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1. 发明申请

US20080015568A1 Dynamic contact assessment for electrode catheters 有权
标题翻译：电极导管的动态接触评估
公开(公告)号：US20080015568A1
公开(公告)日：2008-01-17
申请号：US11549100
申请日：2006-10-12
申请人： Saurav Paul , Chou Thao , Kedar Belhe , Reed Heimbecher
发明人： Saurav Paul , Chou Thao , Kedar Belhe , Reed Heimbecher
IPC分类号： A61B18/18
CPC分类号： A61B5/036 , A61B5/061 , A61B5/6885 , A61B18/1492 , A61B2018/00351 , A61B2090/065
摘要： An electrode catheter and a method for assessing catheter-tissue contact for tissue ablation are disclosed. An exemplary electrode catheter comprises a flexible catheter shaft. At least one piezoelectric sensor is oriented coaxial to the flexible catheter shaft. The at least one piezoelectric sensor is responsive to movement of the flexible catheter shaft by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one piezoelectric sensor. The output device receives the electrical signals for dynamically assessing a level of contact between the flexible catheter shaft and a moving tissue. In another exemplary embodiment, the system may be implemented in a hydrodynamic environment.
摘要翻译：公开了电极导管和用于评估用于组织消融的导管 - 组织接触的方法。示例性电极导管包括柔性导管轴。至少一个压电传感器与柔性导管轴同轴地定向。至少一个压电传感器通过产生对应于移动量的电信号来响应柔性导管轴的移动。该系统还可以包括电连接到至少一个压电传感器的输出装置。输出装置接收用于动态评估柔性导管轴和移动组织之间的接触程度的电信号。在另一个示例性实施例中，系统可以在流体动力学环境中实现。

2. 发明申请

US20080091192A1 Brush electrode and method for ablation 审中-公开
标题翻译：刷电极和消融方法
公开(公告)号：US20080091192A1
公开(公告)日：2008-04-17
申请号：US11953151
申请日：2007-12-10
申请人： Saurav Paul , Kedar Belhe , Hong Cao , Chou Thao
发明人： Saurav Paul , Kedar Belhe , Hong Cao , Chou Thao
IPC分类号： A61B18/14
CPC分类号： A61B18/1402 , A61B2018/143 , A61B2018/1472
摘要： A brush electrode and a method for using the brush electrode for tissue ablation are disclosed. The brush electrode comprises a plurality of flexible filaments or bristles for applying ablative energy (e.g., RF energy) to target tissue during the formation of spot or continuous linear lesions. Interstitial spaces are defined among the filaments of the brush electrode, and the interstitial spaces are adapted to direct conductive or nonconductive fluid, when present, toward the distal ends of the brush filaments. The brush electrode facilitates electrode-tissue contact in target tissue having flat or contoured surfaces. The flexible filaments may be selectively trimmed to give a desired tip configuration or a desired standoff distance between the tissue and the conductive filaments in the brush electrode. Also, the filaments may be grouped into clusters. A shielded-tip brush electrode, including a flexible boot, is also disclosed.
摘要翻译：公开了一种刷电极和使用刷电极进行组织消融的方法。刷电极包括多个柔性细丝或刷毛，用于在形成斑点或连续线性损伤期间向靶组织施加消融能量（例如RF能量）。间隙空间被限定在刷电极的细丝之间，并且间隙空间适于将导电或非导电流体（当存在时）引向刷丝的远端。刷电极促进具有平坦或轮廓表面的靶组织中的电极组织接触。可以选择性地修剪柔性细丝以给出组织和刷电极中的导电细丝之间的期望的尖端构型或期望的间隔距离。此外，丝可以分组成簇。还公开了一种包括柔性护罩的屏蔽尖刷电极。

3. 发明申请

US20070293856A1 Side-port sheath for catheter placement and translation 有权
公开(公告)号：US20070293856A1
公开(公告)日：2007-12-20
申请号：US11892817
申请日：2007-08-27
申请人： Saurav Paul , Kedar Belhe , Hong Cao , John Roop , Chou Thao
发明人： Saurav Paul , Kedar Belhe , Hong Cao , John Roop , Chou Thao
IPC分类号： A61B18/08
CPC分类号： A61B18/1492 , A61B5/042 , A61B2018/143 , A61B2018/1475 , A61B2018/1497
摘要： Side-port sheaths for catheter placement and translation are disclosed. The sheaths include a side-port opening through which a gliding catheter may be deployed during diagnosis or treatment of tissue. The side-port sheath may include a suspension ribbon used to deploy, or that aids in the deployment of, the embedded gliding catheter. The suspension ribbon may be slideably or fixably engaged with an outer surface of the sheath of the gliding catheter.

4. 发明申请

US20050267467A1 Bipolar conforming electrode catheter and methods for ablation 审中-公开
标题翻译：双极符合电极导管和消融方法
公开(公告)号：US20050267467A1
公开(公告)日：2005-12-01
申请号：US11190724
申请日：2005-07-27
申请人： Saurav Paul , Kedar Belhe , Chou Thao
发明人： Saurav Paul , Kedar Belhe , Chou Thao
IPC分类号： A61B18/14
CPC分类号： A61B18/1402 , A61B18/16 , A61B2018/143
摘要： A bipolar conforming electrode catheter has a plurality of flexible filaments or bristles forming a brush electrode for applying therapeutic energy (e.g., RF energy) to target tissue to form spot or continuous linear lesions. Interstitial spaces are defined among the filaments of the brush electrode. The interstitial spaces are adapted to direct conductive or nonconductive fluid, when present, toward the distal ends of the filaments. The brush electrode facilitates electrode-tissue contact in target tissue having flat or contoured surfaces. The flexible filaments may be selectively trimmed to give a desired tip configuration or a desired standoff distance between the tissue and the conductive filaments in the brush electrode. The filaments may be grouped into clusters. The catheter includes a dispersive return electrode for bipolar function.
摘要翻译：双极符合电极导管具有形成刷电极的多个柔性细丝或刷毛，用于向靶组织施加治疗能量（例如RF能量）以形成点或连续的线性损伤。在刷电极的长丝之间限定间隙空间。间隙空间适于将导电或非导电流体（当存在时）引向长丝的远端。刷电极促进具有平坦或轮廓表面的靶组织中的电极组织接触。可以选择性地修剪柔性细丝以给出组织和刷电极中的导电细丝之间的期望的尖端构型或期望的间隔距离。细丝可以分组成簇。该导管包括用于双极功能的分散返回电极。

5. 发明申请

US20050159741A1 Conforming-electrode catheter and method for ablation 有权
标题翻译：符合电极导管及消融方法
公开(公告)号：US20050159741A1
公开(公告)日：2005-07-21
申请号：US10856926
申请日：2004-05-27
申请人： Saurav Paul , Kedar Belhe , Hong Cao , Chou Thao
发明人： Saurav Paul , Kedar Belhe , Hong Cao , Chou Thao
IPC分类号： A61B18/14 , A61N1/04
CPC分类号： A61B18/1402 , A61B2018/143 , A61B2018/1472
摘要： A brush electrode catheter and a method for using the brush electrode catheter for tissue ablation are disclosed. The brush electrode catheter comprises a plurality of flexible filaments or bristles for applying ablative energy (e.g., RF energy) to target tissue during the formation of spot or continuous linear lesions. Interstitial spaces are defined among the filaments of the brush electrode, and the interstitial spaces are adapted to direct conductive or nonconductive fluid, when present, toward the distal ends of the brush filaments. The brush electrode facilitates electrode-tissue contact in target tissue having flat or contoured surfaces. The flexible filaments may be selectively trimmed to give a desired tip configuration or a desired standoff distance between the tissue and the conductive filaments in the brush electrode. Also, the filaments may be grouped into clusters. A shielded-tip brush electrode, including a flexible boot, is also disclosed.
摘要翻译：公开了一种刷电极导管和用于组织消融的刷电极导管的方法。刷电极导管包括多个柔性细丝或刷毛，用于在形成斑点或连续线性病变期间向靶组织施加消融能量（例如RF能量）。间隙空间被限定在刷电极的细丝之间，并且间隙空间适于将导电或非导电流体（当存在时）引向刷丝的远端。刷电极促进具有平坦或轮廓表面的靶组织中的电极组织接触。可以选择性地修剪柔性细丝以给出组织和刷电极中的导电细丝之间的期望的尖端构型或期望的间隔距离。此外，丝可以分组成簇。还公开了一种包括柔性护罩的屏蔽尖刷电极。

6. 发明申请

US20050159739A1 Brush electrode and method for ablation 有权
标题翻译：刷电极和消融方法
公开(公告)号：US20050159739A1
公开(公告)日：2005-07-21
申请号：US10808919
申请日：2004-03-24
申请人： Saurav Paul , Kedar Belhe , Hong Cao , Chou Thao
发明人： Saurav Paul , Kedar Belhe , Hong Cao , Chou Thao
IPC分类号： A61B18/14
CPC分类号： A61B18/1402 , A61B2018/143 , A61B2018/1472
摘要： A brush electrode and a method for using the brush electrode for tissue ablation are disclosed. The brush electrode comprises a plurality of flexible filaments or bristles for applying ablative energy (e.g., RF energy) to target tissue during the formation of spot or continuous linear lesions. Interstitial spaces are defined among the filaments of the brush electrode, and the interstitial spaces are adapted to direct conductive or nonconductive fluid, when present, toward the distal ends of the brush filaments. The brush electrode facilitates electrode-tissue contact in target tissue having flat or contoured surfaces. The flexible filaments may be selectively trimmed to give a desired tip configuration or a desired standoff distance between the tissue and the conductive filaments in the brush electrode. Also, the filaments may be grouped into clusters. A shielded-tip brush electrode, including a flexible boot, is also disclosed.
摘要翻译：公开了一种刷电极和使用刷电极进行组织消融的方法。刷电极包括多个柔性细丝或刷毛，用于在形成斑点或连续线性损伤期间向靶组织施加消融能量（例如RF能量）。间隙空间被限定在刷电极的细丝之间，并且间隙空间适于将导电或非导电流体（当存在时）引向刷丝的远端。刷电极促进具有平坦或轮廓表面的靶组织中的电极组织接触。可以选择性地修剪柔性细丝以给出组织和刷电极中的导电细丝之间的期望的尖端构型或期望的间隔距离。此外，丝可以分组成簇。还公开了一种包括柔性护罩的屏蔽尖刷电极。

7. 发明申请

US20060287650A1 Ablation catheter with fluid distribution structures 有权
标题翻译：消融导管与流体分布结构
公开(公告)号：US20060287650A1
公开(公告)日：2006-12-21
申请号：US11158944
申请日：2005-06-21
申请人： Hong Cao , Chou Thao , Kedar Belhe , Saurav Paul , Todd Stangenes
发明人： Hong Cao , Chou Thao , Kedar Belhe , Saurav Paul , Todd Stangenes
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00375 , A61B2018/1472
摘要： An ablation catheter has improved fluid distribution structures. An ablation section at a distal end of the catheter is designed to provide a more uniform fluid flow emanating from the catheter. By creating a uniform fluid flow, a more uniform tissue lesion results and the possibility of charring the tissue is reduced. A combination of mesh material layers, porous materials, and dispersion channels or openings are used to achieve the uniform flow. The amount of fluid used as a virtual electrode to ablate the tissue is greatly reduced with the present invention. Further, the catheter may be used to create a single, uniform linear lesion by successive application of energy to adjacent portions of the ablation section, thus reducing the power required to create the desired lesion.
摘要翻译：消融导管具有改善的流体分布结构。在导管的远端处的消融部分被设计成提供从导管发出的更均匀的流体流动。通过产生均匀的流体流动，会产生更均匀的组织损伤，并且减少了烧结组织的可能性。使用网状材料层，多孔材料和分散通道或开口的组合来实现均匀的流动。用于消除组织的虚拟电极的流体的量通过本发明大大减少。此外，导管可用于通过将能量连续施加到消融部分的相邻部分来产生单一的均匀的线性损伤，从而减少产生所需损伤所需的功率。

8. 发明申请

US20050267458A1 Side-port sheath for catheter placement and translation 失效
标题翻译：用于导管放置和翻译的侧端口护套
公开(公告)号：US20050267458A1
公开(公告)日：2005-12-01
申请号：US10856145
申请日：2004-05-27
申请人： Saurav Paul , Kedar Belhe , Hong Cao , John Roop , Chou Thao
发明人： Saurav Paul , Kedar Belhe , Hong Cao , John Roop , Chou Thao
IPC分类号： A61B5/04 , A61B5/042 , A61B18/14 , A61N1/05
CPC分类号： A61B18/1492 , A61B5/042 , A61B2018/143 , A61B2018/1475 , A61B2018/1497
摘要： Side-port sheaths for catheter placement and translation are disclosed. The sheaths include a side-port opening through which a gliding catheter may be deployed during diagnosis or treatment of tissue. The side-port sheath may include a suspension ribbon used to deploy, or that aids in the deployment of, the embedded gliding catheter. The suspension ribbon may be slideably or fixably engaged with an outer surface of the sheath of the gliding catheter.
摘要翻译：公开了用于导管放置和平移的侧端口护套。护套包括侧口开口，在组织的诊断或处理期间可以通过滑动导管展开滑动导管。侧端口护套可以包括用于部署或有助于部署嵌入式滑翔导管的悬挂带。悬挂带可以与滑动导管的护套的外表面可滑动地或可固定地接合。

9. 发明申请

US20050159740A1 Surgical device with brush electrode and methods for electrosurgical treatment 有权
标题翻译：带刷电极的手术装置和电外科治疗方法
公开(公告)号：US20050159740A1
公开(公告)日：2005-07-21
申请号：US10856925
申请日：2004-05-27
申请人： Saurav Paul , Kedar Belhe , Hong Cao , Chou Thao
发明人： Saurav Paul , Kedar Belhe , Hong Cao , Chou Thao
IPC分类号： A61B18/14 , A61N1/04
CPC分类号： A61B18/1402 , A61B2018/143 , A61B2018/1472
摘要： A surgical device incorporates a brush electrode for tissue ablation and other forms of electrosurgical treatment. A plurality of flexible filaments compose the brush electrode, through which therapeutic energy (e.g., RF energy) is applied to target tissue for the formation of spot or continuous linear lesions, cauterization, incision, and desiccation. A fluid delivery system is used in conjunction with the brush electrode to apply fluid to the filaments and surgical site.
摘要翻译：手术装置包括用于组织消融的刷电极和其他形式的电外科治疗。多个柔性细丝构成刷电极，通过该刷电极将治疗能量（例如，RF能量）施加到靶组织以形成斑点或连续线性病变，烧灼，切口和干燥。流体输送系统与刷电极结合使用以将流体施加到细丝和手术部位。

10. 发明申请

US20050267332A1 Spring-tip, flexible electrode catheter for tissue ablation 有权
标题翻译：弹簧尖端，柔性电极导管用于组织消融
公开(公告)号：US20050267332A1
公开(公告)日：2005-12-01
申请号：US10856904
申请日：2004-05-27
申请人： Saurav Paul , Kedar Belhe , Hong Cao , John Roop , Chou Thao
发明人： Saurav Paul , Kedar Belhe , Hong Cao , John Roop , Chou Thao
IPC分类号： A61B18/14 , A61N1/05
CPC分类号： A61B18/1492 , A61B2018/143 , A61B2018/1435
摘要： A spring-tip, flexible electrode, and a method for using that electrode for tissue ablation, are disclosed. The spring-tip, flexible electrode comprises an enshrouded flexible electrode (e.g., an enshrouded plurality of flexible brush filaments or bristles) for applying ablative energy (e.g., RF energy) to target tissue during the formation of spot or continuous linear lesions. The spring of the spring tip may comprise compressible coils, compressible mesh, or compressible bellows, among other things. The spring provides axial suspension and is capable of axial compression and extension, and is flexible enough for deflection and bending. The axial suspension of the spring tip facilitates the desired contact between the electrode and the tissue surface. A shielded, spring-tip, flexible electrode is also disclosed, and includes a flexible nipple or shield. The spring-tip, flexible electrode facilitates enhanced tissue contact in difficult environments (e.g., during ablation of a contoured or trabeculated surface inside a beating heart) since the flexible electrode readily conforms to surface contours while the bending stress of the spring enhances the contract pressure on the tissue.
摘要翻译：公开了一种弹簧尖端，柔性电极和用于组织消融使用该电极的方法。弹簧尖端的柔性电极包括用于在形成斑点或连续的线性损伤期间向目标组织施加消融能量（例如，RF能量）的带有屏蔽的柔性电极（例如，被包围的多个柔性刷丝或刷毛）。弹簧尖端的弹簧可以包括可压缩线圈，可压缩网或可压缩波纹管等等。弹簧提供轴向悬挂并且能够轴向压缩和伸展，并且具有足够的挠性和弯曲性。弹簧顶端的轴向悬挂有助于电极和组织表面之间的所需接触。还公开了屏蔽的弹簧尖端柔性电极，并且包括柔性接头或屏蔽。弹簧尖端的柔性电极有助于在困难的环境中（例如在跳动心脏内的轮廓或小梁表面的消融期间）增强组织接触，因为柔性电极容易符合表面轮廓，同时弹簧的弯曲应力增加了收缩压力在纸巾上。

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