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91. 发明申请

US20140273708A1 Water and Bubble Toy 审中-公开
标题翻译：水和泡泡玩具
公开(公告)号：US20140273708A1
公开(公告)日：2014-09-18
申请号：US13835733
申请日：2013-03-15
申请人： Bo Chen
发明人： Bo Chen
IPC分类号： A63H33/28
CPC分类号： A63H33/28
摘要： A water and bubble toy includes a water projecting assembly and a bubble generating assembly. Water is stored in a water reservoir located in a rear handle of the toy while bubble solution is stored in a detachable reservoir. The water generating assembly is operated by a lever located toward an upper end of the toy. When the lever is pulled, the lever activates a first pump that expels water from the toy. The bubble generating assembly is operated by a finger trigger that activates an electric motor, which powers a second pump and a fan. The second pump pumps bubble solution to a ring and the bubble solution coats the ring. The fan blows air through the ring and helps generate and propel bubbles from the ring.
摘要翻译：水和泡泡玩具包括水投射组件和发泡组件。将水储存在位于玩具的后把手中的储水器中，同时将气泡溶液储存在可拆卸的储存器中。发水组件由位于玩具上端的杆操作。拉杆时，杠杆启动第一个泵，从玩具中排出水。气泡生成组件由手指触发器操作，该手指触发器激活电动机，该电动机为第二泵和风扇供电。第二个泵将气泡溶液泵送到环上，气泡溶液涂覆环。风扇吹过空气通过环，有助于产生并推动环中的气泡。

92. 发明授权

US08748669B2 Process for producing aldehydes or ketones by oxidizing alcohols with oxygen 有权
标题翻译：通过用氧氧化醇生产醛或酮的方法
公开(公告)号：US08748669B2
公开(公告)日：2014-06-10
申请号：US13497960
申请日：2010-07-30
申请人： Shengming Ma , Jinxian Liu , Jinqiang Kuang , Yu Liu , Yuli Wang , Qiong Yu , Weiming Yuan , Suhua Li , Bo Chen , Jiajia Cheng , Baoqiang Wan , Juntao Ye , Shichao Yu
发明人： Shengming Ma , Jinxian Liu , Jinqiang Kuang , Yu Liu , Yuli Wang , Qiong Yu , Weiming Yuan , Suhua Li , Bo Chen , Jiajia Cheng , Baoqiang Wan , Juntao Ye , Shichao Yu
IPC分类号： C07C45/38 , C07C45/39
CPC分类号： C07C45/38 , B01J31/006 , B01J31/28 , B01J2231/763 , B01J2531/842 , C07C45/39 , C07C201/12 , C07C2601/14 , C07C2601/16 , C07F7/1804 , C07C47/232 , C07C47/21 , C07C49/203 , C07C49/217 , C07C49/235 , C07C49/207 , C07C49/794 , C07C49/807 , C07C49/80 , C07C49/84 , C07C47/222 , C07C47/277 , C07C49/683 , C07C47/55 , C07C47/575 , C07C49/78 , C07C47/02 , C07C49/04 , C07C49/403 , C07C205/44
摘要： Provided is a process for producing aldehydes or ketones by oxidizing alcohols with oxygen, which comprises oxidizing alcohols to aldehydes or ketones in an organic solvent at room temperature with oxygen or air as an oxidant, wherein ferric nitrate (Fe(NO3)3.9H2O), 2,2,6,6-tetramethylpiperidine N-oxyl (TEMPO) and an inorganic chloride are used as catalysts, the reaction time is 1-24 hours, and the molar ratio of said alcohols, 2,2,6,6-tetramethylpiperidine N-oxyl and the inorganic chloride is 100:1˜10:1˜10:1˜10. The present process has the advantages of high yield, mild reaction conditions, simple operation, convenient separation and purification, recoverable solvents, substrates used therefor being various and no pollution, and therefore it is adaptable to industrialization.
摘要翻译：本发明提供一种通过用氧氧化醇来生产醛或酮的方法，该方法包括在室温下用氧气或空气作为氧化剂将醇氧化成有机溶剂中的醛或酮，其中硝酸铁（Fe（NO 3）3·4H 2 O）使用2,2,6,6-四甲基哌啶N-氧基（TEMPO）和无机氯化物作为催化剂，反应时间为1-24小时，所述醇，2,2,6,6-四甲基哌啶的摩尔比 N-氧基和无机氯化物为100:1〜10:1〜10:1〜10。本发明方法具有产量高，反应条件温和，操作简便，分离纯化方便，可回收溶剂，各种基材不污染，适用于工业化。

93. 发明申请

US20140073890A1 SYSTEMS AND METHODS FOR DETERMINING FLUID RESPONSIVENESS 审中-公开
标题翻译：用于确定流体响应的系统和方法
公开(公告)号：US20140073890A1
公开(公告)日：2014-03-13
申请号：US13611269
申请日：2012-09-12
申请人： Mark Su , Bo Chen
发明人： Mark Su , Bo Chen
IPC分类号： A61B5/0205 , A61B5/1455
CPC分类号： A61B5/0205 , A61B5/02116 , A61B5/0215 , A61B5/082 , A61B5/087 , A61B5/1455 , A61B5/4833 , A61B5/4839 , A61B5/7235
摘要： A system is provided including a respiratory detection module, a circulatory detection module, and an analysis module. The respiratory detection module is configured to detect respiratory information representative of respiration of a patient. The circulatory detection module configured to detect circulatory information representative of circulation of the patient. The analysis module is configured to obtain a respiratory waveform based at least in part on the respiratory information, obtain a circulatory waveform based at least in part on the circulatory information, combine the respiratory waveform and the circulatory waveform to provide a mixed waveform, and isolate a portion of the mixed waveform to identify a respiratory responsiveness waveform representative of an effect of the respiration of the patient on the mixed waveform.
摘要翻译：提供了一种包括呼吸检测模块，循环检测模块和分析模块的系统。呼吸检测模块被配置为检测代表患者呼吸的呼吸信息。循环检测模块被配置为检测表示患者的循环的循环信息。分析模块被配置为至少部分地基于呼吸信息获得呼吸波形，至少部分地基于循环信息获得循环波形，组合呼吸波形和循环波形以提供混合波形，并隔离混合波形的一部分，以识别代表患者对混合波形的呼吸的影响的呼吸反应性波形。

94. 发明授权

US08649838B2 Wavelength switching for pulse oximetry 有权
标题翻译：脉搏血氧仪的波长切换
公开(公告)号：US08649838B2
公开(公告)日：2014-02-11
申请号：US12888226
申请日：2010-09-22
申请人： Bo Chen , Edward M. McKenna , Youzhi Li , Daniel Lisogurski
发明人： Bo Chen , Edward M. McKenna , Youzhi Li , Daniel Lisogurski
IPC分类号： A61B5/1455
CPC分类号： A61B5/14552 , A61B5/0205 , A61B5/02427 , A61B5/14551 , A61B2560/02
摘要： The present disclosure describes techniques that may provide more accurate estimates of arterial oxygen saturation using pulse oximetry by switching between a wavelength spectrum of at least a first and a second light source so that the arterial oxygen saturation estimates at low (e.g., in the range below 75%), medium (e.g., greater than or equal to 75% and less than or equal to 84%), and high (e.g., greater than 84% range) arterial oxygen saturation values are more accurately calculated. In one embodiment, light emitted from a near 660 nm and a near 900 nm emitter pair may be used when the arterial oxygen saturation range is high. In another embodiment, light emitted from a near 730 nm and a near 900 nm emitter pair may be used when the arterial oxygen saturation range is low. In yet another embodiment, light emitted from both a near 660 nm-900 nm emitter pair and light emitted from a near 730 nm-900 nm emitter pair may be used when the arterial oxygen saturation range is in the middle range. Priming techniques may also be used to reduce or eliminate start up delays of certain oximetry system components.
摘要翻译：本公开描述了可以通过在至少第一和第二光源的波长光谱之间切换使得使用脉搏血氧饱和度更准确地估计动脉血氧饱和度的技术，使得动脉血氧饱和度估计为低（例如，在下面的范围内 75％），中等（例如，大于或等于75％且小于或等于84％）和高（例如，大于84％的范围）动脉血氧饱和度值被更准确地计算。在一个实施例中，当动脉血氧饱和度范围高时，可以使用从近660nm和近900nm发射体对发射的光。在另一个实施例中，当动脉血氧饱和度范围低时，可以使用从近730nm和近900nm发射体对发射的光。在另一个实施例中，当动脉血氧饱和度范围在中间范围时，可以使用从近660nm-900nm发射体对发射的光和从近730nm-900nm发射体对发射的光。引发技术也可用于减少或消除某些血氧饱和度系统组件的启动延迟。

95. 发明申请

US20130286379A1 COMBINED LIGHT SOURCE PHOTOACOUSTIC SYSTEM 有权
标题翻译：组合光源光电系统
公开(公告)号：US20130286379A1
公开(公告)日：2013-10-31
申请号：US13459933
申请日：2012-04-30
申请人： Youzhi Li , Bo Chen
发明人： Youzhi Li , Bo Chen
IPC分类号： G01N21/00 , G01N33/49
CPC分类号： A61B5/0095 , G01N21/1702
摘要： A physiological monitoring system may use photoacoustic sensing to determine one or more physiological parameters of a subject. The photoacoustic system may use two light sources (e.g., a high power pulsed laser diode and a continuous wave laser diode) to generate acoustic pressure signals in a subject. One or more light sources (e.g., the high powered pulsed laser diode) may provide a high signal-to-noise ratio. The high signal-to-noise ratio signals may provide high sensitivity for physiological measurements (e.g., cardiac output and temperature measurements). The photoacoustic system may use high powered light sources in combination with other light sources to improve physiological measurements.
摘要翻译：生理监测系统可以使用光声感测来确定受试者的一个或多个生理参数。光声系统可以使用两个光源（例如，高功率脉冲激光二极管和连续波激光二极管）来在对象中产生声压信号。一个或多个光源（例如，高功率脉冲激光二极管）可以提供高的信噪比。高信噪比信号可以为生理测量（例如，心输出量和温度测量）提供高灵敏度。光声系统可以使用与其他光源组合的高功率光源来改善生理测量。

96. 发明申请

US20130230525A1 PROTEIN COMPLEXES FOR ANTIGEN BINDING AND METHODS OF USE 有权
标题翻译：用于抗原结合的蛋白复合物和使用方法
公开(公告)号：US20130230525A1
公开(公告)日：2013-09-05
申请号：US13883282
申请日：2011-11-09
申请人： Zijuan Li , Chun Wu , Jun Bao , Bo Chen
发明人： Zijuan Li , Chun Wu , Jun Bao , Bo Chen
IPC分类号： C07K16/46 , G01N33/68
CPC分类号： C07K16/468 , A61K38/00 , A61K2039/505 , C07K16/00 , C07K16/248 , C07K16/2803 , C07K16/2809 , C07K16/2878 , C07K16/30 , C07K16/40 , C07K16/46 , C07K2317/30 , C07K2317/31 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/66 , C07K2317/73 , G01N33/6854
摘要： Provided herein in certain embodiments are polypeptide complexes capable of binding to an antigen. Pharmaceutical compositions, method of using the polypeptide complexes are also provided.
摘要翻译：本文在某些实施方案中提供能够结合抗原的多肽复合物。还提供了药物组合物，使用多肽复合物的方法。

97. 发明申请

US20130190589A1 MULTIPLE PEAK ANALYSIS IN A PHOTOACOUSTIC SYSTEM 审中-公开
标题翻译：光电系统中的多峰分析
公开(公告)号：US20130190589A1
公开(公告)日：2013-07-25
申请号：US13357839
申请日：2012-01-25
申请人： Bo Chen , Youzhi Li
发明人： Bo Chen , Youzhi Li
IPC分类号： A61B5/05
CPC分类号： A61B5/0095 , A61B5/145
摘要： A physiological monitoring system may use photoacoustic sensing to determine one or more physiological parameters of a subject. A photoacoustic signal generated in response to a photonic signal may include multiple peaks as a result of multiple blood vessels and other structures below the surface of the skin of a subject. A photoacoustic system may identify a first and second peak in the photoacoustic signal and determine values from the peaks indicative of physiological parameters. Physiological parameters, such as venous oxygen saturation and arterial oxygen saturation, may be determined based on the values.
摘要翻译：生理监测系统可以使用光声感测来确定受试者的一个或多个生理参数。响应于光子信号产生的光声信号可以包括作为受试者皮肤表面下方的多个血管和其它结构的结果的多个峰。光声系统可以识别光声信号中的第一和第二峰，并从表示生理参数的峰值确定值。可以基于这些值来确定生理参数，例如静脉血氧饱和度和动脉血氧饱和度。

98. 发明申请

US20130109941A1 METHODS AND SYSTEMS FOR PHOTOACOUSTIC SIGNAL PROCESSING 审中-公开
标题翻译：光电信号处理方法与系统
公开(公告)号：US20130109941A1
公开(公告)日：2013-05-02
申请号：US13284580
申请日：2011-10-28
申请人： Youzhi Li , Bo Chen
发明人： Youzhi Li , Bo Chen
IPC分类号： A61B5/145 , A61B6/00
CPC分类号： G01N21/4738 , A61B5/0095 , A61B5/021 , A61B5/02416 , A61B5/0255 , A61B5/14551 , A61B2562/0233 , G01N21/1702 , G01N21/49
摘要： A physiological monitoring system may perform an optical measurement of a subject to assist a photoacoustic analysis of the subject. For example, an oblique-incidence diffuse reflectance measurement, photon density wave measurement, or other optical measurement may be used to determine one or more optical properties of a subject. Accordingly, the one or more optical properties may be used to determine an optical fluence at a region of the subject. In some arrangements, a physiological monitoring system may include an oximeter, and may use a calculated blood oxygen saturation value to assist a photoacoustic analysis. Photoacoustic analysis may include determining one or more physiological parameters based on a detected acoustic pressure response of a subject to a photonic signal via the photoacoustic effect.
摘要翻译：生理监测系统可以执行对象的光学测量以辅助对象的光声分析。例如，可以使用倾斜入射漫反射测量，光子密度波测量或其它光学测量来确定被摄体的一个或多个光学特性。因此，可以使用一个或多个光学特性来确定受试者的区域处的光能。在一些布置中，生理监测系统可以包括血氧计，并且可以使用计算的血氧饱和度值来辅助光声分析。光声分析可以包括基于通过光声效应对受试者对光子信号的检测的声压响应来确定一个或多个生理参数。

99. 发明申请

US20120203087A1 SYSTEMS AND METHODS FOR MONITORING DEPTH OF CONSCIOUSNESS 有权
标题翻译：监测深度深度的系统和方法
公开(公告)号：US20120203087A1
公开(公告)日：2012-08-09
申请号：US13364766
申请日：2012-02-02
申请人： Edward M. McKenna , Bo Chen , Youzhi Li , Paul Stanley Addison , James N. Watson
发明人： Edward M. McKenna , Bo Chen , Youzhi Li , Paul Stanley Addison , James N. Watson
IPC分类号： A61B5/00 , A61B6/00 , A61B5/04 , A61B5/1455 , A61B5/021
CPC分类号： A61B5/14551 , A61B5/04001 , A61B5/0476 , A61B5/40 , A61B5/4821 , A61B5/7239 , A61B5/7264 , G06F19/00 , G16H50/20 , G16H50/30
摘要： During patient monitoring, a depth of consciousness (DOC) measure, such as a bispectral index, may be used in conjunction with additional information obtained from an awareness metric derived from one or more physiological signals, such as a photoplethysmograph signal. In an embodiment, a DOC measure may be combined with information from an awareness metric to produce a combined DOC measure. In an embodiment, information from an awareness metric derived from one or more physiological signals may be used to provide an indication of confidence in a DOC measure. In an embodiment, a DOC measure may be used to provide an indication of confidence in a depth of consciousness assessment based on an awareness metric. In an embodiment, one or the other of a DOC measure and an awareness metric may be used to provide an indication of a patient's depth of consciousness (e.g., by one “overriding” the other).
摘要翻译：在患者监视期间，可以结合从源自一个或多个生理信号（诸如光电体积描记信号）的意识度量获得的附加信息结合使用意识深度（DOC）测量，例如双谱指数。在一个实施例中，DOC测量可以与来自感知度量的信息组合以产生组合的DOC测量。在一个实施例中，可以使用来自一个或多个生理信号的意识度量的信息来提供在DOC测量中的置信度。在一个实施例中，DOC测量可以用于基于意识度量提供意识深度评估深度的置信度。在一个实施例中，可以使用DOC测量和意识度量中的一个或另一个来提供患者的意识深度的指示（例如，通过一个“覆盖”另一个）。

100. 发明授权

US08127072B2 Data storage device and method for accessing flash memory 有权
标题翻译：用于访问闪存的数据存储设备和方法
公开(公告)号：US08127072B2
公开(公告)日：2012-02-28
申请号：US12497665
申请日：2009-07-04
申请人： Bo Chen
发明人： Bo Chen
IPC分类号： G06F12/10
CPC分类号： G06F12/0246 , G06F2212/1044 , G06F2212/401 , G06F2212/7202
摘要： The invention provides a method for accessing a flash memory. In one embodiment, the flash memory comprises a plurality of memory units, each of the memory units has a physical address, and an address link table records a mapping relationship between a plurality of logical addresses and a plurality of physical addresses. First, first data to be written to a first logical address is received from a host. Whether the first data is predetermined data is the determined. Whether the first logical address is mapped to a null physical address is then determined according to the address link table. When the first data is the predetermined data and the first logical address is not mapped to the null physical address according to the address link table, the address link table is modified to map the first logical address to the null physical address.
摘要翻译：本发明提供了一种访问闪存的方法。在一个实施例中，闪速存储器包括多个存储器单元，每个存储器单元都具有物理地址，并且地址链接表记录多个逻辑地址与多个物理地址之间的映射关系。首先，从主机接收到要写入第一逻辑地址的第一数据。确定第一数据是否为预定数据。然后根据地址链接表确定第一逻辑地址是否映射到空物理地址。当第一数据是预定数据，并且第一逻辑地址根据地址链接表未映射到空物理地址时，地址链接表被修改以将第一逻辑地址映射到空物理地址。

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