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    • 95. 发明授权
    • Ceramic-metal joint structure
    • 陶瓷 - 金属接头结构
    • US4723862A
    • 1988-02-09
    • US879538
    • 1986-06-24
    • Masaya ItoNoboru Ishida
    • Masaya ItoNoboru Ishida
    • B23K1/19B23K35/00C04B37/02F16B11/00
    • C04B37/026B23K35/001C04B2237/123C04B2237/124C04B2237/125C04B2237/126C04B2237/368C04B2237/406C04B2237/708C04B2237/72Y10T403/479Y10T403/74
    • A power-transmitting ceramic to metal joint structure including a first shaft consisting essentially of a sintered ceramic material, one portion of the shaft defining a first mating surface; an intermediate insert consisting essentially of a sintered ceramic material, the insert having two opposite insert mating surfaces, the insert having a thickness between the opposite insert mating surfaces in the range of from about 1.5 to about 20% of a distance defined by the cross section of the first mating surface and a flexural strength of not less than about 70% of the sintered ceramic material comprising the first shaft; a second shaft consisting essentially of metal, one portion of the second shaft defining a second mating surface; and brazing filler means affixing the first mating surface to one of the insert mating surfaces and the second mating surface to the opposite insert mating surface, the aforementioned mating surfaces being affixed in abutting relationships. Preferably, the intermediate insert has a thermal expansion coefficient in the range from about that of the first shaft to about that of the second shaft.
    • 一种动力传递陶瓷 - 金属接头结构,包括基本上由烧结陶瓷材料组成的第一轴,所述轴的一部分限定第一配合表面; 基本上由烧结陶瓷材料组成的中间插入件,所述插入件具有两个相对的插入配合表面,所述插入件在相对的插入配合表面之间的厚度在由截面限定的距离的约1.5至约20%的范围内 的第一配合表面,并且具有不小于包含第一轴的烧结陶瓷材料的约70%的弯曲强度; 基本上由金属组成的第二轴,所述第二轴的一部分限定第二配合表面; 以及钎焊装置,其将所述第一配合表面固定到所述插入配合表面和所述第二配合表面中的一个到相对的插入配合表面,所述配合表面以邻接关系固定。 优选地,中间插入件的热膨胀系数在从大约第一轴到第二轴的热膨胀系数的范围内。
    • 96. 发明授权
    • 7-Oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives, their
use and preparation
    • 7-氧代-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸衍生物,其用途和制备方法
    • US4377591A
    • 1983-03-22
    • US239139
    • 1981-02-27
    • Tetsuo HiraokaTakeo KobayashiNoboru IshidaShinichi Sugawara
    • Tetsuo HiraokaTakeo KobayashiNoboru IshidaShinichi Sugawara
    • C07D477/00A61K31/397A61K31/40A61P31/04C07D205/08C07D477/14C07F7/10C07F7/18C07F9/568C07D487/04
    • C07D477/14C07D205/08C07F7/10C07F7/186C07F9/5683Y02P20/55
    • 7-Oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives of formula (I): ##STR1## (in which:) R.sup.1 represents a hydrogen atom or an optionally substituted alkyl group;X represents an oxy group, a thio group, a sulphinyl group or a sulphonyl group;A represents a bivalent for trivalent saturated aliphatic hydrocarbon group;p is 1 (when A is bivalent) or 2 (when A is trivalent);R.sup.2 represents an azido, nitro or cyano group or one of the groups of formula ##STR2## m and n are the same or different and each is 0 or 1; R represents an amidino group or a group of formula R.sup.4, --N(R.sup.4).sub.2 or --YR.sup.4,B represents a group of formula ##STR3## D represents a group of formula ##STR4## (provided that, where m and n are both 1, the groups represented by B and D must be different);R.sup.4 represents a hydrogen atom or an alkyl group and, where there are 2 or more groups represented by R.sup.4, they may be the same or different, andY represents an oxygen atom or a sulphur atom; andR.sup.3 represents a carboxy group or a protected carboxy group)and pharmaceutically acceptable salts thereof are valuable antibiotics and may be prepared by a process which includes heating a corresponding phosphorus-ylide compound.
    • (I)的7-氧代-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸衍生物:其中:R 1表示氢原子或任选取代的烷基 组; X表示氧基,硫基,亚磺酰基或磺酰基; A代表三价饱和脂族烃基的二价; p为1(当A为二价时)或2(当A为三价时); R 2表示叠氮基,硝基或氰基,或者式中的一个基团m和n相同或不同,各自为0或1; R表示脒基或式R4,-N(R4)2或-YR4的基团,B表示式的基团D表示式的基团(条件是,其中m和n均为 1,由B和D表示的基团必须不同); R 4表示氢原子或烷基,其中,R 2表示2个以上基团时,可以相同或不同,Y表示氧原子或硫原子。 并且R 3表示羧基或保护的羧基)及其药学上可接受的盐是有价值的抗生素,并且可以通过包括加热相应的磷内酯化合物的方法来制备。