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101. 发明申请

US20100297334A1 Variable Stiffness Catheter Assembly 有权
标题翻译：可变刚度导管组件
公开(公告)号：US20100297334A1
公开(公告)日：2010-11-25
申请号：US12847703
申请日：2010-07-30
申请人： Jan Weber
发明人： Jan Weber
IPC分类号： A61L33/00 , B23P17/04
CPC分类号： A61M25/0054 , A61M25/0009 , A61M25/0045 , A61M25/0053 , A61M25/0138 , A61M25/0158 , A61M25/09 , A61M25/1006 , A61M2025/0024 , A61M2025/0035 , A61M2025/0039 , A61M2025/0058 , A61M2025/0063 , A61M2025/0915 , A61M2025/09175 , Y10T29/49826
摘要： A catheter comprising an outer shaft comprising a first section of electroactive polymer. The first section of electroactive polymer affecting either the flexibility of the catheter or the steerability of the catheter.
摘要翻译：一种导管，其包括包含电活性聚合物的第一部分的外轴。电活性聚合物的第一部分影响导管的柔性或导管的可操纵性。

102. 发明授权

US07838806B2 Resonator with adjustable capacitor for medical device 失效
标题翻译：谐振器用于医疗设备的可调电容器
公开(公告)号：US07838806B2
公开(公告)日：2010-11-23
申请号：US11982548
申请日：2007-11-02
申请人： Jan Weber
发明人： Jan Weber
IPC分类号： H05B6/36
CPC分类号： G01R33/286 , A61B5/055 , A61F2/82 , G01R33/3628 , Y10T29/49117
摘要： An apparatus, system and method of a resonator device with an adjustable capacitor for allowing the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system. The resonator device includes an inductor coil, a conductive member, a sleeve having first and second sockets that receive at least portions of the inductor coil and the conductive member as electrodes to provide a capacitor structure. Dielectric material can be positioned between at least the first and second sockets, where changes in the cross sectional area defined by the induction coil cause changes in the capacitance value (C) as one or more of the electrodes move within the socket. Changes in the inductance and the capacitance values allow for the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system.
摘要翻译：具有可调电容器的谐振器装置的装置，系统和方法，用于允许谐振器装置的谐振频率（F）继续与MRI系统的拉莫尔频率匹配。谐振器装置包括电感线圈，导电构件，具有第一和第二插座的套筒，该套管至少容纳电感器线圈和导电构件的至少一部分作为电极以提供电容器结构。介电材料可以位于至少第一和第二插座之间，其中由感应线圈限定的横截面积的变化引起电容值（C）的变化，因为一个或多个电极在插座内移动。电感和电容值的变化允许谐振器装置的谐振频率（F）继续与MRI系统的拉莫尔频率匹配。

103. 发明申请

US20100286678A1 Medical Devices 有权
标题翻译：医疗设备
公开(公告)号：US20100286678A1
公开(公告)日：2010-11-11
申请号：US12838980
申请日：2010-07-19
申请人： Jan Weber , John M. Hokanson , John H. Chen
发明人： Jan Weber , John M. Hokanson , John H. Chen
IPC分类号： A61B18/02 , A61B18/04 , A61M25/10
CPC分类号： A61M25/104 , A61F7/123 , A61L29/126 , A61M25/10 , B82Y5/00 , B82Y30/00
摘要： Medical systems and methods including balloons having nanotubes are disclosed. In some embodiments, a medical system includes an elongated shaft, and an expandable balloon carried by the shaft and including nanotubes. The medical system is capable of cooling the balloon to less than about 37° C. In some embodiments, a method includes providing a medical device having an elongated shaft, and an expandable balloon carried by the elongated shaft and including nanotubes; and cooling the balloon to less than about 37° C.
摘要翻译：公开了包括具有纳米管的气囊的医疗系统和方法。在一些实施例中，医疗系统包括细长轴和由轴承载并包括纳米管的可膨胀气囊。医疗系统能够将球囊冷却到小于约37℃。在一些实施例中，一种方法包括提供具有细长轴的医疗装置和由细长轴承载并包括纳米管的可膨胀气囊; 并将气球冷却至小于约37℃。

104. 发明申请

US20100280452A1 MEDICAL DEVICES HAVING MULTIPLE LAYERS 有权
公开(公告)号：US20100280452A1
公开(公告)日：2010-11-04
申请号：US12835157
申请日：2010-07-13
申请人： John Jianhua Chen , Jan Weber
发明人： John Jianhua Chen , Jan Weber
IPC分类号： A61M25/10 , A61K9/14 , A61K31/19 , A61K31/662 , A61K31/255 , A61K31/135 , A61K31/13 , A61K31/713 , A61K38/00 , A61P29/00 , A61P35/00 , A61P23/00 , A61P7/02 , A61P3/06
CPC分类号： A61L29/085 , A61L29/16 , A61L2300/608 , A61L2300/624
摘要： Described herein are medical devices which are configured for implantation or insertion into a subject, preferably a mammalian subject. The medical devices contain one or more multilayer regions, which contain: (a) one or more (typically a plurality of) charged nanoparticle layers and (b) one or more (typically a plurality of) charged polyelectroyte layers. Such multilayers have a number of desirable attributes, including high strength, non-compliance, and flexibility. Also described herein are methods of making such devices.

105. 发明授权

US07799050B2 Devices and methods for magnetically manipulating intravascular devices 失效
标题翻译：用于磁操作血管内装置的装置和方法
公开(公告)号：US07799050B2
公开(公告)日：2010-09-21
申请号：US10838988
申请日：2004-05-05
申请人： Joseph Hensley , Thomas E. Broome , Jan Weber
发明人： Joseph Hensley , Thomas E. Broome , Jan Weber
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2210/009 , A61F2230/005 , A61F2230/0067
摘要： Devices and methods for magnetically centering and retrieving intravascular devices within a body lumen are disclosed. An intravascular filter in accordance with an illustrative embodiment may comprise an expandable filter structure having at least one magnetic element formed therein. The intravascular filter can be retrieved using a magnetic retrieval device that includes a magnetic retrieval mechanism for centering and retrieving the intravascular filter.
摘要翻译：公开了用于磁体定心和取回体腔内的血管内装置的装置和方法。根据说明性实施例的血管内过滤器可以包括其中形成有至少一个磁性元件的可膨胀过滤器结构。血管内过滤器可以使用包括用于对中和取回血管内过滤器的磁回收机构的磁回收装置来取回。

106. 发明申请

US20100145437A1 Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface 审中-公开
标题翻译：支架设计允许药物的扩展释放和/或增强的聚合物粘附到OD表面
公开(公告)号：US20100145437A1
公开(公告)日：2010-06-10
申请号：US12706881
申请日：2010-02-17
申请人： Timothy S. Girton , Jeffrey S. Lindquist , David M. Knapp , Matt Heidner , Daniel Gregorich , Umang Anand , Peter Edelman , Matthew J. Miller , Raed Rizq , Jan Weber , Tracee Eidenschink , John J. Chen , Jaykeep Y. Kokate , Aparna Bhave , Kent D. Harrison , Graig L. Kveen , Benjamin Arcand , Michael Kuchling
发明人： Timothy S. Girton , Jeffrey S. Lindquist , David M. Knapp , Matt Heidner , Daniel Gregorich , Umang Anand , Peter Edelman , Matthew J. Miller , Raed Rizq , Jan Weber , Tracee Eidenschink , John J. Chen , Jaykeep Y. Kokate , Aparna Bhave , Kent D. Harrison , Graig L. Kveen , Benjamin Arcand , Michael Kuchling
IPC分类号： A61F2/82
CPC分类号： A61F2/91 , A61F2210/0076 , A61F2220/0066 , A61F2220/0083 , A61F2250/0067 , A61F2250/0068
摘要： The invention is directed to mechanisms and methods that reduce the delamination of a therapeutic agent from a stent. The mechanisms include holes (channels, wells, and other hole configurations), protrusions, sintered metal cores, clamps/staples, pins, and stainless steel shields.
摘要翻译：本发明涉及减少治疗剂从支架分层的机制和方法。这些机构包括孔（通道，孔和其他孔构造），突起，烧结金属芯，夹/钉，销和不锈钢屏蔽。

107. 发明申请

US20100131004A1 METHODS AND APPARATUS FOR EMBOLI REMOVAL 审中-公开
标题翻译：用于去除手术的方法和装置
公开(公告)号：US20100131004A1
公开(公告)日：2010-05-27
申请号：US12695941
申请日：2010-01-28
申请人： Jan Weber , Tracee E.J. Eidenschink , David J. Sogard , Joel M. WasDyke , Thomas J. Holman
发明人： Jan Weber , Tracee E.J. Eidenschink , David J. Sogard , Joel M. WasDyke , Thomas J. Holman
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2/24 , A61F2/2493 , A61F2/86 , A61F2002/018 , A61F2002/068 , A61F2230/0006 , A61F2230/0067
摘要： Improved methods and apparatus for capturing emboli and subsequently removing or immobilizing the captured emboli are described. Emboli can be captured within a blood vessel and can be withdrawn to a position exterior to the blood vessel. Some filters can remain within a blood vessel yet direct emboli to a position exterior to the blood vessel.
摘要翻译：描述了用于捕获栓塞以及随后去除或固定所捕获的栓塞的改进的方法和装置。栓塞可以在血管内捕获并且可以撤回到血管外部的位置。一些过滤器可以保留在血管内，但是直接栓塞到血管外部的位置。

108. 发明授权

US07725160B2 Tunable MRI enhancing device 有权
标题翻译：可调MRI增强装置
公开(公告)号：US07725160B2
公开(公告)日：2010-05-25
申请号：US10216988
申请日：2002-08-12
申请人： Jan Weber
发明人： Jan Weber
IPC分类号： A61B5/05
CPC分类号： G01R33/285 , G01R33/3628
摘要： The present invention is directed to an MRI enhancing device deployable in a body. In one embodiment, the MRI enhancing device is formed of a wire loop and a capacitor that is at least partially formed by the wire used in forming the wire loop.
摘要翻译：本发明涉及一种可在体内展开的MRI增强装置。在一个实施例中，MRI增强装置由线环和至少部分地由形成线环的电线形成的电容器形成。

109. 发明申请

US20100057188A1 ENDOPROSTHESES WITH POROUS REGIONS AND NON-POLYMERIC COATING 审中-公开
标题翻译：具有多孔区域和非聚合涂层的内部结构
公开(公告)号：US20100057188A1
公开(公告)日：2010-03-04
申请号：US12200530
申请日：2008-08-28
申请人： Jan Weber
发明人： Jan Weber
IPC分类号： A61F2/06
CPC分类号： A61L31/022 , A61L31/028 , A61L31/146 , A61L31/16 , A61L2300/608
摘要： Endoprostheses include an endoprosthesis wall that includes a surface layer that includes a metallic material and that defines a plurality of pores. A therapeutic agent fills one or more pores of the surface layer and a non-polymeric coating, covers the therapeutic agent in the one or more pores. The endoprostheses can, for example, deliver a therapeutic agent, such as a drug, in a controlled manner over an extended period of time.
摘要翻译：内假体包括内置假体壁，其包括包含金属材料并限定多个孔的表面层。治疗剂填充表面层的一个或多个孔和非聚合物涂层，覆盖一个或多个孔中的治疗剂。内用假体可以例如以长期的控制方式递送诸如药物的治疗剂。

110. 发明申请

US20090259300A1 Medical Devices With an Interlocking Coating and Methods of Making the Same 审中-公开
标题翻译：具有联锁涂层的医疗设备及其制造方法
公开(公告)号：US20090259300A1
公开(公告)日：2009-10-15
申请号：US12421107
申请日：2009-04-09
申请人： William E. Dorogy, JR. , Raed Rizq , Ben Arcand , Steve Kangas , Jan Weber
发明人： William E. Dorogy, JR. , Raed Rizq , Ben Arcand , Steve Kangas , Jan Weber
IPC分类号： A61F2/06
CPC分类号： A61L31/16 , A61L31/086 , A61L31/146 , A61L2300/416 , A61L2300/606
摘要： Disclosed herein are medical devices, such as intravascular stents, for delivering a therapeutic agent to the body tissue of a patient, and a method for making such medical devices. More particularly, the medical devices have a coating that includes a polymer that adheres to the surface of the medical device so that the coating is able to resist damage during loading, deployment and implantation.
摘要翻译：本文公开了用于将治疗剂递送到患者的身体组织的医疗装置，例如血管内支架，以及用于制造这种医疗装置的方法。更具体地，医疗装置具有涂层，其包括粘附到医疗装置的表面的聚合物，使得涂层能够在加载，展开和植入期间抵抗损伤。

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