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91. 发明授权

US5382596A Substituted 2-aminotetralins 失效
标题翻译：取代的2-氨基鸟嘌呤
公开(公告)号：US5382596A
公开(公告)日：1995-01-17
申请号：US102436
申请日：1993-08-05
申请人： Mark C. Sleevi , Gevork Minaskanian , L. Meredith Moses
发明人： Mark C. Sleevi , Gevork Minaskanian , L. Meredith Moses
IPC分类号： C07D317/58 , A61K31/215 , A61K31/34 , A61K31/341 , A61K31/35 , A61K31/351 , A61K31/357 , A61K31/36 , A61P25/00 , A61P27/02 , A61P27/06 , C07C217/08 , C07C217/12 , C07C219/26 , C07D307/14 , C07D309/04 , C07D309/06 , C07D317/70 , A61K31/135 , C07D211/00 , C07D315/00
CPC分类号： C07D309/06 , C07C217/08 , C07C217/12 , C07C219/26 , C07D307/14 , C07D309/04 , C07D317/70 , C07C2101/02 , C07C2101/04 , C07C2101/08 , C07C2102/10
摘要： Optically active or racemic compounds represented by the formula ##STR1## where R.sub.2 is OA and R.sub.3 is selected from the group consisting of H and OA; where A is H or is selected from the group consisting of hydrocarbyl radicals comprising between 1 and 3 carbon atoms, as well as ##STR2## with the proviso that when R.sub.3 is OA, then R.sub.2 and R.sub.3 may be bonded together to form the group R.sub.4 is selected from the group consisting of alkyl and aromatic residues having from 1 to 20, preferably from 1 to 12, carbon atoms, for example, alkyl, optionally substituted with aromatic residues, and aromatic residues optionally substituted with alkyl radicals; n is an integer from 1 to 4; R.sub.5 is an unbranched alkyl chain comprising from 1 and 3 carbon atoms or a cyclopropylmethyl radical; R.sub.1 is alkoxy, cycloalkoxy and a cyclic ether of the formula ##STR3## where m is an integer from 3 to 5; with the proviso that when R.sub.1 is alkoxy, then R.sub.3 cannot be H; and pharmaceutically-acceptable salts thereof.These compounds are useful for alleviating Parkinsonism, glaucoma, hyperprolactinemia and for inducing weight loss in mammals.
摘要翻译：由式“IMAGE”表示的光学活性或外消旋化合物，其中R2是OA，R3选自H和OA; 其中A为H或选自包含1至3个碳原子的烃基，以及，条件是当R3为OA时，则R2和R3可以键合在一起，图像> R 4选自具有1至20个，优选1至12个碳原子的烷基和芳族残基，例如任选被芳族残基取代的烷基和任选被烷基取代的芳族残基; n是1至4的整数; R5是包含1和3个碳原子的无支链烷基链或环丙基甲基; R1是烷氧基，环烷氧基和式为IMAMA的环醚，其中m是3至5的整数; 条件是当R1为烷氧基时，则R3不能为H; 及其药学上可接受的盐。这些化合物可用于缓解帕金森综合征，青光眼，高催乳素血症和诱导哺乳动物的体重减轻。

92. 发明授权

US5380914A Fungicidal 2-methoximinocarboxylic esters 失效
标题翻译：杀真菌2-甲氧基羧酸酯
公开(公告)号：US5380914A
公开(公告)日：1995-01-10
申请号：US163495
申请日：1993-12-07
申请人： Wolfgang Kramer , Dieter Berg , Heinz-Wilhelm Dehne , Stefan Dutzmann
发明人： Wolfgang Kramer , Dieter Berg , Heinz-Wilhelm Dehne , Stefan Dutzmann
IPC分类号： A01N37/50 , A01N37/52 , A01N39/02 , A01N41/10 , A01N43/16 , A01N43/30 , A01N43/36 , A01N43/40 , A01N43/54 , A01N43/60 , A01N43/66 , A01N43/82 , A01N43/824 , A01N43/832 , A01N47/02 , C07C249/06 , C07C249/08 , C07C249/12 , C07C251/40 , C07C251/48 , C07C253/30 , C07C255/54 , C07C255/57 , C07C259/14 , C07C315/04 , C07C317/22 , C07C317/44 , C07C319/20 , C07C323/19 , C07C323/62 , C07D207/26 , C07D207/27 , C07D213/79 , C07D239/34 , C07D239/60 , C07D241/46 , C07D251/20 , C07D251/26 , C07D263/38 , C07D285/12 , C07D285/135 , C07D285/14 , C07D311/58 , C07D311/76 , C07D317/54 , C07D317/62 , C07C229/34
CPC分类号： C07D207/27 , A01N37/50 , A01N37/52 , A01N43/16 , A01N43/30 , A01N43/36 , A01N43/40 , A01N43/54 , A01N43/60 , A01N43/66 , A01N43/82 , C07C251/40 , C07C251/48 , C07C255/54 , C07C317/22 , C07C317/44 , C07C323/19 , C07C323/62 , C07D213/79 , C07D239/34 , C07D239/60 , C07D251/20 , C07D251/26 , C07D263/38 , C07D285/135 , C07D285/14 , C07D311/58 , C07D317/62 , C07C2101/02 , C07C2101/14 , C07C2102/10
摘要： Fungicidal new 2-methoximinocarboxylic esters of the general formula (I) ##STR1## in which Ar represents one of the radicals ##STR2## A represents one of the radicals ##STR3## where Y represents one of the radicals ##STR4## n represents the number 0 or 1, R represents alkyl, halogenoalkyl, alkenyl, halogenoalkenyl, or represents optionally substituted cycloalkyl, or represents optionally substituted aryl or represents optionally substituted heteroaryl, and, moreover, in the event that n is 0, also represents halogen, andX.sup.1, X.sup.2, X.sup.3 and X.sup.4 independently of one another in each case represent hydrogen, halogen, hydroxyl or methoxy, but where, in the event that X.sup.2 represents bromine, X.sup.3 does not simultaneously represent hydroxyl or methoxy.
摘要翻译：其中Ar表示基团之一的具有通式（I）的化合物（I）的杀真菌剂新的2-甲氧基羧酸酯代表其中一个基团，其中Y代表基团之一， SO2CH2; O; CHCH或CH2CH2，n表示数字0或1，R表示烷基，卤代烷基，烯基，卤代烯基或表示任意取代的环烷基，或表示任意取代的芳基或表示任选取代的杂芳基，此外，在n为0的情况下，也表示卤素，X1，X2，X3和X4各自独立地表示氢，卤素，羟基或甲氧基，但在X2表示溴的情况下，X3不同时表示羟基或甲氧基。

93. 发明授权

US5371268A Ortho-substituted benzyl esters of cyclopropanecarboxylic acids 失效
标题翻译：正丙基取代的环丙烷羧酸的苄基酯
公开(公告)号：US5371268A
公开(公告)日：1994-12-06
申请号：US209358
申请日：1994-03-14
申请人： Franz Schuetz , Hubert Sauter , Norbert Goetz , Jochen Wild , Hans-Josef Wolf , Reinhard Doetzer , Gisela Lorenz , Eberhard Ammermann , Christoph Kuenast , Uwe Kardorff
发明人： Franz Schuetz , Hubert Sauter , Norbert Goetz , Jochen Wild , Hans-Josef Wolf , Reinhard Doetzer , Gisela Lorenz , Eberhard Ammermann , Christoph Kuenast , Uwe Kardorff
IPC分类号： A01N55/00 , A01N37/36 , A01N37/50 , A01N53/00 , A01N53/06 , C07C69/74 , C07C69/743 , C07C69/753 , C07C69/757 , C07C251/48 , C07C255/46 , C07F7/08 , C07C69/76
CPC分类号： C07C69/743 , A01N37/36 , A01N37/50 , A01N53/00 , C07C251/48 , C07C69/74 , C07C2101/02
摘要： Ortho-substituted benzyl esters of cyclopropanecarboxylic acids I ##STR1## where X is N or CH and A is one of the following cyclopropane radicals: ##STR2## where R.sup.1 is CN, C.sub.2 -C.sub.8 -alkyl, CF.sub.3, C.sub.3 -C.sub.8 -alkenyl, (C.sub.1 -C.sub.4 -alkoxycarbonyl, unsubstituted or substituted phenyl-C.sub.1 -C.sub.6 -alkyl or phenyl-C.sub.3 -C.sub.6 -alkenyl, ethoxyphenyl, 2- or 3-bromophenyl, 2- or 4-trifluoromethylphenyl, 2,4- or 2,6-difluorophenyl, 2-fluoro-6-chlorophenyl, 2,4- or 2,6-dimethylphenyl, 2,3,6-trichlorophenyl or trimethylsilyl, R.sup.2 is H or halogen, R.sup.3 is unsubstituted or substituted phenyl, R.sup.4 is CH.sub.3 or halogen and Hal is halogen, with the proviso that X is CH when R.sup.1 is CF.sub.3 or trimethylsilyl, are suitable as fungicides and for controlling pests.
摘要翻译：其中X是N或CH，A是以下环丙烷基之一：其中R 1是CN，C 2 -C 8 - 烷基，CF 3，C 3 -C 6环烷基， C 8 - 烯基，（C 1 -C 4 - 烷氧基羰基，未取代或取代的苯基-C 1 -C 6烷基或苯基-C 3 -C 6 - 烯基，乙氧基苯基，2-或3-溴苯基，2-或4-三氟甲基苯基，或2,6-二氟苯基，2-氟-6-氯苯基，2,4-或2,6-二甲基苯基，2,3,6-三氯苯基或三甲基甲硅烷基，R 2为H或卤素，R 3为未取代或取代的苯基，R 4 是CH3或卤素，Hal为卤素，条件是当R1为CF3或X为三甲基甲硅烷基时X为CH，适合作为杀真菌剂和防治害虫。

94. 发明授权

US5364849A 1-[3 or 4-[1-[4-piperazinyl]]-2 arylpropionyl or butryl]-heterocyclic derivatives 失效
标题翻译： 1- [3或4- [1- [4-哌嗪基]] - 2芳基丙酰基或丁基] - 杂环衍生物
公开(公告)号：US5364849A
公开(公告)日：1994-11-15
申请号：US911996
申请日：1992-07-10
申请人： Ian A. Cliffe
发明人： Ian A. Cliffe
IPC分类号： C07D205/04 , C07D221/20 , C07D239/42 , C07D295/084 , C07D295/088 , C07D295/125 , C07D295/13 , C07D295/145 , C07D295/15 , C07D295/185 , C07D319/20 , A61K31/55 , A61K31/535 , C07D401/00 , C07D403/02
CPC分类号： C07D221/20 , C07D205/04 , C07D239/42 , C07D295/088 , C07D295/092 , C07D295/125 , C07D295/13 , C07D295/145 , C07D295/15 , C07D295/185 , C07D319/20 , C07C2101/02 , C07C2101/08 , C07C2101/14 , C07C2101/18 , C07C2101/20
摘要： Piperazine derivatives of formula ##STR1## and their pharmaceutically acceptable acid addition salts are disclosed. In the formula n is 1 or 2, R is hydrogen or lower alkyl, R.sup.1 is an aryl or nitrogen containing heteroaryl radical, R.sup.2 is hydrogen or lower alkyl, R.sup.3 is aryl, C.sub.4-8 alkyl or aryl(lower)alkyl and X is a functionalised group of specified meaning. The compounds exhibit activity as 5-HT.sub.1A antagonists and can be used, into alia, for the treatment of CNS disorders, such as anxiety.
摘要翻译：公开了式“IMAGE”的哌嗪衍生物及其药学上可接受的酸加成盐。式中n为1或2，R为氢或低级烷基，R1为芳基或含氮杂芳基，R2为氢或低级烷基，R3为芳基，C4-8烷基或芳基（低级）烷基，X为一个具有指定意义的功能组。该化合物表现出作为5-HT1A拮抗剂的活性，并且可以用于治疗中枢神经系统疾病如焦虑症。

95. 发明授权

US5359080A Yellow dye-forming coupler and silver halide color photographic material containing same 失效
标题翻译：黄色染料成色剂和卤化银彩色照相材料
公开(公告)号：US5359080A
公开(公告)日：1994-10-25
申请号：US17447
申请日：1993-02-12
申请人： Yoshio Shimura , Hidetoshi Kobayashi , Yasuhiro Yoshioka
发明人： Yoshio Shimura , Hidetoshi Kobayashi , Yasuhiro Yoshioka
IPC分类号： C07C235/80 , C07D233/66 , G03C7/305 , C07D233/78 , C07C233/14 , C07C311/08
CPC分类号： C07D233/66 , C07C235/80 , G03C7/30535 , C07C2101/02
摘要： There is disclosed an acylacetamide-type yellow coupler having an acyl group represented by formula (I) and a silver halide color photographic material containing same. ##STR1## wherein R.sub.1 represents a monovalent group, Q represents a group of non-metallic atoms required to form together with the C a substituted or unsubstituted 3- to 5-membered cyclic hydrocarbon group or a substituted or unsubstituted 3- to 5-membered heterocyclic group having in the group at least one hetero atom selected from a group consisting of N, 0, S, and P, provided that R.sub.1 is not a hydrogen atom and does not bond to Q to form a ring.
摘要翻译：公开了具有由式（I）表示的酰基的酰基乙酰胺型黄色成色剂和含有它的卤化银彩色感光材料。式（I）其中R1表示一价基团，Q表示与C一起形成取代或未取代的3至5元环状烃基所需的一组非金属原子或取代或未取代的3- 至少一个选自N，O，S和P的杂原子的5元杂环基团，条件是R 1不是氢原子并且不与Q键合形成环。

96. 发明授权

US5332754A Naphthyloxazolidone derivatives 失效
标题翻译：萘氧基唑烷酮衍生物
公开(公告)号：US5332754A
公开(公告)日：1994-07-26
申请号：US961873
申请日：1992-10-15
申请人： Hideo Nakai , Koichiro Yamada , Sumihiro Nomura , Mamoru Matsumoto , Hiroshi Iwata
发明人： Hideo Nakai , Koichiro Yamada , Sumihiro Nomura , Mamoru Matsumoto , Hiroshi Iwata
IPC分类号： C07D263/20 , A61K31/42 , A61K31/421 , A61P25/24 , A61P25/26 , C07C215/10 , C07C215/14 , C07C215/86 , C07C217/94 , C07C219/34 , C07C235/20 , C07C255/58 , C07C271/30 , C07C271/44 , C07C309/47 , C07C309/51 , C07C311/38 , C07C311/39 , C07C311/47 , C07C317/18 , C07C323/12 , C07D263/24 , C07D307/12 , C07D413/06 , C07D413/10
CPC分类号： C07D263/20 , C07C217/94 , C07D263/24 , C07C2101/02
摘要： A naphthyloxazolidone derivative of the formula: ##STR1## wherein R.sup.1 is hydrogen atom, hydroxy group, nitro group, amino group, sulfo group, aminosulfonyl group, a lower alkenyloxy group, a lower alkynyloxy group, a mono or di(lower alkyl)aminocarbonyloxy group, a lower alkanoyloxy group or a lower alkoxy group which may have a substituent selected from an aryl group, a cycloalkyl group, an oxygen-containing heteromonocyclic group, hydroxy group, a lower alkoxy group, cyano group, a di(lower alkyl)amino group, aminocarbonyl group, a lower alkoxycarbonyl group, a lower alkanoyloxy group, a lower alkylthio group, a lower alkylsulfinyl group and a lower alkylsulfonyl group; R.sup.2 is hydroxy group, a lower alkoxy group, a lower alkylsulfonyloxy group, triazo group or an amino group which may have a substituent selected from a lower alkyl group and a lower alkanoyl group, and a pharmaceutically acceptable salt thereof are disclosed. Said derivative and a pharmaceutically acceptable salt thereof are useful as an antidepressant.
摘要翻译：其中R1是氢原子，羟基，硝基，氨基，磺基，氨基磺酰基，低级链烯氧基，低级炔氧基，一或二（低级烷基）氨基羰基氧基基团，可以具有选自芳基，环烷基，含氧杂单环基，羟基，低级烷氧基，氰基，二（低级烷基）取代基的低级烷酰氧基或低级烷氧基，氨基，氨基羰基，低级烷氧基羰基，低级烷酰氧基，低级烷硫基，低级烷基亚磺酰基和低级烷基磺酰基; R2是羟基，低级烷氧基，低级烷基磺酰氧基，三唑基或可以具有选自低级烷基和低级烷酰基的取代基的氨基及其可药用盐。所述衍生物及其药学上可接受的盐可用作抗抑郁药。

97. 发明授权

US5314920A Ethynyl-alanine aryl/alkylsulfonyl-terminated amino-diol compounds for treatment of hypertension 失效
标题翻译：用于治疗高血压的乙炔基 - 丙氨酸芳基/烷基磺酰基封端的氨基二醇化合物
公开(公告)号：US5314920A
公开(公告)日：1994-05-24
申请号：US916447
申请日：1992-07-20
申请人： Barbara B. Chen , Gunnar J. Hanson , John S. Baran
发明人： Barbara B. Chen , Gunnar J. Hanson , John S. Baran
IPC分类号： C07C317/44 , A61K31/16
CPC分类号： C07C317/44 , C07C2101/02 , C07C2101/14
摘要： Compounds characterized generally as ethynyl alanine aryl/alkylsulfonyl-terminated amino diol derivatives are useful as renin inhibitors for the treatment of hypertension. Compounds of particular interest are those of the formula ##STR1## wherein R.sup.1 is selected from isopropyl, isobutyl, sec-butyl, tert-butyl, phenyl, fluorophenyl, chlorophenyl, benzyl, fluorobenzyl, chlorobenzyl, naphthyl, fluoronaphthyl, chloronaphthyl, fluoronaphthylmethyl and chloronaphthylmethyl; wherein R.sup.2 is selected from hydrido, methyl, ethyl and phenyl; wherein R.sup.3 is selected from hydrido, cyclohexylmethyl, benzyl, fluorobenzyl, chlorobenzyl, fluoronaphthylmethyl and chloronaphthylmethyl; wherein R.sup.5 is propargyl or a propargyl-containing moeity; wherein R.sup.7 is cyclohexylmethyl; and wherein R.sup.8 is selected from n-propyl, isobutyl, cyclopropyl, cyclopropylmethyl, allyl and vinyl.
摘要翻译：通常表示乙炔基丙氨酸芳基/烷基磺酰基封端的氨基二醇衍生物的化合物可用作治疗高血压的肾素抑制剂。特别感兴趣的化合物是下式的化合物，其中R 1选自异丙基，异丁基，仲丁基，叔丁基，苯基，氟苯基，氯苯基，苄基，氟苄基，氯苄基，萘基，氟萘基，氯萘基，氟萘基甲基和氯萘基甲基 ; 其中R2选自氢，甲基，乙基和苯基; 其中R 3选自氢，环己基甲基，苄基，氟苄基，氯苄基，氟萘基甲基和氯萘基甲基; 其中R5是炔丙基或含炔丙基的摩尔; 其中R 7为环己基甲基; 并且其中R8选自正丙基，异丁基，环丙基，环丙基甲基，烯丙基和乙烯基。

98. 发明授权

US5314879A Silanyl oxypropylamines endowed with antifungal activity 失效
标题翻译：具有抗真菌活性的硅烷氧基丙基胺
公开(公告)号：US5314879A
公开(公告)日：1994-05-24
申请号：US661935
申请日：1991-02-28
申请人： Giovanni Camaggi , Lucio Filippini , Marilena Gusmeroli , Carlo Garavaglia , Luigi Mirenna
发明人： Giovanni Camaggi , Lucio Filippini , Marilena Gusmeroli , Carlo Garavaglia , Luigi Mirenna
IPC分类号： A01N43/84 , A01N33/10 , A01N43/40 , A01N43/54 , A01N55/00 , A01N55/10 , A01P3/00 , C07D213/64 , C07D213/643 , C07D239/34 , C07D265/30 , C07D295/096 , C07D413/06 , C07F7/08 , C07F7/10 , C07F7/18
CPC分类号： C07D213/643 , A01N33/10 , A01N43/40 , A01N43/54 , A01N55/00 , C07D239/34 , C07D295/096 , C07F7/0812 , C07F7/1856 , C07C2101/02 , C07C2101/08
摘要： The invention relates to the manufacture and use of aryl-propyl-aminic compounds having the following formula ##STR1## that have a high antifungal activity and are useful in the agricultural field as fungicides.
摘要翻译：本发明涉及制备和使用具有高抗真菌活性并且可作为杀真菌剂在农田中使用的具有下式“IMAGE”的芳基 - 丙基 - 氨基化合物。

99. 发明授权

US5310756A Aryloxyphenylpropylamines and their calcium overload blocking compositions and methods of use 失效
标题翻译：丙烯酰氧基苯基丙胺及其钙超载阻断组合物及其使用方法
公开(公告)号：US5310756A
公开(公告)日：1994-05-10
申请号：US898060
申请日：1992-06-12
申请人： Palle Jakobsen , Jorgen Drejer
发明人： Palle Jakobsen , Jorgen Drejer
IPC分类号： A61K31/135 , A61K31/275 , A61K31/357 , A61K31/36 , A61P9/10 , A61P21/02 , A61P25/04 , A61P25/06 , A61P25/08 , C07C213/02 , C07C217/48 , C07C217/72 , C07C253/30 , C07C255/59 , C07D317/64 , C07D521/00 , C07C255/50
CPC分类号： C07C217/72 , C07C217/48 , C07C255/59 , C07D317/64 , C07C2101/02 , C07C2102/10
摘要： Novel aryloxyphenylpropylamines having the formula ##STR1## wherein X is H, cyano, halogen, halogenoalkyl, C.sub.1-6 -alkoxy, C.sub.1- -alkyl, C.sub.1-5 -alkanoyl, C.sub.3-5 -alkylene, aryloxy- or aralkoxy, andR is 3,4-methylenedioxy, aryl or heteroaryl which are optionally substituted with one or more cyano, halogeno, C.sub.1-6 -alkyl, C.sub.1-6 -alkoxy, C.sub.1-6 -alkenyl, trifluoromethyl, C.sub.3-5 -alkylene, aryloxy or aralkoxy; andR.sup.1 and R.sup.2 independently is C.sub.1-10 -alkyl, C.sub.3-7 -cycloalkyl, C.sub.2-10 -alkenyl, C.sub.3-6 -cycloalkyl-C.sub.1-5 -alkyl, optionally substituted with C.sub.1-5 -alkoxy or cyano; orR.sup.1 and R.sup.2 may together form a carbocyclic ring and a salt thereof with a pharmaceutically acceptable acid,provided however that R.sup.1 is not C.sub.3-7 -cycloalkyl, C.sub.1-10 -alkyl, or alkenyl which may be straight, branched or cyclic, unsubstituted or substituted with C.sub.1-4 -alkoxy, aryloxy or cycloalkyl or cycloalkylalkyl, when X is H and R.sup.2 is a methyl group.The novel compounds are useful in the treatment of anoxia, migraine, ischemia, epilepsy, traumatic injury and neurode-generative diseases.
摘要翻译：具有式（I）的新型芳氧基苯基丙胺其中X为H，氰基，卤素，卤代烷基，C 1-6 - 烷氧基，C 1 - 烷基，C 1-5 - 烷酰基，C 3-5 - 亚烷基，芳氧基或芳烷氧基， R 3为任选被一个或多个氰基，卤代C 1-6烷基，C 1-6 - 烷氧基，C 1-6 - 烯基，三氟甲基，C 3-5 - 亚烷基，芳氧基或芳烷氧基; 且R 1和R 2独立地为C 1-10 - 烷基，C 3-7 - 环烷基，C 2-10 - 烯基，C 3-6 - 环烷基-C 1-5 - 烷基，任选被C 1-5 - 烷氧基或氰基取代; 或者R 1和R 2可以与药学上可接受的酸一起形成碳环和其盐，条件是R 1不是C 3-7 - 环烷基，可以是直链，支链或环状的C 1-10 - 烷基或链烯基，未取代的或被C 1-4 - 烷氧基，芳氧基或环烷基或环烷基烷基取代，当X为H且R 2为甲基时。新型化合物可用于治疗缺氧，偏头痛，局部缺血，癫痫，创伤性损伤和神经发生疾病。

100. 发明授权

US5294720A 1,4-diamino-2,3-dihydroxybutanes 失效
标题翻译： 1,4-二氨基-2,3-二羟基丁烷
公开(公告)号：US5294720A
公开(公告)日：1994-03-15
申请号：US714042
申请日：1991-05-31
申请人： Prabhakar K. Jadhav , Lawrence R. McGee , Ashok Shenvi , Carl N. Hodge
发明人： Prabhakar K. Jadhav , Lawrence R. McGee , Ashok Shenvi , Carl N. Hodge
IPC分类号： A61K31/335 , A61K31/357 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4427 , A61K31/496 , A61K31/505 , A61K38/00 , A61P31/12 , C07C215/28 , C07C217/10 , C07C225/06 , C07C225/10 , C07C233/40 , C07C233/78 , C07C235/10 , C07C235/34 , C07C235/74 , C07C235/78 , C07C237/08 , C07C237/22 , C07C243/18 , C07C243/32 , C07C251/16 , C07C257/02 , C07C257/06 , C07C257/14 , C07C271/16 , C07C271/20 , C07C271/22 , C07C271/34 , C07C275/16 , C07C275/24 , C07C311/01 , C07C311/50 , C07C317/16 , C07C323/24 , C07D207/08 , C07D211/60 , C07D213/56 , C07D213/81 , C07D215/48 , C07D235/26 , C07D239/54 , C07D257/02 , C07D277/06 , C07D295/088 , C07D295/215 , C07D317/18 , C07D317/20 , C07D317/28 , C07D333/24 , C07D401/12 , C07D407/14 , C07D495/04 , C07K1/113 , C07K5/02 , C07K5/06 , C07K5/062 , C07K5/065 , C07K5/072 , C07K5/078 , C07K7/02 , C07D213/40
CPC分类号： C07D207/08 , C07C215/28 , C07C217/10 , C07C225/06 , C07C225/10 , C07C233/40 , C07C233/78 , C07C235/10 , C07C235/34 , C07C235/74 , C07C235/78 , C07C237/22 , C07C243/18 , C07C243/32 , C07C251/16 , C07C257/02 , C07C257/06 , C07C257/14 , C07C271/16 , C07C271/20 , C07C271/22 , C07C271/34 , C07D213/56 , C07D215/48 , C07D239/54 , C07D277/06 , C07D295/088 , C07D295/215 , C07D317/20 , C07D317/28 , C07D333/24 , C07D407/14 , C07D495/04 , C07K5/021 , C07K5/06026 , C07K5/06052 , C07K5/06078 , C07K5/06104 , C07K5/06139 , C07K7/02 , A61K38/00 , C07C2101/02 , C07C2101/04 , C07C2101/08 , C07C2101/14 , C07C2102/28 , C07C2103/18 , C07C2103/74
摘要： There are provided novel 1,4 Diamine 2,3 Dihydroxybutanes useful as antiviral agents, pharmaceutical compositions containing them and processes for preparing such compounds.
摘要翻译：提供了可用作抗病毒剂的新型1,4二胺2,3-二羟基丁烷，含有它们的药物组合物和制备这些化合物的方法。

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