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    • 99. 发明申请
    • POROUS POLYMERIC MATERIAL WITH CROSS-LINKABLE WETTING AGENT
    • 具有交联润湿剂的多孔聚合材料
    • US20100048755A1
    • 2010-02-25
    • US12515264
    • 2007-11-17
    • Edwin Pei Yong ChowJackie Y. Ying
    • Edwin Pei Yong ChowJackie Y. Ying
    • C08G63/00C08J9/00C08G73/06
    • C08J9/283A61F9/0008A61L27/16A61L27/50A61L27/56C08B37/0021C08B37/0072C08F290/10C08J2207/10C08J2333/06C08L51/02G02B1/043C08L2666/02
    • A porous material is provided which comprises a transparent polymer matrix defining interconnected pores and a wetting agent. At least a portion of the wetting agent is cross-linked with the polymer matrix. A process for forming a porous polymeric material is also provided. A bicontinuous microemulsion comprising water, a wetting agent, a monomer, and a surfactant copolymerizable with the monomer is polymerized, to form a polymer defining interconnected pores. The wetting agent comprises a cross-linkable wetting agent such that after polymerization, at least a portion of the cross-linkable wetting agent is cross-linked with the polymer. The wetting agent may comprise acrylated hyaluronic acid (AHA) such as methacrylated hyaluronic acid (MeHA). The wetting agent may also comprise a hyaluronic acid (HA). The wetting agent may include an unbonded portion that this releasable from the material. A contact lens may be made from the porous material.
    • 提供一种多孔材料,其包括限定互连孔的透明聚合物基质和润湿剂。 润湿剂的至少一部分与聚合物基质交联。 还提供了一种形成多孔聚合物材料的方法。 将包含水,润湿剂,单体和可与单体共聚的表面活性剂的双连续微乳液聚合,形成限定互连孔的聚合物。 润湿剂包括可交联的润湿剂,使得在聚合后,至少一部分可交联润湿剂与聚合物交联。 润湿剂可以包括丙烯酸酯化透明质酸(AHA),例如甲基丙烯酸酯化透明质酸(MeHA)。 润湿剂还可以包含透明质酸(HA)。 润湿剂可以包括可从材料中释放的未粘合部分。 隐形眼镜可以由多孔材料制成。