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11. 发明授权

US08241939B2 Semiconductor nanowire sensor device and method for manufacturing the same 有权
标题翻译：半导体纳米线传感器装置及其制造方法
公开(公告)号：US08241939B2
公开(公告)日：2012-08-14
申请号：US12682571
申请日：2008-07-24
申请人： Chan Woo Park , Chang Geun Ahn , Jong Heon Yang , In Bok Baek , Chil Seong Ah , Han Young Yu , An Soon Kim , Tae Youb Kim , Moon Gyu Jang , Myung Sim Jun
发明人： Chan Woo Park , Chang Geun Ahn , Jong Heon Yang , In Bok Baek , Chil Seong Ah , Han Young Yu , An Soon Kim , Tae Youb Kim , Moon Gyu Jang , Myung Sim Jun
IPC分类号： H01L21/00 , H01L29/06
CPC分类号： H01L29/0665 , B82Y10/00 , B82Y15/00 , H01L29/0673 , H01L29/78696
摘要： A method for manufacturing a biosensor includes forming a silicon nanowire channel, etching a first conductivity-type single crystalline silicon layer which is a top layer of a Silicon-On-Insulator (SOI) substrate to form a first conductivity-type single crystalline silicon line pattern, doping both sidewalls of the first conductivity-type single crystalline silicon line pattern with impurities of a second conductivity-type opposite to the first conductivity-type to form a second conductivity-type channel, forming second conductivity-type pads for forming electrodes at both ends of the first conductivity-type single crystalline silicon line pattern, forming, in an undoped region of the first conductivity-type single crystalline silicon line pattern, a first electrode for applying a reverse-bias voltage to insulate the first conductivity-type single crystalline silicon line pattern and the second conductivity-type channel from each other, and forming second electrodes for applying a bias voltage across the second conductivity-type channel on the second conductivity-type pad.
摘要翻译：制造生物传感器的方法包括形成硅纳米线通道，蚀刻作为绝缘体上硅（SOI）衬底的顶层的第一导电型单晶硅层，以形成第一导电型单晶硅线以与第一导电类型相反的第二导电类型的杂质掺杂第一导电型单晶硅线图案的两个侧壁以形成第二导电型沟道，形成第二导电型垫，用于在第一导电型单晶硅线图案的两端，在第一导电型单晶硅线图案的未掺杂区域中形成用于施加反向偏置电压以使第一导电型单晶硅线型图案绝缘的第一电极晶体硅线图案和第二导电型沟道，并且形成用于施加双面的第二电极在第二导电型垫上的第二导电类型沟道上的电压。

12. 发明申请

US20110194976A1 DETECTION DEVICE AND SYSTEM 有权
标题翻译：检测装置和系统
公开(公告)号：US20110194976A1
公开(公告)日：2011-08-11
申请号：US12682545
申请日：2008-06-13
申请人： Chang Geun Ahn , Chan Woo Park , Jong Heon Yang , In Bok Baek , Chil Seong Ah , Han Young Yu , An Soon Kim , Tae Youb Kim , Moon Gyu Jang , Seon Hee Park
发明人： Chang Geun Ahn , Chan Woo Park , Jong Heon Yang , In Bok Baek , Chil Seong Ah , Han Young Yu , An Soon Kim , Tae Youb Kim , Moon Gyu Jang , Seon Hee Park
IPC分类号： G01N33/48 , H01L27/06
CPC分类号： G01N27/4145 , Y10T436/11
摘要： A detection device and system are provided. The detection device includes a detection capacitor and a Field Effect Transistor (FET). The detection capacitor has a reactive material layer reacting to a specific functional group in a fluid, and first and second electrodes disposed on the both surfaces of an insulating layer, and the FET has a source electrode connected with the second electrode, a gate electrode connected with the first electrode, and a drain electrode. Here, the insulating layer of the detection capacitor is thicker than a gate insulating layer of the FET.
摘要翻译：提供检测装置和系统。检测装置包括检测电容器和场效应晶体管（FET）。检测电容器具有与流体中的特定官能团反应的反应性物质层，以及设置在绝缘层两面的第一和第二电极，并且所述FET具有与所述第二电极连接的源电极，连接有栅电极与第一电极和漏电极。这里，检测电容器的绝缘层比FET的栅极绝缘层厚。

13. 发明申请

US20100270530A1 SEMICONDUCTOR NANOWIRE SENSOR DEVICE AND METHOD FOR MANUFACTURING THE SAME 有权
标题翻译：半导体纳米传感器器件及其制造方法
公开(公告)号：US20100270530A1
公开(公告)日：2010-10-28
申请号：US12682571
申请日：2008-07-24
申请人： Chan Woo Park , Chang Geun Ahn , Jong Heon Yang , In Book Baek , Chil Seong Ah , Han Young Yu , An Soon Kim , Tae Youb Kim , Moon Gyu Jang , Myung Sim Jun
发明人： Chan Woo Park , Chang Geun Ahn , Jong Heon Yang , In Book Baek , Chil Seong Ah , Han Young Yu , An Soon Kim , Tae Youb Kim , Moon Gyu Jang , Myung Sim Jun
IPC分类号： H01L29/775 , H01L21/336
CPC分类号： H01L29/0665 , B82Y10/00 , B82Y15/00 , H01L29/0673 , H01L29/78696
摘要： A method for manufacturing a biosensor device is provided. The method involves forming a silicon nanowire channel with a line width of several nanometers to several tens of nanometers using a typical photolithography process, and using the channel to manufacture a semiconductor nanowire sensor device. The method includes etching a first conductivity-type single crystalline silicon layer which is a top layer of a Silicon-On-Insulator (SOI) substrate to form a first conductivity-type single crystalline silicon line pattern, doping both sidewalls of the first conductivity-type single crystalline silicon line pattern with impurities of a second conductivity-type opposite to the first conductivity-type to form a second conductivity-type channel, forming second conductivity-type pads for forming electrodes at both ends of the first conductivity-type single crystalline silicon line pattern, forming, in an undoped region of the first conductivity-type single crystalline silicon line pattern, a first electrode for applying a reverse-bias voltage to insulate the first conductivity-type single crystalline silicon line pattern and the second conductivity-type channel from each other, and forming second electrodes for applying a bias voltage across the second conductivity-type channel on the second conductivity-type pad.
摘要翻译：提供一种制造生物传感器装置的方法。该方法包括使用典型的光刻工艺形成线宽为几纳米至几十纳米的硅纳米线通道，并使用该通道制造半导体纳米线传感器装置。该方法包括蚀刻作为绝缘体上硅（SOI）衬底的顶层的第一导电型单晶硅层，以形成第一导电型单晶硅线图案，掺杂第一导电型单晶硅线阵列的两个侧壁，形成具有与第一导电类型相反的第二导电类型的杂质的单晶硅线图案，以形成第二导电型沟道，形成用于在第一导电型单晶的两端形成电极的第二导电型焊盘硅线图案，在第一导电型单晶硅线图案的未掺杂区域中形成第一电极，用于施加反向偏置电压以使第一导电型单晶硅线图案和第二导电型并且形成用于在第二导通型通道上施加偏置电压的第二电极导电型垫。

14. 发明申请

US20120143513A1 BIO-SENSOR CHIP AND READER THEREOF 审中-公开
标题翻译：生物传感器芯片和读取器
公开(公告)号：US20120143513A1
公开(公告)日：2012-06-07
申请号：US13219197
申请日：2011-08-26
申请人： Jong-Heon YANG , Chang-Geun Ahn , Chan Woo Park , Chil Seong Ah , Wan Joong Kim , Kwang Hyo Chung , Yo Han Choi , Gun Yong Sung
发明人： Jong-Heon YANG , Chang-Geun Ahn , Chan Woo Park , Chil Seong Ah , Wan Joong Kim , Kwang Hyo Chung , Yo Han Choi , Gun Yong Sung
IPC分类号： G06F19/10
CPC分类号： G01N21/6454 , G01N21/01 , G01N2021/0106
摘要： Provided are a bio sensor chip and a reader thereof. The bio-sensor chip is optically addressed. The bio-sensor chip includes a word line control circuit and a bit line control circuit controlled by light provided from the bio-sensor chip reader. The bio-sensor chip does not require a peripheral circuit for driving word lines and bit lines, simplifying a fabrication process and reducing the area of the chip.
摘要翻译：提供了一种生物传感器芯片及其读取器。生物传感器芯片被光学寻址。生物传感器芯片包括由生物传感器芯片读取器提供的光控制的字线控制电路和位线控制电路。生物传感器芯片不需要用于驱动字线和位线的外围电路，简化制造工艺并减少芯片的面积。

15. 发明申请

US20110139637A1 METHOD AND APPARATUS FOR MEASURING ISOELECTRIC POINT USING FIELD EFFECT TRANSISTOR 失效
标题翻译：使用场效应晶体管测量电压点的方法和装置
公开(公告)号：US20110139637A1
公开(公告)日：2011-06-16
申请号：US13058120
申请日：2008-12-16
申请人： Chil Seong Ah , Ansoon Kim , Chan Woo Park , Chang-Geun Ahn , Jong-Heon Yang , In Bok Baek , Taeyoub Kim , Gun Yong Sung , Seon-Hee Park , Han Young Yu
发明人： Chil Seong Ah , Ansoon Kim , Chan Woo Park , Chang-Geun Ahn , Jong-Heon Yang , In Bok Baek , Taeyoub Kim , Gun Yong Sung , Seon-Hee Park , Han Young Yu
IPC分类号： G01N27/403 , G01N27/414
CPC分类号： G01N27/4145
摘要： Provided are a method and apparatus for measuring an isoelectric point using a field effect transistor. The method includes providing a field effect transistor including a substrate, source and drain electrodes disposed on the substrate and spaced apart from each other, and a channel region between the source and drain electrodes, providing a first electrolyte solution having a first concentration to the channel region of the field effect transistor and measuring a first current value of the channel region between the source and drain electrodes, providing a second electrolyte solution having a second concentration greater than the first concentration and measuring a second current value of the channel region between the source and drain electrodes, and determining as the isoelectric point of the field effect transistor or a material disposed on the field effect transistor using a difference between the first and second current values.
摘要翻译：提供了使用场效应晶体管测量等电点的方法和装置。该方法包括提供场效应晶体管，该场效应晶体管包括衬底，设置在衬底上的源电极和漏极彼此间隔开的沟道区，以及在源电极和漏电极之间的沟道区域，提供具有第一浓度到沟道的第一电解质溶液区域，并且测量源极和漏极之间的沟道区的第一电流值，提供具有大于第一浓度的第二浓度的第二电解质溶液，并测量源极之间的沟道区的第二电流值和漏电极，并且使用第一和第二电流值之间的差来确定场效应晶体管的等电点或设置在场效应晶体管上的材料。

16. 发明授权

US08169006B2 Bio-sensor chip for detecting target material 有权
标题翻译：用于检测目标材料的生物传感器芯片
公开(公告)号：US08169006B2
公开(公告)日：2012-05-01
申请号：US12561032
申请日：2009-09-16
申请人： Taeyoub Kim , Jong-Heon Yang , Chang-Geun Ahn , Chan Woo Park , Chil Seong Ah , Ansoon Kim , In Bok Baek , Gun Yong Sung , Seon Hee Park
发明人： Taeyoub Kim , Jong-Heon Yang , Chang-Geun Ahn , Chan Woo Park , Chil Seong Ah , Ansoon Kim , In Bok Baek , Gun Yong Sung , Seon Hee Park
IPC分类号： G01N27/403
CPC分类号： B01L3/502715 , B01L9/527 , B01L2200/025 , B01L2300/0645 , B01L2300/0822 , G01N27/4145 , G01N27/4146
摘要： Provided is a bio-sensor chip. The bio-sensor chip includes a sensing part, a board circuit part, a channel part, and a cover. In the sensing part, a target material and a detection material interact with each other to detect the target material. The board circuit part is electrically connected to the sensing part. The channel part provides a solution material containing the target material into the sensing part. The cover is coupled to the board circuit part to cover the channel part and the sensing part.
摘要翻译：提供了一种生物传感器芯片。生物传感器芯片包括感测部分，板电路部分，通道部分和盖子。在感测部分中，目标材料和检测材料相互作用以检测目标材料。板电路部分电连接到感测部分。通道部分将包含目标材料的溶液材料提供到感测部件中。盖板连接到板电路部分以覆盖通道部分和感测部分。

17. 发明申请

US20130149216A1 DEVICE FOR STORING REAGENT AND METHOD OF DISCHARGING REAGENT THEREOF 有权
标题翻译：用于储存试剂的装置和放出试剂的方法
公开(公告)号：US20130149216A1
公开(公告)日：2013-06-13
申请号：US13528777
申请日：2012-06-20
申请人： Kwang Hyo CHUNG , Yo Han Choi , Jong Heon Yang , Chan Woo Park , Chil Seong Ah , Wan Joong Kim , Gun Yong Sung
发明人： Kwang Hyo CHUNG , Yo Han Choi , Jong Heon Yang , Chan Woo Park , Chil Seong Ah , Wan Joong Kim , Gun Yong Sung
IPC分类号： B01L3/00
CPC分类号： B01L3/0268 , B01L3/502715 , B01L3/52 , B01L2200/16 , B01L2300/0816 , B01L2400/0481 , F04B43/043
摘要： Provided are a device for storing a reagent capable of being adhered to a biochip and supplying the stored reagent to the biochip, and a method of discharging a reagent thereof. The device for storing a reagent includes an elastic film pressurizing part configured to pressurize an elastic film by magnetic force, and a reagent discharging part configured to store the reagent and discharge the reagent through an outlet by using the deformation in the elastic film due to the pressurization. According to the present invention, a magnetic force controlling device can be small-sized and the reagent can be automatically, high-precisely, and reproducibly supplied through the magnetic force control.
摘要翻译：提供了一种用于存储能够粘附到生物芯片并将储存的试剂供应到生物芯片的试剂的装置及其试剂的排出方法。用于存储试剂的装置包括：弹性膜加压部，其被配置为通过磁力对弹性膜加压;以及试剂排出部，其构造成存储试剂，并且通过使用弹性膜中的变形通过出口排出试剂，加压。根据本发明，磁力控制装置可以小型化，并且可以通过磁力控制自动，高精度地且可重复地提供试剂。

18. 发明授权

US08969099B2 Microanalysis methods and systems using field effect transistor 有权
标题翻译：微分析方法和系统采用场效应晶体管
公开(公告)号：US08969099B2
公开(公告)日：2015-03-03
申请号：US13233684
申请日：2011-09-15
申请人： Chil Seong Ah , Jong-Heon Yang , Chan Woo Park , Chang-Geun Ahn , Gun Yong Sung
发明人： Chil Seong Ah , Jong-Heon Yang , Chan Woo Park , Chang-Geun Ahn , Gun Yong Sung
IPC分类号： G01N27/00 , G01N27/414 , G01N27/327 , G01N33/543 , G01N33/53 , G01N33/58 , G01N33/553 , G01N21/65
CPC分类号： G01N33/54373 , G01N21/658 , G01N27/3278 , G01N27/414 , G01N27/4145 , G01N27/4146 , G01N33/53 , G01N33/54346 , G01N33/553 , G01N33/585 , G01N33/587
摘要： Provided is a microanalysis method and system using a Field Effect Transistor (FET). The microanalysis method includes a channel region having a receptor molecule fixed; forming a nano-particle conjugate in the channel region by supplying a sample for test and the nano-particle conjugate to the FET; growing a probe material on the channel region; and measuring a current flowing through the channel region, wherein the receptor molecule is a material that is selectively bonded to a target molecule in the sample for test.
摘要翻译：提供了一种使用场效应晶体管（FET）的微量分析方法和系统。微量分析方法包括固定有受体分子的通道区域; 通过向所述FET提供用于测试的样品和所述纳米颗粒共轭物在所述通道区域中形成纳米颗粒缀合物; 在通道区域生长探针材料; 以及测量流过所述通道区的电流，其中所述受体分子是选择性地结合到所述待测样品中的靶分子的材料。

19. 发明申请

US20120070910A1 MICROANALYSIS METHODS AND SYSTEMS USING FIELD EFFECT TRANSISTOR 有权
标题翻译：使用场效应晶体管的微观分析方法和系统
公开(公告)号：US20120070910A1
公开(公告)日：2012-03-22
申请号：US13233684
申请日：2011-09-15
申请人： Chil Seong Ah , Jong-Heon Yang , Chan Woo Park , Chang-Geun Ahn , Gun Yong Sung
发明人： Chil Seong Ah , Jong-Heon Yang , Chan Woo Park , Chang-Geun Ahn , Gun Yong Sung
IPC分类号： G01N27/00 , B82Y15/00
CPC分类号： G01N33/54373 , G01N21/658 , G01N27/3278 , G01N27/414 , G01N27/4145 , G01N27/4146 , G01N33/53 , G01N33/54346 , G01N33/553 , G01N33/585 , G01N33/587
摘要： Provided is a microanalysis method and system using a Field Effect Transistor (FET). The microanalysis method includes a channel region having a receptor molecule fixed; forming a nano-particle conjugate in the channel region by supplying a sample for test and the nano-particle conjugate to the FET; growing a probe material on the channel region; and measuring a current flowing through the channel region, wherein the receptor molecule is a material that is selectively bonded to a target molecule in the sample for test.
摘要翻译：提供了一种使用场效应晶体管（FET）的微量分析方法和系统。微量分析方法包括固定有受体分子的通道区域; 通过向所述FET提供用于测试的样品和所述纳米颗粒共轭物在所述通道区域中形成纳米颗粒缀合物; 在通道区域生长探针材料; 以及测量流过所述通道区的电流，其中所述受体分子是选择性地结合到所述待测样品中的靶分子的材料。

20. 发明授权

US08834811B2 Device for storing reagent and method of discharging reagent thereof 有权
标题翻译：储存试剂的装置及其试剂的排出方法
公开(公告)号：US08834811B2
公开(公告)日：2014-09-16
申请号：US13528777
申请日：2012-06-20
申请人： Kwang Hyo Chung , Yo Han Choi , Jong Heon Yang , Chan Woo Park , Chil Seong Ah , Wan Joong Kim , Gun Yong Sung
发明人： Kwang Hyo Chung , Yo Han Choi , Jong Heon Yang , Chan Woo Park , Chil Seong Ah , Wan Joong Kim , Gun Yong Sung
IPC分类号： B01L3/00 , B01J19/00 , F04B19/00
CPC分类号： B01L3/0268 , B01L3/502715 , B01L3/52 , B01L2200/16 , B01L2300/0816 , B01L2400/0481 , F04B43/043
摘要： Provided are a device for storing a reagent capable of being adhered to a biochip and supplying the stored reagent to the biochip, and a method of discharging a reagent thereof. The device for storing a reagent includes an elastic film pressurizing part configured to pressurize an elastic film by magnetic force, and a reagent discharging part configured to store the reagent and discharge the reagent through an outlet by using the deformation in the elastic film due to the pressurization. According to the present invention, a magnetic force controlling device can be small-sized and the reagent can be automatically, high-precisely, and reproducibly supplied through the magnetic force control.
摘要翻译：提供了一种用于存储能够粘附到生物芯片并将储存的试剂供应到生物芯片的试剂的装置及其试剂的排出方法。用于存储试剂的装置包括：弹性膜加压部，其被配置为通过磁力对弹性膜加压;以及试剂排出部，其构造成存储试剂，并且通过使用弹性膜中的变形通过出口排出试剂，加压。根据本发明，磁力控制装置可以小型化，并且可以通过磁力控制自动，高精度地且可再现地供给试剂。

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