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11. 发明授权

US07148683B2 Detection with evanescent wave probe 失效
标题翻译：用ev逝波探测器进行检测
公开(公告)号：US07148683B2
公开(公告)日：2006-12-12
申请号：US10833186
申请日：2004-04-28
申请人： Xiao Dong Xiang , Haitao Yang , Gang Wang
发明人： Xiao Dong Xiang , Haitao Yang , Gang Wang
IPC分类号： G01V3/00
CPC分类号： G01R33/60 , G01N24/00 , G01N24/006 , G01N24/08 , G01N24/10 , G01R33/345
摘要： Methods and systems for spatially resolved spin resonance detection in a sample of material are disclosed. Also disclosed are methods and systems for spatially resolved impedance measurements in a sample of material. The disclosed methods and samples can be used in screening of plurality of biological, chemical and material samples.
摘要翻译：公开了用于材料样品中空间分辨的自旋共振检测的方法和系统。还公开了用于材料样品中的空间分辨阻抗测量的方法和系统。所公开的方法和样品可用于筛选多个生物，化学和物质样品。

12. 发明申请

US20060231756A1 Analytical scanning evanescent microwave microscope and control stage 审中-公开
公开(公告)号：US20060231756A1
公开(公告)日：2006-10-19
申请号：US11454171
申请日：2006-06-14
申请人： Xiao-Dong Xiang , Chen Gao , Fred Duewer , Hai Yang
发明人： Xiao-Dong Xiang , Chen Gao , Fred Duewer , Hai Yang
IPC分类号： G01N23/00
CPC分类号： G01Q60/22
摘要： A scanning evanescent microwave microscope (SEMM) that uses near-field evanescent electromagnetic waves to probe sample properties is disclosed. The SEMM is capable of high resolution imaging and quantitative measurements of the electrical properties of the sample. The SEMM has the ability to map dielectric constant, loss tangent, conductivity, electrical impedance, and other electrical parameters of materials. Such properties are then used to provide distance control over a wide range, from to microns to nanometers, over dielectric and conductive samples for a scanned evanescent microwave probe, which enable quantitative non-contact and submicron spatial resolution topographic and electrical impedance profiling of dielectric, nonlinear dielectric and conductive materials. The invention also allows quantitative estimation of microwave impedance using signals obtained by the scanned evanescent microwave probe and quasistatic approximation modeling. The SEMM can be used to measure electrical properties of both dielectric and electrically conducting materials.

13. 发明授权

US07109706B2 Integrated EWP-STM spin resonance microscope 失效
标题翻译：综合EWP-STM自旋共振显微镜
公开(公告)号：US07109706B2
公开(公告)日：2006-09-19
申请号：US11216931
申请日：2005-08-30
申请人： Xiao-Dong Xiang , Haitao Yang
发明人： Xiao-Dong Xiang , Haitao Yang
IPC分类号： G01V3/00
CPC分类号： G01R33/60 , G01N24/10 , G01Q30/02 , G01Q60/12 , G01R33/26 , G01R33/323 , G01R33/4808
摘要： A novel spin resonance microscope is disclosed, the microscope design comprising an integrated evanescent wave probe and scanning tunneling microscope tip. The probe and tip may be either the same structure, or they may be separate structures. The integrated design allows for coherent excitation of precessing electron spin states in the sample such that spin resonance may be detected because the tunneling current is modulated by the spin resonance. Spin resonance may be affected by either adjacent nuclei, or by adjacent electrons. The present apparatus requires significantly reduced power inputs, such that the dead time of the system is short, and relaxation phenomena may be evaluated without swamping the instrument's electronics.
摘要翻译：公开了一种新型的自旋共振显微镜，显微镜设计包括集成的ev逝波探针和扫描隧道显微镜尖端。探针和尖端可以是相同的结构，或者它们可以是分离的结构。该集成设计允许在样品中进行电子自旋状态的相干激发，使得可以检测自旋共振，因为隧道电流被自旋共振调制。旋转共振可能受相邻核或相邻电子的影响。本装置需要显着降低的功率输入，使得系统的死区时间短，并且可以评估松弛现象而不会使仪器的电子元件变形。

14. 发明申请

US20060071662A1 Integrated EWP-STM spin resonance microscope 失效
公开(公告)号：US20060071662A1
公开(公告)日：2006-04-06
申请号：US11216931
申请日：2005-08-30
申请人： Xiao-Dong Xiang , Haitao Yang
发明人： Xiao-Dong Xiang , Haitao Yang
IPC分类号： G01V3/00
CPC分类号： G01R33/60 , G01N24/10 , G01Q30/02 , G01Q60/12 , G01R33/26 , G01R33/323 , G01R33/4808
摘要： A novel spin resonance microscope is disclosed, the microscope design comprising an integrated evanescent wave probe and scanning tunneling microscope tip. The probe and tip may be either the same structure, or they may be separate structures. The integrated design allows for coherent excitation of precessing electron spin states in the sample such that spin resonance may be detected because the tunneling current is modulated by the spin resonance. Spin resonance may be affected by either adjacent nuclei, or by adjacent electrons. The present apparatus requires significantly reduced power inputs, such that the dead time of the system is short, and relaxation phenomena may be evaluated without swamping the instrument's electronics.

15. 发明授权

US06924150B1 Magnetic resonance imaging contrast system 失效
标题翻译：磁共振成像对比系统
公开(公告)号：US06924150B1
公开(公告)日：2005-08-02
申请号：US10124203
申请日：2002-04-17
申请人： Xiao Dong Xiang , Gerald F. Dionne , Haitao Yang
发明人： Xiao Dong Xiang , Gerald F. Dionne , Haitao Yang
IPC分类号： G01N24/00 , G01N24/10 , A61B5/055 , A61B8/00 , G01N25/18 , G01R33/00 , G01V3/00
CPC分类号： G01N24/10 , G01N24/006 , Y10T436/24
摘要： A method for improving the magnetic resonance imaging contrast of a selected portion of a sample. A selected ferrimagnetic constituent is associated with the sample portion, by molecular or biological attachment or by some other means, so that the sample portion is distinguished from other adjacent portions of the sample that do not have the selected ferrimagnetic constituent associated therewith. Alternatively, the sample portion is suspected, but not yet confirmed, to have the selected ferrimagnetic constituent associated with it. Ferromagnetic resonance imaging is performed on the sample portion, and at least one resonance frequency ω0 of the sample portion is provided. At least one material parameter of the sample portion is measured at or near the frequency ω0, with enhanced imaging contrast relative to adjacent portions of the sample that do not have the selected ferrimagnetic constituent in association. Alternatively, the measured value is compared with a corresponding reference value for the selected ferrimagnetic constituent. If (and only if) the measured and corresponding reference values substantially agree, the selected ferrimagnetic constituent is present in association with the selected sample portion. Other parameters of the selected ferrimagnetic consituent can also be measured.
摘要翻译：一种用于改善所选部分样品的磁共振成像对比度的方法。选择的亚铁磁性成分通过分子或生物附着或通过某种其他方式与样品部分相关联，使得样品部分与样品中没有与其相关联的选择的亚铁磁性成分的其它相邻部分区分开。或者，怀疑但尚未确认样品部分具有与其相关联的所选择的亚铁磁性成分。对样品部分进行铁磁共振成像，并且提供样品部分的至少一个共振频率ω0。样品部分的至少一个材料参数在频率ω0处或附近被测量，相对于没有关联的选择的亚铁磁性成分的样品的相邻部分，具有增强的成像对比度。或者，将测量值与所选择的亚铁磁性成分的相应参考值进行比较。如果（且仅当）测量的和相应的参考值基本一致，则所选择的亚铁磁成分与选择的样品部分相关联地存在。也可以测量所选铁氧体成分的其它参数。

16. 发明授权

US06693426B1 Spatially resolved spin resonance detection 有权
标题翻译：空间分辨的自旋共振检测
公开(公告)号：US06693426B1
公开(公告)日：2004-02-17
申请号：US10071563
申请日：2002-02-09
申请人： Xiao Dong Xiang , Gang Wang , Haitao Yang , Gerald F. Dionne
发明人： Xiao Dong Xiang , Gang Wang , Haitao Yang , Gerald F. Dionne
IPC分类号： G01V300
CPC分类号： G01N24/10 , G01N24/006 , Y10T436/24
摘要： Methods for spatially resolve spin resonance detection in a sample of material, with a resolution as small as 0.5 &mgr;m-1 mm. In one embodiment, a coupler having at least one pair of degenerate orthogonal modes provides an evanescent input signal along one coupler axis to the sample, to which a magnetic field is applied, and senses a spin interaction signal along another coupler axis. In another embodiment, an evanescent input signal is applied to the sample along one of two identical transmission line resonators, and a difference of the two resonator signals provides a spin interaction signal. In another embodiment, a polarized laser beam provides an evanescent input signal to the sample, and the spin interaction signal is sensed according to a second beam polarization direction. Certain ferromagnetic or ferrimagnetic molecules, such as YIG, can be used to tag selected chemical and biological molecules, using spatially resolved spin resonance detection for interrogation.
摘要翻译：在材料样品中空间分辨自旋共振检测的方法，分辨率小至0.5 mum-1 mm。在一个实施例中，具有至少一对简并正交模式的耦合器提供沿着一个耦合器轴线向被施加磁场的样本的消逝输入信号，并且沿另一个耦合器轴线感测自旋相互作用信号。在另一个实施例中，沿着两个相同的传输线谐振器中的一个将消逝的输入信号施加到样本，并且两个谐振器信号的差提供自旋相互作用信号。在另一个实施例中，偏振激光束向样本提供消逝的输入信号，并且根据第二光束偏振方向感测自旋相互作用信号。某些铁磁或亚铁磁分子，如YIG，可用于标记选定的化学和生物分子，使用空间分辨的自旋共振检测进行询问。

17. 发明授权

US06577705B1 Combinatorial material analysis using X-ray capillary optics 失效
标题翻译：使用X射线毛细管光学的组合材料分析
公开(公告)号：US06577705B1
公开(公告)日：2003-06-10
申请号：US09824268
申请日：2001-04-02
申请人： William Chang , Xiao-Dong Xiang , Edward D. Franco
发明人： William Chang , Xiao-Dong Xiang , Edward D. Franco
IPC分类号： G01N23223
CPC分类号： G21K1/06 , G01N23/223 , G01N2223/076
摘要： Method and system for analyzing local composition and structure of a compound having one or more non-zero gradients in concentration for one or more selected constituents in a selected direction. A beam of X rays having representative energy E is received by a mono-capillary or poly-capillary device and is directed at a selected small region of the compound. A portion of the X rays is diffracted at the selected region by one or more constituents of the compound, at each of two or more diffraction angles relative to a selected surface or lattice plane(s) of the compound; and the diffracted portion of X rays for each of these diffraction angles is received and analyzed at an X-ray detector. A portion of the X rays excites fluorescence radiation that is received by a fluorescence detector to estimate the relative concentrations in a compound having two or more constituents. Fluorescence X rays and diffraction X rays can be detected at each desired translational position and rotation for a target site. As a result, a concentration map for various constituents in the compound can be prepared, together with a phase map illustrating the structure of a combinatorial compound. An X-ray detector monochromator can be removed and a capillary diameter can be reduced in some situations.
摘要翻译：用于分析具有一个或多个非零梯度的化合物的局部组成和结构的方法和系统，所述非零梯度在选定方向上的一个或多个选定成分的浓度。具有代表性能量E的X射线束由单毛细管或多毛细管装置接收并且被引导到化合物的选定的小区域。 X射线的一部分在化合物的一个或多个成分的选定区域衍射，相对于化合物的选定表面或晶格面，在两个或更多个衍射角度的每一个处; 并且在X射线检测器中接收和分析这些衍射角中的每一个的X射线的衍射部分。 X射线的一部分激发由荧光检测器接收的荧光辐射以估计具有两个或更多个成分的化合物中的相对浓度。可以在目标位置的每个所需的平移位置和旋转处检测荧光X射线和衍射X射线。结果，可以制备化合物中各种成分的浓度图，以及说明组合化合物的结构的相图。可以去除X射线检测器单色仪，并且在某些情况下可以减少毛细血管直径。

18. 发明授权

US11022574B2 Method and apparatus for rapid measurement of thermal conductivity of a thin film material 有权
公开(公告)号：US11022574B2
公开(公告)日：2021-06-01
申请号：US16365333
申请日：2019-03-26
申请人： Xiao-dong Xiang , Yuewei Wu , Xiao-ping Wang
发明人： Xiao-dong Xiang , Yuewei Wu , Xiao-ping Wang
IPC分类号： G01N25/18
摘要： The invention discloses a method and a apparatus for rapid measurement of thermal conductivity of a thin film material. The apparatus comprises a control device, a clock synchronizer, a laser, a rapid thermometer and a thermal conductivity output device; the control device and the clock synchronizer are signally connected, and the clock synchronizer is simultaneously signally connected with the laser and the rapid thermometer; in the working state, the control device sends a start signal to the clock synchronizer, and the laser and the rapid thermometer coordinately cooperate, and the laser emits laser light to the surface of the sample; at the same time, the rapid thermometer captures the surface temperature of the sample at the same specified position at different time points during the heating of the sample, and inputs the measured data into the thermal conductivity output device to obtain the thermal conductivity parameter. The apparatus of the invention has simple structure. The method of the invention is efficient and accurate. It can provide reliable parameter data for the thermal properties of various current ultra-thin semiconductor films.

19. 发明申请

US20130240188A1 METHOD AND APPARATUS FOR A DELAYED AND PROLONGED AIR COOLING CONDENSATION SYSTEM 审中-公开
标题翻译：延迟和延长空气冷却冷凝系统的方法和装置
公开(公告)号：US20130240188A1
公开(公告)日：2013-09-19
申请号：US13610661
申请日：2012-09-11
申请人： XIAO DONG XIANG , RONG ZHANG
发明人： XIAO DONG XIANG , RONG ZHANG
IPC分类号： F28D20/00
CPC分类号： F28D20/00 , F28B1/06 , F28D20/02 , F28F5/00 , F28F2265/00 , Y02E60/145
摘要： In various embodiments devices and methods are provided for an improved dry-cooling condensation system. In certain embodiments the methods involve receiving steam from a source of steam (e.g., a power plant); condensing the steam into water while transferring the latent heat of the steam into the latent heat of a thermal storage material; and dissipating the latent heat from the thermal storage material at a later time when the ambient temperature is lower than the ambient temperature at the time the steam was condensed into water.
摘要翻译：在各种实施例中，为改进的干冷缩冷凝系统提供了装置和方法。在某些实施方案中，所述方法涉及从蒸汽源（例如发电厂）接收蒸汽; 将蒸汽冷凝成水，同时将蒸汽的潜热转移到储热材料的潜热中; 并且当环境温度低于蒸汽冷凝成水时的环境温度时，在稍后的时间消散来自储热材料的潜热。

20. 发明授权

US07945335B2 Remotely RF powered conformable thermal applicators 有权
标题翻译：远程射频功率一致的热敷设器
公开(公告)号：US07945335B2
公开(公告)日：2011-05-17
申请号：US11601083
申请日：2006-11-16
申请人： Xiao-Dong Xiang , Gang Wang , Haitao Yang , Jonathan Melman , Gerald Francis Dionne
发明人： Xiao-Dong Xiang , Gang Wang , Haitao Yang , Jonathan Melman , Gerald Francis Dionne
IPC分类号： A61F2/00
CPC分类号： A61N1/406 , A61K41/0052 , A61K49/1818
摘要： Embodiments of the present invention are generally related to apparatus and methodology of thermal applicators in cancer therapy. In particular, the present embodiments are directed to a technique called “nanoparticle ferromagnetic resonance heating,” where ferromagnetic resonance heating in addition to an RF hyperthermia treatment is used to cause cell apoptosis and necrosis. An apparatus for carrying out a ferromagnetic resonance heating treatment of a tumor, comprises a volume concentration of super paramagnetic particles contained within the interior of the tumor, the concentration ranging from about 0.1 to about 1 percent; a magnetic field source configured to deliver a gradient DC magnetic field to the region of the tumor; and an energy source configured to deliver to the tumor an RF field at a frequency ranging from about 100 to 200 MHz. The apparatus of claim 1, wherein the super paramagnetic particles are selected from the group consisting of maghemite (γ-Fe2O3) based compounds, and yttrium iron garnet (Y3Fe5O12) based compounds.
摘要翻译：本发明的实施例通常涉及癌症治疗中的热敷装置的装置和方法。特别地，本实施例涉及一种称为“纳米颗粒铁磁共振加热”的技术，其中使用除RF热疗处理之外的铁磁共振加热以引起细胞凋亡和坏死。用于进行肿瘤的铁磁共振加热处理的装置包括包含在肿瘤内部的超顺磁性颗粒的体积浓度，其浓度范围为约0.1％至约1％; 磁场源，被配置为向所述肿瘤的区域递送梯度DC磁场; 以及能量源，其被配置为以大约100至200MHz的频率向所述肿瘤递送RF场。 2.根据权利要求1所述的装置，其中所述超顺磁性粒子选自由以磁赤铁矿（γ-Fe2O3）为基础的化合物和基于钇铁石榴石（Y 3 Fe 5 O 12）的化合物组成的组。

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