S, 3S)-3-Amino-4-difluoromethylene-1-cyclopentanoic acid illustrates a novel class of compounds as potent irreversible inhibitors of &ggr;-aminobutyric acid aminotransferase (GABA-AT). The corresponding monofluoro-substituted compounds also are potent time-dependent inhibitors of GABA-AT.
摘要翻译：（1S，3S）-3-氨基-4-二氟亚甲基-1-环戊酸说明了一类新颖的化合物作为γ-氨基丁酸转氨酶（GABA-AT）的有效不可逆抑制剂。相应的单氟取代的化合物也是GABA-AT的有效的时间依赖性抑制剂。

18. 发明授权

US09142768B2 Resistive memory with small electrode and method for fabricating the same 有权
标题翻译：具有小电极的电阻记忆及其制造方法
公开(公告)号：US09142768B2
公开(公告)日：2015-09-22
申请号：US13698799
申请日：2012-05-02
申请人： Yimao Cai , Jun Mao , Ru Huang , Shenghu Tan , Yinglong Huang , Yue Pan
发明人： Yimao Cai , Jun Mao , Ru Huang , Shenghu Tan , Yinglong Huang , Yue Pan
IPC分类号： H01L45/00
CPC分类号： H01L45/1253 , H01L45/04 , H01L45/122 , H01L45/1233 , H01L45/1273 , H01L45/146 , H01L45/1608 , H01L45/1616 , H01L45/1625
摘要： Systems and methods are disclosed involving a resistive memory with a small electrode, relating to the field of semiconductor resistive memory in ULSI. An illustrative resistive memory may include an Al electrode layer, a SiO2 layer, a Si layer, a resistive material layer and a lower electrode layer in sequence, wherein the Al electrode layer and the resistive material layer are electrically connected through one or more conductive channel and the conductive channel is formed by penetrating Al material into the Si layer via defects in the SiO2 layer and dissolving Si material into the Al material. Methods may include forming a lower electrode layer, a resistive layer, a Si layer and a SiO2 layer over a substrate; fabricating a Al electrode layer over the SiO2 layer; and performing an anneal process to the resultant structure. Consistent with innovations herein, a small electrode may be obtained via a conventional process.
摘要翻译：公开了涉及具有与ULSI中的半导体电阻性存储器的领域相关的具有小电极的电阻性存储器的系统和方法。示例性电阻存储器可以依次包括Al电极层，SiO 2层，Si层，电阻材料层和下电极层，其中Al电极层和电阻材料层通过一个或多个导电沟道电连接并且通过SiO 2层中的缺陷将Al材料穿过Si层而将Si材料溶解到Al材料中而形成导电通道。方法可以包括在衬底上形成下电极层，电阻层，Si层和SiO 2层; 在SiO 2层上制造Al电极层; 对所得到的结构进行退火处理。与本文的创新一致，可以通过常规方法获得小电极。

19. 发明授权

US08942036B2 Method for achieving four-bit storage using flash memory having splitting trench gate 有权
标题翻译：用于使用具有分裂沟槽栅极的闪存实现四位存储的方法
公开(公告)号：US08942036B2
公开(公告)日：2015-01-27
申请号：US13499596
申请日：2011-10-14
申请人： Yimao Cai , Ru Huang , Shiqiang Qin , Poren Tang , Yu Tang , Shenghu Tan , Xin Huang , Yue Pan
发明人： Yimao Cai , Ru Huang , Shiqiang Qin , Poren Tang , Yu Tang , Shenghu Tan , Xin Huang , Yue Pan
IPC分类号： G11C11/40 , H01L29/423 , G11C16/04 , H01L29/788 , H01L29/792
CPC分类号： H01L29/42352 , G11C16/0475 , H01L29/7887 , H01L29/7923
摘要： The present invention discloses a method for achieving four-bit storage by using a flash memory having a splitting trench gate. The flash memory with the splitting trench gate is disclosed in a Chinese patent No. 200710105964.2. At one side that each of two trenches is contacted with a channel, a programming for electrons is achieved by using a channel hot electron injection method; and at the other side that each of the two trenches is contacted with a source or a drain, a programming for electrons is achieved by using an FN injection method, so that a function of a four-bit storage of the device is achieved by changing a programming mode. Thus, a performance of the device is improved while a storage density is greatly increased.
摘要翻译：本发明公开了一种通过使用具有分割沟槽栅的闪存来实现四位存储的方法。具有分割沟槽栅的闪速存储器在中国专利No.200710105964.2中公开。在两个沟槽中的每一个与沟道接触的一侧，通过使用沟道热电子注入方法实现电子编程; 并且在另一侧，两个沟槽中的每一个与源极或漏极接触，通过使用FN注入方法来实现电子编程，使得通过改变器件的四位存储器的功能来实现一种编程模式。因此，提高了存储密度的装置的性能。

20. 发明申请

US20130324530A1 3-(AMINOARYL)-PYRIDINE COMPOUNDS 审中-公开
标题翻译： 3-（氨基） - 吡啶化合物
公开(公告)号：US20130324530A1
公开(公告)日：2013-12-05
申请号：US13885640
申请日：2011-11-17
申请人： William R. Antonios-McCrea , Paul A. Barsanti , Cheng Hu , Xianming Jin , Eric J. Martin , Yue Pan , Keith B. Pfister , Martin Sendzik , James Sutton , Lifeng Wan
发明人： William R. Antonios-McCrea , Paul A. Barsanti , Cheng Hu , Xianming Jin , Eric J. Martin , Yue Pan , Keith B. Pfister , Martin Sendzik , James Sutton , Lifeng Wan
IPC分类号： C07D213/74 , C07D401/14 , C07D409/14 , C07D405/14
CPC分类号： C07D213/74 , C07D401/14 , C07D405/14 , C07D409/14
摘要： The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided are pharmaceutical compositions containing these compounds and methods of treating a disease or condition mediated by CDK9 using these compounds and compositions.
摘要翻译：本发明提供式（I）化合物及其药学上可接受的盐，对映体，立体异构体，旋转异构体，互变异构体，非对映体或其外消旋物。还提供含有这些化合物的药物组合物和使用这些化合物和组合物治疗由CDK9介导的疾病或病症的方法。

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