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111. 发明申请

US20160340634A1 CULTURING DEVICE 审中-公开
标题翻译：文化装置
公开(公告)号：US20160340634A1
公开(公告)日：2016-11-24
申请号：US15228210
申请日：2016-08-04
申请人： TOKYO ELECTRON LIMITED
发明人： Kiyoshi MORI
IPC分类号： C12M1/00 , C12M1/12 , C12M1/02
CPC分类号： C12M41/14 , C12M23/22 , C12M37/00 , C12M41/20
摘要： A culturing device includes an incubator part. The incubator part includes an internal housing, a mounting part installed within the internal housing and configured to mount thereon a container which stores cells, a plurality of heating parts installed within the internal housing and disposed in a symmetrical relationship with respect to an axis of rotational symmetry extending in an up-down direction, a gas circulation part installed in an upper central position within the internal housing and configured to draw a gas existing within the internal housing and to discharge the gas thus drawn; and a diffusion member configured to diffuse the gas discharged from the gas circulation part within the internal housing in a symmetrical relationship with respect to the axis of rotational symmetry.
摘要翻译：培养装置包括培养箱部分。培养箱部分包括内部壳体，安装部分安装在内部壳体内并且构造成在其上安装储存细胞的容器，多个加热部件安装在内部壳体内并且相对于旋转轴线对称地设置对称性在上下方向上延伸，气体循环部件安装在内部壳体内的上部中心位置，并且构造成抽吸存在于内部壳体内的气体并排出如此拉出的气体; 以及扩散构件，其被构造成以相对于所述旋转对称轴线对称的关系将从所述内部壳体内的所述气体循环部排出的气体扩散。

112. 发明申请

US20160272932A1 Cell culture apparatus with mechanical and temperature control 审中-公开
标题翻译：具有机械和温度控制的细胞培养装置
公开(公告)号：US20160272932A1
公开(公告)日：2016-09-22
申请号：US14880712
申请日：2015-10-12
申请人： Thomas Allen Precht
发明人： Thomas Allen Precht
IPC分类号： C12M1/00 , C12M1/02 , C12M3/06
CPC分类号： C12M41/14 , C12M23/12 , C12M27/16 , C12M41/12 , C12M41/22
摘要： A cell culture controlling device is able to precisely control a cell culture's temperature and physical position. It contains a thermoelectric unit, a heat transfer medium, a controller, a pitch actuation unit, a medium temperature sensor, an ambient temperature sensor, a position sensor, a user interface, a powder supply and an alarm. The cell culture controlling device is able to maintain a cell culture temperature within a range from −10° C. to 70° C. with an increment of 1° C. and maintain the physical position of a cell culture container within a range from 0° to 45° with an increment of 1°. In this device, the thermoelectric unit is a Peltier solid state cooler, which allows an easy and accurate temperature control.
摘要翻译：细胞培养控制装置能够精确地控制细胞培养物的温度和物理位置。它包含热电单元，传热介质，控制器，俯仰驱动单元，介质温度传感器，环境温度传感器，位置传感器，用户接口，粉末供应和报警器。细胞培养控制装置能够将细胞培养温度保持在-10℃至70℃的范围内，增量为1℃，并将细胞培养容器的物理位置维持在0 °至45°，增量为1°。在该装置中，热电单元是珀尔帖固态冷却器，其允许容易且准确的温度控制。

113. 发明授权

US09422515B2 Fermentation method and apparatus adapted for the method 有权
标题翻译：适用于该方法的发酵方法和装置
公开(公告)号：US09422515B2
公开(公告)日：2016-08-23
申请号：US13255662
申请日：2009-03-18
申请人： Remo Crosato
发明人： Remo Crosato
IPC分类号： C12G1/022 , C12G1/02 , C12F3/02 , C12M1/107 , C12M1/02 , C12M1/00
CPC分类号： C12G1/02 , C12F3/02 , C12M23/36 , C12M27/00 , C12M29/24
摘要： A method for treating a vegetable product in the form of crushed material includes the steps of (i) storing the crushed material in a first vat to let it ferment and form a cap of solid parts floating on a liquid mass therein; (ii) connecting a second vat to the first one to gather in it the gaseous products generated due to fermentation; (iii) isolating the two vats; (iv) reducing the gaseous pressure in the first vat; (v) connecting the second vat to the first at a point beneath the cap so that, due to the differential pressure between the two vats, spontaneous racking of gaseous products in the liquid mass occurs, in such a manner that rising they get into contact with the cap.
摘要翻译：用于处理粉碎材料的植物产品的方法包括以下步骤：（i）将破碎的材料储存在第一槽中，使其发酵并形成浮在其上的液体块上的固体部分的盖; （ii）将第二桶连接到第一桶以收集由于发酵而产生的气态产品; （iii）分离两个桶; （iv）降低第一桶中的气压; （v）在盖子下方的一点将第二桶连接到第一桶，使得由于两个桶之间的压差，发生液体物质中的气态产物的自发的排放，以使其上升接触的方式与帽。

114. 发明授权

US09409806B2 System and method for thermophilic anaerobic digester process 有权
标题翻译：用于嗜热厌氧消化器的系统和方法
公开(公告)号：US09409806B2
公开(公告)日：2016-08-09
申请号：US14036747
申请日：2013-09-25
申请人： Renewable Energy Alternatives, LLC
发明人： Robert Knoop
IPC分类号： C02F3/28 , C02F11/04 , B09B3/00 , C12M1/107 , C12M1/06 , C12M1/00 , C12M1/02 , C12M3/00 , C12M3/04 , C02F103/20 , C02F103/22 , C02F103/28 , C02F103/32
CPC分类号： C02F3/28 , B09B3/00 , C02F3/284 , C02F11/04 , C02F2103/20 , C02F2103/22 , C02F2103/28 , C02F2103/32 , C02F2103/325 , C02F2209/005 , C02F2209/02 , C02F2209/06 , C02F2209/10 , C02F2301/106 , C12M21/04 , C12M23/48 , C12M27/06 , C12M27/10 , C12M27/20 , C12M41/18 , C12M45/20 , Y02E50/343 , Y02W10/12
摘要： A new approach is proposed that contemplates systems and methods to support an environmentally-friendly, “green” thermophilic anaerobic digestion system. The system includes a thermophilic anaerobic digester as well as various independent modular anaerobic units to generate bio-methane from certain organic energy sources, including but not limited to, among other things, green municipal waste, restaurant and organic waste and effluents from industries such as breweries, grocery stores, food processing plants, granaries, wineries, pulp and paper mills, ethanol and biodiesel plants, fat and animal rendering, agricultural field crops, organic sludge accumulation within lagoons and waterways, marine organic matter and animal manure.
摘要翻译：提出了一种新方法，其中考虑了支持环保型“绿色”嗜热厌氧消化系统的系统和方法。该系统包括嗜热厌氧消化器以及各种独立的模块化厌氧单元，以从某些有机能源产生生物甲烷，包括但不限于绿色城市废物，餐馆和有机废物以及来自行业的废水啤酒厂，杂货店，食品加工厂，粮仓，酿酒厂，造纸厂，乙醇和生物柴油厂，脂肪和动物饲养，农田作物，泻湖和水道内的有机污泥积聚，海洋有机物和动物粪便。

115. 发明授权

US09382511B2 Bioreactor outlet air conditioning systems and associated methods 有权
标题翻译：生物反应器出口空调系统及相关方法
公开(公告)号：US09382511B2
公开(公告)日：2016-07-05
申请号：US13660475
申请日：2012-10-25
申请人： TAP Biosystems (PHC) Limited
发明人： Adrian Neil Bargh
IPC分类号： C12M1/34 , C12M1/02 , C12M1/00 , C12M3/00 , C12M1/12
CPC分类号： C12M29/26 , C12M23/28 , C12M23/38 , C12M23/44 , C12M23/46 , C12M23/48 , C12M37/02 , C12M41/12 , C12M41/18 , C12M41/22 , C12M41/26 , C12M41/44 , C12M41/48 , G01N35/0099
摘要： A bioreactor outlet air conditioning system (10) has a bioreactor vessel (100) and a heat exchanger. The heat exchanger has a fluid flow path (196) from a headspace (108) in the vessel for venting air from the vessel, and a temperature control element (300) in thermal contact with the fluid flow path (196). The fluid flow path (196) may be defined by a disposable portion of the bioreactor vessel (100). A method of controlling evaporation within a bioreactor vessel (100), dependent on the required evaporation rate, adjusts the temperature of the temperature control element (300) to control the rate of evaporation of the liquid media (106) from the vessel (100), and may include monitoring fluids in the fluid flow path (196) to detect at least water content of the fluids exiting the vessel to adjust the temperature and control the rate of evaporation dependent on the detected water content levels.
摘要翻译：生物反应器出口空气调节系统（10）具有生物反应器容器（100）和热交换器。热交换器具有来自容器中的顶部空间（108）的流体流动路径（196），用于从容器排出空气，以及与流体流动路径（196）热接触的温度控制元件（300）。流体流动路径（196）可以由生物反应器容器（100）的一次性部分限定。根据所需的蒸发速率控制生物反应器容器（100）内的蒸发的方法，调节温度控制元件（300）的温度以控制来自容器（100）的液体介质（106）的蒸发速率，，并且可以包括监测流体流动路径（196）中的流体，以至少检测离开容器的流体的水含量，以调节温度并根据检测到的含水量控制蒸发速率。

116. 发明申请

US20160177344A1 METHOD AND APPARATUS FOR CO2 SEQUESTRATION 有权
标题翻译： CO2序列的方法和装置
公开(公告)号：US20160177344A1
公开(公告)日：2016-06-23
申请号：US14975584
申请日：2015-12-18
申请人： California Institute of Technology , University of Southern California , Hebrew University of Jerusalem
发明人： Adam Vinay Subhas , William Berelson , Nick Everett Rollins , Jess Firey Adkins , Jonathan Erez
IPC分类号： C12P7/40 , C12M1/02 , C12M1/00
CPC分类号： C12P7/40 , B01D53/346 , B01D53/62 , B01D53/77 , B01D53/8671 , B01D2251/606 , B01D2251/90 , B01D2255/804 , C12M23/58 , C12M27/00 , C12M29/00 , C12M29/04 , C12M29/18 , Y02C10/04 , Y02P20/152 , Y02P20/59
摘要： Processes, methods, and apparatus for carbon sequestration utilizing catalysis schemes configured to provide high concentrations of hydrated CO2 in proximity with a sequestration agent are provided. Reactants are combined with catalyst such that at least two regions of controlled catalytic activity form encompassing at least the interface between a sequestration agent and an aqueous solution containing dissolved CO2. Suitable reactants include various sequestration agents, catalyst, and carbon dioxide dissolved in an aqueous solution (seawater, for example). Possible products include bicarbonate and metal cations.
摘要翻译：提供了利用催化方案进行碳封存的方法和方法，该方案被配置为提供高浓度的水合CO 2与螯合剂附近。将催化剂与催化剂结合使得至少两个具有受控催化活性的区域形成至少包含螯合剂和含有溶解的CO 2的水溶液之间的界面。合适的反应物包括溶解在水溶液（例如海水）中的各种螯合剂，催化剂和二氧化碳。可能的产品包括碳酸氢盐和金属阳离子。

117. 发明申请

US20160177249A1 Reactor System 有权
标题翻译：反应堆系统
公开(公告)号：US20160177249A1
公开(公告)日：2016-06-23
申请号：US14909141
申请日：2014-07-30
申请人： ANAERO TECHNOLOGY LTD
发明人： Ray Middleton , Edgar Blanco , Robin Proctor
IPC分类号： C12M1/00 , F04B23/06 , B01J19/24 , C12M1/107 , B01J4/02 , B01J4/00 , F04B9/02 , C12M1/02
CPC分类号： C12M29/00 , B01J4/007 , B01J4/02 , B01J19/0046 , B01J19/1856 , B01J19/24 , B01J19/2445 , B01J2219/00011 , B01J2219/00058 , B01J2219/00069 , B01J2219/00094 , B01J2219/00164 , B01J2219/00166 , B01J2219/00186 , B01J2219/00353 , B01J2219/00376 , B01J2219/24 , C12M21/04 , C12M23/36 , C12M27/00 , C12M41/18 , F04B9/02 , F04B23/06
摘要： An apparatus is described which includes at least one reactor, at least one linear piston pump, the or each piston pump including a tube, a piston and an arm coupled to the piston, the or each piston pump arranged to inject feedstock to a respective reactor, a beam or plate coupled to the arm(s) of the piston pump(s) configured to linearly drive the piston(s) and a linear actuator for driving the beam or plate. The piston pump has a volume of at least 50 milliliters and an output port having a diameter of at least 5 mm.
摘要翻译：描述了一种装置，其包括至少一个反应器，至少一个直线活塞泵，所述或每个活塞泵包括管，活塞和联接到活塞的臂，所述或每个活塞泵被配置成将原料喷射到相应的反应器联接到所述活塞泵的一个或多个臂的梁或板被构造成直线驱动所述活塞和用于驱动所述梁或板的线性致动器。活塞泵的体积至少为50毫升，输出口的直径至少为5毫米。

118. 发明申请

US20160168529A1 METHOD FOR PRODUCING CELL CONCENTRATE, AND CELL SUSPENSION TREATMENT SYSTEM 审中-公开
标题翻译：生产细胞浓度的方法和细胞悬浮液处理系统
公开(公告)号：US20160168529A1
公开(公告)日：2016-06-16
申请号：US14906320
申请日：2014-07-16
申请人： KANEKA CORPORATION
发明人： Shuhei TANIGUCHI , Nobuyoshi UMEDA , Takaaki SAKASHITA , Hiroshi SAKURAI
IPC分类号： C12M1/34 , C12M1/26 , C12M1/02 , C12M1/36
CPC分类号： C12M41/46 , A61M1/0218 , A61M1/0281 , A61M1/34 , A61M1/3403 , A61M1/3406 , A61M1/3496 , A61M1/3603 , A61M1/3621 , A61M1/3626 , A61M1/3643 , A61M1/3644 , A61M1/3692 , A61M2205/3389 , A61M2205/3393 , C12M27/00 , C12M33/04 , C12M41/44 , C12M41/48 , C12M47/02
摘要： In a method for producing a cell concentrate using a cell suspension treatment system including a storage container of a cell suspension, which has a solution inlet port, a circulation outlet port, and a circulation inlet port, a cell suspension treatment device for concentrating the cell suspension by separating liquid from the cell suspension by filtration, the device including a container having a cell suspension introduction port, a cell suspension lead-out port, and a filtrate outlet, which is filled with a hollow fiber separation membrane, a circulation circuit for concentrating the cell suspension while circulating the cell suspension between the storage container and the cell suspension treatment device, a collection container of a cell concentrate obtained by concentration, a collection path for feeding the cell concentrate to the collection container, an injection path for injecting a solution into the solution inlet port of the storage container, and a detecting unit.
摘要翻译：在使用细胞悬液处理系统的细胞浓缩物的制造方法中，所述细胞悬浮液处理系统包括具有溶液入口，循环出口和循环引入口的细胞悬液的储存容器，用于将细胞浓缩的细胞悬液处理装置通过过滤从液体悬浮液中分离液体的悬浮液，该装置包括一个容器，该容器具有填充有中空纤维分离膜的细胞悬液引入口，细胞悬液引出口和滤液出口，循环回路在细胞悬浮液在储存容器和细胞悬浮液处理装置之间循环的同时使细胞悬浮液浓缩，通过浓缩获得的细胞浓缩物的收集容器，用于将细胞浓缩物送入收集容器的收集路径，溶液进入储存容器的溶液入口，以及检测单元。

119. 发明授权

US09340763B2 Temperature controlling surfaces and support structures 有权
标题翻译：温度控制表面和支撑结构
公开(公告)号：US09340763B2
公开(公告)日：2016-05-17
申请号：US13691998
申请日：2012-12-03
申请人： GE HEALTHCARE BIO-SCIENCES CORP.
发明人： Richard L. Damren , Thomas Erdenberger , Colin R. Tuohey , Joseph D. Crowell , Parrish M. Galliher , Kenneth P. Clapp , Peter A. Mitchell
IPC分类号： B01J8/00 , C12M1/00 , C12M1/02 , B01F15/00 , B01J19/00 , B01J19/18 , F28F3/12 , F28F13/06 , F28D1/06 , F28D1/02 , B01J19/24 , B65D30/08 , F16L11/04 , F28D1/047 , F28F9/013 , F28D7/02 , F28D21/00 , F28F13/00
CPC分类号： C12M41/24 , B01F15/0085 , B01J19/006 , B01J19/18 , B01J19/24 , B01J2219/0002 , B01J2219/00081 , B01J2219/00085 , B01J2219/0009 , B01J2219/00094 , B01J2219/00765 , B01J2219/00768 , B01J2219/24 , B65D31/02 , C12M23/14 , C12M23/26 , C12M23/28 , C12M27/20 , C12M41/18 , F16L11/04 , F28D1/0213 , F28D1/047 , F28D1/06 , F28D7/024 , F28D7/026 , F28D2021/0022 , F28D2021/0077 , F28D2021/0078 , F28F3/12 , F28F9/0131 , F28F13/06 , F28F2009/228 , F28F2013/006 , F28F2255/02
摘要： A heat exchange module for use in a chemical, pharmaceutical or biological reactor system can include a body configured to be disposed in the reactor system having an inner replaceable reactant container is disclosed. The body can further include at least one thermally conductive surface adapted to contact the inner replaceable reactant container to facilitate heat transfer. Furthermore, the heat exchange module can include a heat exchanger disposed within the module body and can include a fluid circulation path through which a heat exchange fluid can be circulated.
摘要翻译：用于化学，药物或生物反应器系统的热交换模块可以包括被配置为设置在具有内部可更换反应物容器的反应器系统中的主体。主体还可包括适于接触内部可更换反应物容器以促进热传递的至少一个导热表面。此外，热交换模块可以包括设置在模块体内的热交换器，并且可以包括可以循环热交换流体的流体循环路径。

120. 发明授权

US09315768B2 Biological microfluidics chip and related methods 有权
标题翻译：生物微流体芯片及相关方法
公开(公告)号：US09315768B2
公开(公告)日：2016-04-19
申请号：US13378924
申请日：2010-06-15
申请人： Elwin Xander Vrouwe , Eric Marijn Wielhouwer , Johannes Oonk , Marinus Bernardus Olde Riekerink , Michael Keith Richardson
发明人： Elwin Xander Vrouwe , Eric Marijn Wielhouwer , Johannes Oonk , Marinus Bernardus Olde Riekerink , Michael Keith Richardson
IPC分类号： C12M1/34 , C12M3/00 , C12M1/32 , B01L3/00 , C12M3/06 , C12M1/02
CPC分类号： C12M23/12 , B01L3/5027 , B01L3/50851 , B01L3/50853 , B01L2300/0829 , B01L2300/0877 , B01L2300/185 , C12M23/16 , C12M41/18
摘要： A biological microfluidics chip comprising a substrate, a microfluidic inlet port defining an opening in a surface of the substrate, and a microfluidic outlet port defining an opening in a surface of the substrate. The biological microfluidics chip also comprises a plurality of wells extending from a top surface of the substrate, wherein each well is bounded by one or more walls, and an inlet opening and an outlet opening are provided in a wall of each of the plurality of wells. An inlet microfluidic channel is provided in the substrate to connect the microfluidic inlet port to each of the inlet openings in the walls of the wells, and an outlet microfluidic channel is provided in the substrate to connect each of the outlet openings in the walls of the wells to the microfluidic outlet port.
摘要翻译：一种生物微流体芯片，包括衬底，限定衬底表面中的开口的微流体入口端口和限定衬底表面中的开口的微流体出口端口。生物微流体芯片还包括从基底的顶表面延伸的多个孔，其中每个孔由一个或多个壁限定，并且在多个孔中的每一个的壁中设置入口和出口。入口微流体通道设置在衬底中，以将微流体入口端口连接到孔的壁中的每个入口开口，并且在衬底中设置出口微流体通道，以将每个出口开口连接到井到微流体出口。

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