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1. 发明授权

US08049996B2 Coherent spin valve and related devices 失效
标题翻译：相干自旋阀及相关装置
公开(公告)号：US08049996B2
公开(公告)日：2011-11-01
申请号：US12236327
申请日：2008-09-23
申请人： Haitao Yang , Xiao-Dong Xiang
发明人： Haitao Yang , Xiao-Dong Xiang
IPC分类号： G11B5/39 , H01L29/82
CPC分类号： G06N99/002 , B82Y10/00 , B82Y25/00 , G11B5/3903 , H01F10/1936 , H01F10/3268 , H01F10/329 , Y10S977/933 , Y10T428/1107
摘要： Embodiments of the present invention are directed toward the field of spintronics, and in particular, systems and devices capable of performing spin coherent quantum logic operations. The inventive spin valve comprises two ferromagnetic electrode layers, and a non-magnetic conducting layer positioned therebetween. An external magnetic field B0 is applied in the Z direction, such that the two electrode layers are each magnetized in a direction substantially parallel to the external magnetic field. Rather than attempting to change the magnetization of one of the ferromagnetic layers, as is the case in prior art technologies, it is the direction of the electron spin that is manipulated in the present embodiments while the electron is traveling through the middle, nonmagnetic layer. One of the ferromagnetic electrodes may be the tip of a scanning tunneling microscope (STM). This configuration may further comprise a bias voltage source connected between the STM tip and the other ferromagnetic electrode, such that a spin polarized tunneling current is conducted between the two.
摘要翻译：本发明的实施例涉及自旋电子学领域，特别是能够执行自相关量子逻辑运算的系统和装置。本发明的自旋阀包括两个铁磁电极层和位于它们之间的非磁性导电层。在Z方向上施加外部磁场B0，使得两个电极层在大致平行于外部磁场的方向上各自被磁化。与现有技术中的情况一样，不是试图改变铁磁层之一的磁化，而是在电子行进通过中间非磁性层时在本实施例中操纵的电子自旋的方向。铁磁电极之一可以是扫描隧道显微镜（STM）的尖端。该配置还可以包括连接在STM尖端和另一个铁磁电极之间的偏置电压源，使得在两者之间进行自旋极化隧穿电流。

2. 发明授权

US07704923B2 High throughput screening of catalysts using spin resonance 失效
标题翻译：使用自旋共振的催化剂的高通量筛选
公开(公告)号：US07704923B2
公开(公告)日：2010-04-27
申请号：US11299034
申请日：2005-12-08
申请人： Xiao-Dong Xiang , Haitao Yang , Gang Wang , Jonathan Melman
发明人： Xiao-Dong Xiang , Haitao Yang , Gang Wang , Jonathan Melman
IPC分类号： C40B30/00
CPC分类号： G01N33/542 , G01N24/087 , G01N24/088 , G01N2500/00 , G01R33/323 , G01R33/34 , G01R33/34053 , G01R33/3456 , G01R33/44 , G01R33/46 , G01R33/48 , G01R33/60 , G06F19/16
摘要： High throughput screening of catalyst libraries may be performed using spin resonance techniques, and an evanescent wave probe developed by the present inventors. The probe may operate using either nuclear magnetic resonance or electron spin resonance techniques. In one configuration, a scanning evanescent wave spin resonance probe is used in conjunction with a library of catalysts or other materials, and localized detection of spin resonance is carried out at each library address. In another configuration, the evanescent wave probe is used in a micro-reactor array assay.
摘要翻译：催化剂文库的高通量筛选可以使用自旋共振技术和由本发明人开发的ev逝波探针进行。探针可以使用核磁共振或电子自旋共振技术进行操作。在一种配置中，扫描ev逝波自旋共振探针与催化剂或其他材料的文库结合使用，并且在每个文库地址进行自旋共振的局部检测。在另一种配置中，ev逝波探针用于微反应器阵列测定。

3. 发明授权

US07276902B1 Detection with evanescent wave probe 失效
公开(公告)号：US07276902B1
公开(公告)日：2007-10-02
申请号：US11542891
申请日：2006-10-03
申请人： Xiao-Dong Xiang , Haitao Yang , Gang Wang
发明人： Xiao-Dong Xiang , Haitao Yang , Gang Wang
IPC分类号： G01V3/00
CPC分类号： G01R33/60 , G01N24/00 , G01N24/006 , G01N24/08 , G01N24/10 , G01R33/345
摘要： Methods and systems for spatially resolved spin resonance detection in a sample of material are disclosed. Also disclosed are methods and systems for spatially resolved impedance measurements in a sample of material. The disclosed methods and samples can be used in screening of plurality of biological, chemical and material samples.

4. 发明申请

US20060183002A1 Coherent spin valve and related devices 有权
标题翻译：相干自旋阀及相关装置
公开(公告)号：US20060183002A1
公开(公告)日：2006-08-17
申请号：US11241292
申请日：2005-09-29
申请人： Haitao Yang , Xiao-Dong Xiang
发明人： Haitao Yang , Xiao-Dong Xiang
IPC分类号： G11B5/39
CPC分类号： G06N99/002 , B82Y10/00 , B82Y25/00 , G11B5/3903 , H01F10/1936 , H01F10/3268 , H01F10/329 , Y10S977/933 , Y10T428/1107
摘要： Embodiments of the present invention are directed toward the field of spintronics, and in particular, systems and devices capable of performing spin coherent quantum logic operations. The inventive spin valve comprises two ferromagnetic electrode layers, and a non-magnetic conducting layer positioned therebetween. An external magnetic field {right arrow over (B)}0 is applied in the Z direction, such that the two electrode layers are each magnetized in a direction substantially parallel to the external magnetic field. Rather than attempting to change the magnetization of one of the ferromagnetic layers, as is the case in prior art technologies, it is the direction of the electron spin that is manipulated in the present embodiments while the electron is traveling through the middle, nonmagnetic layer. One of the ferromagnetic electrodes may be the tip of a scanning tunneling microscope (STM). This configuration may further comprise a bias voltage source connected between the STM tip and the other ferromagnetic electrode, such that a spin polarized tunneling current is conducted between the two.
摘要翻译：本发明的实施例涉及自旋电子学领域，特别是能够执行自相关量子逻辑运算的系统和装置。本发明的自旋阀包括两个铁磁电极层和位于它们之间的非磁性导电层。在Z方向上施加外部磁场（向右箭头（B 0 ），使得两个电极层各自在基本上平行于外部磁场的方向上磁化，而不是试图改变如现有技术中的一种铁磁层的磁化，它是在电子行进通过中间非磁性层时在本实施例中操纵的电子自旋的方向，一个铁磁电极可以是扫描隧道显微镜（STM）的尖端，该配置还可以包括连接在STM尖端和另一个铁磁电极之间的偏置电压源，使得在两者之间进行自旋极化隧道电流。

5. 发明申请

US20060160136A1 High throughput screening of catalysts using spin resonance 失效
标题翻译：使用自旋共振的催化剂的高通量筛选
公开(公告)号：US20060160136A1
公开(公告)日：2006-07-20
申请号：US11299034
申请日：2005-12-08
申请人： Xiao-Dong Xiang , Haitao Yang , Gang Wang , Jonathan Melman
发明人： Xiao-Dong Xiang , Haitao Yang , Gang Wang , Jonathan Melman
IPC分类号： C40B40/02 , C40B50/02
CPC分类号： G01N33/542 , G01N24/087 , G01N24/088 , G01N2500/00 , G01R33/323 , G01R33/34 , G01R33/34053 , G01R33/3456 , G01R33/44 , G01R33/46 , G01R33/48 , G01R33/60 , G06F19/16
摘要： High throughput screening of catalyst libraries may be performed using spin resonance techniques, and an evanescent wave probe developed by the present inventors. The probe may operate using either nuclear magnetic resonance or electron spin resonance techniques. In one configuration, a scanning evanescent wave spin resonance probe is used in conjunction with a library of catalysts or other materials, and localized detection of spin resonance is carried out at each library address. In another configuration, the evanescent wave probe is used in a micro-reactor array assay.
摘要翻译：可以使用自旋共振技术和由本发明人开发的ev逝波探针来进行催化剂文库的高通量筛选。探针可以使用核磁共振或电子自旋共振技术进行操作。在一种配置中，扫描ev逝波自旋共振探针与催化剂或其他材料的文库结合使用，并且在每个文库地址进行自旋共振的局部检测。在另一种配置中，ev逝波探针用于微反应器阵列测定。

6. 发明申请

US20060125465A1 Evanescent microwave probe with enhanced resolution and sensitivity 失效
标题翻译：渐近微波探头具有更高的分辨率和灵敏度
公开(公告)号：US20060125465A1
公开(公告)日：2006-06-15
申请号：US11180045
申请日：2005-07-11
申请人： Xiao-Dong Xiang , Haitao Yang , Gang Wang
发明人： Xiao-Dong Xiang , Haitao Yang , Gang Wang
IPC分类号： G01R31/02
CPC分类号： G01Q10/065 , G01Q60/22
摘要： Novel systems of an evanescent microwave probe (EWP) are disclosed, which enable measurements of physical properties of a sample with enhanced sensitivity and resolution, simultaneously. In one embodiment, new shielding features are added to the probe (which may be of either a sharpened tip or loop configuration) to reduce the effects of residual far field radiation, while maintaining the probe section that extends beyond the shielding aperture of the resonator. To further increase the sensitivity of the instrument, an automatic gain-controlled active feedback loop system may be added to the probe resonator to form a self-oscillator. This new active circuit feature significantly increases the effective Q of the resonator probe, enhancing the sensitivity of both the frequency and Q measurement.
摘要翻译：公开了一种ev逝微波探测器（EWP）的新型系统，可同时测量具有增强灵敏度和分辨率的样品的物理性能。在一个实施例中，将新的屏蔽特征添加到探头（其可以是尖锐的尖端或环形配置）以减少残余远场辐射的影响，同时保持探头部分延伸超出谐振器的屏蔽孔径。为了进一步提高仪器的灵敏度，可以将自动增益控制的主动反馈回路系统添加到探头谐振器中以形成自振荡器。这种新的有源电路特征显着增加了谐振器探头的有效Q，提高了频率和Q测量的灵敏度。

7. 发明授权

US07945335B2 Remotely RF powered conformable thermal applicators 有权
标题翻译：远程射频功率一致的热敷设器
公开(公告)号：US07945335B2
公开(公告)日：2011-05-17
申请号：US11601083
申请日：2006-11-16
申请人： Xiao-Dong Xiang , Gang Wang , Haitao Yang , Jonathan Melman , Gerald Francis Dionne
发明人： Xiao-Dong Xiang , Gang Wang , Haitao Yang , Jonathan Melman , Gerald Francis Dionne
IPC分类号： A61F2/00
CPC分类号： A61N1/406 , A61K41/0052 , A61K49/1818
摘要： Embodiments of the present invention are generally related to apparatus and methodology of thermal applicators in cancer therapy. In particular, the present embodiments are directed to a technique called “nanoparticle ferromagnetic resonance heating,” where ferromagnetic resonance heating in addition to an RF hyperthermia treatment is used to cause cell apoptosis and necrosis. An apparatus for carrying out a ferromagnetic resonance heating treatment of a tumor, comprises a volume concentration of super paramagnetic particles contained within the interior of the tumor, the concentration ranging from about 0.1 to about 1 percent; a magnetic field source configured to deliver a gradient DC magnetic field to the region of the tumor; and an energy source configured to deliver to the tumor an RF field at a frequency ranging from about 100 to 200 MHz. The apparatus of claim 1, wherein the super paramagnetic particles are selected from the group consisting of maghemite (γ-Fe2O3) based compounds, and yttrium iron garnet (Y3Fe5O12) based compounds.
摘要翻译：本发明的实施例通常涉及癌症治疗中的热敷装置的装置和方法。特别地，本实施例涉及一种称为“纳米颗粒铁磁共振加热”的技术，其中使用除RF热疗处理之外的铁磁共振加热以引起细胞凋亡和坏死。用于进行肿瘤的铁磁共振加热处理的装置包括包含在肿瘤内部的超顺磁性颗粒的体积浓度，其浓度范围为约0.1％至约1％; 磁场源，被配置为向所述肿瘤的区域递送梯度DC磁场; 以及能量源，其被配置为以大约100至200MHz的频率向所述肿瘤递送RF场。 2.根据权利要求1所述的装置，其中所述超顺磁性粒子选自由以磁赤铁矿（γ-Fe2O3）为基础的化合物和基于钇铁石榴石（Y 3 Fe 5 O 12）的化合物组成的组。

8. 发明授权

US07271574B2 Evanescent microwave probe with enhanced resolution and sensitivity 失效
标题翻译：渐近微波探头具有更高的分辨率和灵敏度
公开(公告)号：US07271574B2
公开(公告)日：2007-09-18
申请号：US11180045
申请日：2005-07-11
申请人： Xiao-Dong Xiang , Haitao Yang , Gang Wang
发明人： Xiao-Dong Xiang , Haitao Yang , Gang Wang
IPC分类号： G01R31/02
CPC分类号： G01Q10/065 , G01Q60/22
摘要： Novel systems of an evanescent microwave probe (EWP) are disclosed, which enable measurements of physical properties of a sample with enhanced sensitivity and resolution, simultaneously. In one embodiment, new shielding features are added to the probe (which may be of either a sharpened tip or loop configuration) to reduce the effects of residual far field radiation, while maintaining the probe section that extends beyond the shielding aperture of the resonator. To further increase the sensitivity of the instrument, an automatic gain-controlled active feedback loop system may be added to the probe resonator to form a self-oscillator. This new active circuit feature significantly increases the effective Q of the resonator probe, enhancing the sensitivity of both the frequency and Q measurement.
摘要翻译：公开了一种ev逝微波探测器（EWP）的新型系统，可同时测量具有增强灵敏度和分辨率的样品的物理性能。在一个实施例中，将新的屏蔽特征添加到探头（其可以是尖锐的尖端或环形配置）以减少残余远场辐射的影响，同时保持探头部分延伸超出谐振器的屏蔽孔径。为了进一步提高仪器的灵敏度，可以将自动增益控制的主动反馈回路系统添加到探头谐振器中以形成自振荡器。这种新的有源电路特征显着增加了谐振器探头的有效Q，提高了频率和Q测量的灵敏度。

9. 发明授权

US06946835B1 Spatially resolved spin resonance detection 失效
标题翻译：空间分辨的自旋共振检测
公开(公告)号：US06946835B1
公开(公告)日：2005-09-20
申请号：US10759745
申请日：2004-01-16
申请人： Xiao-Dong Xiang , Gang Wang , Haitao Yang
发明人： Xiao-Dong Xiang , Gang Wang , Haitao Yang
IPC分类号： G01N24/00 , G01R33/345 , G01V3/00
CPC分类号： G01N24/00 , G01R33/345
摘要： Methods for spatially resolved spin resonance detection in a sample of material, with a resolution as small as 0.5 μ m –1 mm. In one embodiment, a coupler having at least one pair of degenerate orthogonal modes provides an evanescent input signal along one coupler axis to the sample, to which a magnetic field is applied, and senses a spin interaction signal along another coupler axis. In another embodiment, an evanescent input signal is applied to the sample along one of two identical transmission line resonators, and a difference of the two resonator signals provides a spin interaction signal. In another embodiment, a polarized laser beam provides an evanescent input signal to the sample, and the spin interaction signal is sensed according to a second beam polarization direction. Certain ferromagnetic or ferrimagnetic molecules, such as YIG, can be used to tag selected chemical and biological molecules, using spatially resolved spin resonance detection for interrogation.
摘要翻译：在材料样品中进行空间分辨自旋共振检测的方法，分辨率小至0.5μm-1 mm。在一个实施例中，具有至少一对简并正交模式的耦合器提供沿着一个耦合器轴线向被施加磁场的样本的消逝输入信号，并且沿另一个耦合器轴线感测自旋相互作用信号。在另一个实施例中，沿着两个相同的传输线谐振器中的一个将消逝的输入信号施加到样本，并且两个谐振器信号的差提供自旋相互作用信号。在另一个实施例中，偏振激光束向样本提供消逝的输入信号，并且根据第二光束偏振方向感测自旋相互作用信号。某些铁磁或亚铁磁分子，如YIG，可用于标记选定的化学和生物分子，使用空间分辨的自旋共振检测进行询问。

10. 发明授权

US07109706B2 Integrated EWP-STM spin resonance microscope 失效
标题翻译：综合EWP-STM自旋共振显微镜
公开(公告)号：US07109706B2
公开(公告)日：2006-09-19
申请号：US11216931
申请日：2005-08-30
申请人： Xiao-Dong Xiang , Haitao Yang
发明人： Xiao-Dong Xiang , Haitao Yang
IPC分类号： G01V3/00
CPC分类号： G01R33/60 , G01N24/10 , G01Q30/02 , G01Q60/12 , G01R33/26 , G01R33/323 , G01R33/4808
摘要： A novel spin resonance microscope is disclosed, the microscope design comprising an integrated evanescent wave probe and scanning tunneling microscope tip. The probe and tip may be either the same structure, or they may be separate structures. The integrated design allows for coherent excitation of precessing electron spin states in the sample such that spin resonance may be detected because the tunneling current is modulated by the spin resonance. Spin resonance may be affected by either adjacent nuclei, or by adjacent electrons. The present apparatus requires significantly reduced power inputs, such that the dead time of the system is short, and relaxation phenomena may be evaluated without swamping the instrument's electronics.
摘要翻译：公开了一种新型的自旋共振显微镜，显微镜设计包括集成的ev逝波探针和扫描隧道显微镜尖端。探针和尖端可以是相同的结构，或者它们可以是分离的结构。该集成设计允许在样品中进行电子自旋状态的相干激发，使得可以检测自旋共振，因为隧道电流被自旋共振调制。旋转共振可能受相邻核或相邻电子的影响。本装置需要显着降低的功率输入，使得系统的死区时间短，并且可以评估松弛现象而不会使仪器的电子元件变形。

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