专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09354241B2 Moesin fragments associated with aplastic anemia 有权
标题翻译：与再生障碍性贫血相关的Moesin片段
公开(公告)号：US09354241B2
公开(公告)日：2016-05-31
申请号：US13878235
申请日：2011-10-08
申请人： Yue Zhang , Jun Bao , Hua Mao , Fei Xiang , Hongbin Sun , Jie Qian , Yongjun Han , Weina Situ
发明人： Yue Zhang , Jun Bao , Hua Mao , Fei Xiang , Hongbin Sun , Jie Qian , Yongjun Han , Weina Situ
IPC分类号： G01N33/68 , A61K38/19 , C07K14/52 , G01N33/564
CPC分类号： G01N33/6893 , A61K38/19 , C07K14/52 , G01N33/564 , G01N2800/22
摘要： The present application provides compositions and methods useful for detecting and monitoring acquired aplastic anemia.
摘要翻译：本申请提供了用于检测和监测获得性再生障碍性贫血的组合物和方法。

2. 发明授权

US09347950B2 Moesin fragments associated with immune thrombocytopenia 有权
标题翻译：与免疫血小板减少相关的Moesin片段
公开(公告)号：US09347950B2
公开(公告)日：2016-05-24
申请号：US13878237
申请日：2011-10-08
申请人： Yue Zhang , Jun Bao
发明人： Yue Zhang , Jun Bao
IPC分类号： G01N33/68 , C07K14/52 , G01N33/564
CPC分类号： G01N33/6854 , C07K14/52 , C07K2319/02 , C07K2319/50 , G01N33/564 , G01N2800/222 , G01N2800/52
摘要： The present application provides compositions and methods useful for detecting and monitoring immune thrombocytopenia.
摘要翻译：本申请提供了用于检测和监测免疫血小板减少症的组合物和方法。

3. 发明授权

US09148710B2 Raman amplifier system and method with integrated optical time domain reflectometer 有权
标题翻译：具有集成光时域反射计的拉曼放大器系统和方法
公开(公告)号：US09148710B2
公开(公告)日：2015-09-29
申请号：US13622481
申请日：2012-09-19
申请人： Jean-Luc Archambault , Jun Bao , Balakrishnan Sridhar
发明人： Jean-Luc Archambault , Jun Bao , Balakrishnan Sridhar
IPC分类号： H04B10/291 , H04Q9/00 , H04B10/071 , G01M11/00 , H01S3/094 , H01S3/30
CPC分类号： H04B10/0797 , G01M11/3109 , G01M11/3136 , G01M11/319 , H01S3/094042 , H01S3/094046 , H01S3/1312 , H01S3/302 , H04B10/071 , H04B10/0731 , H04B10/2916 , H04J14/0227 , H04Q9/00
摘要： Raman amplifier systems and methods with an integrated Optical Time Domain Reflectometer (OTDR) for integrated testing functionality include an amplifier system, an OTDR and telemetry subsystem, and a method of operation. The OTDR and telemetry subsystem is configured to operate in an OTDR mode when coupled to a line in port and to operate in a telemetry mode when coupled to a line out port. The OTDR and telemetry subsystem enables on-demand fiber testing while also operating as a telemetry channel that is both a redundant optical service channel (OSC) and provides a mechanism to monitor Raman gain over time. The OTDR and telemetry subsystem minimizes cost and space by sharing major optical and electrical components between the integrated OTDR and other functions on the Raman amplifier.
摘要翻译：具有用于集成测试功能的集成光时域反射计（OTDR）的拉曼放大器系统和方法包括放大器系统，OTDR和遥测子系统以及操作方法。 OTDR和遥测子系统配置为在耦合到端口线路时以OTDR模式运行，并且在耦合到线路输出端口时以遥测模式运行。 OTDR和遥测子系统实现了按需光纤测试，同时也作为冗余光学服务通道（OSC）的遥测通道运行，并提供了一种随时间监测拉曼增益的机制。 OTDR和遥测系统通过在集成OTDR和拉曼放大器上的其他功能之间共享主要的光学和电气部件，最大限度地降低成本和空间。

4. 发明申请

US20140077971A1 RAMAN AMPLIFIER SYSTEM AND METHOD WITH INTEGRATED OPTICAL TIME DOMAIN REFLECTOMETER 有权
标题翻译：拉曼放大器系统和方法与集成光时域反射计
公开(公告)号：US20140077971A1
公开(公告)日：2014-03-20
申请号：US13622481
申请日：2012-09-19
申请人： Jean-Luc Archambault , Jun Bao , Balakrishnan Sridhar
发明人： Jean-Luc Archambault , Jun Bao , Balakrishnan Sridhar
IPC分类号： G08C23/04
CPC分类号： H04B10/0797 , G01M11/3109 , G01M11/3136 , G01M11/319 , H01S3/094042 , H01S3/094046 , H01S3/1312 , H01S3/302 , H04B10/071 , H04B10/0731 , H04B10/2916 , H04J14/0227 , H04Q9/00
摘要： Raman amplifier systems and methods with an integrated Optical Time Domain Reflectometer (OTDR) for integrated testing functionality include an amplifier system, an OTDR and telemetry subsystem, and a method of operation. The OTDR and telemetry subsystem is configured to operate in an OTDR mode when coupled to a line in port and to operate in a telemetry mode when coupled to a line out port. The OTDR and telemetry subsystem enables on-demand fiber testing while also operating as a telemetry channel that is both a redundant optical service channel (OSC) and provides a mechanism to monitor Raman gain over time. The OTDR and telemetry subsystem minimizes cost and space by sharing major optical and electrical components between the integrated OTDR and other functions on the Raman amplifier.
摘要翻译：具有用于集成测试功能的集成光时域反射计（OTDR）的拉曼放大器系统和方法包括放大器系统，OTDR和遥测子系统以及操作方法。 OTDR和遥测子系统配置为在耦合到端口线路时以OTDR模式运行，并且在耦合到线路输出端口时以遥测模式运行。 OTDR和遥测子系统实现了按需光纤测试，同时也作为冗余光学服务通道（OSC）的遥测通道运行，并提供了一种随时间监测拉曼增益的机制。 OTDR和遥测系统通过在集成OTDR和拉曼放大器上的其他功能之间共享主要的光学和电气部件，最大限度地降低成本和空间。

5. 发明申请

US20130211051A1 FUSION PROTEIN CONTAINING VEGI, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 审中-公开
标题翻译：含有VEGI的融合蛋白和药物组合物及其用途
公开(公告)号：US20130211051A1
公开(公告)日：2013-08-15
申请号：US13878495
申请日：2010-12-27
申请人： Xiangming Sun , Ling Zhou , Jiannan Hong , Yun Wu , Jun Bao
发明人： Xiangming Sun , Ling Zhou , Jiannan Hong , Yun Wu , Jun Bao
IPC分类号： C07K14/435 , C07K16/18
CPC分类号： C07K14/435 , A61K38/00 , C07K14/70575 , C07K16/18 , C07K2319/00 , C07K2319/30
摘要： Provided is an anti-angiogenic fusion protein, which comprises a vascular endothelial cell growth inhibitor (VEGI) or variant thereof, and other polypeptide such as IgG Fc. The fusion protein optionally comprises a linker. The fusion protein can induce the apoptosis of endothelial cells and inhibit the growtth of endothelial cells, so as to be used for treating tumor. Also provided are a pharmaceutical composition and use of the fusion protein.
摘要翻译：提供了抗血管生成融合蛋白，其包含血管内皮细胞生长抑制剂（VEGI）或其变体，以及其它多肽如IgG Fc。融合蛋白任选地包含接头。融合蛋白可诱导内皮细胞凋亡，抑制内皮细胞生长，用于治疗肿瘤。还提供了药物组合物和融合蛋白的用途。

6. 发明申请

US20130203091A1 MOESIN FRAGMENTS ASSOCIATED WITH APLASTIC ANEMIA 有权
标题翻译：与APLASTIC ANEMIA相关的MOESIN片段
公开(公告)号：US20130203091A1
公开(公告)日：2013-08-08
申请号：US13878235
申请日：2011-10-08
申请人： Yue Zhang , Jun Bao , Hua Mao , Fei Xiang , Hongbin Sun , Jie Qian , Yongjun Han , Weina Situ
发明人： Yue Zhang , Jun Bao , Hua Mao , Fei Xiang , Hongbin Sun , Jie Qian , Yongjun Han , Weina Situ
IPC分类号： G01N33/68
CPC分类号： G01N33/6893 , A61K38/19 , C07K14/52 , G01N33/564 , G01N2800/22
摘要： The present application provides compositions and methods useful for detecting and monitoring acquired aplastic anemia.
摘要翻译：本申请提供了用于检测和监测获得性再生障碍性贫血的组合物和方法。

7. 发明申请

US20130097717A1 COMPOSITIONS AND METHODS FOR RE-PROGRAMMING CELLS WITHOUT GENETIC MODIFICATION FOR TREATMENT OF CARDIOVASCULAR DISEASES 审中-公开
标题翻译：用于重新编程细胞的组合物和方法，不进行遗传修饰以治疗心血管疾病
公开(公告)号：US20130097717A1
公开(公告)日：2013-04-18
申请号：US13806781
申请日：2011-06-23
申请人： Yong Zhu , Shili Wu , Jun Bao
发明人： Yong Zhu , Shili Wu , Jun Bao
IPC分类号： A61K38/16
CPC分类号： A61K38/16 , A61K38/00 , B82Y5/00 , C12N5/0637 , C12N5/0696 , C12N2501/60 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606 , Y10S977/773
摘要： The present inventions are directed to compositions and methods regarding the reprogramming of other cells (such as fibroblast cells) into cardiomyocytes without introducing exogenous genes to the samples. In particular, the present inventions are directed to transducible materials that are capable of transducing into the biological samples but are not genes or causing genetic modifications. The present inventions also are directed to methods of reprogramming the path of biological samples or treating diseases using the tranducible compositions thereof.
摘要翻译：本发明涉及关于将其它细胞（例如成纤维细胞）重编程成心肌细胞而不向样品中引入外源基因的组合物和方法。特别地，本发明涉及能够转导到生物样品但不是基因或引起遗传修饰的可导纳材料。本发明还涉及使用其可转导组合物重新编程生物样品的路径或治疗疾病的方法。

8. 发明申请

US20110258713A1 COMPOSITIONS AND METHODS FOR RE-PROGRAMMING CELLS WITHOUT GENETIC MODIFICATION 审中-公开
标题翻译：用于重新编程细胞的组合物和方法，无遗传修饰
公开(公告)号：US20110258713A1
公开(公告)日：2011-10-20
申请号：US13141326
申请日：2009-12-23
申请人： Yong Zhu , Shili Wu , Jun Bao
发明人： Yong Zhu , Shili Wu , Jun Bao
IPC分类号： A01K67/033 , C12N5/04 , C12N5/07 , C12N5/071 , C12N5/0783 , C12Q1/02 , C07K14/435 , A61K38/17 , A61P35/00 , A61P3/00 , A61P29/00 , A61P9/00 , A61P25/00 , A61P37/00 , A61P3/10 , A61P25/28 , A61P25/16 , A61P7/06 , A61P19/02 , A61P17/02 , A61P17/00 , A61P1/16 , A61P27/16 , A61P1/04 , A61P21/04 , A61P25/18 , A61K49/00 , A61M37/00 , C12N1/00 , B82Y5/00
CPC分类号： C12N5/0696 , A61K2035/122 , C12N5/0637 , C12N5/0676 , C12N2501/60 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606
摘要： The present inventions are directed to compositions and methods regarding the reprogramming of biological samples (such as cells) without introducing exogenous genes to the samples. In particular, the present inventions are directed to transducible materials that are capable of transducing into the biological samples but are not genes or causing genetic modifications. The present inventions also are directed to methods of reprogramming the path of biological samples or treating diseases using the tranducible compositions thereof.
摘要翻译：本发明涉及关于生物样品（例如细胞）的重新编程而不向样品中引入外源基因的组合物和方法。特别地，本发明涉及能够转导到生物样品但不是基因或引起遗传修饰的可导纳材料。本发明还涉及使用其可转导组合物重新编程生物样品的路径或治疗疾病的方法。

9. 发明申请

US20110043896A1 OPTICAL MODULE MANUFACTURING AND TESTING SYSTEMS AND METHODS 有权
标题翻译：光学模块制造与测试系统及方法
公开(公告)号：US20110043896A1
公开(公告)日：2011-02-24
申请号：US12542899
申请日：2009-08-18
申请人： Jun BAO
发明人： Jun BAO
IPC分类号： H01S3/00
CPC分类号： H01S3/06704
摘要： The present disclosure relates to streamlining optical module and/or subassembly development, manufacturing, and testing through introducing a memory component within a module and/or subassembly that is utilized with a host module for system calibration and/or configuration. In an exemplary embodiment, the present invention can streamline optical amplifier (EDFA) module and/or subassembly development, manufacturing, and testing. The present invention includes an optical module/sub-assembly without control circuitry, i.e. a “dumb module”, but with a memory that is used to load relevant data from a supplier. This data is utilized to calibrate, test, and configure the optical module/sub-assembly in a host module. The host module includes control circuitry to access this memory in the optical module/sub-assembly and to calibrate, test, configure, and control the optical module/sub-assembly. Advantageously, this additional memory reduces manufacturing time without the disadvantage of adding complexity in the optical module/sub-assembly.
摘要翻译：本公开涉及通过在与主机模块一起用于系统校准和/或配置的模块和/或子组件内引入存储器组件来简化光学模块和/或子组件开发，制造和测试。在示例性实施例中，本发明可以简化光放大器（EDFA）模块和/或子组件开发，制造和测试。本发明包括没有控制电路的光学模块/子组件，即“哑模块”，但是具有用于从供应商加载相关数据的存储器。该数据用于校准，测试和配置主机模块中的光模块/子组件。主机模块包括用于访问光学模块/子组件中的该存储器并且校准，测试，配置和控制光学模块/子组件的控制电路。有利地，该附加存储器减少了制造时间，而没有增加光学模块/子组件的复杂性的缺点。

10. 发明申请

US20100183311A1 HIGH-DEGREE RECONFIGURABLE OPTICAL ADD-DROP MULTIPLEXING SYSTEMS USING BI-DIRECTIONAL WAVELENGTH SELECTIVE SWITCHES 有权
标题翻译：使用双向波长选择开关的高可重构光学放大多路复用系统
公开(公告)号：US20100183311A1
公开(公告)日：2010-07-22
申请号：US12356593
申请日：2009-01-21
申请人： Xiaohui YANG , Zhonghua ZHU , Jun BAO
发明人： Xiaohui YANG , Zhonghua ZHU , Jun BAO
IPC分类号： H04J14/02
CPC分类号： H04Q11/0005 , H04J14/0205 , H04J14/0206 , H04J14/0212 , H04J14/0213 , H04J14/0217 , H04J14/0219 , H04J14/0284 , H04Q2011/0035 , H04Q2011/0052
摘要： The present disclosure provides high-degree reconfigurable optical add-drop multiplexing (ROADM) systems using bi-directional wavelength selective switches (WSSs) and optical circulators. A single WSS is utilized on each degree of a node in a bi-directional manner, i.e. both ingress and egress share the same WSS. Advantageously, the present invention eliminates conventional splitters/combiners thereby capping intra-node insertion loss to a certain value regardless of the number of degrees. More importantly, the present invention reduces noise penalty associated with high-degree nodes while minimizing cost.
摘要翻译：本公开提供使用双向波长选择开关（WSS）和光学循环器的高度可重构的光分插复用（ROADM）系统。以双向方式在每个节点上使用单个WSS，即入口和出口共享相同的WSS。有利地，本发明消除了传统的分离器/组合器，从而将节点内插入损耗限制到一定值，而不管度数。更重要的是，本发明降低了与高度节点相关联的噪声，同时最小化了成本。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式