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    • 5. 发明授权
    • Oxygenator
    • 氧气机
    • US08968652B2
    • 2015-03-03
    • US13208932
    • 2011-08-12
    • Mitsuaki Ogihara
    • Mitsuaki Ogihara
    • A61M1/00A61M37/00A61M1/16A61M1/36
    • A61M1/1698A61M1/3627A61M2205/366A61M2205/7527
    • An oxygenator that inhibits or prevents bubbles in blood from exiting through a blood outlet includes an oxygenator part which performs gas exchange on blood and a heat exchanging part which performs heat exchange on the blood. The oxygenators part has a housing that is generally in a rectangular parallelepiped form, with a hollow fiber membrane bundle positioned in the housing. The hollow fiber membrane bundle is formed by a multiplicity of hollow fiber membranes adapted to perform gas exchange. Blood flows along a blood passage comprised of gaps between the hollow fiber membranes and contacts the surface of the hollow fiber membranes where gas exchange occurs with gas flowing through the lumens of the hollow fiber membranes. In addition, a filter member is arranged on a downstream side of the hollow fiber membrane bundle so that bubbles present in the blood are caught by the filter member.
    • 抑制或防止血液中的气泡离开血液出口的氧合器包括对血液进行气体交换的氧合器部分和对血液进行热交换的热交换部。 氧合器部分具有通常为长方体形状的壳体,中空纤维膜束定位在壳体中。 中空纤维膜束由适于进行气体交换的多个中空纤维膜形成。 血液沿着由中空纤维膜之间的间隙组成的血液通道流动,并与中空纤维膜的表面接触,其中气体交换发生在流过中空纤维膜的内腔的气体中。 此外,过滤构件设置在中空纤维膜束的下游侧,使得存在于血液中的气泡被过滤构件卡住。
    • 10. 发明申请
    • MACROPOROUS FILTRATION MEMBRANE
    • 大面积过滤膜
    • US20140039415A1
    • 2014-02-06
    • US14110947
    • 2012-03-29
    • Frank SchneiderMartin CzernikWalter StrippRamona Tatsch
    • Frank SchneiderMartin CzernikWalter StrippRamona Tatsch
    • B01D71/68A61M5/165
    • A61M5/165A61M5/1411A61M5/16804A61M2005/1652A61M2005/1657A61M2205/7527B01D67/0009B01D69/02B01D69/06B01D71/68B01D2325/02B01D2325/021B01D2325/023B01D2325/026B01D2325/24
    • Hydrophilic flat-sheet membrane based on a hydrophobic first polymer from the group consisting of aromatic sulfone polymers and a hydrophilic second polymer, wherein the membrane has a thickness in the range between 30 and 200 μm, a first and a second surface and a supporting layer having a three-dimensional sponge-like network structure, wherein the supporting layer has a first cover layer on the side thereof facing the first surface and a second cover layer on the side thereof facing the second surface, which cover layers are formed integrally with the supporting layer, and wherein the first and second surfaces have approximately oval or circular openings which penetrate the first and second cover layers, respectively, and are connected to the supporting layer, wherein the average diameter of the openings in the surfaces differ by a factor of less than 2, wherein the three-dimensional network structure of the supporting layer is made up of thick branches and a continuous pore system, and the predominant proportion of the branches have a diameter of at least 0.5 μm at the thinnest point thereof and wherein the pores in the supporting layer are larger than the openings in the surfaces.
    • 基于由芳族砜聚合物和亲水性第二聚合物组成的组的疏水性第一聚合物的亲水性平片膜,其中所述膜具有在30和200μm之间的厚度,第一和第二表面和支撑层 具有三维海绵状网状结构,其中所述支撑层在其面向所述第一表面的一侧具有第一覆盖层,并且在其面向所述第二表面的一侧上具有第二覆盖层,所述覆盖层与所述第二覆盖层一体形成 并且其中所述第一表面和第二表面具有分别穿过所述第一和第二覆盖层的大致椭圆形或圆形开口,并且连接到所述支撑层,其中所述表面中的开口的平均直径相差 小于2,其中支撑层的三维网状结构由厚的分支和连续的孔系统组成 ,并且分支的主要比例在其最薄点具有至少0.5μm的直径,并且其中支撑层中的孔比表面中的开口大。