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91. 发明申请

US20050065560A1 Snoring detection system and method 有权
标题翻译：打鼾检测系统及方法
公开(公告)号：US20050065560A1
公开(公告)日：2005-03-24
申请号：US10943071
申请日：2004-09-15
申请人： Kent Lee , John Hatlestad , Jeffrey Stahmann , Jesse Hartley , Quan Ni , Krzysztof Siejko
发明人： Kent Lee , John Hatlestad , Jeffrey Stahmann , Jesse Hartley , Quan Ni , Krzysztof Siejko
IPC分类号： A61B5/08 , A61B5/113 , A61M16/00 , A61N1/08 , A61N1/40
CPC分类号： A61B5/4818 , A61B5/0809 , A61B5/113 , A61M16/026 , A61M2016/0021 , A61M2205/3375 , A61M2205/3553 , A61M2205/3584 , A61M2230/63 , A61N1/08
摘要： Systems and methods provide for detecting snoring, and for determining the presence of sleep disordered breathing using detected snoring. Snoring indicative signals generated by one or more patient-internal or external sensors are detected. The presence of sleep disordered breathing is algorithmically determined, patient-internally or externally, using the snoring signals. Algorithmically determining presence of sleep disordered breathing may include computing a snoring index developed from the detected snoring. Sleep apnea may be detected using the snoring index. Sleep apnea may be verified using internal or external sensors. A positive airway pressure device may operate cooperatively to verify and treat sleep disordered breathing.
摘要翻译：系统和方法提供检测打鼾，并使用检测到的打鼾来确定睡眠呼吸障碍的存在。检测由一个或多个患者内部或外部传感器产生的打鼾指示信号。睡眠无序呼吸的存在是使用打鼾信号在数学上由患者内部或外部确定的。算法确定睡眠呼吸障碍的存在可以包括计算从检测到的打鼾中产生的打鼾指数。可以使用打鼾指数检测睡眠呼吸暂停。可以使用内部或外部传感器验证睡眠呼吸暂停。正气道压力装置可以协同操作以验证和治疗睡眠呼吸紊乱。

92. 发明申请

US20050061315A1 Feedback system and method for sleep disordered breathing therapy 有权
标题翻译：睡眠紊乱呼吸治疗反馈系统及方法
公开(公告)号：US20050061315A1
公开(公告)日：2005-03-24
申请号：US10864287
申请日：2004-06-09
申请人： Kent Lee , Jesse Hartley , Jeffrey Stahmann , Quan Ni
发明人： Kent Lee , Jesse Hartley , Jeffrey Stahmann , Quan Ni
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/0215 , A61B5/0476 , A61B5/0488 , A61B5/11 , A61B7/00 , A61M16/00 , A61M15/00
CPC分类号： A61B5/0538 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/0476 , A61B5/0488 , A61B5/11 , A61B5/4818 , A61B7/003 , A61M16/024 , A61M2016/0021 , A61M2016/0039 , A61M2205/3523 , A61M2205/3561 , A61M2230/06 , A61M2230/50 , A61M2230/63 , G06F19/00
摘要： Methods and systems involve monitoring one or more patient conditions using a monitoring device that is fully or partially implantable. Feedback information is developed based on the monitored conditions and is provided to a device delivering therapy to treat sleep disordered breathing. Components of the monitoring device are disposed within an implantable housing that is separate from the housing of the therapy device. The therapy device may comprise a housing that is implantable or patient-external. The feedback information may be used to adjust the sleep disordered breathing therapy.
摘要翻译：方法和系统涉及使用完全或部分可植入的监测装置监测一个或多个患者状况。反馈信息是基于监测条件开发的，并提供给一个提供治疗以治疗睡眠呼吸紊乱的设备。监测装置的组件设置在与治疗装置的壳体分离的可植入壳体内。治疗装置可以包括可植入或患者外部的壳体。反馈信息可用于调节睡眠呼吸障碍治疗。

93. 发明申请

US20050043772A1 Therapy triggered by prediction of disordered breathing 有权
标题翻译：通过预测无序呼吸引发的治疗
公开(公告)号：US20050043772A1
公开(公告)日：2005-02-24
申请号：US10643154
申请日：2003-08-18
申请人： Jeffrey Stahmann , John Hatlestad , Quan Ni , Jesse Hartley , Douglas Daum , Kent Lee
发明人： Jeffrey Stahmann , John Hatlestad , Quan Ni , Jesse Hartley , Douglas Daum , Kent Lee
IPC分类号： A61N1/08 , A61N1/362 , A61N1/365 , A61N1/18
CPC分类号： A61N1/36514 , A61N1/3621 , A61N1/3627 , A61N1/3702
摘要： An approach to providing disordered breathing therapy includes providing therapy based on a prediction of disordered breathing. One or more patient conditions are detected and used to predict disordered breathing. Therapy is delivered to mitigate the predicted disordered breathing. The disordered breathing therapy may be adapted to enhance therapy efficacy and/or to reduce the impact of the therapy to the patient.
摘要翻译：提供无序呼吸治疗的方法包括基于无序呼吸预测提供治疗。检测一个或多个患者状况并用于预测无序呼吸。提供治疗以减轻预期的无序呼吸。无序的呼吸治疗可以适应于增强治疗功效和/或减少治疗对患者的影响。

94. 发明授权

US08521283B2 Trending of conduction time for optimization of cardiac resynchronization therapy in cardiac rhythm management system 有权
公开(公告)号：US08521283B2
公开(公告)日：2013-08-27
申请号：US11142165
申请日：2005-06-01
申请人： Andrew P. Kramer , Jeffrey Stahmann , Veerichetty A. Kadhiresan
发明人： Andrew P. Kramer , Jeffrey Stahmann , Veerichetty A. Kadhiresan
IPC分类号： A61N1/365
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/36542 , A61N1/3682 , A61N1/3684
摘要： A method of optimizing cardiac resynchronization therapy delay over a patient's full range of activity for use in operating an implantable cardiac pacing device and such a device are disclosed. The method includes measuring selected conduction time between selected sites in the heart for a plurality of beats and logging the values on a periodic repeating programmable basis to produce cumulative data and constructing a current template of conduction time in relation to one or more other sensed parameters of interest over a desired range of patient activity levels. The current template is used to derive suggested optimum pacing timing.

95. 发明申请

US20070129645A1 Determining blood gas saturation based on measured parameter of respiration 有权
标题翻译：根据呼吸测量参数确定血气饱和度
公开(公告)号：US20070129645A1
公开(公告)日：2007-06-07
申请号：US11291480
申请日：2005-12-01
申请人： Jesse Hartley , Jeffrey Stahmann , Kent Lee , Quan Ni
发明人： Jesse Hartley , Jeffrey Stahmann , Kent Lee , Quan Ni
IPC分类号： A61B5/08
CPC分类号： A61B5/0809 , A61B5/14546 , A61B5/4818
摘要： Systems and methods provide for determining blood gas saturation based on one or more measured respiration parameters. A parameter of respiration is measured implantably over a duration of time. The measured respiratory parameter is associated with a blood gas saturation level. Blood gas saturation is determined based on the measured respiration parameter. At least one of associating the measured respiratory parameter and determining blood gas saturation is preferably preformed implantably.
摘要翻译：系统和方法提供了基于一个或多个测量的呼吸参数来确定血液气体饱和度。在一段时间内可植入式地测量呼吸参数。测量的呼吸参数与血气饱和度水平相关。基于测量的呼吸参数确定血气饱和度。关联测量的呼吸参数和确定血液气体饱和度中的至少一个优选地可植入地预先形成。

96. 发明申请

US20070129643A1 Method and system for heart failure status evaluation based on a disordered breathing index 有权
标题翻译：基于无序呼吸指数的心衰状态评估方法和系统
公开(公告)号：US20070129643A1
公开(公告)日：2007-06-07
申请号：US11291525
申请日：2005-12-01
申请人： Jonathan Kwok , Marina Brockway , Kent Lee , Quan Ni , Yachuan Pu , Jeffrey Stahmann , Yi Zhang , Jesse Hartley
发明人： Jonathan Kwok , Marina Brockway , Kent Lee , Quan Ni , Yachuan Pu , Jeffrey Stahmann , Yi Zhang , Jesse Hartley
IPC分类号： A61B5/08 , A61B5/02
CPC分类号： A61B5/091 , A61B5/0031 , A61B5/0809 , A61B5/0816 , A61B5/113 , A61B5/4818 , A61N1/3627 , A61N1/36521 , A61N1/36535
摘要： An evaluation of heart failure status is provided based on a disordered breathing index. Patient respiration is sensed and a respiration signal is generated. Disordered breathing episodes are detected based on the respiration signal. A disordered breathing index is determined based on the disordered breathing episodes. The disordered breathing index is trended and used to evaluate heart failure status. The disordered breathing index may be combined with additional information and/or may take into account patient activity, posture, sleep stage, or other patient information.
摘要翻译：基于无序呼吸指数提供心力衰竭状态评估。感测患者呼吸并产生呼吸信号。基于呼吸信号检测到无序呼吸事件。基于无序呼吸发作确定无序呼吸指数。无序呼吸指数趋向并用于评估心力衰竭状态。无序呼吸指数可以与附加信息组合和/或可以考虑患者活动，姿势，睡眠阶段或其他患者信息。

97. 发明申请

US20070088220A1 Detection of hypovolemia using implantable medical device 有权
标题翻译：使用可植入医疗器械检测血容量不足
公开(公告)号：US20070088220A1
公开(公告)日：2007-04-19
申请号：US11249611
申请日：2005-10-13
申请人： Jeffrey Stahmann
发明人： Jeffrey Stahmann
IPC分类号： A61B5/02
CPC分类号： A61B5/02158 , A61B5/0031 , A61B5/0205 , A61N1/36557 , A61N1/36564
摘要： An implantable medical device receives a physiological signal indicative of circulatory blood volume and detects hypovolemia from that physiological signal. In one embodiment, an implantable pulmonary artery pressure (PAP) senses a PAP signal, and the implantable medical device detects hypovolemia from the PAP signal.
摘要翻译：可植入医疗装置接收指示循环血容量的生理信号，并从该生理信号检测血容量不足。在一个实施例中，可植入的肺动脉压（PAP）感测PAP信号，并且可植入医疗装置从PAP信号检测血容量不足。

98. 发明申请

US20070049978A1 PACING AND SENSING VECTORS 有权
标题翻译：遮光和感光矢量
公开(公告)号：US20070049978A1
公开(公告)日：2007-03-01
申请号：US11554135
申请日：2006-10-30
申请人： Jeffrey Stahmann , Bruce Tockman , Randy Westlund , Rene Wentkowski , Russell Anderson
发明人： Jeffrey Stahmann , Bruce Tockman , Randy Westlund , Rene Wentkowski , Russell Anderson
IPC分类号： A61N1/00
CPC分类号： A61N1/36514 , A61N1/3622 , A61N1/365 , A61N1/368 , A61N1/3712
摘要： A method for allowing cardiac signals to be sensed and pacing pulse vectors to be delivered between two or more electrodes. In one embodiment, cardiac signals are sensed and pacing pulse vectors are delivered between least one of a first left ventricular electrode and a second left ventricular electrode. Alternatively, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrodes and a first supraventricular electrode. In addition, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrode, the first supraventricular electrode and a conductive housing. In an additional embodiment, a first right ventricular electrode is used to sense cardiac signals and provide pacing pulses with different combinations of the first and second left ventricular electrodes, the first supraventricular electrode and the housing.
摘要翻译：一种用于允许感测心脏信号的方法和用于在两个或更多个电极之间递送起搏脉冲矢量的方法。在一个实施例中，感测心脏信号，并且起搏脉冲向量在第一左心室电极和第二左心室电极中的至少一个之间递送。或者，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极和第一室上电极的不同组合之间递送。此外，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极，第一室上电极和导电壳体的不同组合之间递送。在另外的实施例中，第一右心室电极用于感测心脏信号并且提供具有第一和第二左心室电极，第一室上电极和外壳的不同组合的起搏脉冲。

99. 发明申请

US20070005114A1 Therapy control based on the rate of change of intracardiac impedance 有权
标题翻译：基于心内阻抗变化率的治疗控制
公开(公告)号：US20070005114A1
公开(公告)日：2007-01-04
申请号：US11169339
申请日：2005-06-29
申请人： Rodney Salo , Joseph Pastore , Jeffrey Stahmann , Jesse Hartley
发明人： Rodney Salo , Joseph Pastore , Jeffrey Stahmann , Jesse Hartley
IPC分类号： A61N1/00
CPC分类号： A61N1/36521 , A61N1/30
摘要： A system comprising a medical device that includes an impedance measurement circuit adapted to be coupled to implantable electrodes to obtain an intracardiac impedance signal between electrodes, a therapy circuit operable to deliver a therapy to a subject, and a controller circuit coupled to the impedance measurement circuit and the therapy circuit. The controller circuit determines a time rate of change of the intracardiac impedance signal and adjusts at least one parameter related to therapy in a manner that alters the rate of change.
摘要翻译：一种包括医疗装置的系统，该医疗装置包括阻抗测量电路，该阻抗测量电路适于耦合到可植入电极以获得电极之间的心内阻抗信号，可操作以将治疗递送给受试者的治疗电路，以及耦合到所述阻抗测量电路和治疗电路。控制器电路确定心内阻抗信号的时间变化率，并且以改变变化率的方式调节与治疗相关的至少一个参数。

100. 发明申请

US20060271121A1 Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods 审中-公开
公开(公告)号：US20060271121A1
公开(公告)日：2006-11-30
申请号：US11136894
申请日：2005-05-25
申请人： Jiang Ding , Julio Spinelli , Yinghong Yu , Jeffrey Stahmann
发明人： Jiang Ding , Julio Spinelli , Yinghong Yu , Jeffrey Stahmann
IPC分类号： A61N1/368
CPC分类号： A61N1/3627 , A61B5/053 , A61N1/36521 , A61N1/3682 , A61N1/3684
摘要： This document discusses, among other things, systems, devices, and methods measure an impedance and, in response, adjust an atrioventricular (AV) delay or other cardiac resynchronization therapy (CRT) parameter that synchronizes left and right ventricular contractions. A first example uses parameterizes a first ventricular volume against a second ventricular volume during a cardiac cycle, using a loop area to create a synchronization fraction (SF). The CRT parameter is adjusted in closed-loop fashion to increase the SF. A second example measures a septal-freewall phase difference (PD), and adjusts a CRT parameter to decrease the PD. A third example measures a peak-to-peak volume or maximum rate of change in ventricular volume, and adjusts a CRT parameter to increase the peak-to-peak volume or maximum rate of change in the ventricular volume.

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