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    • 94. 发明申请
    • Method for Producing Optically Active Alpha-Ionone
    • 生产光学活性α-紫罗兰酮的方法
    • US20090216039A1
    • 2009-08-27
    • US11991966
    • 2006-09-13
    • Tetsuya YamamotoKenji YagiKenya Ishida
    • Tetsuya YamamotoKenji YagiKenya Ishida
    • C12P7/26C07C69/75C07C45/42
    • C12P7/26A23L2/56A23L27/204A61K8/37A61Q11/00A61Q13/00C07B53/00C07B2200/07C07C403/08C07C403/12C07C403/14C07C2601/16C12G3/06C12P41/004
    • Provided that a method for inexpensively producing optically active α-ionone with a high yield and a high asymmetric yield and with good workability in a short process, and a perfume composition comprising the optically active α-ionone obtained by the aforementioned method. A method for producing optically active α-ionone, comprising allowing α-ionone as a mixture of optical isomers to react with an esterification agent, and hydrolyzing the obtained α-ionone enol ester; a method for producing optically active α-ionone comprising subjecting α-ionone as a mixture of optical isomers to an asymmetric reduction, allowing the obtained optically active α-ionol to react with an esterification agent to give an optically active α-ionol ester, hydrolyzing the obtained optically active α-ionol ester after purification as necessary, and then oxidizing the obtained optically active α-ionol; and a perfume composition comprising thus obtained optically active α-ionone.
    • 本发明提供了一种低成本地生产光学活性α-紫罗兰酮的方法,其具有高产率和高不对称产率,并且在短时间内具有良好的可加工性,以及包含通过上述方法获得的光学活性α-紫罗兰酮的香料组合物。 一种光学活性α-紫罗兰酮的制造方法,其特征在于,使作为光学异构体的混合物的α-紫罗兰酮与酯化剂反应,水解得到的α-紫罗兰酮烯醇酯; 制备光学活性α-紫罗兰酮的方法,包括将α-紫罗烯酮作为光学异构体的混合物进行不对称还原,使得到的光学活性α-离子酚与酯化反应得到光学活性α-离子醇酯,水解 根据需要纯化后得到的光学活性α-离子醇酯,然后氧化得到的光学活性α-离子醇; 和包含由此获得的光学活性α-紫罗兰酮的香料组合物。
    • 95. 发明申请
    • Condensation Reaction by Metal Catalyst
    • 金属催化剂的缩合反应
    • US20090198070A1
    • 2009-08-06
    • US12085988
    • 2006-12-04
    • Kazushi MashimaTakashi OhshimaTakanori IwasakiHironori MaedaKenya Ishida
    • Kazushi MashimaTakashi OhshimaTakanori IwasakiHironori MaedaKenya Ishida
    • C07F15/00C07D263/08C07D263/52
    • C07D263/12B01J31/2226B01J2531/26C07C53/18C07C231/02C07C253/30C07D263/10C07D263/14C07D263/52C07D413/06C07F3/003C07F7/1892C07F9/5022C07K1/088C07K1/10
    • The invention relates to a method for producing an azoline compound represented by the general formula (3): wherein R1 represents an optionally substituted hydrocarbon group, an optionally substituted alkoxy group, an optionally substituted alkoxycarbonyl group, a halogen atom, a substituted amino group, a substituted carbamoyl group or an optionally substituted heterocyclic group; R3, R4, R5 and R6 may be the same or different and each represents a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted alkoxy group, an optionally substituted alkoxycarbonyl group, a halogen atom, a substituted amino group, a substituted carbamoyl group or an optionally substituted heterocyclic group; two arbitrary groups selected from R3, R4, R5 and R6 may bond to each other to form a ring; and Z1 represents an oxygen atom, a sulfur atom or a selenium atom; comprising reacting a carboxylic acid or a carboxylic acid derivative represented by the general formula (1): R1CO2R2  (1) wherein R1 is as defined above; R2 represents a hydrogen atom, an optionally substituted alkyl group or an optionally substituted aryl group; and R1 and R2 may bond to each other to form a ring; with an aminochalcogenide represented by the general formula (2): wherein R3, R4, R5, R6 and Z1 are as defined above; in the presence of a compound containing a group 12 metal element in the periodic table.
    • 本发明涉及一种制备由通式(3)表示的唑啉化合物的方法:其中R1表示任选取代的烃基,任选取代的烷氧基,任选取代的烷氧基羰基,卤素原子,取代的氨基, 取代的氨基甲酰基或任选取代的杂环基; R3,R4,R5和R6可以相同或不同,各自表示氢原子,任选取代的烃基,任选取代的烷氧基,任选取代的烷氧基羰基,卤素原子,取代的氨基,取代的氨基甲酰基 基团或任选取代的杂环基团; 选自R3,R4,R5和R6中的两个任意基团可以彼此键合形成环; Z1表示氧原子,硫原子或硒原子; 包括使由通式(1)表示的羧酸或羧酸衍生物反应:<?in-line-formula description =“In-line formula”end =“lead”?> R1CO2R2(1)<? -formulae description =“In-line Formulas”end =“tail”?>其中R1如上定义; R2表示氢原子,任选取代的烷基或任选取代的芳基; 并且R 1和R 2可以彼此键合形成环; 与通式(2)表示的氨基硫族化物:其中R3,R4,R5,R6和Z1如上定义; 在含有元素周期表中第12族金属元素的化合物存在下进行。
    • 97. 发明授权
    • Spray dried powdered detergents with perfume-containing capsules
    • 喷雾干燥的粉末洗涤剂含香料胶囊
    • US07538079B2
    • 2009-05-26
    • US11525048
    • 2006-09-22
    • Jonathan WarrStuart FraserEmmanuel Aussant
    • Jonathan WarrStuart FraserEmmanuel Aussant
    • C11D17/06
    • C11D3/505C11D3/046C11D3/3726C11D11/02
    • The present invention relates to a process for the manufacture of a spray dried powder comprising: (a) forming a warm, stirred aqueous slurry comprising: inorganic salts, at least one binding agent and 0.001 to 20% by weight of capsules based on the weight of spray dried powder, said capsules containing benefit agents including at least perfume, and (b) spray drying the resultant slurry to form a spray dried powder, said capsules being such that: 1) more than 40% of the benefit agents remain encapsulated 60 minutes after dispersion thereof at 70° C. in the slurry as defined in the “slurry survival test” in a sealed vessel without agitation; and 2) more than 30% of the benefit agents added for 15 minutes to an ambient slurry as defined in the “spray dry test” survive spray drying through a laboratory scale spray drier.
    • 本发明涉及一种用于制造喷雾干燥粉末的方法,包括:(a)形成温热的搅拌的含水浆料,其包含:无机盐,至少一种粘合剂和基于重量的胶囊重量为0.001至20% 所述胶囊含有至少包含香料的有益剂,和(b)喷雾干燥得到的浆料以形成喷雾干燥的粉末,所述胶囊使得:1)超过40%的有益剂保持包封60 分散在70℃下在无搅拌的密封容器中的“浆料存活试验”中定义的浆料中; 和2)如“喷雾干燥试验”中所定义的,超过30%的有益剂加入到环境浆料中15分钟,通过实验室规模的喷雾干燥器喷雾干燥。
    • 99. 发明申请
    • Spray drying
    • 喷雾干燥
    • US20070149423A1
    • 2007-06-28
    • US11525048
    • 2006-09-22
    • Jonathan WarrStuart FraserEmmanuel Aussant
    • Jonathan WarrStuart FraserEmmanuel Aussant
    • C11D3/50
    • C11D3/505C11D3/046C11D3/3726C11D11/02
    • The present invention relates to a process for the manufacture of a spray dried powder comprising: (a) forming a warm, stirred aqueous slurry comprising: inorganic salts, at least one binding agent and 0.001 to 20% by weight of capsules based on the weight of spray dried powder, said capsules containing benefit agents including at least perfume, and (b) spray drying the resultant slurry to form a spray dried powder, said capsules being such that: 1) more than 40% of the benefit agents remain encapsulated 60 minutes after dispersion thereof at 70° C. in the slurry as defined in the “slurry survival test” in a sealed vessel without agitation; and 2) more than 30% of the benefit agents added for 15 minutes to an ambient slurry as defined in the “spray dry test” survive spray drying through a laboratory scale spray drier.
    • 本发明涉及一种用于制造喷雾干燥粉末的方法,包括:(a)形成温热的搅拌的含水浆料,其包含:无机盐,至少一种粘合剂和基于重量的胶囊重量为0.001至20% 所述胶囊含有至少包含香料的有益剂,和(b)喷雾干燥得到的浆料以形成喷雾干燥的粉末,所述胶囊使得:1)超过40%的有益剂保持包封60 分散在70℃下在无搅拌的密封容器中的“浆料存活试验”中定义的浆料中; 和2)如“喷雾干燥试验”中所定义的,超过30%的有益剂加入到环境浆料中15分钟,通过实验室规模的喷雾干燥器喷雾干燥。
    • 100. 发明申请
    • Substituted optically active disphosphine compound
    • 取代的光学活性分膦化合物
    • US20070073065A1
    • 2007-03-29
    • US11526252
    • 2006-09-22
    • Takahiro FujiwaraTohru Yokozawa
    • Takahiro FujiwaraTohru Yokozawa
    • C07F9/655
    • C07F9/65517
    • Provided is a method for producing an optically active compound, in more detail, for producing an optically active compound by asymmetric hydrogenation in a high yield and asymmetric yield. The present invention also provides a catalyst for asymmetric synthesis for the above production method, especially a catalyst for asymmetric hydrogenation, containing a transition metal complex. Further, the present invention provides a new diphosphine compound useful as a ligand of the above transition metal complex and a new transition metal complex containing the above diphosphine compound. The present invention relates to a diphosphine compound represented by the following formula (1): a transition metal complex using the compound, a catalyst for asymmetric synthesis comprising the above transition metal complex and a method for producing an optically active compound using the above catalyst for asymmetric synthesis.
    • 本发明提供了一种光学活性化合物的制造方法,更详细地说,通过不对称氢化以高收率和不对称的收率制造光学活性化合物。 本发明还提供了用于上述制备方法的不对称合成催化剂,特别是含有过渡金属络合物的不对称氢化催化剂。 此外,本发明提供了可用作上述过渡金属配合物的配体的新的二膦化合物和含有上述二膦化合物的新的过渡金属络合物。 本发明涉及由下式(1)表示的二膦化合物:使用该化合物的过渡金属络合物,包含上述过渡金属配合物的不对称合成催化剂和使用上述催化剂制备光学活性化合物的方法 不对称合成。