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1. 发明授权

US08224462B2 Medical lead system utilizing electromagnetic bandstop filters 有权
公开(公告)号：US08224462B2
公开(公告)日：2012-07-17
申请号：US13312741
申请日：2011-12-06
申请人： Randy Westlund , Robert A. Stevenson , Christine A. Frysz , Warren S. Dabney , Henry R. Halperin
发明人： Randy Westlund , Robert A. Stevenson , Christine A. Frysz , Warren S. Dabney , Henry R. Halperin
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/0534 , A61N1/0539 , A61N1/0556 , A61N1/0587 , A61N1/086 , A61N2001/0585 , H03H1/0007 , H03H2001/0042 , H03H2001/005 , H03H2007/013
摘要： Medical lead systems utilizing electromagnetic bandstop filters are provide which can be utilized in a magnetic resonance imaging (MRI) environment for patients who have implanted medical devices. The medical lead system includes an implanted lead having at least one bandstop filter associated therewith, for attenuating current flow through the lead over a range of frequencies. The bandstop filter has an overall circuit Q wherein the resultant 3 dB bandwidth is at least 10 kHz. The values of capacitance and inductance of the bandstop filter are selected such that the bandstop filter is resonant at a selected center frequency. Preferably, the bandstop filter has an overall circuit Q wherein the resultant 10 dB bandwidth is at least 10 kHz. Such bandstop filters are backwards compatible with known implantable deployment systems and extraction systems.

2. 发明申请

US20120083864A1 MEDICAL LEAD SYSTEM UTILIZING ELECTROMAGNETIC BANDSTOP FILTERS 审中-公开
公开(公告)号：US20120083864A1
公开(公告)日：2012-04-05
申请号：US13299278
申请日：2011-11-17
申请人： Randy Westlund , Robert A. Stevenson , Christine A. Frysz , Warren S. Dabney
发明人： Randy Westlund , Robert A. Stevenson , Christine A. Frysz , Warren S. Dabney
IPC分类号： A61N1/04
CPC分类号： A61N1/05 , A61N1/0534 , A61N1/0539 , A61N1/0556 , A61N1/0587 , A61N1/086 , A61N2001/0585 , H03H1/0007 , H03H7/0115 , H03H7/1766 , H03H2001/0085 , H03H2007/013
摘要： Medical lead systems utilizing electromagnetic bandstop filters are provide which can be utilized in a magnetic resonance imaging (MRI) environment for patients who have implanted medical devices. The medical lead system includes an implanted lead having at least one bandstop filter associated therewith, for attenuating current flow through the lead over a range of frequencies. The bandstop filter has an overall circuit Q wherein the resultant 3 dB bandwidth is at least 10 kHz. The values of capacitance and inductance of the bandstop filter are selected such that the bandstop filter is resonant at a selected center frequency. Preferably, the bandstop filter has an overall circuit Q wherein the resultant 10 dB bandwidth is at least 10 kHz. Such bandstop filters are backwards compatible with known implantable deployment systems and extraction systems.

3. 发明授权

US07875018B2 Method for manipulating an adjustable shape guide catheter 失效
标题翻译：用于操纵可调整导向导管的方法
公开(公告)号：US07875018B2
公开(公告)日：2011-01-25
申请号：US11027114
申请日：2004-12-30
申请人： Bruce Tockman , Randy Westlund
发明人： Bruce Tockman , Randy Westlund
IPC分类号： A61M31/00
CPC分类号： A61M25/0041 , A61M25/0105 , A61M25/0136
摘要： A method of manipulating a catheter assembly involves providing an inner catheter member movably disposed within an outer catheter member. At least a distal end portion of the inner catheter member has a stiffness greater than that of at least a distal end portion of the outer catheter member. The distal end portion of the outer catheter member includes a deflectable distal end. The method further involves advancing the inner catheter member through the outer catheter member toward the deflectable distal end of the outer catheter member, and longitudinally displacing the distal end portion of the inner catheter member relative to the deflectable distal end of the outer catheter member to alter a shape of the deflectable distal end.
摘要翻译：操作导管组件的方法包括提供可移动地设置在外导管构件内的内导管构件。至少内导管部件的远端部分的刚度大于外导管部件的至少远端部分的刚度。外导管构件的远端部分包括可偏转的远端。该方法还包括使内部导管构件通过外部导管构件朝向外部导管构件的可偏转远端推进，并且相对于外部导管构件的可偏转远端纵向移动内部导管构件的远端部分以改变可偏转的远端的形状。

4. 发明授权

US07657324B2 Seal for use with cardiac lead 失效
标题翻译：密封用于心脏铅
公开(公告)号：US07657324B2
公开(公告)日：2010-02-02
申请号：US10617881
申请日：2003-07-14
申请人： Randy Westlund , Bruce Tockman , Gwen Crevensten , Lili Liu , Christopher M. Zerby
发明人： Randy Westlund , Bruce Tockman , Gwen Crevensten , Lili Liu , Christopher M. Zerby
IPC分类号： A61N1/05
CPC分类号： A61N1/0565 , A61N1/056 , A61N1/0573
摘要： A seal adapted for use with medical devices is provided. The medical device may be a lead having a distal tip adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead assembly in one embodiment includes an atraumatic tip. A seal is provided within the lead tip assembly, which prevents or limits further entry of fluids through the lead tip. The lead may be a left ventricular lead with a hemostasis mechanism provided therewithin.
摘要翻译：提供适于与医疗装置一起使用的密封件。医疗装置可以是具有适于植入在心脏上或周围的远端的引线，并且用于连接到用于监测或刺激心脏活动的系统。在一个实施例中的引线组件包括无创伤的尖端。在引线端头组件内提供密封件，其防止或限制流体进一步进入引线尖端。铅可以是在其中设置有止血机构的左心室导联。

5. 发明授权

US07628801B2 Coronary vein leads having an atraumatic tip and method therefor 有权
标题翻译：冠状静脉引导具有无创伤的尖端及其方法
公开(公告)号：US07628801B2
公开(公告)日：2009-12-08
申请号：US10128997
申请日：2002-04-23
申请人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61F7/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having an atraumatic tip is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by a preformed biased portion. Near the distal end, the lead has an optional tapered portion and a flexible portion, where the flexible portion is more flexible than the biased portion.
摘要翻译：具有无创尖端的引线适于植入在冠状脉管系统内或心脏周围并用于连接到信号发生器。引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先偏置的部分偏压到血管壁。在远端附近，引线具有可选的锥形部分和柔性部分，其中柔性部分比偏置部分更柔性。

6. 发明申请

US20080234780A1 SELECTIVE NERVE STIMULATION WITH OPTIONALLY CLOSED-LOOP CAPABILITIES 有权
标题翻译：选择性神经刺激具有可选的闭环能力
公开(公告)号：US20080234780A1
公开(公告)日：2008-09-25
申请号：US11687809
申请日：2007-03-19
申请人： David J. Smith , Randy Westlund , Imad Libbus
发明人： David J. Smith , Randy Westlund , Imad Libbus
IPC分类号： A61N1/05
CPC分类号： A61N1/36139 , A61N1/36071 , A61N1/36114 , A61N1/36185
摘要： Systems and methods for steering one or more stimulation fields to a selected nerve target, thereby optimizing one or a combination of low stimulation thresholds, desired therapy outcomes, or a minimization of adverse stimulation side-effects. An array of electrodes disposed, at least in part, on two or more neural stimulation leads are used for steering the stimulation fields to the selected nerve target and are positioned adjacent the selected target. The stimulation may be titrated based on, among other things, a detected physiologic response to the applied stimulation.
摘要翻译：用于将一个或多个刺激场转向所选择的神经靶的系统和方法，从而优化低刺激阈值，期望的治疗结果或不利刺激副作用的最小化中的一个或组合。使用至少部分地设置在两个或更多个神经刺激引线上的电极阵列，用于将刺激场转向所选择的神经靶，并且定位成与所选择的靶相邻。基于对所施加的刺激的检测到的生理反应，刺激可以被滴定。

7. 发明授权

US07412290B2 Seal for use with medical device and system 失效
标题翻译：用于医疗器械和系统的密封
公开(公告)号：US07412290B2
公开(公告)日：2008-08-12
申请号：US10968305
申请日：2004-10-20
申请人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
发明人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
IPC分类号： A61N1/372
CPC分类号： A61N1/0573 , A61N1/0565
摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.
摘要翻译：适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。引线可以包括用于将电极固定到心脏组织的固定螺旋。导线组件可以替代地包括开放的管腔引线端头。在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。密封件包括可膨胀基质，例如水凝胶。当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

8. 发明申请

US20080058874A1 METHOD AND APPARATUS FOR OPTIMIZING VAGAL NERVE STIMULATION USING LARYNGEAL ACTIVITY 有权
标题翻译：使用Larynge活动优化VAGAL神经刺激的方法和装置
公开(公告)号：US20080058874A1
公开(公告)日：2008-03-06
申请号：US11469551
申请日：2006-09-01
申请人： Randy Westlund , Anthony V. Caparso , Mark Bly
发明人： Randy Westlund , Anthony V. Caparso , Mark Bly
IPC分类号： A61N1/18
CPC分类号： A61N1/36053 , A61B5/04001 , A61B5/0402 , A61B5/1104 , A61B5/6822 , A61B5/7203 , A61N1/0551 , A61N1/36114 , A61N1/36542 , A61N1/37247 , A61N1/37288
摘要： A neural stimulation system delivers neural stimulation to the vagus nerve and senses a signal indicative of laryngeal activity resulting from the neural stimulation. The signal indicative of laryngeal activity is used, for example, to guide electrode placement, determine stimulation threshold, detect lead/electrode problems, detect neural injury, and monitor healing processing following the electrode placement inside the body of a patient.
摘要翻译：神经刺激系统将神经刺激传递给迷走神经，并感测到指示由神经刺激引起的喉部活动的信号。例如，使用指示喉部活动的信号来引导电极放置，确定刺激阈值，检测铅/电极问题，检测神经损伤，以及在患者体内的电极放置之后监测愈合过程。

9. 发明申请

US20070067008A1 Leads for pacing and/or sensing the heart from within the coronary veins 审中-公开
标题翻译：引导在冠状静脉内起搏和/或感测心脏
公开(公告)号：US20070067008A1
公开(公告)日：2007-03-22
申请号：US11600807
申请日：2006-11-16
申请人： Avram Scheiner , Ronald Heil , Peter Kelley , Bruce Tockman , Randy Westlund , Jay Warren
发明人： Avram Scheiner , Ronald Heil , Peter Kelley , Bruce Tockman , Randy Westlund , Jay Warren
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead for monitoring or stimulating cardiac activity is provided. The lead is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead body has one or more electrodes associated therewith. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and urged into intimate contact a vessel wall.
摘要翻译：提供监测或刺激心脏活动的潜在客户。引线适于植入在冠状脉管系统内部或其周围的心脏上，并用于连接到信号发生器。引线体具有与其相关联的一个或多个电极。导线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并被促使与血管壁紧密接触。

10. 发明申请

US20070049978A1 PACING AND SENSING VECTORS 有权
标题翻译：遮光和感光矢量
公开(公告)号：US20070049978A1
公开(公告)日：2007-03-01
申请号：US11554135
申请日：2006-10-30
申请人： Jeffrey Stahmann , Bruce Tockman , Randy Westlund , Rene Wentkowski , Russell Anderson
发明人： Jeffrey Stahmann , Bruce Tockman , Randy Westlund , Rene Wentkowski , Russell Anderson
IPC分类号： A61N1/00
CPC分类号： A61N1/36514 , A61N1/3622 , A61N1/365 , A61N1/368 , A61N1/3712
摘要： A method for allowing cardiac signals to be sensed and pacing pulse vectors to be delivered between two or more electrodes. In one embodiment, cardiac signals are sensed and pacing pulse vectors are delivered between least one of a first left ventricular electrode and a second left ventricular electrode. Alternatively, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrodes and a first supraventricular electrode. In addition, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrode, the first supraventricular electrode and a conductive housing. In an additional embodiment, a first right ventricular electrode is used to sense cardiac signals and provide pacing pulses with different combinations of the first and second left ventricular electrodes, the first supraventricular electrode and the housing.
摘要翻译：一种用于允许感测心脏信号的方法和用于在两个或更多个电极之间递送起搏脉冲矢量的方法。在一个实施例中，感测心脏信号，并且起搏脉冲向量在第一左心室电极和第二左心室电极中的至少一个之间递送。或者，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极和第一室上电极的不同组合之间递送。此外，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极，第一室上电极和导电壳体的不同组合之间递送。在另外的实施例中，第一右心室电极用于感测心脏信号并且提供具有第一和第二左心室电极，第一室上电极和外壳的不同组合的起搏脉冲。

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