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1. 发明申请

US20070100332A1 Systems and methods for electrode contact assessment 有权
标题翻译：电极接触评估的系统和方法
公开(公告)号：US20070100332A1
公开(公告)日：2007-05-03
申请号：US11553965
申请日：2006-10-27
申请人： Saurav Paul , Troy Tegg , Chou Thao , Hong Cao , Harry Puryear , Fos Kuehn , Reed Heimbecher
发明人： Saurav Paul , Troy Tegg , Chou Thao , Hong Cao , Harry Puryear , Fos Kuehn , Reed Heimbecher
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B5/6852 , A61B5/6885 , A61B2090/065
摘要： Systems and methods are disclosed for assessing electrode-tissue contact for tissue ablation. An exemplary electrode contact sensing system comprises an electrode housed within a distal portion of a catheter shaft. At least one electro-mechanical sensor is operatively associated with the electrode within the catheter shaft. The at least one electro-mechanical sensor is responsive to movement of the electrode by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one electro-mechanical sensor. The output device receives the electrical signals for assessing a level of contact between the electrode and a tissue.
摘要翻译：公开了用于评估用于组织消融的电极组织接触的系统和方法。示例性电极接触感测系统包括容纳在导管轴的远端部分内的电极。至少一个机电传感器与导管轴内的电极可操作地相关联。所述至少一个机电传感器通过产生对应于移动量的电信号来响应电极的运动。该系统还可以包括电连接到该至少一个机电传感器的输出装置。输出装置接收用于评估电极和组织之间的接触水平的电信号。

2. 发明授权

US08021361B2 Systems and methods for electrode contact assessment 有权
标题翻译：电极接触评估的系统和方法
公开(公告)号：US08021361B2
公开(公告)日：2011-09-20
申请号：US11553965
申请日：2006-10-27
申请人： Saurav Paul , Troy Tegg , Chou Thao , Hong Cao , Harry A. Puryear , Fos Kuehn , Reed R. Heimbecher
发明人： Saurav Paul , Troy Tegg , Chou Thao , Hong Cao , Harry A. Puryear , Fos Kuehn , Reed R. Heimbecher
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B5/6852 , A61B5/6885 , A61B2090/065
摘要： Systems and methods are disclosed for assessing electrode-tissue contact for tissue ablation. An exemplary electrode contact sensing system comprises an electrode housed within a distal portion of a catheter shaft. At least one electro-mechanical sensor is operatively associated with the electrode within the catheter shaft. The at least one electro-mechanical sensor is responsive to movement of the electrode by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one electro-mechanical sensor. The output device receives the electrical signals for assessing a level of contact between the electrode and a tissue.
摘要翻译：公开了用于评估用于组织消融的电极组织接触的系统和方法。示例性电极接触感测系统包括容纳在导管轴的远端部分内的电极。至少一个机电传感器与导管轴内的电极可操作地相关联。所述至少一个机电传感器通过产生对应于移动量的电信号来响应电极的运动。该系统还可以包括电连接到该至少一个机电传感器的输出装置。输出装置接收用于评估电极和组织之间的接触水平的电信号。

3. 发明授权

US08162935B2 Systems and methods for electrode contact assessment 有权
标题翻译：电极接触评估的系统和方法
公开(公告)号：US08162935B2
公开(公告)日：2012-04-24
申请号：US12091151
申请日：2006-10-27
申请人： Saurav Paul , Troy T. Tegg , Chou Thao , Hong Cao , Harry Puryear , Fos Kuehn , Reed R. Heimbecher
发明人： Saurav Paul , Troy T. Tegg , Chou Thao , Hong Cao , Harry Puryear , Fos Kuehn , Reed R. Heimbecher
IPC分类号： A61B18/14 , A61B5/04
CPC分类号： A61B18/1492 , A61B5/6852 , A61B5/6885 , A61B2090/065
摘要： Systems and methods are disclosed for assessing electrode-tissue contact for tissue ablation. An exemplary electrode contact sensing system comprises an electrode 10 housed within a distal portion of a catheter shaft 14. At least one electro-mechanical sensor 20 is operatively associated with the electrode 10 within the catheter shaft 14. The at least one electro-mechanical sensor 20 is responsive to movement of the electrode 10 by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one electro-mechanical sensor 20. The output device receives the electrical signals for assessing a level of contact between the electrode 10 and a tissue 12.
摘要翻译：公开了用于评估用于组织消融的电极组织接触的系统和方法。示例性的电极接触感测系统包括容纳在导管轴14的远端部分内的电极10.至少一个电 - 机械传感器20与导管轴14内的电极10可操作地相关联。至少一个电 - 机械传感器 20通过产生对应于移动量的电信号来响应于电极10的运动。该系统还可以包括电连接到至少一个机电传感器20的输出装置。输出装置接收用于评估电极10和组织12之间的接触程度的电信号。

4. 发明申请

US20080275442A1 Systems and Methods for Electrode Contact Assessment 有权
标题翻译：电极接触评估系统与方法
公开(公告)号：US20080275442A1
公开(公告)日：2008-11-06
申请号：US12091151
申请日：2006-10-27
申请人： Saurav Paul , Troy T. Tegg , Chou Thao , Hong Cao , Harry Puryear , Fos Kuehn , Reed R. Heimbecher
发明人： Saurav Paul , Troy T. Tegg , Chou Thao , Hong Cao , Harry Puryear , Fos Kuehn , Reed R. Heimbecher
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B5/6852 , A61B5/6885 , A61B2090/065
摘要： Systems and methods are disclosed for assessing electrode-tissue contact for tissue ablation. An exemplary electrode contact sensing system comprises an electrode 10 housed within a distal portion of a catheter shaft 14. At least one electromechanical sensor 20 is operatively associated with the electrode 10 within the catheter shaft 14. The at least one electromechanical sensor 20 is responsive to movement of the electrode 10 by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one electromechanical sensor 20. The output device receives the electrical signals for assessing a level of contact between the electrode 10 and a tissue 12.
摘要翻译：公开了用于评估用于组织消融的电极组织接触的系统和方法。示例性电极接触感测系统包括容纳在导管轴14的远端部分内的电极10。至少一个机电传感器20与导管轴14内的电极10可操作地相关联。至少一个机电传感器20通过产生对应于移动量的电信号来响应电极10的运动。该系统还可以包括电连接到至少一个机电传感器20的输出装置。输出装置接收用于评估电极10和组织12之间的接触水平的电信号。

5. 发明申请

US20080015568A1 Dynamic contact assessment for electrode catheters 有权
标题翻译：电极导管的动态接触评估
公开(公告)号：US20080015568A1
公开(公告)日：2008-01-17
申请号：US11549100
申请日：2006-10-12
申请人： Saurav Paul , Chou Thao , Kedar Belhe , Reed Heimbecher
发明人： Saurav Paul , Chou Thao , Kedar Belhe , Reed Heimbecher
IPC分类号： A61B18/18
CPC分类号： A61B5/036 , A61B5/061 , A61B5/6885 , A61B18/1492 , A61B2018/00351 , A61B2090/065
摘要： An electrode catheter and a method for assessing catheter-tissue contact for tissue ablation are disclosed. An exemplary electrode catheter comprises a flexible catheter shaft. At least one piezoelectric sensor is oriented coaxial to the flexible catheter shaft. The at least one piezoelectric sensor is responsive to movement of the flexible catheter shaft by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one piezoelectric sensor. The output device receives the electrical signals for dynamically assessing a level of contact between the flexible catheter shaft and a moving tissue. In another exemplary embodiment, the system may be implemented in a hydrodynamic environment.
摘要翻译：公开了电极导管和用于评估用于组织消融的导管 - 组织接触的方法。示例性电极导管包括柔性导管轴。至少一个压电传感器与柔性导管轴同轴地定向。至少一个压电传感器通过产生对应于移动量的电信号来响应柔性导管轴的移动。该系统还可以包括电连接到至少一个压电传感器的输出装置。输出装置接收用于动态评估柔性导管轴和移动组织之间的接触程度的电信号。在另一个示例性实施例中，系统可以在流体动力学环境中实现。

6. 发明申请

US20090171188A1 FLEXIBLE POLYMER ELECTRODE FOR MRI-GUIDED POSITIONING AND RADIO FREQUENCY ABLATION 有权
标题翻译：用于MRI引导定位和无线电频率消除的柔性聚合物电极
公开(公告)号：US20090171188A1
公开(公告)日：2009-07-02
申请号：US11966576
申请日：2007-12-28
申请人： Saurav Paul , Troy T. Tegg , Chou Thao , Harry Puryear
发明人： Saurav Paul , Troy T. Tegg , Chou Thao , Harry Puryear
IPC分类号： A61B5/055
CPC分类号： A61B18/1492 , A61B5/055 , A61B5/06 , A61B2018/00702 , A61B2018/00791 , A61B2018/00815 , A61B2034/2068 , A61B2090/374 , A61B2090/3954
摘要： An electrode for use on a medical device is disclosed. The electrode may have a main body of electrically conductive material extending along an axis and may have a proximal end and a distal end. The electrode may also include a magnetic resonance imaging (MRI) tracking coil disposed in the body. The MRI tracking coil may comprise electrically insulated wire. A catheter including an electrode, as well as a method for determining the location of an electrode, are also disclosed.
摘要翻译：公开了一种用于医疗装置的电极。电极可以具有沿着轴线延伸的导电材料的主体，并且可以具有近端和远端。电极还可以包括设置在体内的磁共振成像（MRI）跟踪线圈。 MRI跟踪线圈可以包括电绝缘线。还公开了包括电极的导管以及用于确定电极位置的方法。

7. 发明授权

US09675410B2 Flexible polymer electrode for MRI-guided positioning and radio frequency ablation 有权
公开(公告)号：US09675410B2
公开(公告)日：2017-06-13
申请号：US11966576
申请日：2007-12-28
申请人： Saurav Paul , Troy T. Tegg , Chou Thao , Harry Puryear
发明人： Saurav Paul , Troy T. Tegg , Chou Thao , Harry Puryear
IPC分类号： A61B5/05 , A61B18/14 , A61B5/055 , A61B5/06 , A61B18/00 , A61B34/20 , A61B90/00
CPC分类号： A61B18/1492 , A61B5/055 , A61B5/06 , A61B2018/00702 , A61B2018/00791 , A61B2018/00815 , A61B2034/2068 , A61B2090/374 , A61B2090/3954
摘要： An electrode for use on a medical device is disclosed. The electrode may have a main body of electrically conductive material extending along an axis and may have a proximal end and a distal end. The electrode may also include a magnetic resonance imaging (MRI) tracking coil disposed in the body. The MRI tracking coil may comprise electrically insulated wire. A catheter including an electrode, as well as a method for determining the location of an electrode, are also disclosed.

8. 发明授权

US08226648B2 Pressure-sensitive flexible polymer bipolar electrode 有权
标题翻译：压敏柔性聚合物双极电极
公开(公告)号：US08226648B2
公开(公告)日：2012-07-24
申请号：US11968044
申请日：2007-12-31
申请人： Saurav Paul , Harry Puryear , Chou Thao
发明人： Saurav Paul , Harry Puryear , Chou Thao
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/1206 , A61B2018/00023 , A61B2018/00577 , A61B2018/00875
摘要： The present invention is directed to bipolar ablation systems. A bipolar electrode system for ablation therapy is disclosed, including a pressure-sensitive conducting composite layer and a pair of electrodes in electrical conductive contact or communication with the pressure-sensitive conducting composite layer. Energy (e.g., ablation energy) is delivered via the pressure-sensitive conductive composition when sufficient pressure is applied to transform the pressure-sensitive conductive composite to an electrical conductor. An electrically insulative flexible layer, which may include a passageway for a fill material is also disclosed. In some embodiments, the systems can also be used for targeted delivery of compounds, such as drugs, using a bipolar electrode.
摘要翻译：本发明涉及双相消融系统。公开了一种用于消融治疗的双极电极系统，包括压敏导电复合层和一对导电接触或与压敏导电复合层连通的电极。当施加足够的压力以将压敏导电复合材料转变成电导体时，能量（例如，消融能量）经由压敏导电组合物递送。还公开了可以包括用于填充材料的通道的电绝缘柔性层。在一些实施方案中，所述系统也可用于使用双极电极靶向递送化合物，例如药物。

9. 发明授权

US09283025B2 Assessment of electrode coupling for tissue ablation 有权
公开(公告)号：US09283025B2
公开(公告)日：2016-03-15
申请号：US12095701
申请日：2006-12-06
申请人： Saurav Paul , Kedar Ravindra Belhe , Hong Cao , Chou Thao
发明人： Saurav Paul , Kedar Ravindra Belhe , Hong Cao , Chou Thao
IPC分类号： A61B18/12 , A61B18/14 , A61B19/00 , A61B18/00
CPC分类号： A61B18/1206 , A61B18/1492 , A61B34/20 , A61B2018/00303 , A61B2018/00357 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00702 , A61B2018/0075 , A61B2018/00755 , A61B2018/00869 , A61B2018/00875 , A61B2090/064 , A61B2090/065
摘要： An electrode catheter and a method for assessing electrode-tissue contact and coupling are disclosed. An exemplary electrode catheter comprises an electrode adapted to apply electrical energy. A measurement circuit is adapted to measure impedance between the electrode and ground as the electrode approaches a target tissue. A processor determines a contact and coupling condition for the target tissue based at least in part on reactance of the impedance measured by the measurement circuit. In another exemplary embodiment, the electrode catheter determines the contact and coupling condition based at least in part on a phase angle of the impedance.

10. 发明授权

US08449537B2 Ablation catheter with thermally mediated catheter body for mitigating blood coagulation and creating larger lesion 有权
标题翻译：消融导管与热介导的导管体减轻血液凝固和创造更大的病变
公开(公告)号：US08449537B2
公开(公告)日：2013-05-28
申请号：US11618692
申请日：2006-12-29
申请人： Hong Cao , Xiaoping Guo , Isaac Shai , Michael Yang , Kedar Ravindra Belhe , Saurav Paul , Chou Thao
发明人： Hong Cao , Xiaoping Guo , Isaac Shai , Michael Yang , Kedar Ravindra Belhe , Saurav Paul , Chou Thao
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2018/00005 , A61B2018/00357
摘要： An ablation catheter is provided for ablating internal tissue of a patient. The catheter includes a distal end that is adapted to be inserted into a body cavity relative to a desired location therein (e.g., within the heart). An ablation electrode is connected relative to the distal end of the catheter for providing ablation energy to patient tissue. A heat sink is provided that is in thermal contact with the ablation electrode. The heat sink, in addition to being in thermal contact with the ablation electrode, is electrically isolated from the ablation electrode. This allows the heat sink to conduct heat away from the ablation electrode without dissipating electrical energy from the electrode. In this regard, the heat sink may prevent build-up of excess heat within the electrode that may result in blood coagulation and/or tissue charring.
摘要翻译：提供消融导管以消融患者的内部组织。该导管包括适于相对于其中的期望位置（例如，在心脏内）插入体腔内的远端。消融电极相对于导管的远端连接，以向患者组织提供消融能量。提供与消融电极热接触的散热器。除了与消融电极热接触之外，散热器与消融电极电隔离。这允许散热器将热量从消融电极导出，而不会从电极中消耗电能。在这方面，散热器可以防止在电极内积聚多余的热量，从而导致血液凝固和/或组织烧焦。

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