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1. 发明授权

US09289606B2 System for electroporation therapy 有权
标题翻译：电穿孔治疗系统
公开(公告)号：US09289606B2
公开(公告)日：2016-03-22
申请号：US12874788
申请日：2010-09-02
申请人： Saurav Paul , Troy T. Tegg , Israel A. Byrd , Riki Thao , Harry A. Puryear , Linda Nemec , John M. Berns
发明人： Saurav Paul , Troy T. Tegg , Israel A. Byrd , Riki Thao , Harry A. Puryear , Linda Nemec , John M. Berns
IPC分类号： A61B18/18 , A61N1/32 , A61B18/14 , A61B18/00
CPC分类号： A61N1/327 , A61B18/14 , A61B2018/0016
摘要： Catheter systems include direction-sensitive, multi-polar tip electrode assemblies for electroporation-mediated therapy, electroporation-induced primary necrosis therapy and electric field-induced apoptosis therapy, including configurations for producing narrow, linear lesions as well as distributed, wide area lesions. A monitoring system for electroporation therapy includes a mechanism for delivering electrochromic dyes to a tissue site as well as a fiber optic arrangement to optically monitor the progress of the therapy as well as to confirm success post-therapy. A fiber optic temperature sensing electrode catheter includes a tip electrode having a cavity whose inner surface is impregnated or coated with thermochromic/thermotropic material that changes color with changes in temperature. An optic fiber/detector arrangement monitors the thermochromic or thermotropic materials, acquiring a light signal and generating an output signal indicative of the spectrum of the light signal. An analyzer determines an electrode temperature based on the detector output and predetermined spectrum versus temperature calibration data.
摘要翻译：导管系统包括用于电穿孔介导治疗的方向敏感的多极尖端电极组件，电穿孔诱导的原发性坏死治疗和电场诱导的凋亡治疗，包括用于产生狭窄的线性损伤以及分布的广泛区域损伤的构造。用于电穿孔治疗的监测系统包括将电致变色染料递送到组织部位的机制以及光学配置以光学监测治疗进展以及确认疗法后的成功。光纤温度感测电极导管包括具有腔体的尖端电极，其内表面被浸渍或涂覆有随着温度变化而改变颜色的热变色/热致变色材料。光纤/检测器装置监测热致变色或热致变色材料，获取光信号并产生指示光信号光谱的输出信号。分析仪基于检测器输出和预定的频谱对温度校准数据来确定电极温度。

2. 发明授权

US09023033B2 Magnetically guided catheters 有权
标题翻译：磁导引导管
公开(公告)号：US09023033B2
公开(公告)日：2015-05-05
申请号：US12850485
申请日：2010-08-04
申请人： Troy T. Tegg , James V. Kauphusman
发明人： Troy T. Tegg , James V. Kauphusman
IPC分类号： A61B18/12 , A61M25/01 , A61B5/042 , A61B5/06 , A61B5/00 , A61B18/14 , A61B18/00 , A61B19/00
CPC分类号： A61B18/1492 , A61B5/0422 , A61B5/062 , A61B5/6852 , A61B34/20 , A61B34/70 , A61B34/73 , A61B2018/00011 , A61B2018/00029 , A61B2018/00577 , A61B2034/2051 , A61B2218/002 , A61M25/0127 , A61M25/0158 , A61M2025/0166 , Y10T29/49117
摘要： A magnetically-guided catheter includes a tip positioning magnet in the distal electrode assembly configured to interact with externally applied magnetic fields for magnetically-guided movement. A magnetically-guided mapping catheter includes an electrically-conductive capsule in the form of a casing that includes a distal ablation surface and isolates the positioning magnet from bio-fluids to prevent corrosion. An open irrigation ablation catheter includes an isolated manifold that isolates the positioning magnet from contact with irrigation fluid to prevent corrosion.
摘要翻译：磁导引导管包括在远端电极组件中的尖端定位磁体，该尖端定位磁体配置成与外部施加的磁场相互作用以进行磁引导运动。磁导引映射导管包括壳体形式的导电胶囊，其包括远端消融表面，并将定位磁体与生物流体隔离以防止腐蚀。开放灌溉消融导管包括隔离的歧管，其将定位磁体与冲洗流体接触以防止腐蚀。

3. 发明授权

US08945118B2 Catheter with flexible tether and introducer for a catheter 有权
标题翻译：导管带有灵活的系绳和引导器用于导管
公开(公告)号：US08945118B2
公开(公告)日：2015-02-03
申请号：US12850494
申请日：2010-08-04
申请人： Troy T. Tegg
发明人： Troy T. Tegg
IPC分类号： A61B18/12 , A61B5/06 , A61M25/01 , A61B18/00
CPC分类号： A61B5/068 , A61B5/062 , A61B2018/00011 , A61B2018/00577 , A61M25/0127 , A61M25/0158
摘要： A magnetically-guided catheter includes a tip positioning magnet in the distal electrode assembly configured to interact with externally applied magnetic fields for magnetically-guided movement. A magnetically-guided mapping catheter includes an electrically-conductive capsule in the form of a casing that includes a distal ablation surface and isolates the positioning magnet from bio-fluids to prevent corrosion. An open irrigation ablation catheter includes an isolated manifold that isolates the positioning magnet from contact with irrigation fluid to prevent corrosion. A device and method to manufacture a magnetically driven electrode-catheter with flexible tethering includes one or more KEVLAR® fibers, distributed centrally or peripherally within a catheter shaft and oriented longitudinally, transversely, angularly or spirally. A C-shaped extruded catheter introducer (and re-introducer) includes a longitudinally-extending opening for insertion of a magnetically-guided catheter, removal of the introducer from the catheter and which is constructed to facilitate its re-use in a medical procedure.
摘要翻译：磁导引导管包括在远端电极组件中的尖端定位磁体，该尖端定位磁体配置成与外部施加的磁场相互作用以进行磁引导运动。磁导引映射导管包括壳体形式的导电胶囊，其包括远端消融表面，并将定位磁体与生物流体隔离以防止腐蚀。开放灌溉消融导管包括隔离的歧管，其将定位磁体与冲洗流体接触以防止腐蚀。用于制造具有柔性束带的磁驱动电极导管的装置和方法包括一个或多个KEFLAR纤维，其分布在导管轴中心或外周并且纵向，横向，角度或螺旋地定向。 C形挤出导管导引器（和重新引导器）包括用于插入导磁导管的纵向延伸的开口，导管从导管中移除，并且构造成便于其在医疗过程中重复使用。

4. 发明申请

US20140121595A1 PUSH-COIL STEERING MECHANISM 有权
标题翻译：推卷机转向机构
公开(公告)号：US20140121595A1
公开(公告)日：2014-05-01
申请号：US13663569
申请日：2012-10-30
申请人： Troy T. Tegg
发明人： Troy T. Tegg
IPC分类号： A61M25/092
CPC分类号： A61M25/0147 , A61B1/00133 , A61M25/0136 , A61M2025/015
摘要： A handle assembly is provided for use in navigating a deformable shaft within a body. The assembly includes a first guide member defining first and second linear channels and a second guide member configured for rotation relative to the first guide member. First and second connectors are disposed within, and movable within, the first and second linear channels along first and second parallel axes, respectively, and are configured for coupling to first and second steering wires, respectively. The assembly includes means, such as a flexible coupling connected to the second guide member and the connectors, for translating rotation of the second guide member into linear movement of the first connector in a first axial direction and linear movement of the second connector in a second axial direction, opposite the first axial direction such that the first and second steering wires move in opposite directions.
摘要翻译：手柄组件设置用于导航体内的可变形轴。组件包括限定第一和第二线性通道的第一引导构件和被配置为相对于第一引导构件旋转的第二引导构件。第一和第二连接器分别设置在沿着第一和第二平行轴线的第一和第二线性通道内并在其中可移动，并且分别构造成用于联接到第一和第二操纵线。组件包括诸如连接到第二引导构件和连接器的柔性联接器的装置，用于将第二引导构件的旋转在第一轴向方向上平移到第一连接器的线性运动，并且第二连接器在第二轴线方向上的线性运动轴向，与第一轴向方向相反，使得第一和第二操纵线沿相反方向移动。

5. 发明授权

US08684999B2 Catheter shaft and method of manufacture 有权
标题翻译：导管轴及制造方法
公开(公告)号：US08684999B2
公开(公告)日：2014-04-01
申请号：US11967784
申请日：2007-12-31
申请人： Troy T. Tegg , Richard E. Stehr , Allan M. Fuentes , Linda K. Nemec
发明人： Troy T. Tegg , Richard E. Stehr , Allan M. Fuentes , Linda K. Nemec
IPC分类号： A61M25/00 , B29D22/00 , B29D23/00 , B32B1/08
CPC分类号： A61M25/005 , A61M25/0009 , A61M25/0043 , A61M25/0045 , F16L11/085
摘要： A method of manufacturing a catheter assembly generally includes providing a catheter shaft having an outer layer and an inner reinforcing layer; removing at least a portion of the outer layer from a length of the distal end of the catheter shaft in order to expose a distal segment thereof; providing an inner jacket segment; axially engaging the inner jacket segment with an interior surface of the distal segment of the catheter shaft; providing an outer jacket segment around at least the exposed exterior region of the distal segment of the catheter shaft; and bonding the distal segment of the catheter shaft to the inner jacket segment and the outer jacket segment.
摘要翻译：制造导管组件的方法通常包括提供具有外层和内增强层的导管轴; 从所述导管轴的远端的长度移除所述外层的至少一部分，以暴露其远端段; 提供内护套部分; 将内护套段与导管轴的远端段的内表面轴向接合; 提供围绕所述导管轴的远端段的暴露的外部区域的外护套段; 以及将导管轴的远端部分结合到内护套部分和外护套部分。

6. 发明授权

US08577447B2 Optic-based contact sensing assembly and system 有权
标题翻译：基于光学的接触感测组件和系统
公开(公告)号：US08577447B2
公开(公告)日：2013-11-05
申请号：US11941073
申请日：2007-11-15
申请人： Troy T. Tegg , Saurav Paul , Richard E. Stehr , Reed R. Heimbecher
发明人： Troy T. Tegg , Saurav Paul , Richard E. Stehr , Reed R. Heimbecher
IPC分类号： A61B18/14
CPC分类号： A61B5/6885 , A61B5/0084 , A61B5/6852 , A61B5/6886 , A61B18/1492 , A61B18/24 , A61B2017/00057 , A61B2017/00084 , A61B2090/065 , A61M25/0069 , A61M25/007 , A61M25/0071 , A61M2025/0002
摘要： The invention relates to an optic-based sensing assembly and a system incorporating the assembly and related use of the assembly. In particular, the invention relates to an optic-based catheter assembly and related system used to determine contact between a catheter and surrounding proximate environment, such as tissue. An embodiment of such a system may, for example, be used for visualization, mapping, ablation, or other methods of diagnosis and treatment of tissue and/or surrounding areas.
摘要翻译：本发明涉及一种基于光学的感测组件以及结合该组件的组件和该组件的相关使用的系统。特别地，本发明涉及一种基于光学的导管组件和相关系统，其用于确定导管和周围的近处环境（例如组织）之间的接触。这种系统的实施例可以例如用于组织和/或周围区域的可视化，映射，消融或其它诊断和治疗方法。

7. 发明申请

US20130172715A1 ELECTRODE SUPPORT STRUCTURE ASSEMBLIES 有权
标题翻译：电极支撑结构组件
公开(公告)号：US20130172715A1
公开(公告)日：2013-07-04
申请号：US13340760
申请日：2011-12-30
申请人： Dale E. Just , Troy T. Tegg , Theodore A. Johnson
发明人： Dale E. Just , Troy T. Tegg , Theodore A. Johnson
IPC分类号： A61B5/042 , A61B18/00
CPC分类号： A61B5/6859 , A61B5/0422 , A61B5/6858 , A61B18/1492 , A61B2018/00267 , A61B2018/1475 , A61B2218/002 , A61B2562/16
摘要： An electrode support structure assembly is provided comprising an electrode support structure including a plurality of splines. Each of the plurality of splines can have a proximal end portion and a distal end portion. The assembly further comprises a first element defining an axis and comprising an outer surface. The outer surface comprises a plurality of slots configured to receive the distal end portion of each of the plurality of splines. The first element is configured such that the distal end portion of each of the plurality of splines may move with respect to each slot. In accordance with some embodiments, the distal end portion of each of the plurality of splines comprises a section configured for engagement with the first element, wherein the section comprises a shoulder.
摘要翻译：提供了一种电极支撑结构组件，其包括包括多个花键的电极支撑结构。多个花键中的每一个可以具有近端部分和远端部分。组件还包括限定轴线并包括外表面的第一元件。外表面包括被配置为容纳多个花键中的每一个的前端部分的多个槽。第一元件构造成使得多个花键的每一个的远端部分可以相对于每个槽移动。根据一些实施例，多个花键中的每一个的远端部分包括构造成与第一元件接合的部分，其中该部分包括肩部。

8. 发明授权

US08317745B2 Robotic catheter rotatable device cartridge 有权
标题翻译：机器人导管可旋转装置筒
公开(公告)号：US08317745B2
公开(公告)日：2012-11-27
申请号：US12347842
申请日：2008-12-31
申请人： Mark B. Kirschenman , Troy T. Tegg , John A. Hauck
发明人： Mark B. Kirschenman , Troy T. Tegg , John A. Hauck
IPC分类号： A61M31/00
CPC分类号： A61B19/20 , A61B34/30 , A61B34/37 , A61B34/71 , A61B90/10 , A61B2017/003 , A61B2017/00477 , A61B2017/00876 , A61B2034/301 , A61B2090/372 , A61M25/0097 , A61M25/0105
摘要： A robotic catheter rotatable device cartridge may include a housing member attachable to a drive mechanism for rotating the cartridge and a catheter attached to the cartridge along an axial direction of the catheter. A slider block may be generally slidable relative to the housing and engaged with one or more steering wires for controlling movement of the catheter in a transverse direction relative to the axial direction. The catheter may include the steering wire(s) engaged therewith and movable in the transverse direction when the slider block is linearly driven in a predetermined direction.
摘要翻译：机器人导管可旋转装置筒可以包括可附接到驱动机构的壳体构件，用于使筒旋转，以及沿着导管的轴向连接到筒的导管。滑动块通常可相对于壳体滑动并与一个或多个操纵线接合，用于控制导管相对于轴向方向的横向移动。导管可以包括与其接合的操纵线，并且当滑动块沿预定方向被线性驱动时可以在横向上移动。

9. 发明授权

US07823258B2 Self-locking wire lock 有权
标题翻译：自锁线锁
公开(公告)号：US07823258B2
公开(公告)日：2010-11-02
申请号：US11647349
申请日：2006-12-29
申请人： Troy T. Tegg
发明人： Troy T. Tegg
IPC分类号： F16B37/12
CPC分类号： A61M25/0133 , A61M25/01 , A61M2025/09125 , Y10T24/3969 , Y10T24/3996
摘要： A wire lock includes a body having an opening therethrough, a locking member disposed at least partially within the opening, and a biasing device. The biasing device urges the locking member into a configuration wherein a wire passing through the opening is restrained in at least one direction, and may operate in either tension or compression. The locking member may include one or more locking elements that are compressed about the wire through engagement with a wedge-shaped locking section of the body, with the biasing member urging the locking member against the locking section. In other embodiments, the locking member is a locking pin riding on an inclined surface of an elongate slot extending across the body, with the biasing member urging the locking pin against one end of the slot, and the wire pinched between the pin and a body surface opposite the inclined surface.
摘要翻译：线锁包括具有穿过其中的开口的本体，至少部分地设置在开口内的锁定构件和偏置装置。偏置装置将锁定构件推动成通过开口的线在至少一个方向上被限制的构造，并且可以以张力或压缩方式操作。锁定构件可以包括一个或多个锁定元件，其通过与主体的楔形锁定部分接合而围绕电线压缩，偏置构件将锁定构件推向锁定部分。在其它实施例中，锁定构件是一个锁定销，该锁定销位于延伸穿过主体的细长槽的倾斜表面上，偏置构件将锁定销推压到狭槽的一端，并且夹在销和主体之间的电线表面与倾斜面相对。

10. 发明申请

US20100073150A1 ROBOTIC CATHETER SYSTEM INCLUDING HAPTIC FEEDBACK 有权
标题翻译：机器人导管系统，包括HAPTIC反馈
公开(公告)号：US20100073150A1
公开(公告)日：2010-03-25
申请号：US12507175
申请日：2009-07-22
申请人： Eric S. Olson , Mark B. Kirschenman , Troy T. Tegg , John A. Hauck
发明人： Eric S. Olson , Mark B. Kirschenman , Troy T. Tegg , John A. Hauck
IPC分类号： H04B3/36 , A61M25/01
CPC分类号： A61B34/30 , A61B34/74 , A61B34/76 , A61B34/77 , A61B2017/00026 , A61B2034/301 , A61B2034/741 , A61B2034/742 , A61B2090/064 , A61B2090/065 , A61M25/0105
摘要： A haptic feedback system for a robotic catheter system including a robotic catheter manipulator assembly including one or more removably mounted robotic catheter device cartridges and robotic sheath device cartridges, with each cartridge being generally linearly movable relative to the robotic catheter manipulator assembly. The haptic feedback system may include a user interface device for controlling an operation associated with the catheter and/or sheath device cartridges, and a control system for evaluating a predetermined and/or a measured operational parameter of the haptic feedback system. The user interface device may provide haptic feedback to a user based on the evaluation by the control system.
摘要翻译：一种用于机器人导管系统的触觉反馈系统，其包括机器人导管操纵器组件，其包括一个或多个可拆卸地安装的机器人导管装置盒和机器人护套装置盒，每个盒通常可相对于机器人导管操纵器组件线性移动。触觉反馈系统可以包括用于控制与导管和/或鞘装置盒相关联的操作的用户界面装置，以及用于评估触觉反馈系统的预定和/或测量的操作参数的控制系统。用户界面设备可以基于控制系统的评估来向用户提供触觉反馈。

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